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1.
Revista Brasileira de Medicina do Trabalho ; 20(1):72-78, 2022.
Article in English | Scopus | ID: covidwho-2026803

ABSTRACT

Introduction: COVID-19 has greatly affected society by limiting the functioning of sectors of the economy and public services. Considering the essential character of many of these services, especially public security, it is necessary to understand how the disease has affected different groups within the population so that public policies for facing this problem can be implemented. Objectives: To identify and describe the profile of military police officers affected by COVID-19. Methods: This is a descriptive observational study with a quantitative approach, based on secondary data. The electronic medical records of 737 military police officers affected by COVID-19 were accessed;sociodemographic, biological, and professional data were collected, as well as data on disease progression. Data were analyzed using Bioestat® software, v5.3. Results: The peak of the COVID-19 contagion curve happened first among military police officers of the state of Alagoas than in the general population, and a positive effect of social distancing was observed in the containment of disease spread. Moreover, specialized operations units had a higher contagion rate in view of the higher level of exposure linked to their work activities. Conclusions: This study described the profile of military police officers affected by COVID-19, which can substantiate the adoption of public policies and new strategies to fight this disease among officers in Alagoas, thus ensuring the continuity of the service provided to society. © 2022 Associacao Nacional de Medicina do Trabalho. All rights reserved.

2.
Journal of Pediatric Hematology/Oncology ; 30:30, 2022.
Article in English | MEDLINE | ID: covidwho-2018334

ABSTRACT

This study aimed to evaluate the risk factors for COVID-19-related death in a large cohort of hospitalized children with hematological disorders. We performed an analysis of all pediatric patients with COVID-19 registered in a Brazilian nationwide surveillance database between February 2020 and May 2021. The primary outcome was time to death, which was evaluated considering discharge as a competitive risk by using the cumulative incidence function. Among 21,591 hospitalized pediatric patients with COVID-19, 596 cases (2.8%) had hematological diseases. Sixty-one children (27.4%) with malignant hematological diseases had a fatal outcome as compared with 4.2% and 7.4% of nonmalignant hematological and nonhematological cohorts, respectively (P<0.0001). Children with hematological diseases had a significant increased hazard of death compared with those without these conditions (hazard ratio [HR],=2.40, 95% confidence interval, 1.98 - 2.91). In multivariable analysis, the factors associated with death were the presence of malignant hematological disease (HR, 2.22, 95% CI 1.47 - 3.36), age >10 years (HR 2.19, 95% CI 1.46 - 3.19), male (HR 1.52, 95% CI 1.02 - 2.27), oxygen saturation <95% (HR 2.02, 95% CI 1.38 - 2.96), and abdominal pain at admission (HR 2.75, 95% CI 1.76 - 4.27). Children with malignant hematological diseases had a higher risk of death compared with those without these disorders.

3.
Environ Manage ; : 1-14, 2022.
Article in English | PubMed | ID: covidwho-2014111

ABSTRACT

In this study, the residual pods of the forest species Erythrina speciosa were carbonized with ZnCl(2) to obtain porous activated carbon and investigated for the adsorptive removal of the drug paracetamol (PCM) from water. The PCM adsorption onto activated carbon is favored at acidic solution pH. The isothermal studies confirmed that increasing the temperature from 298 to 328 K decreased the adsorption capacity from 65 mg g(-1) to 50.4 mg g(-1) (C(0) = 175 mg L(-1)). The Freundlich model showed a better fit of the equilibrium isotherms. Thermodynamic studies confirmed the exothermic nature (ΔH(0) = -39.1066 kJ mol(-1)). Kinetic data indicates that the external mass transfer occurs in the first minutes followed by the surface diffusion, considering that the linear driving force model described the experimental data. The application of the material in the treatment of a simulated effluent with natural conditions was promising, presenting a removal of 76.45%. Therefore, it can be concluded that the application of residual pods of the forest species Erythrina speciosa carbonized with ZnCl(2) is highly efficient in the removal of the drug paracetamol and also in mixtures containing other pharmaceutical substances.

