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1.
Thermal Science ; 26(2):1219-1228, 2022.
Article in English | English Web of Science | ID: covidwho-1883848

ABSTRACT

The paper contains a response to the comment by Popovich and Mincheva, focusing on the different meanings of the analysis according to the First and the Second law of thermodynamics and their complementary and never alternative nature.

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American Journal of Respiratory and Critical Care Medicine ; 205:1, 2022.
Article in English | English Web of Science | ID: covidwho-1880374
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Acta Neurologica Taiwanica ; 31(4):167-170, 2022.
Article in English | Scopus | ID: covidwho-1877042

ABSTRACT

Purpose: To highlight the factors leading to the delayed diagnosis of basilar artery occlusion and poor outcome in the postpartum period during the prevailing Corona Virus Disease-2019 (COVID-19) pandemic. Case report: We here report a case of a 34-year female who presented with a headache localized to the occipital region after cesarean section under spinal anesthesia. Her headache severity increased over time, and she developed a generalized seizure episode and became unconscious. Subsequently, basilar artery thrombosis was diagnosed. Despite all efforts, she succumbed to death. We believe that we might have saved the patient's life if we could have made the diagnosis beforehand. Conclusion: We recommend that unless shown otherwise, postpartum headache and neck discomfort, even in individuals with no known risk factors, should have a low index of suspicion, early diagnosis using non-invasive radiological study such MRI to rule out this uncommon but deadly illness quickly. © 2022, Neurological Society R.O.C (Taiwan). All rights reserved.

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1st International Conference on Technologies for Smart Green Connected Society 2021, ICTSGS 2021 ; 107:9439-9444, 2022.
Article in English | Scopus | ID: covidwho-1874828

ABSTRACT

COVID-19 spread has impacted all shards of life of larger population around the world, the effect remained devastating in developing countries with poor to average health infrastructure. In many developing countries like India where agriculture always remain backbone of economy and power livelihood to large segment of rural masses, COVID-19 spread created huge consequences on general health, livelihoods, and sustainability of rural economy. Unrehearsed mechanism, processes, and policies has given a big blow to informal rural economy. The paper is an attempt to comprehensively measure the effect of COVID-19 on agriculture, economy, and livelihood of rural India. Research material including secondary data available for various aspect of rural economy has been explored along with various village centric studies conducted and published by different researchers. Researcher also tried to suggest how the livelihood and economy can be protected. © The Electrochemical Society

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1st International Conference on Technologies for Smart Green Connected Society 2021, ICTSGS 2021 ; 107:7165-7178, 2022.
Article in English | Scopus | ID: covidwho-1874807

ABSTRACT

The ongoing pandemic, which is initiated in Wuhan, China, the rapid spread of Coronavirus disease (COVID-19) has caused public health crises regionally and internationally. According to World Health Organization (WHO), the virus can spread from an infected person's mouth or nose. Therefore, WHO has given various guidelines to be followed by people as precautions, among them, wearing a face mask is also one among them. So, in the proposed paper sentiment analysis will be performed to study public views on wearing masks, even after getting vaccinated. The purpose of this study is to analyze tweets by Indian citizens on problems due to wearing masks during the COVID-19 pandemic. Data analysis was conducted by several classification algorithms based on Artificial Immune System algorithms (AIS), which are a new deep-learning model for text analysis and performance, and results are also compared with other models such as Naïve Bayes (NB), Support Vector Machines (SVM), etc. © The Electrochemical Society

8.
2020 National Conference on Advances in Applied Sciences and Mathematics, NCASM 2020 ; 2357, 2022.
Article in English | Scopus | ID: covidwho-1873612

ABSTRACT

From the past several year's educational institutions at every level was practicing conventional teaching-learning process. It seems to be the only way of imparting education to the learners. However, due to the onset of Coronavirus, i.e., Covid19, everything came to a halt for a while all over the world. The complete ecosystem of human society gets affected by this. Educational institutions also hit hard by this pandemic, and the complete layout of the teaching-learning process over the globe changed. It brings challenges for both students and teachers to withstand in this tough situation and to restore the backbone of learning. E-learning activities slowly-slowly gripped the complete educational ecosystem and the way of imparting education also changed. The primary purpose of this study is to examine the level of cognition faced by e-learners as compared to traditional learners at higher education level during Covid19. For this study, 120 students from Chitkara University have voluntarily participated and submitted their responses through the Google Form. It deduces from this study that learners using E-learning mode feel more cognitive load as compared to traditional learners. The cohen's d-value which represents the effect size comes to be 0.97 which means that the effect of cognitive load is significantly large on e-learners than the traditional learners. In the future, the reasons behind the rise of the cognition level of e-learners need to evaluate and improve the learning gain of e-learners. © 2022 Author(s).

