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Sustainability ; 14(6):3643, 2022.
Article in English | ProQuest Central | ID: covidwho-1765915


The COVID-19 pandemic influenced people’s everyday lives because of the health emergency and the resulting socio-economic crisis. People use social media to share experiences and search for information about the disease more than before. This paper aims at analysing the discourse on COVID-19 developed in 2020 by Italian tweeters, creating a digital storytelling of the pandemic. Employing thematic analysis, an approach used in bibliometrics to highlight the conceptual structure of a research domain, different time slices have been described, bringing out the most discussed topics. The graphical mapping of these topics allowed obtaining an easily readable representation of the discourse, paving the way for novel uses of thematic analyses in social sciences.

Clin Chem Lab Med ; 59(12): 2019-2026, 2021 Nov 25.
Article in English | MEDLINE | ID: covidwho-1456116


OBJECTIVES: After exceptional research efforts, several vaccines were developed against SARS-CoV-2 which sustains the pandemic COVID-19. The Comirnaty vaccine showed high efficacy in clinical trials and was the first to be approved for its distribution to the general population. We evaluated the immune response induced by the first vaccine dose in different sex/age groups and subjects with or without naturally present anti-SARS-CoV-2 antibodies. METHODS: As part of an Italian multicenter project (Covidiagnostix), serum samples from 4,290 health-professionals were serologically tested the day of the first vaccination dose, and 21 days later, using two different instrumentations (Siemens-Healthineers and Roche). RESULTS: In total, 97% of samples showed the presence of specific antibodies 21 days after the vaccination dose; the percentage of non-responders increased with age in both genders. Remarkably, naturally seropositive individuals showed antibody persistence up to 11 months and an exceptionally higher vaccination response compared to subjects never infected by SARS-CoV-2. CONCLUSIONS: This study highlighted the importance of the serological test i) to identify naturally SARS-CoV-2 seropositive individuals and ii) to evaluate the antibody level elicited by the first vaccination dose. Both tests, highlighted differences in the immune response, when subjects were stratified by sex and age, and between naturally seropositive and seronegative subjects. The data obtained show how serological tests could play a crucial role in the triage of the population subjected to the vaccination campaign for COVID-19. The definition of suitable instrumentation-specific thresholds is needed to correctly follow eventually acquired post-vaccination immunity in the general population.

Antibodies, Viral/blood , COVID-19 Vaccines/administration & dosage , COVID-19/prevention & control , Immunization Programs , Adult , Aged , Aged, 80 and over , COVID-19/immunology , COVID-19/virology , COVID-19 Vaccines/immunology , Female , Health Personnel , Humans , Immunity, Humoral , Immunoassay , Male , Middle Aged , SARS-CoV-2/isolation & purification , Young Adult
Hum Vaccin Immunother ; 17(10): 3348-3354, 2021 Oct 03.
Article in English | MEDLINE | ID: covidwho-1258722


Vaccination is a key protective factor against COVID-19. Some vaccines have already received emergency authorization from Health Agencies, but growing skepticism and vaccine hesitancy will probably affect COVID-19 vaccination campaigns. In the attempt to shed light on this issue, we conducted an online survey in a population of parents referring to 4 pediatric practices in Naples, Italy in whom we evaluated potential vaccine acceptability in relation to socio-demographic characteristics, perception of personal health and of the impact of COVID-19, and attitudes toward general vaccination practices. Vaccination rates were analyzed also in the corresponding pediatric population.Almost 27% of participants declared they were in favor of vaccinations, and in fact real life vaccination rates in children exceeded the national mean. Only 26.5% of respondents declared they would receive COVID-19 vaccine. Vaccine refusal was attributed to safety concerns in 76% of parents. Specific vaccine attributes further reduced the acceptance rate. Female gender, younger age and lower education level were associated with non-adherence to vaccination. Among extrinsic factors of COVID-19 vaccination, only information from National Health Authorities was significantly associated to vaccine acceptance.The rate of potential COVID-19 vaccine acceptability was very poor in our population of parents. Vaccine hesitancy was mainly due to safety concerns. Demographic and educational factors were correlated to vaccine acceptability. Health education and communication strategies are needed to achieve large-scale vaccine acceptability and finally herd immunity.

COVID-19 , Vaccines , COVID-19 Vaccines , Child , Cross-Sectional Studies , Female , Humans , SARS-CoV-2 , Surveys and Questionnaires , Vaccination