4.
JAMA Network Open ; 5(9):e2230637, 2022.
Article in English | MEDLINE | ID: covidwho-2013248

ABSTRACT

Importance: Determining the characteristics, type, and severity of olfactory dysfunction in patients with long COVID is important for the prognosis and potential treatment of the affected population. Objective: To describe the sociodemographic and clinical features of patients with long COVID who develop persistent olfactory dysfunction. Design, Setting, and Participants: This cross-sectional study, conducted at a rehabilitation center at a public university in the Amazon region of Brazil between September 9, 2020, and October 20, 2021, comprised 219 patients with long COVID and self-reported neurologic symptoms. Of these 219 patients, 139 received a diagnosis of chronic olfactory dysfunction, as confirmed by the Connecticut Chemosensory Clinical Research Center (CCCRC) test. Exposure: Clinical diagnosis of long COVID. Main Outcomes and Measures: Electronic case report forms were prepared for the collection of sociodemographic and clinical data. Patients' sense of smell was evaluated via a CCCRC test, and the association of olfactory dysfunction with aspects of daily life was recorded using a questionnaire. Results: Of the 219 patients included in the study, 164 (74.9%) were women, 194 (88.6%) were between 18 and 59 years of age (mean [SD] age, 43.2 [12.9] years), 206 (94.1%) had more than 9 years of education, and 115 (52.5%) had a monthly income of up to US $192.00. In the study group, 139 patients (63.5%) had some degree of olfactory dysfunction, whereas 80 patients (36.5%) had normosmia. Patients with olfactory dysfunction had a significantly longer duration of long COVID symptoms than those in the normosmia group (mean [SD], 242.7 [101.9] vs 221.0 [97.5] days;P = .01). Among patients with anosmia, there was a significant association between olfactory dysfunction and daily activities, especially in terms of impairment in hazard detection (21 of 31 patients [67.7%]), personal hygiene (21 of 31 patients [67.7%]), and food intake (21 of 31 patients [67.7%]). Univariable logistic regression analyses found that ageusia symptoms were associated with the occurrence of olfactory dysfunction (odds ratio [OR], 11.14 [95% CI, 4.76-26.07];P < .001), whereas headache (OR, 0.41 [95% CI, 0.22-0.76];P < .001) and sleep disorders (OR, 0.48 [95% CI, 0.26-0.92];P = .02) showed an inverse association with the occurrence of olfactory dysfunction. Conclusions and Relevance: Olfactory dysfunction is one of the most important long-term neurologic symptoms of COVID-19, with the highest prevalence seen among women, adults, and outpatients. Patients with olfactory dysfunction may experience persistent severe hyposmia or anosmia more than 1 year from the onset of symptoms, suggesting the possibility of the condition becoming a permanent sequela.

5.
Archives of Veterinary Science ; 27(2):85-97, 2022.
Article in Portuguese | CAB Abstracts | ID: covidwho-2012568

ABSTRACT

The Distance Learning method (e-learning) was adopted by a huge part of Higher Education Institutions as an alternative to academical paralisations due to COVID- 19 pandemic. This scenario brings new challenges to the graduation courses, specially those with higher practical content, including veterinary medicine courses. This study aimed to assess the graduation students' perspectives about the e-Learning for the discipline of Veterinary Semiology, considering their learning processes and expactations. Three anonimous formularies were applied to obtain informations about students' prospects and their access to resources for the remote learning platforms. Also, the preferences over the testing methods and the efficacy of learning were evaluated. Furthermore, it was possible to understand the opinion of these students after the conclusion of the discipline, and comprise general health aspects of these groups during COVID pandemic. Through direct answers brought by students' conceptions, this study elucidated positive and negative aspects over the remote learning methods, and helped on the discussion about practical skills education on remote mode. The data obtained on this study aims to help on didactic pratices in veterinary medicine subjects, as well as adjust both training and adhesion to new digital tools in a complementary way to presential education.