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International Conference on Artificial Intelligence and Sustainable Engineering, AISE 2020 ; 836:87-100, 2022.
Article in English | Scopus | ID: covidwho-1872349

ABSTRACT

Due to COVID-19 situation, online retailing (electronic retailing) for purchasing goods has recently increased which leads to the need of customer segmentation. Customer segmentation is done based on customers’ past purchase behavior and then divide them into different categories, i.e., loyal customer, potential customer, new customer, customer needs attention, customers require activation. This paper uses recency, frequency, monetary value (RFM) analysis and K-means clustering technique for grouping the customers. Further to enhance the efficiency of segmentation, a decision tree is used to create nested splitting (based on Gini index) inside the each cluster. The implementation of proposed hybrid approach is showing promising results for customer segmentation to take better management decisions. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Radiotherapy and Oncology ; 170:S1343-S1344, 2022.
Article in English | PMC | ID: covidwho-1867929
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Journal of Global Health Reports ; 5(e2021069), 2021.
Article in English | GIM | ID: covidwho-1865734

ABSTRACT

Background: There are various COVID-19 vaccines launched in different parts of the world. As the vaccination drive is increasing, the reports of adverse events following immunization (AEFI) are increasingly reported. Therefore, this research aims to document the adverse events and their determinants following COVID-19 vaccination.

12.
Indian Journal of Agricultural Sciences ; 92(4):469-473, 2022.
Article in English | CAB Abstracts | ID: covidwho-1864084

ABSTRACT

To critically assess the performance of micro and small foodpreneurs during COVID-19 pandemic in Manipur state of India, an online survey was conducted during the year 2020. The survey data was subjected to non-parametric statistical analysis using PROC NPAR1WAY and Dwass, Steel, Critchlow-Fligner multiple comparison analysis. The findings suggested that during COVID-19 pandemic, the micro and small foodpreneurs faced multifaceted challenges with respect to the number of employees, working hours, supply of raw material, selling mode, production, sale, turnover and the extent of loss, etc. The performance of different categories of foodpreneurs was compared based on the change in various performance indicators between pre-pandemic and pandemic period. The study also highlights the major problems faced by the foodpreneurs and remedial measures. This is the first report on the impact of COVID-19 pandemic on foodpreneurs from North East India.

13.
Medicinal Plants ; 14(1):30-45, 2022.
Article in English | EMBASE | ID: covidwho-1863214

ABSTRACT

Respiratory viral infections are a major public health concern because of their global occurrence, ease of spread and considerable morbidity and mortality. Medical treatments for viral respiratory diseases primarily involve providing relief from symptoms like pain and discomfort rather than treating the infection. Very few antiviral medications have been approved with restrictive usage, high cost, unwanted side effects and limited availability. Plants with their unique metabolite composition and high remedial values offer unique preventive and therapeutic efficacy in treatment of viral infections. The present review is focused on the types and mode of action of plant secondary metabolites that have been used successfully ί in the treatment of infections caused by respiratory viruses like Influenza, SARS, MERS, RSV etc. Plant metabolites such as phenolics, alkaloids, terpenoids and oligosaccharides inhibit attachment and entry of the virus. Others such as flavonoids, viz quercetin and baicalein, alkaloids viz sanguinarine, berberine and emetine, specific lipids and fatty acids prevent viral replication and protein synthesis. These metabolites have the potential to be used as lead molecules that can be optimized to develop potent drugs for effectively combating pandemics caused by respiratory viruses.

14.
Embase; 2022.
Preprint in English | EMBASE | ID: ppcovidwho-337415

ABSTRACT

The SARS-CoV-2 spike protein is the target of neutralizing antibodies and the immunogen used in all currently approved vaccines. The global spread of the virus has resulted in emergence of lineages which are of concern for the effectiveness of immunotherapies and vaccines based on the early Wuhan isolate. Here we describe two SARS-CoV-2 isolates with large deletions in the N-terminal domain (NTD) of the spike. Cryo-EM structural analysis showed that the deletions result in complete reshaping of the antigenic surface of the NTD supersite. The remodeling of the NTD affects binding of all tested NTD-specific antibodies in and outside of the NTD supersite for both spike variants. A unique escape mechanism with high antigenic impact observed in the ΔN135 variant was based on the loss of the Cys15-Cys136 disulfide due to the P9L-mediated shift of the signal peptide cleavage site and deletion of residues 136-144. Although the observed large loop and disulfide deletions are rare, similar modifications became independently established in several other lineages, highlighting the possibility of a general escape mechanism via the NTD supersite. The observed plasticity of the NTD foreshadows its broad potential for immune escape with the continued spread of SARS-CoV-2.

