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1.
J Med Virol ; 2021 Nov 05.
Article in English | MEDLINE | ID: covidwho-1718379

ABSTRACT

Despite extensive vaccination, the quantity of patients infected with the SARS-CoV-2 virus and its variants continues to grow worldwide. Treating patients with a severe course of COVID-19 is a difficult challenge. One of the generally accepted and specific therapy methods is the use of plasma rich in anti-SARS-CoV-2 antibodies. On the other hand, assessing the antibodies level depending on the time after infection allows for vaccine-decision. The study marked the level of anti-SARS-CoV-2 IgG antibodies in 351 COVID-19 convalescent residents of one geographical region in Poland. The study group included blood donors. The studies were cross-sectional and extended to a questionnaire to determine infection severity. These data were compiled statistically. The study considered epidemiological factors, the time from the end of the infection, and infection severity. The fastest increase of the antibodies level was observed up to 59 days after COVID-19, and it was statistically significantly higher among men. Higher levels of antibodies were found among people above the average age in both men and women. There was an increase in the level of antibodies since the onset of the disease in men, while in women, it decreased. The antibodies level was also found to depend on the severity of the course of COVID-19 infection. The optimal group of plasma donors in the studied geographical region is men and women above 39 years old. after a more severe infection. The titer of antibodies increases with time from the disease.

3.
Med Pr ; 72(3): 327-334, 2021 Jun 30.
Article in Polish | MEDLINE | ID: covidwho-1413301

ABSTRACT

Generally, COVID-19 is an acute contagious disease caused by the SARS­CoV-2 virus. The main route of human-to-human transmission is through contact with infectious secretions from the respiratory tract. Clinical manifestations vary from mild non-specific symptoms to life-threatening conditions. Since WHO declared COVID-19 a pandemic in March 2020, it has affected many medical, legal, social and economic aspects of everyday life in countries around the world. In this article, the authors present a summary of recommendations for taking care of otorhinolaryngology patients in outpatient settings and the legal basis referring to a risk of infection in doctor's office. In the selection of articles, the authors used English- and Polish-language online medical databases, typing the following keywords: SARS­CoV-2, COVID-19, otolaryngology, endoscopy, personal protective equipment, and legal responsibility of the physician. The mucosa of the upper respiratory tract is a potential site of virus replication. The specificity of an ear, nose and throat (ENT) examination and a direct patient-doctor contact favor the transmission of the infection. The authors discussed the elements of self-protection of medical personnel and the legal aspects a risk of the patient contracting the infection in the otolaryngology office. In the case of a direct contact with the patient, the following medical personal protective equipment is required: a cap, a mask with an FFP-2 filter, goggles, an apron and gloves. If, during the visit, exposure to secretions or aerosol from the respiratory tract is expected, the personnel should additionally wear a visor and a waterproof apron. The patient's visit in the clinic should be preceded by telemedicine consultation. Patients should be screened prior to having a direct contact with a physician, using a short patient questionnaire. The questionnaire may consist of simple questions about the characteristic symptoms of the SARS­CoV-2 infection and exposure to a sick person in the past 14 days. The question of staying in the areas of a high infection risk appears of little importance in view of the whole of Poland being perceived as constituting such an area. Due to the spread of the SARS­CoV-2 virus, new procedures for providing medical services have been introduced. In the case of claims on the part of the patient, the only protection the medical personnel or facility can provide is confirmation of scrupulous compliance with medical procedures . Med Pr. 2021;72(3):327-34.


Subject(s)
COVID-19/prevention & control , Infection Control/standards , Otolaryngology/standards , COVID-19/transmission , Health Personnel , Humans , Infection Control/legislation & jurisprudence , Otolaryngology/legislation & jurisprudence , Personal Protective Equipment
4.
Med Pr ; 72(3): 321-325, 2021 Jun 30.
Article in Polish | MEDLINE | ID: covidwho-1413233