6.
Annals of the Rheumatic Diseases ; 81:163-164, 2022.
Article in English | EMBASE | ID: covidwho-2008909

ABSTRACT

Background: Some factors associated with severe COVID-19 outcomes have been identifed in patients with psoriasis (PsO) and infammatory/autoimmune rheumatic diseases, namely older age, male sex, comorbidity burden, higher disease activity, and certain medications such as rituximab. However, information about specifcities of patients with PsO, psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), including disease modifying anti-rheumatic drugs (DMARDs) specifcally licensed for these conditions, such as IL-17 inhibitors (IL-17i), IL-23/IL-12 + 23 inhibitors (IL-23/IL-12 + 23i), and apremilast, is lacking. Objectives: To determine characteristics associated with severe COVID-19 outcomes in people with PsO, PsA and axSpA. Methods: This study was a pooled analysis of data from two physician-reported registries: the Psoriasis Patient Registry for Outcomes, Therapy and Epidemiology of COVID-19 Infection (PsoProtect), comprising patients with PsO/PsA, and the COVID-19 Global Rheumatology Alliance (GRA) registry, comprising patients with PsA/axSpA. Data from the beginning of the pandemic up to 25 October, 2021 were included. An ordinal severity outcome was defned as: 1) not hospitalised, 2) hospitalised without death, and 3) death. A multivariable ordinal logistic regression model was constructed to assess the relationship between COVID-19 severity and demographic characteristics (age, sex, time period of infection), comorbidities (hypertension, other cardiovascular disease [CVD], chronic obstructive lung disease [COPD], asthma, other chronic lung disease, chronic kidney disease, cancer, smoking, obesity, diabetes mellitus [DM]), rheumatic/skin disease (PsO, PsA, axSpA), physician-reported disease activity, and medication exposure (methotrexate, lefunomide, sulfasalazine, TNFi, IL17i, IL-23/IL-12 + 23i, Janus kinase inhibitors (JAKi), apremilast, glucocorticoids [GC] and NSAIDs). Age-adjustment was performed employing four-knot restricted cubic splines. Country-adjustment was performed using random effects. Results: A total of 5008 individuals with PsO (n=921), PsA (n=2263) and axSpA (n=1824) were included. Mean age was 50 years (SD 13.5) and 51.8% were male. Hospitalisation (without death) was observed in 14.6% of cases and 1.8% died. In the multivariable model, the following variables were associated with severe COVID-19 outcomes: older age (Figure 1), male sex (OR 1.53, 95%CI 1.29-1.82), CVD (hypertension alone: 1.26, 1.02-1.56;other CVD alone: 1.89, 1.22-2.94;vs no hypertension and no other CVD), COPD or asthma (1.75, 1.32-2.32), other lung disease (2.56, 1.66-3.97), chronic kidney disease (2.32, 1.50-3.59), obesity and DM (obesity alone: 1.36, 1.07-1.71;DM alone: 1.85, 1.39-2.47;obesity and DM: 1.89, 1.34-2.67;vs no obesity and no DM), higher disease activity and GC intake (remission/low disease activity and GC intake: 1.96, 1.36-2.82;moderate/severe disease activity and no GC intake: 1.35, 1.05-1.72;moderate/severe disease activity and GC intake 2.30, 1.41-3.74;vs remission/low disease activity and no GC intake). Conversely, the following variables were associated with less severe COVID-19 outcomes: time period after 15 June 2020 (16 June 2020-31 December 2020: 0.42, 0.34-0.51;1 January 2021 onwards: 0.52, 0.41-0.67;vs time period until 15 June 2020), a diagnosis of PsO (without arthritis) (0.49, 0.37-0.65;vs PsA), and exposure to TNFi (0.58, 0.45-0.75;vs no DMARDs), IL17i (0.63, 0.45-0.88;vs no DMARDs), IL-23/IL-12 + 23i (0.68, 0.46-0.997;vs no DMARDs) and NSAIDs (0.77, 0.60-0.98;vs no NSAIDs). Conclusion: More severe COVID-19 outcomes in PsO, PsA and axSpA are largely driven by demographic factors (age, sex), comorbidities, and active disease. None of the DMARDs typically used in PsO, PsA and axSpA, were associated with severe COVID-19 outcomes, including IL-17i, IL-23/IL-12 + 23i, JAKi and apremilast.

