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1.
Global Journal of Flexible Systems Management ; 2022.
Article in English | Scopus | ID: covidwho-2175279

ABSTRACT

COVID-19 vaccination campaigns have been launched across the globe to mitigate the impact of the COVID-19 disease. However, COVID-19 vaccination campaigns (Vaccination campaigns are the complete process of COVID-19 vaccination campaigns beyond just administrating vaccines.) are a complex multi-stakeholder process, and therefore, it is important to understand the key components and drivers of vaccination campaigns to help devise strategies to increase vaccination coverage for existing and future vaccination efforts. A system dynamics modeling approach was used to trace the vaccination campaign for the Indian state of Madhya Pradesh. The results identified the key stakeholders of the vaccination campaign and their inter-linkages, and the diverse perspectives of stakeholders of vaccination campaigns in Madhya Pradesh were collated in a structured format. Further, system dynamics models were developed to capture all aspects of the vaccination campaign in Madhya Pradesh, including the challenges and innovations. The outcomes of the study can assist academicians, practitioners, and policymakers develop vaccination programs at sub-national, national, and global levels. They will guide decision-makers to take preemptive measures to mitigate possible risks and challenges and provide improved services as part of vaccination campaigns. © 2022, The Author(s).

2.
NeuroQuantology ; 20(21):302-309, 2022.
Article in English | EMBASE | ID: covidwho-2206904

ABSTRACT

Rising cases of corona virus have significantly affected the Indian economy at large. Due to the corona virus outbreak, the Indian economy every day was expected to lose over the US $ 4.5 Billion. (Acuite Ratings). Due to the widespread of covid-19 cases, the Indian Government has lock down the country for quite 60 days which adversely affected commercial activities and the Indian economy. It hinders international trade which in turn stops the import-export of raw materials & hence negatively affected manufacturing at large. Despite the manufacturing sector, various other sectors were also got affected by the corona virus outbreak. The Micro, Small & Medium Enterprises (MSMEs) which are considered to be the backbone of all Indian sectors and also engaged in export activities, has also been impacted by the covid-19 pandemic. MSMEs contributed around 24.63% of GDP from service units as well as 6.11% of the GDP from manufacturing (Confederation of Indian Industry) but this pandemic restricted working and hence made a downfall in the GDP. This paper is based on descriptive analysis based on secondary data. The purpose of the research is to investigate the key areas where the pandemic made its economic influence. It is expected that this study will help design conceptual models for the researcher to overcome this pandemic. Copyright © 2022, Anka Publishers. All rights reserved.

3.
BMC Public Health ; 23(1):117, 2023.
Article in English | MEDLINE | ID: covidwho-2196204

ABSTRACT

BACKGROUND: As COVID-19 continues to impact lives and livelihoods around the world, women and girls are disproportionately affected. Crisis situations and related response measures, such as lockdowns, school closures, and travel restrictions, often exacerbate the adversities and human rights violations faced by adolescent girls. We conducted a rapid review to synthesise evidence on the impact of public health emergencies (PHEs) related to gender-based inequalities among adolescent girls.

4.
NeuroQuantology ; 20(13):2753-2757, 2022.
Article in English | EMBASE | ID: covidwho-2164306

ABSTRACT

Overmost recent five years, Industry 4.0 (I 4.0) has built upspeed and established a vibe of conversation amongpartners, increated countries as well as in emerging nations.most unmistakable justification fordevelopment of I 4.0 is its possible effect on society, economy and assembling. Thus, numerous nations have begun building plans and arrangements to embrace very good quality computerized advances. As of late, this subject has acquired consideration whenepisode of Coronavirus infection unleashed ruin acrossglobe and hugely affectedorganizations and supply chains acrossworld. Copyright © 2022, Anka Publishers. All rights reserved.