15.
Int J Environ Sci Technol (Tehran) ; : 1-10, 2021 Jun 30.
Article in English | MEDLINE | ID: covidwho-1859156

ABSTRACT

This study estimates the potential source regions contributing to PM2.5 in the capital city of Thimphu, Bhutan, during the years 2018-2020 using the ground-based data, followed by the HYSPLIT back trajectory analysis. The average PM2.5 concentration in the entire study period was 32.47 µg/m3 which is three times of the World Health Organization recommended limit of 10 µg/m3. Less than half of the days in pre-monsoon (43.47%) and post-monsoon (46.41%), and no days in winter were within the 24-h average WHO guideline of 25 µg/m3. During the COVID-19 lockdown imposed from August 11 to September 21 in Bhutan, only a marginal reduction of 4% in the PM2.5 concentrations was observed, indicating that nonlocal emissions dominate the PM2.5 concentrations in Thimphu, Bhutan. Most back trajectories in the analysis period were allocated to south or south-west sector. India was the major contributor (~ 44%), followed by Bangladesh (~ 19%), Bhutan itself (~ 19%) and China (~ 16%). This study confirms that there are significant contributions from transboundary sources to PM2.5 concentrations in Thimphu, Bhutan, and the elevated PM2.5 concentrations need to be tackled with appropriate action plans and interventions.

16.
Arab Gulf Journal of Scientific Research ; 39(Special Issue):48-59, 2021.
Article in English | Scopus | ID: covidwho-1857350

ABSTRACT

Background: Coronavirus disease 2019 (COVID-19) associated inflammatory cytokine storm that worsens COVID-19, relies heavily on the inflammatory response. IL-6, a TH1 cytokine, PCT and CRP have been linked to serious illness and a higher mortality rate. We further tried to evaluate the role of these indicators and their association with clinical severity in COVID-19 patients. Material and Methods: Eighty-three consecutive patients with age ≥18 years with RT-PCR test positive for SARS-CoV-2 were included in the study. Demographic characteristics (age and sex), underlying co-morbidities, symptoms, physical findings, and laboratory tests of the patients were recorded. All patients were categorized as having mild, moderate, and severe COVID-19 disease, according to the Indian Council of Medical Research (ICMR). The levels of IL-6 and PCT were estimated by electrochemiluminescence immunoassay (ECLIA) using Cobas-e411 Immunoassay System, and Quantitative CRP was done by Unicorn-230 automated biochemistry analyzer to find out their correlation with disease severity and outcome. Multiple Regression was performed to find out factors associated with the adverse outcome of the disease. Result: Mean age of patients was 51 years. IL-6, CRP, and PCT levels increased in 73 %, 68.0 %, and 8.2 % patients on admission, respectively. The most common co-morbidity associated with the disease was hypertension (25%), followed by diabetes (24%) and respiratory disease (15%). Increased IL-6, CRP, and PCT levels were found in 77 percent, 79 percent, and 20 percent of patients, respectively. We found that IL-6 (P≤0.05), CRP (P≤0.05), and PCT (P≤0.05) were significantly raised in COVID-19 patients with increasing severity of the disease. The Area under the receiver operating characteristic (AUROC) of these parameters ranged between 0.65 and 0.8 (IL-6, 0.828;CRP, 0.809;and PCT, 0.658), indicating a reliable biomarker to assess clinical severity. Conclusion: Sequential measurement of blood levels of IL-6, CRP, and PCT levels is useful in determining the severity and predicting the outcome of the patients with severe disease. IL-6 and CRP have an independent prognostic value. On the other hand, the importance of normal PCT concentrations in patients with viral pneumonia needs to be studied further. © 2021, Arabian Gulf University. All rights reserved.