7.
Giovanetti, M.; Slavov, S. N.; Fonseca, V.; Wilkinson, E.; Tegally, H.; Patané, J. S. L.; Viala, V. L.; San, E. J.; Rodrigues, E. S.; Santos, E. V.; Aburjaile, F.; Xavier, J.; Fritsch, H.; Adelino, T. E. R.; Pereira, F.; Leal, A.; Iani, F. C. M.; de Carvalho Pereira, G.; Vazquez, C.; Sanabria, G. M. E.; Oliveira, E. C.; Demarchi, L.; Croda, J.; Dos Santos Bezerra, R.; Paola Oliveira de Lima, L.; Martins, A. J.; Renata Dos Santos Barros, C.; Marqueze, E. C.; de Souza Todao Bernardino, J.; Moretti, D. B.; Brassaloti, R. A.; de Lello Rocha Campos Cassano, R.; Mariani, Pdsc, Kitajima, J. P.; Santos, B.; Proto-Siqueira, R.; Cantarelli, V. V.; Tosta, S.; Nardy, V. B.; Reboredo de Oliveira da Silva, L.; Gómez, M. K. A.; Lima, J. G.; Ribeiro, A. A.; Guimarães, N. R.; Watanabe, L. T.; Barbosa Da Silva, L.; da Silva Ferreira, R.; da Penha, M. P. F.; Ortega, M. J.; de la Fuente, A. G.; Villalba, S.; Torales, J.; Gamarra, M. L.; Aquino, C.; Figueredo, G. P. M.; Fava, W. S.; Motta-Castro, A. R. C.; Venturini, J.; do Vale Leone de Oliveira, S. M.; Gonçalves, C. C. M.; do Carmo Debur Rossa, M.; Becker, G. N.; Giacomini, M. P.; Marques, N. Q.; Riediger, I. N.; Raboni, S.; Mattoso, G.; Cataneo, A. D.; Zanluca, C.; Duarte Dos Santos, C. N.; Assato, P. A.; Allan da Silva da Costa, F.; Poleti, M. D.; Lesbon, J. C. C.; Mattos, E. C.; Banho, C. A.; Sacchetto, L.; Moraes, M. M.; Grotto, R. M. T.; Souza-Neto, J. A.; Nogueira, M. L.; Fukumasu, H.; Coutinho, L. L.; Calado, R. T.; Neto, R. M.; Bispo de Filippis, A. M.; Venancio da Cunha, R.; Freitas, C.; Peterka, C. R. L.; de Fátima Rangel Fernandes, C.; Navegantes, W.; do Carmo Said, R. F.; Campelo de, A. E. Melo C. F.; Almiron, M.; Lourenço, J.; de Oliveira, T.; Holmes, E. C.; Haddad, R.; Sampaio, S. C.; Elias, M. C.; Kashima, S.; Junior de Alcantara, L. C.; Covas, D. T..
Nat Microbiol ; 2022.
Article in English | PubMed | ID: covidwho-1991610

ABSTRACT

The high numbers of COVID-19 cases and deaths in Brazil have made Latin America an epicentre of the pandemic. SARS-CoV-2 established sustained transmission in Brazil early in the pandemic, but important gaps remain in our understanding of virus transmission dynamics at a national scale. We use 17,135 near-complete genomes sampled from 27 Brazilian states and bordering country Paraguay. From March to November 2020, we detected co-circulation of multiple viral lineages that were linked to multiple importations (predominantly from Europe). After November 2020, we detected large, local transmission clusters within the country. In the absence of effective restriction measures, the epidemic progressed, and in January 2021 there was emergence and onward spread, both within and abroad, of variants of concern and variants under monitoring, including Gamma (P.1) and Zeta (P.2). We also characterized a genomic overview of the epidemic in Paraguay and detected evidence of importation of SARS-CoV-2 ancestor lineages and variants of concern from Brazil. Our findings show that genomic surveillance in Brazil enabled assessment of the real-time spread of emerging SARS-CoV-2 variants.