ABSTRACT

In 2019, COVID-19, the disease caused by the SARS-CoV-2 virus, evolved into a pandemic which is still going on. The basic clinical symptoms of the SARS-CoV-2 infection are: fever, dry cough, fatigue, muscle pain, respiratory problems, and the loss of smell or taste. Other symptoms, including those related to hearing and balance organs (hearing loss, tinnitus, dizziness), are reported less frequently by patients. They are especially rarely reported as the first symptoms of this infection. In order to answer the question of whether SARS-CoV-2 can cause hearing and balance damage, the authors reviewed the literature sources from 2019-2020 included in EMBASE and PubMed, entering the following words: "hearing loss," "COVID-19," "coronavirus," "sensorineural hearing loss," "vertigo," and "dizziness." Ultimately, 9 studies on the possible relationship between hearing impairment and SARS-CoV-2, and 4 studies on the possible relationship between damage to the balance and SARS-CoV-2, were qualified for the study. The results of the analysis suggest a possible relationship between COVID-19 and hearing loss, with no evidence of a similar relationship between this virus and the balance system. The possible existence of such a relationship should be especially remembered by hospital emergency room doctors, otolaryngologists and audiologists, especially as regards the possibility of a sudden sensironeural hearing loss as the first symptom of COVID-19. This also applies to doctors of other specialties. The authors indicate the need for further, intensive and multifaceted research on this issue. Med Pr. 2021;72(3):321-5.


Subject(s)
COVID-19/complications , Hearing Disorders/etiology , Hearing , Postural Balance , Vestibular Diseases/etiology , Adult , COVID-19/epidemiology , COVID-19/physiopathology , Female , Hearing Loss/etiology , Humans , Male , Middle Aged , Tinnitus/etiology , Vertigo/etiology , Young Adult
6.
Am J Otolaryngol ; 42(5): 103131, 2021.
Article in English | MEDLINE | ID: covidwho-1275107
7.
Environ Res ; 198: 111229, 2021 07.
Article in English | MEDLINE | ID: covidwho-1209551

ABSTRACT

We aimed to develop a model to quantitatively assess the potential effectiveness of face shield (visor) in reducing airborne transmission risk of the novel coronavirus SARS-CoV-2 during the current COVID-19 pandemic using the computational fluid dynamics (CFD) method. The studies with and without face shield in both an infected and healthy person have been considered in indoor environment simulation. In addition to the influence of the face shield and the synchronization of the breathing process while using the device, we also simulated the effect of small air movements on the SARS-CoV-2 infection rate (outdoor environment simulation). The contact with infectious particles in the case without a face shield was 12-20 s (s), in the presence of at least one person who was positive for SARS-CoV-2. If the infected person wore a face shield, no contact with contaminated air was observed during the entire simulation time (80 s). The time of contact with contaminated air (infection time) decreases to about 11 s when the surrounding air is still and begins to move at a low speed. Qualitative differences between simulations performed on the patients with and without the face shield are clearly visible. The maximum prevention of contagion is probably a consequence of wearing a face shield by an infected person. Our results suggest that it is possible to determine contact with air contaminated by SARS-CoV-2 using the CFD method under realistic conditions for virtually any situation and configuration. The proposed method is probably the fastest and most reliable among those based on CFD-based techniques.


Subject(s)
COVID-19 , SARS-CoV-2 , Air Movements , Humans , Pandemics , Tomography
8.
Med Pr ; 72(3): 321-325, 2021 Jun 30.
Article in Polish | MEDLINE | ID: covidwho-1175785

ABSTRACT

In 2019, COVID-19, the disease caused by the SARS-CoV-2 virus, evolved into a pandemic which is still going on. The basic clinical symptoms of the SARS-CoV-2 infection are: fever, dry cough, fatigue, muscle pain, respiratory problems, and the loss of smell or taste. Other symptoms, including those related to hearing and balance organs (hearing loss, tinnitus, dizziness), are reported less frequently by patients. They are especially rarely reported as the first symptoms of this infection. In order to answer the question of whether SARS-CoV-2 can cause hearing and balance damage, the authors reviewed the literature sources from 2019-2020 included in EMBASE and PubMed, entering the following words: "hearing loss," "COVID-19," "coronavirus," "sensorineural hearing loss," "vertigo," and "dizziness." Ultimately, 9 studies on the possible relationship between hearing impairment and SARS-CoV-2, and 4 studies on the possible relationship between damage to the balance and SARS-CoV-2, were qualified for the study. The results of the analysis suggest a possible relationship between COVID-19 and hearing loss, with no evidence of a similar relationship between this virus and the balance system. The possible existence of such a relationship should be especially remembered by hospital emergency room doctors, otolaryngologists and audiologists, especially as regards the possibility of a sudden sensironeural hearing loss as the first symptom of COVID-19. This also applies to doctors of other specialties. The authors indicate the need for further, intensive and multifaceted research on this issue. Med Pr. 2021;72(3):321-5.