5.
Sensing Tools and Techniques for COVID-19: Developments and Challenges in Analysis and Detection of Coronavirus ; : 1-312, 2022.
Article in English | Scopus | ID: covidwho-2149169

ABSTRACT

Sensing Tools and Techniques for COVID-19: Developments and Challenges in Analysis and Detection of Coronavirus helps readers understand the basic principles of sensor development. Sections give a brief overview of the physical and chemical properties of sensing tools and the basics of techniques. With recent advancements in sensing technology, various smart materials and techniques are now being employed for new purposes. In addition, biosensing devices can be tuned at the molecular level to perform better detection of COVID-19. This book covers the various approaches for the development and fabrication of biosensor systems for the analysis of the novel coronavirus. In addition, the book discusses the commercialization and standardization of biosensing technology, along with future perspectives on biosensor technologies used for the analysis and treatment of COVID-19. This book will serve as an up-to-date source of trusted information on biosensor tools and techniques for the analysis of COVID-19. © 2022 Elsevier Inc. All rights reserved.

6.
Journal of the Scientific Society ; 49(2):106-113, 2022.
Article in English | Web of Science | ID: covidwho-2072002

ABSTRACT

The coronavirus disease 2019 pandemic (COVID-19) has led to considerable hike in hospitalizations for pneumonia with multiorgan disease requiring immediate hospital care, maintenance of oxygen saturation level, and severe cases requiring mechanical ventilation. This opens the window of opportunity to microscopic organisms such as different species of fungus including Candida, Aspergillus, Rhizopus, and Cryptococcus adding other fungi causing opportunistic invasive fungal infections (OIFIs), and other bacteria to cause concurrent infections in COVID-19-diseased patients which on occasion not promptly diagnosed and are mostly diagnosed after death, which get chance due to invasive procedures such as intubation and immunosuppressant drugs which mostly consists of corticosteroids, patient with diabetes mellitus or any other chronic disease causing immunosuppression, patient having a history of chronic obstructive airway disease, development of antibiotic resistance, and vulnerability of pulmonary tissues regarding developing colony for mycotic infections. In this review, we talk over the character of mycotic concurrent infections in aggravation of COVID-19 disease severity and focus on arising trends associated with fungal infections in coronavirus-diseased (COVID-19 diseased) cases. In addition, this review impart the view on the risky component for concurrent mycotic infections in COVID-19 diseased patients who are hospitalized and focuses the possible task of extended immunemodulatory treatments in managing concurrent mycotic infections, comprising COVID-19-associated pulmonary aspergillosis, COVID-19-associated Candidiasis, and mucormycosis. This article restates the demand for prompt detection regarding presumed COVID-19-related systematic mycosis in the health-care settings which could empower fast OIFI diagnosis, treatment, and lowers the mortality rate.

7.
Journal of Clinical and Diagnostic Research ; 16(9):OD01-OD03, 2022.
Article in English | EMBASE | ID: covidwho-2044184

ABSTRACT

Mucormycosis or zygomycosis is a life threatening invasive fungal infection, usually seen in patients with alteration of their immune system. It is a lethal and an aggressive fungal infection caused by the fungi of the order Mucorales. The angioinvasive property of mucormycosis can lead to fatal complications such as intracranial bleed. Acute pancreatitis refers to inflammation of the pancreas which presents mainly as acute pain in the abdomen and is a potentially fatal condition. The association of mucormycosis with acute pancreatitis is rare but dangerous. This case report highlights a case of 32-year-old male patient, with no co-morbidities, who was admitted to an rural central Indian hospital with four days of abdominal pain and two days of headache. Patient appeared to be in good health prior to this event. He was ultimately diagnosed with mucormycosis of paranasal sinus with acute pancreatitis. The patient was treated with intravenous antifungals, antibiotics and fluid therapy along with other supportive measures. Patient later developed intracranial bleed five days after admission, and ultimately succumbed on day seven of admission. After an extensive review of literature it was found that this is the first article to report mucormycosis, acute pancreatitis and intracranial bleed all occurring at once in an immunocompetent male.