9.
MEDICINA BALEAR ; 37(4):39-46, 2022.
Article in English | Web of Science | ID: covidwho-1968982

ABSTRACT

Objectives: During lockdown by COVID-19, some individuals engaged in behaviours generating a greater sense of positivity and control. The objective was to identify relationships between affect, coping strategies, and resilience with task management, distress caused by lockdown, and difficulty observing public health restrictions. Methods: A cross-sectional observational study (May 2020) was carried out in the Complutense University of Madrid. The sample consisted of 50 first-year Health Sciences students, wich were assessed during lockdown by COVID19. The followins scales were used: the Positive and Negative Affect Schedule (PANAS), the Coping Orientation to Problems Experienced inventory, the ConnorDavidson Resilience Scale, and the Escala de Gestion de Actividades en Situacion de Confinamiento (Activity Management during Lockdown Scale). Results: Thirty-five students (70%) displayed a score of (3)6 on the scale measuring the distress caused by the public health restrictions. Associations with r values of =0.5 were: distress caused by the pandemic and positive affect (r=0.512);seeking new hobbies and seeking social support (r=0.567);seeking new hobbies and humour (r=0.56);reading and active problem-focused coping (r=0.5). Conclusions: Positive affect is influenced by behaviours linked to helping neighbours. Strategies allowing subjects to occupy their time more constructively were: active problem-focused coping, seeking psychosocial support, and acceptance and personal growth. The factors related to negative affect were alcohol consumption and/or drug use, humour.

11.
Archives of Veterinary Science ; 27(2):85-97, 2022.
Article in English, Portuguese | Scopus | ID: covidwho-1964355

ABSTRACT

The Distance Learning method (e-learning) was adopted by a huge part of Higher Education Institutions as an alternative to academical paralisations due to COVID-19 pandemic. This scenario brings new challenges to the graduation courses, specially those with higher practical content, including veterinary medicine courses. This study aimed to assess the graduation students' perspectives about the e-Learning for the discipline of Veterinary Semiology, considering their learning processes and expactations. Three anonimous formularies were applied to obtain informations about students' prospects and their access to resources for the remote learning platforms. Also, the preferences over the testing methods and the efficacy of learning were evaluated. Furthermore, it was possible to understand the opinion of these students after the conclusion of the discipline, and comprise general health aspects of these groups during COVID pandemic. Through direct answers brought by students' conceptions, this study elucidated positive and negative aspects over the remote learning methods, and helped on the discussion about practical skills education on remote mode. The data obtained on this study aims to help on didactic pratices in veterinary medicine subjects, as well as adjust both training and adhesion to new digital tools in a complementary way to presential education. © 2022. All Rights Reserved.

12.
Marketing & Tourism Review ; 7(1), 2022.
Article in English | CAB Abstracts | ID: covidwho-1965042

ABSTRACT

The COVID-19 pandemic brought the production process to a halt in the tourist chain, directly impacting the economic sphere and marketing communication between organizations in the segment and their interested public. The present work aims to identify whether the communication through the Instagram posts of the multinational hotel chain Accor was adapted to the COVID-19 pandemic scenario between December 2019 and June 2020 and the followers' level of engagement in its digital profile. The more-than-human netnography proposed by Lugosi & Quinton (2018) was adopted as a methodological approach, having as object of analysis the posts of the profile @all_latam (Accor America Latina) on Instagram and the behavior of the followers. We identified a follower appreciation regarding COVID-19 material. Therefore, hotel companies should produce crisis content related to increasing engagement on Social media posts.