Subject(s)
COVID-19/complications , Hearing Disorders/etiology , Hearing , Postural Balance , Vestibular Diseases/etiology , Adult , COVID-19/epidemiology , COVID-19/physiopathology , Female , Hearing Loss/etiology , Humans , Male , Middle Aged , Tinnitus/etiology , Vertigo/etiology , Young Adult
9.
Med Pr ; 72(3): 327-334, 2021 Jun 30.
Article in Polish | MEDLINE | ID: covidwho-1158453

ABSTRACT

Generally, COVID-19 is an acute contagious disease caused by the SARS­CoV-2 virus. The main route of human-to-human transmission is through contact with infectious secretions from the respiratory tract. Clinical manifestations vary from mild non-specific symptoms to life-threatening conditions. Since WHO declared COVID-19 a pandemic in March 2020, it has affected many medical, legal, social and economic aspects of everyday life in countries around the world. In this article, the authors present a summary of recommendations for taking care of otorhinolaryngology patients in outpatient settings and the legal basis referring to a risk of infection in doctor's office. In the selection of articles, the authors used English- and Polish-language online medical databases, typing the following keywords: SARS­CoV-2, COVID-19, otolaryngology, endoscopy, personal protective equipment, and legal responsibility of the physician. The mucosa of the upper respiratory tract is a potential site of virus replication. The specificity of an ear, nose and throat (ENT) examination and a direct patient-doctor contact favor the transmission of the infection. The authors discussed the elements of self-protection of medical personnel and the legal aspects a risk of the patient contracting the infection in the otolaryngology office. In the case of a direct contact with the patient, the following medical personal protective equipment is required: a cap, a mask with an FFP-2 filter, goggles, an apron and gloves. If, during the visit, exposure to secretions or aerosol from the respiratory tract is expected, the personnel should additionally wear a visor and a waterproof apron. The patient's visit in the clinic should be preceded by telemedicine consultation. Patients should be screened prior to having a direct contact with a physician, using a short patient questionnaire. The questionnaire may consist of simple questions about the characteristic symptoms of the SARS­CoV-2 infection and exposure to a sick person in the past 14 days. The question of staying in the areas of a high infection risk appears of little importance in view of the whole of Poland being perceived as constituting such an area. Due to the spread of the SARS­CoV-2 virus, new procedures for providing medical services have been introduced. In the case of claims on the part of the patient, the only protection the medical personnel or facility can provide is confirmation of scrupulous compliance with medical procedures . Med Pr. 2021;72(3):327-34.


Subject(s)
COVID-19/prevention & control , Infection Control/standards , Otolaryngology/standards , COVID-19/transmission , Health Personnel , Humans , Infection Control/legislation & jurisprudence , Otolaryngology/legislation & jurisprudence , Personal Protective Equipment
10.
JAMA Otolaryngol Head Neck Surg ; 147(6): 575-576, 2021 06 01.
Article in English | MEDLINE | ID: covidwho-1148769
12.
Auris Nasus Larynx ; 48(4): 797-798, 2021 08.
Article in English | MEDLINE | ID: covidwho-1108035
16.
Ear Nose Throat J ; 100(3_suppl): 197S-198S, 2021 06.
Article in English | MEDLINE | ID: covidwho-1067042

ABSTRACT

Tinnitus is a symptom that can significantly affect the quality of life of every patient. In patients with tinnitus, one of the most important diagnostic element is medical history data. Patients classify the pitch and loudness of tinnitus graphically using the visual analog scale (VAS). Visual analog scale and similar questionnaires constitute a valuable addendum of the clinical picture in patients with tinnitus. It seems essential, especially in the light of the information presented in the case report on the probability of correlation between tinnitus and stress and depression associated with social isolation infection avoidance. The knowledge about the patient's hearing condition before contracting COVID-19, the early symptoms of SARS-CoV-2 infection, the method of diagnosis of the infection, the time and method of isolation of the patient, and the time from the diagnosis of COVID-19 to the appearance of otolaryngological symptoms might enable the reader to gain more knowledge on the correlation between COVID-19 and tinnitus. New research reveals that tinnitus is being exacerbated by COVID-19.


Subject(s)
COVID-19 , Tinnitus , Humans , Pandemics , Quality of Life , SARS-CoV-2 , Tinnitus/epidemiology
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