8.
Kidney international reports ; 7(9):S467-S467, 2022.
Article in English | EuropePMC | ID: covidwho-2034108
9.
Indian Journal of Community Health ; 34(2):248-253, 2022.
Article in English | Scopus | ID: covidwho-1989117

ABSTRACT

The most important aspect of Public Health Emergency Preparedness (PHEP) involves the circulation of trustworthy and accurate information in the public health interest domain. Strict stringency measures such as nationwide lockdown impacted people's mental health. Hence, this study was planned to assess the knowledge, practice, and anxiety among the Indian population about the ongoing pandemic in the initial phase. Methods: A web-based cross-sectional study was conducted between August 1, 2020, to October 5, 2020. Coronavirus Anxiety Scale was used to determine dysfunctional anxiety. Results: Among 553 participants, 73.6% had overall good knowledge of COVID-19 with mean correct score of 6.9±1.1. Majority of participants (97%) wore mask regularly, and 93% of respondents regularly washed their hands with soap and water. Only 14 participants scored ≥9 on CAS, suggesting probable cases of dysfunctional anxiety associated with the COVID-19 crisis. Conclusion: The knowledge and practices of citizens in a nation reflect their preparedness and ability to deal with a pandemic of such proportion. Good knowledge translates to good practices and therefore reduces anxiety among the population. It is deemed necessary that people's knowledge and habits, including the mental impact, be accessed at periodic intervals to track their adaptation to pandemics over time. © 2022, Indian Association of Preventive and Social Medicine. All rights reserved.

10.
International Conference on Data Science, Computation, and Security, IDSCS 2022 ; 462:189-197, 2022.
Article in English | Scopus | ID: covidwho-1971617

ABSTRACT

In the current context of the COVID-19 pandemic, due to restrictions in mobility and the closure of schools, people had to shift to work from home. India has the world’s second-largest pool of internet users, yet half its population lacks internet access or knowledge to use digital services. The shift to online mediums for education has exposed the stark digital divide in the education system. The digitization of education proved to be a significant challenge for students who lacked the devices, internet facility, and infrastructure to support the online mode of education or lacked the training to use these devices. These challenges raise concerns about the effectiveness of the future of education, as teachers and students find it challenging to communicate, connect, and assess meaningful learning. This study was conducted at one of the universities in India using a purposive sampling method to understand the challenges faced by the students during the online study and their satisfaction level. This paper aims to draw insight from the survey into the concerns raised by students from different backgrounds while learning from their homes and the decline in the effectiveness of education. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

11.
International Conference on Data Science, Computation, and Security, IDSCS 2022 ; 462:53-68, 2022.
Article in English | Scopus | ID: covidwho-1971616

ABSTRACT

Face recognition has been the most successful image processing application in recent times. Most work involving image analysis uses face recognition to automate attendance management systems. Face recognition is an identification process to verify and authenticate the person using their facial features. In this study, an intelligent attendance management system is built to automate the process of attendance. Here, while entering, a person’s image will get captured. The model will detect the face;then the liveness model will verify whether there is any spoofing attack, then the masked detection model will check whether the person has worn the mask or not. In the end, face recognition will extract the facial features. If the person’s features match the database, their attendance will be marked. In the face of the COVID-19 pandemic, wearing a face mask is mandatory for safety measures. The current face recognition system is not able to extract the features properly. The Multi-task Cascaded Convolutional Networks (MTCNN) model detects the face in the proposed method. Then a classification model based on the architecture of MobileNet V2 is used for liveness and mask detection. Then the FaceNet model is used for extracting the facial features. In this study, two different models for the recognition have been built, one for people with masks another one for people without masks. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

12.
2022 IEEE International Conference on Distributed Computing and Electrical Circuits and Electronics, ICDCECE 2022 ; 2022.
Article in English | Scopus | ID: covidwho-1932097