13.
Revista Paulista de Pediatria ; 40, 2022.
Article in English | EMBASE | ID: covidwho-1957119

ABSTRACT

Objective: The aim of this study was to evaluate the coronavirus disease 2019 (COVID-19) cutaneous manifestations described in pediatric patients and discuss their relevance for early diagnosis. Data source: The study consisted of a systematic review of original articles indexed in PubMed and Embase databases, as well as gray literature articles found through Google Scholar. A search strategy, based on PICO (Patient, Intervention, Comparison, Outcome) Tool, with the terms "child," "infant," "childhood," "adolescents," "teenagers," "COVID-19," "SARS-CoV-2," and "skin manifestations," was performed to optimize the findings. The study did not restrict any article regarding language. Data synthesis: Out of the 310 articles that initially met the inclusion criteria, 35 were selected for review, totalizing 369 patients. The most common COVID-19 cutaneous manifestations in children and adolescents were Chilblain-like lesions, presented in 67.5% of the cases, followed by erythema multiforme-like (31.7%) and varicella-like lesions (0.8%). The Chilblain-like lesions appeared 7.6 days (95%CI 7.4-7.8) after the viral infection and lasted for 17.5 days (95%CI 16.5-18.5), erythema multiformelike lesions appeared in 9.5 days (95%CI 9-10) and lasted for 10.3 days (95%CI 9.1-11.5), and varicella-like lesions appeared in 12.3 days (95%CI 4-20.6) and lasted for 7 days. Conclusions: Knowledge of the different skin manifestations in children and adolescents with COVID-19 is essential for an early diagnosis and, consequently, the possibility of promptly care adoption as well as to interrupt the new coronavirus transmission chains in the current pandemic context.

15.
Journal of Porphyrins and Phthalocyanines ; 2022.
Article in English | Scopus | ID: covidwho-1950284

ABSTRACT

Photodynamic therapy (PDT) is a multi-component therapy which relies on the delivery of a photosensitizer drug and light in the presence of oxygen to mediate a therapeutic anti-cancer or anti-microbial effect. As a multi-component therapy, a multidisciplinary research approach is required to achieve success with the application of PDT. The POLYTHEA network, a project funded under the Marie Skołodowska-Curie Actions (MSCA) of Horizon 2020 (H2020) program, provided an opportunity to build a collaboration of laboratories across Europe with the necessary expertise required for the different facets of PDT. In the process, ten early-stage researchers (ESRs) were trained with the aim of achieving European Joint Doctorate degrees. The project managed to fulfill goals of collaborative research, transferable skills training, and public outreach, despite the occurrence of the Covid-19 pandemic. The benefits of this type of MSCA funding for the main participants, students and supervisors, are highly relevant to their career but are not free from challenges. With the POLYTHEA project soon ending, a reflection of the most positive and negative aspects of the project from its inception is opportune. © 2022 World Scientific Publishing Co. Pte Ltd. All rights reserved.

16.
Sleep Science ; 15:13-14, 2022.
Article in English | EMBASE | ID: covidwho-1935280

ABSTRACT

Introduction: Changes in sleep patterns have been documented worldwide since the onset of the Covid-19 pandemic. Among people infected by the new coronavirus, sleep disturbances were detected even after the acute phase of the disease, becoming a prevalent problem in Post-Covid Syndrome. Objective: The present study evaluated the quality of sleep (QS) and prevalence of insomnia among Covid-19 survivors undergoing a physical rehabilitation program. Methods: This is a descriptive, observational and cross-sectional study using the Pittsburgh Sleep Quality Index (PSQI);Insomnia Severity Index (ISI);and the question “whether sleep was better before Covid-19”;approved by the research ethics committee. Results: Fortytwo patients were evaluated between May and August 2021, referred to the Post-Covid Rehabilitation section, aged 45.6±14.5 years, 23 women (55%), BMI of 29.8±5.5 kg/ m2, median Covid diagnosis time of 96 days (22-485) and 60% with mild functional limitation (grade II). Twenty-five patients were hospitalized (59%) for an average of 15 days (1-90), 12 in intensive care (2 to 30 days) and 20 in the ward (1 to 60 days). Overall, poor QS and sleep disturbance occurred for 34 patients (81%), with 19 (56%) reporting sleeping well before Covid-19. Only eight patients (19%) had good QS. Twenty-two patients had a positive insomnia score, at the lower limit (33%), moderate (17%) or severe (2%);of which nine said reported having good quality sleep before Covid. Prevalence of Insomnia was 25% among wards hospitalization and 33% of critical cases. QS was compromised among 95% of patients hospitalized in the ward and for 66% of those who were in intensive care. Fatigue was the most prevalent symptom among other sleep disruptors. Conclusion: QS was impaired for most patients, with insomnia for more than half, for which sleep also became poor after Covid-19. High prevalence of fatigue, obesity and repercussions of illness should be considered. In view of the negative impact and bidirectional relationship of impaired sleep and physical and mental recovery, a more accurate investigation of sleep, as well therapies for its interfering factors, should be incorporated into the rehabilitation program.