17.
International Journal of Early Childhood Special Education ; 14(3):1986-1992, 2022.
Article in English | Web of Science | ID: covidwho-1856295

ABSTRACT

Researcher had finished his data collection and interviewing of domain experts by the first week of March 2021 and had put together the entire paper, the nationwide lock-down due to COVID-19 meant that the final submission/release of this paper was pushed forward by three to four months. Hence, this paper mainly covers the pre-lock-down and post scenario. It took a considerable amount of time to check State-wise details (for all States), rules, loopholes, issues and to find out best practices and key initiatives rolled out across States. There are a few significant developments that took place after 21 March 2020 when the lock-down was announced and till March 2021. COVID-19 should be declared as a Force Majeure event for all construction contracts, Architectural & engineering design contracts under implementation or under service. With the recent increase in the number of COVID-19 cases in India, the likelihood of the lockdown being extended is high. This would only prolong the misery of the already bleeding real estate sector and potentially expose the promoters to a vast number of claims and complaints. On the extension of timelines for delivery of possession, whilst the principles of law will be considered in terms of force majeure clauses in the Agreements and the specific facts of the case, considering the gravity of the present situation, impact of lockdown and the detrimental effect on the economy, we would expect the relevant RERA Authority/ Courts to adopt a more balanced approach and direct resolutions to any disputes in this regard factoring equities.

18.
Journal of Clinical and Diagnostic Research ; 16(4):PC21-PC23, 2022.
Article in English | Web of Science | ID: covidwho-1856270

ABSTRACT

Introduction: Across the globe the healthcare system was severely affected by Coronavirus Disease-19 (COVID-19) pandemic. Measures taken to curtail the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus have severely affected the paediatric patients presenting with Acute Appendicitis (AA). Aim: To assess the impact of COVID-19 on paediatric Acute Appendicities patients at tertiary care center in New Delhi. Materials and Methods: A retrospective analysis of patient demographics, symptomatology including delay in presentation to hospital, haematological, intraoperative findings and complications of all paediatric AA patients who underwent appendectomy from 23rd March 2020 to 22nd July 2020 (Pandemic Group- PG group) were performed. Patients presenting in corresponding time period in the year 2019 were also compared (Non Pandemic Group (NPG) group). Group comparisons for continuously distributed data were made using Independent sample t-test. For non normally distributed data, non parametric tests in the form of Wilcoxon test were used. Chi-squared test was used for group comparisons for categorical data. Results: A total of 72 patients were included with 39 in NPG and 33 in PG group respectively. There were no significant differences between the two groups in terms of age (p-value=0.759) and sex distribution (p-value=0.93). Patients in PG group had higher leukocyte counts as compared to NPG group (16748.48 +/- 7744.08 vs 12510.26 +/- 7736.58, p-value <0.007). There was no significant difference in delay in presentation, symptomatology, duration of hospital stay and postoperative complications rate between the two groups. Conclusion: There has been no significant change in the number of patients presenting with AA and the symptomatology during COVID-19 pandemic.

19.
European Journal of Molecular and Clinical Medicine ; 7(8):3239-3248, 2020.
Article in English | EMBASE | ID: covidwho-1849273

ABSTRACT

Aim: This study is conducted to know the psychological impact of e learning among the students. Background: From the time of very first beginning of civilization to modern days before corona pandemic situation, most of the students of India are very much used to with the offline mode of learning. But now the situation is changed totally. They are getting themselves adapted to the online mode of learning as per need of time. In this changed scenario they are totally disconnected from their usual life with frames schools teachers and society. This situation wreaks havoc to their psychology. Methodology: This study is conducted with primary data in form of online survey. It was conducted with a pre formed questionnaire. 428 responses were collected for the present study. With advanced Excel software statistical analysis done. Outcomes: Results show that students have shown negative impression on online learning and still they are not ready totally psychologically. Still positive answers show neck to neck result, which signifies increasing interest towards e learning. More practices and awareness required before further implementation.

20.
2022 zh Conference on Human Factors in Computing Systems, zh EA 2022 ; 2022.
Article in English | Scopus | ID: covidwho-1846557

ABSTRACT

Human relationships, intimacy and the role of technology within it constantly change, catapulted in 2020 by COVID-19. We take this social rupture as an opportunity to reimagine possible futures for love, friendship, and kinships. Through design futuring and related approaches, we offer five prompts we developed for imagining alternative futures exploring a diverse range of intimacies. Through generating responses to the prompts, we offer alternative intimate futures as well as reflections on how such 'prompts for futuring' can be generative for design research. Our work extends calls for diversifying design futuring, imploring design researchers to consider diverse and inclusive ways of designing for futures, especially for human relationships and intimacy. © 2022 Owner/Author.

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