ABSTRACT

Depression is an unfamous mental health disorder that has affected half the population worldwide. In December 2019, the break of the COVID-19 pandemic was first spotted in Wuhan, China, and later spread to 212 countries and territories worldwide, impacting half the population. It took a significant toll on their physical health and their mental health. Many among the population lost their loved ones, businesses, and being in quarantine for years, completely shifted to the online mode made everyone's life miserable. Many may be dealing with escalated levels of alcohol and drug use, sleeplessness, and an anxious state of mind. So, the need to address this and help the severely affected ones is significant. Self-quarantine also causes additional stress and challenges the mental health of citizens. This paper intends to identify the people who were mentally affected by the pandemic using machine learning techniques. A survey was conducted among college-going students and professionals. The paper used classification techniques such as Naive Bayes, KNN, Random Forest, Logistic Regression, k-fold cross-validation to get results. Support Vector Machine gave the maximum accuracy of 99.35%. © 2022 IEEE.

13.
1st International Conference on Technologies for Smart Green Connected Society 2021, ICTSGS 2021 ; 107:12347-12356, 2022.
Article in English | Scopus | ID: covidwho-1874848

ABSTRACT

This research has focused on the concept of influencer marketing and its impact on consumers of the travel and tourism industry. The goal was to find out whether travel and tourism companies through influencer marketing can attract consumers in this post-Covid situation or not. For this purpose, empirical data were collected from fifty social media users who are following at least one travel influencer on any social media site. From their responses collected by sharing survey questionnaire, it was found that most of the participants are not influenced by social media influencers in terms of deciding where they would travel. © The Electrochemical Society

14.
Clinical Cancer Research ; 27(6 SUPPL 1), 2021.
Article in English | EMBASE | ID: covidwho-1816923

ABSTRACT

Plant virus nanoparticles are recognized as a platform technology for potential applications in nanomedicine. While non-infectious toward mammals, many plant virus nanoparticles are recognized by the immune system and act as potent adjuvants, both in the classical setting of vaccination and cancer immunotherapy. In the context of cancer immunotherapy, we have demonstrated potent efficacy of plant virus, particularly cowpea mosaic virus (CPMV) when applied intratumorally;CPMV signals through and activates multiple toll-like receptors, which primes a potent innate immune activation leading to reprogramming of the tumor microenvironment from an immunosuppressed to immune-activated state. Data in mouse models of melanoma, colon cancer, ovarian cancer, glioma, and breast cancer demonstrate potent efficacy through priming of the innate immune system leading to adaptive and systemic anti-tumor immunity and most importantly immune memory. Efficacy was also replicated in canine patients with melanoma. Given the promise of the plant virus nanotechnology as an adjuvant for cancer immunotherapy, we also have begun to utilize the technology as a vaccination platform for the generation of COVID-19 vaccine candidates. We formulated multivalent COVID-19 vaccine candidates using plant virus nanoparticles displaying SARS-CoV-2 S protein peptide B cell epitopes. The plant virus nanoparticle confers efficient lymphatic trafficking and targeting of antigen-presenting cells;the adjuvant properties of the nanotechnology lead to robust antibody levels against the target, S protein. While other vaccine candidates have advanced through clinical testing, our approach has unique advantages: The high thermal and pH stability of the plant virus nanotechnology alleviates cold chain requirements;further, the stability of the platform technology enables its integration into vaccine delivery devices such as microneedle patches that can be shipped globally and be self-administered. In this presentation, we will discuss our data on the cancer immunotherapy and highlight the potential to pivot the technology for infectious disease vaccines with unique attributes.

15.
13th IEEE-PES Asia Pacific Power and Energy Engineering Conference (APPEEC) ; 2021.
Article in English | Web of Science | ID: covidwho-1816431

ABSTRACT

Different countries and regions across the world have adopted various responses and containment measures since the early part of 2020 to control the spread of the coronavirus causing Covid-19. These measures have caused significant changes in peoples' mobility, utilization of commercial and industrial facilities, deployment of government resources to provide necessary financial sustenance and support public health. In this study, we have analyzed the impact of these response measures on aggregate electric load in 4 different regions in the US and tried to identify how the load forecasting models may need to be changed post-pandemic. The key findings from our research include (1) the confirmation of a paradigm change in the nature of power demand before and after the pandemic, (2) the emergence of Covid-19 response related factors as predictors of load, and, (3) the reduction in relative importance of traditional load-influencing factors, including temperature, during the pandemic.