17.
Sleep Science ; 15:38, 2022.
Article in English | EMBASE | ID: covidwho-1935243

ABSTRACT

Introduction: Sleep is considered a cyclical physiological state due to the alternation between sleep and wakefulness that occur in most living beings. It is characterized by five fundamental stages and the total or partial absence of quality nighttime sleep can cause sleep and wake disorders, which are related to damage to the health of the population. Relating the theme to medical students, it is known that this population experiences, since college, the reality of a few hours to sleep and rest. Also, by associating this issue in the current context of COVID-19, it is possible that the quality of sleep in this population has changed. Objective: To identify the prevalence of the occurrence of Sleep Disorders and associated factors among medical students from a higher education institution in the forest region of Minas Gerais. Methods: The research, with a cross-sectional design, was conducted online through a semi-structured questionnaire with social, personal, demographic variables and also using the Epworth Sleepiness Scale and the Pittsburg Sleep Quality Index. Results: Of the total of 340 academics invited to participate in the study, 63.8% participated in the survey. 41% of the participants stated that they had a sleep duration per night of less than six hours and in relation to the usual sleep efficiency, 50.7% certified that they have an efficacy of less than 84%, evidencing a high frequency of sleep disorders (94, 9%). Also regarding the analysis of the Pittsburg Scale for Assessment of Sleep Quality, comparing cycles (basic, clinical and internship), 14% of students in the basic cycle need to use medication to sleep 3 or more times a week, as opposed to 7% denounced by the analysis of both the clinical cycle and the internship. About 40% of basic cycle students, 22% of clinical cycle students and 4% of boarding students reported having daytime dysfunction 5 to 6 days a week, such as difficulty staying awake and focused on their daily activities, in as a result of disturbed nights of sleep. As for the Epworth sleepiness scale, only 31.7% of the sample had normal sleep and in 44% of students an abnormal (pathological) sleepiness was identified. Conclusion: It is concluded that the perception of poor sleep quality was high for all years of the medical graduation course. Regarding the comparison of course phases, students in the early years (basic cycle group) reported worse sleep quality and greater daytime dysfunction.

18.
Sleep Science ; 15:67, 2022.
Article in English | EMBASE | ID: covidwho-1935147

ABSTRACT

Introduction: Obstructive sleep apnea and hypopnea syndrome (OSAHS) is characterized by pauses in breathing during sleep, due to multiple collapses and/or narrowing of the upper airway, causing a drop in blood oxygen saturation and sleep fragmentation. Obesity, male gender, craniofacial abnormalities, tonsil hypertrophy, nasal obstruction, endocrine abnormalities, and family history are predictive factors for OSAHS. Objective: The aim of the study was to investigate OSAHS through home polysomnography during the COVID-19 pandemic. Methods: Data were collected between March 16, 2020, and June 25, 2021 in the city of Surubim-PE, totaling 191 subjects. The Apnea link Air portable polysomnographic device was used. With the following channels: respiratory effort, pulse, oxygen saturation, nasal flow and snoring. Data were analyzed using IBM SPSS 28.0 software. Results: The apnea and hypopnea index (AHI) was considered: Normal in 33 women (17.0%;2.1+1.3) and 41 men (21.2%;2.5+1.2);Mild on 18 women (9.3%;9.4+3.3) and 39 men (20.2%;8.8+3.1);Moderate in 5 women (2.5%;19.5+4.5) and 27 men (13.9%;21.4+4.7);and Severe in 8 women (4.1%;52.5+14.4) and 22 men (11.3%;51.5+17.4). The oxygen desaturation index (IDO) was, 32 women (16.5%;2.1 + 1.7) and 40 men (20.7%;2.6 + 1.1) were classified as normal;Mild in 18 women (9.3%;9.6 + 2.9) and 30 men (15.5%;8.8 + 2.8);Moderate in 6 women (3.1%;20.9 + 5.2) and 27 men (13.9%;21.4 + 4.4);and Severe in 7 women (3.6%;53.2 + 11.5) and 22 men (11.4%;50.2 + 17.3). A positive correlation was observed both between BMI and the apnea-hypopnea index (AHI) (r=0.527;p=<0.01), as well as the BMI and oxygen desaturation index (ODI) (r=0.516;p=<0.01). There is an effect of gender (p<0.008) and age (p<0.001) on the AHI, but there is no interaction between the variables gender and age (p=0.936) A similar result was observed for the ODI, in which there is an effect of gender (p<0.009) and age (p<0.001), but not in the interaction between the two variables (p=0.948) BMI had an effect on the AHI (p<0.001) and ODI (p<0.001) but not in the interaction between BMI and gender (p=0.250 and p=0.223 respectively). Conclusion: High BMI implies higher values of AHI and ODI in the study population. Although there is an effect of gender and age on the AHI and ODI, an interaction between these two variables is not maintained when analyzed.