16.
European Journal of Molecular and Clinical Medicine ; 9(3):134-138, 2022.
Article in English | EMBASE | ID: covidwho-1756064

ABSTRACT

Aim: To evaluate the mucormycosis cases in post Covid-19 patients. Methods: This cross-sectional observational study was carried out in the Department of Microbiology. Basic microbiological methods such as gram stain and KOH smear were used for the detection of MC in the received clinical specimen and morphology was seen in the microscope. Patients admitted in our hospital with a history of fever, cough, body ache and shortness of breath for 4-5 days with have positive report of nasopharyngeal/ oropharyngeal swab for covid19 RT-PCR were included in the present study. Results: Age, sex and other demography details were collected before sample collection, the average age of the participants was 60.4 ± 7.5 years and the majority of participants were male 75%. Although, 45% participants belong to below 50 year age and 55% of participant belongs to above 50 year age. Out of n=50 specimens, total 9 specimen found positive for fungal smear i.e. n=6 sputum, n=3 nasal swabs and n=0 BAL specimens. Conclusions: The present study concluded that the cases of life threatening MC increase day by day in central India as post complication of covid-19 disease.

17.
Journal of Clinical and Diagnostic Research ; 16(2):OE1-OE3, 2022.
Article in English | Web of Science | ID: covidwho-1753945

ABSTRACT

Coronavirus Disease 2019 (COVID-19), caused by the coronavirus, since its start in Wuhan a city in China has spread like a wild fire and created havoc all over the globe. Initially, the disease was thought to be causing only respiratory complication, but gradually it was found to be causing multiorgan complication. Due to the hypercoagulable property of coronavirus, it has shown neurological, cardiological and endocrine complication. Recently, the effect of the virus on endocrine system has also been noted. Evidence has shown that COVID-19 can hamper the hypothalamo-pituitary axis resulting in altered adrenal response to stress. The immune-mediated damage to the endocrine glands results in subacute thyroiditis. The presence of Angiotensin Converting Enzyme 2 (ACE 2) receptors on various tissues could be the cause of this immune mediated damage. COVID-19 has also precipitated hyperglycaemia and in few cases, uncovered the insulin resistance in previously undiagnosed cases. It is crucial to have knowledge about the impact of endocrine system, as it is the powerhouse of the body.

18.
Indian Journal of Medical Microbiology ; 39:S59-S60, 2021.
Article in English | EMBASE | ID: covidwho-1734471

ABSTRACT

Background:Across the world, health care workers (HCWs’) are at a higher risk of infection by corona virus disease 2019 (COVID-19) due to the nature of their work. HCWs’ include those who are working with patients or their sample as well as those who do not work with patients like office workers. Due to asymptomatic and oligo symptomatic infections, testing only symptomatic individuals can lead to a significant underestimation of the SARS -CoV-2 seroprevalence. This study was to determine presence of anti-SARS-CoV-2 antibodies (IgG) in serum samples of HCWs’ engaged in manage- ment of COVID-19 patients. The prevalence of antibody positivity will make an indicator of exposure in HCWs’. Methods: 500 HCWs’ of the King George's Medical University India were recruited in this prospective observational study. All HCWs, including consultant, resident, nursing staff, lab worker, ward boy, guard and others were enrolled in this study. Participants were grouped depending on the COVID-19 test result. (i) HCWs’ with COVID 19 positive history (ii) HCWs’ with COVID 19 negative history. The period of sampling was first week of September 2020 which coincides with high positivity of the city. Results:The prevalence of COVID-19 was found to be 8% in front-line HCWs’ of our hospital.195 HCW had past history of COVID-19 positivity and 305 were negative for COVID-19. Out of 195,116 HCW were reactive for anti-SARS COV-2 IgG antibody, 5were equivocal and 74were nonreactive for anti -SARS COV-2 IgG antibody. The highest reactivity rates for SARS COV-2 IgG antibody were reported in 26 to35 year’s age of HCW followed by 15-25 years age group of HCW. Out of 116 seropositive HCWs’ 74 were males and 42 were females. Conclusions: We reported 8% COVID-19 seropositivity among HCWs. The prevalence is in concordance with our city infection positivity in month of September i.e around 8-12%.