19.
NUTRICION CLINICA Y DIETETICA HOSPITALARIA ; 42(2):80-88, 2022.
Article in Portuguese | Web of Science | ID: covidwho-1939426

ABSTRACT

Introduction: At the end of 2019 in the city of Wuhan, China, the first cases of respiratory syndrome caused by coronavirus 2019 disease (COVID-19) were described. Obesity or malnutrition, associated with comorbidities such as hypertension and diabetes can significantly increase the risk of hospitalization and death in these patients. Goals: to evaluate the relationship between nutritional status and the presence of comorbidities with the length of hospital stay, biochemical parameters and clinical outcome of patients with COVID-19. Materials and methods: a retrospective study that is part of a multicenter project from the Federal University of Alagoas and with a collaborating center at the Federal University of Pernambuco, carried out from the collection of data from medical records of patients hospitalized with COVID-19, who were hospitalized in a hospital in Pernambuco and one in Alagoas from March to December 2020. Data were analyzed using the Statistical Package for Social Sciences (SPSS) software, version 20.0, and the significance level adopted was 5%. Results: The sample consisted of 97 patients, mostly elderly, where 66.9% of patients had hypertension and 41.2% diabetes. The group with a previous diagnosis of diabetes had a longer hospital stay when compared to the group without this comorbidity (p = 0.050). The mean BMI was 26.2 +/- 4.85 kg/m(2), where most patients were overweight (46.2%) and 8.8% were underweight. In the analysis of the association between the study variables and the clinical outcome, it was observed that age and the diagnosis of diabetes were associated with the outcome of death. Conclusion: Worse clinical prognosis, increased length of hospital stay and higher risk of mortality were observed among diabetic and older patients.

20.
Proceedings of the European Conference on Agricultural Engineering, AgEng2021, Evora, Portugal ; 2021.
Article in English | CAB Abstracts | ID: covidwho-1918779

ABSTRACT

Sustainable agriculture is urgently needed to promote conservation and sustainable resources use in an equitable manner through integrated management of land, water, energy and biodiversity. In this way, education in agriculture emerges as a crucial tool for preparing agricultural technicians, researchers and farmers for productive contributions. Higher education institutions arise with an important mission of education in the context of social transformation and to integrate sustainable development into the educational system as a scientific subject. The aim of this study was to identify the training and learning needs to be included in a MSc program in sustainable agriculture. It was based on a questionnaire prepared and distributed to academics' experts in Agrarian Sciences in Greece, Italy and Portugal. Technologies, legislation, management and business, local community leadership and marketing were the training needs considered very important expertise's in sustainable agriculture. Traditional face-to-face learning, experienced farmers as mentors and knowledge sharing mechanisms were rated as very applicable and important. Due to COVID-19 pandemic, online learning methods, which were not considered suitable for a MSc program in sustainable agriculture, became important by providing online education. Information and communication technology and technological tools showed to be important skills for sustainable agricultural practices to effectively implement online learning and to improve the efficient access, exposure and use of up-to-date information of the agricultural sector and awareness of sustainable agricultural practices.

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