19.
Indian Journal of Medical Microbiology ; 39:S55, 2021.
Article in English | EMBASE | ID: covidwho-1734456

ABSTRACT

Background:The first case of COVID-19 was reported in India on 30th January 2020 with origin from China (PIB 2020, ‘https:// pib.gov.in/pressreleaseiframepage.aspx?prid=1601095’). As on 6th May 2020 the total cases reported in India are 35,043, with 8,889 recoveries and 1,147 deaths (https://www.mohfw.gov.in/ accessed on 6th may at 12:54 PM). However, the rate of infection is lower as compared to other countries. Since the Covid-19 pandemic started spreading in world outside China including India and large scale testing for Covid-19 became available, all the focus suddenly shifted to Covid-19. Other respiratory viruses, which were in existence for many years and testing and management of these infection was always standard of care, started getting neglected. Hence, we analysed the retrospective laboratory results from cases of acute respiratory infection, tested in the month of February 2020, when Covid-19 cases in India were close to negligible. This is to focus on need of testing for other respiratory viruses along with Covid-19 so that these infections can be managed as per standard protocol and do not get neglected in the wake of pandemic. Methods:The Virus research and diagnostic laboratory at Department of Microbiology, King George’s Medical University (VRDL) start- ed testing for Covid-19 on 3rd February 2020. This laboratory routinely tests all patients presenting as Severe Acute Respiratory Ill- ness (SARI) for 12 respiratory viruses including Influenza (Inf) A (both H1N1 and H3N2) and B, Adenovirus (ADV), Respiratory syntitial virus (RSV), Parainfluenza (Parainf) viruses 1, 2, 3 and 4, Measles virus (MEV), Bocavirus, Human metapneumo virus (HMPV) and Rhi- noviruses (Rhino). All patients presenting as Influenza like illness (ILI) are routinely tested for Influenza A and B viruses. If they test negative, other viruses are tested depending on clinical suspicion. The testing is routinely done as per methods described earlier (Singh A.K., Jain A., Jain B., Singh K.P., Dangi T., Mohan M. Viral aetiology of acute lower respiratory tract illness in hospitalised paedi- atric patients of a tertiary hospital: one year prospective study Indian J Med Microbial. 2014;32:13–18). Results:During February 2020, we tested 316 cases of SARI/ ILI for covid-19. None of them tested positive for Covid-19. Samples from these cases were also tested for other respiratory viruses as mentioned above. Total 10 (3.2%, 8 H1N1 (2.5%) and 2 H3N2 (0.6%)) samples tested positive for Influenza A, 2 each tested positive for Influenza B, HMPV and Adenoviruses. One sample each tested posi- tive for RSV and Rhinoviruses. Total 5 samples tested positive for parainfluenza viruses;3 for parainfluenza 1, and 1 each for parain- fluenza 1 and 4 Conclusions :( table). The positivity for covid-19 in India in pandemic time remains less than 4% (https://www.mohfw.gov.in/ ac- cessed on 06 May 2020, 08:00 IST), while the positivity for rest of the respiratory viruses as shown in present analysis is 7.3%. It is essential to see that infection with other respiratory viruses does not get neglected and add to the Covid-19 misery.

20.
Journal of the Association of Physicians of India ; 69(October):14-17, 2021.
Article in English | GIM | ID: covidwho-1717481

ABSTRACT

Background and Rationale: The government guidance regarding COVID-19 vaccination lists food allergy, drug allergy and history of anaphylaxis as contraindications for receiving vaccination. This study was planned to evaluate such patients listed in the database of an allergy center and who took any COVID-19 vaccine.

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