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1.
Pandemic Risk, Response, and Resilience: COVID-19 Responses in Cities around the World ; : 279-292, 2022.
Article in English | Scopus | ID: covidwho-2035615

ABSTRACT

Since January 30, there has been a surge in novel coronavirus (2019-nCoV) outbreak cases in almost all parts of the world except very few countries were able to restraint it with proactive measures. Last year, Uttar Pradesh recorded its first case of COVID-19 on March 4, 2020, in Ghaziabad. Despite having population of over 240 million and high population density as well as the low literacy levels in the state of Uttar Pradesh, the state government was able to deal with the adjoining risk with recovery rate of about 85.34% in the state. The preventive measures against coronavirus outbreak started in the first week of March 2020. There have been reports of total cases of about 384,856 with about 52,160 active cases. While till end of September 2020, 336,981 COVID-19 patients had recovered. Various risk governance strategies and inclusion of modern technologies paved the way for better and efficient public health emergency management of COVID-19 pandemic, effort being made by State government to scale up the team up to 1lakh for effective surveillance on COVID-19. UP Directorate General of Medical and Health services demarcated the health facilities as L1, L1 Covid Care Center, L2, and L3 throughout the state for treatment, depending on their capacity and beds availability. Special training programs designed especially for frontline workers like medical professionals, police personnel, Panchayati Raj, and the rural and urban development departments, together other line department, were carried out at an early stage. There are more than 3962 community kitchens running across the state that are catering to over 3.57lakhs beneficiaries with a total of expenses of around 898,963 USD from Relief Commissioner office. The Labor Department has been tracking the migrated population. State government has launched various schemes, programmes, and food supply to support low-income groups, MGNREGA cards holders, workers, and small wage earners. The four-step action plan that includes Integrated Command and Control Centers (ICCC), door-to-door survey, weekend lockdown for sanitization, and COVID help-desk at all government offices were effective part of risk governance strategies. © 2022 Elsevier Inc. All rights reserved.

2.
Pandemic Risk, Response, and Resilience: COVID-19 Responses in Cities around the World ; : 261-278, 2022.
Article in English | Scopus | ID: covidwho-2035609

ABSTRACT

The COVID-19 pandemic uncovered hidden vulnerabilities of the globalized world that were never witnessed before in modern history. Globalization once seen as the main driver for economic prosperity and poverty reduction became bane and led to the spread of coronavirus in the entire world. While coronavirus broke all the boundaries and spread to each segment of society, the scientific community thrives their best to unleash possible solutions for the effective management of COVID-19. To contain the spread of the virus and effective management of the pandemic, concerted efforts are applied from each section of the society. This chapter presents some of the key strategic approaches through digital means adopted by the Indian state of Bihar in containing the spread of coronavirus. Despite high population density, the mortality rate and rate of infection remained low in Bihar as compared to several Indian states. The concerted efforts to mitigate the impacts of COVID-19 through the use of technology-driven solutions, efficient management of migrant laborer, tracking of patients, and treatment minimized overall patient load and reduced suffering of people of Bihar. The pandemic has also brought a new dimension to the vulnerability and resilience discourse. This chapter also provides insights into the elements of vulnerabilities and resilience related to COVID-19 and how these elements are reshaped from the lens of COVID-19 management. © 2022 Elsevier Inc. All rights reserved.

3.
Recent Advances in Computer Aided Drug Designing ; : 177-205, 2021.
Article in English | Scopus | ID: covidwho-1918953

ABSTRACT

Novel corona virus disease (COVID-19), the causative agent of severe acute respiratory syndrome (SARS-CoV-2) has become a burning issue of 2020. The pandemic has brought the complete world to think about the solutions that can lead us to restart the journey of life in a normal way. Every country is trying all possible steps to combat the disease ranging from shutting the complete economy of the country to the repurposing of drugs and vaccine development. Manual dealing with the virus is a very tedious and highly sensitive issue that requires a high level of safety and every researcher is not sufficient enough to attain it. Regarding this situation, computational approaches have opened a new door for researchers and scientists to think against this deadly issue. The speedy data generation and its analysis through different basic to advance approaches, tools, software, and databases have made bioinformatics capable of giving new insights to the researchers to deal with the current scenario more efficiently. From understanding the underlying mechanism of the virus to the speedy discovery of therapeutic intervention, computational approaches play a significant role. Various Insilco pipelines from genomics and proteomics study, drug discovery, vaccine development, drug repurposing to system biology, network medicine, next-generation sequencing, and machine learning not only help in understanding the disease pathway and mechanism but also speed up the therapeutic process efficiently. The current review deals with the significance and usefulness of computational approaches in combating the corona pandemic. © 2021 by Nova Science Publishers, Inc. All rights reserved.

4.
Indian Journal of Medical Microbiology ; 39:S60-S61, 2021.
Article in English | EMBASE | ID: covidwho-1734474

ABSTRACT

Background:There are more than 350 RT-PCR COVID-19 testing kits commercially available but these kits has not been evaluated for pooled sample testing. Thus, this study was planned to compare and evaluate seven commercially availa- ble kits for pooled samples testing. Methods:Diagnostic accuracy of (1) TRUPCR SARS-CoV-2 Kit (Black Bio, India) (2) TaqPath RT-PCR COVID-19 Kit (Thermo Fisher, USA) (3) Allplex 2019-nCOV Assay (See gene, Korea), (4) Patho detect COVID-19 PCR kit (My Lab, India) (5) LabGun COVID-19 RT-PCR Kit (Lab Genomics, Korea) (6) Fosun COVID-19 RT-PCR detection kit (Fosun Ltd, China) (7) Real time Fluorescent RT PCR kit for SARS CoV – 2 (BGI, china) was evaluated on pre characterised 40 positive and 10 nega- tive COVID-19 sample pools. Results:All seven kits detected all sample pool with low Ct value (<30). While testing weak positive pooled samples with high Ct value (>30);TRUPCR Kit, TaqPath Kit, Allplex Assay and BGI RT PCR kit showed 100% sensitivity, specificity and accuracy. However;Fosun kit, LabGun Kit and Patho detect kit could detect only 90%, 85% and 75% of weak positive samples respectively. [Formula presented] Conclusions:We conclude that all seven commercially available RT-PCR kits included in this study can be used for routine molecular diagnosis of COVID-19. While perform- ing pooled sample testing it might be advisable to use those kits that performed best regarding the positive iden- tification in samples pool i.e. TRUPCR SARS-CoV-2 Kit, TaqPath RT-PCR COVID-19 Kit, Allplex 2019-nCOV Assay and BGI Real time RT PCR kit for detecting SARS CoV – 2.

5.
Brics Law Journal ; 8(2):10-40, 2021.
Article in English | Web of Science | ID: covidwho-1339776

ABSTRACT

The Covid-19 narrative spotlights the necessity to conserve biological diversity (biodiversity) including ecosystems and wildlife. Biodiversity problems are global, and associated governance issues range beyond geographical and spatial boundaries. The globalisation and internationalisation of biodiversity concerns have resulted in the emergence of biodiversity legal frameworks designed to conserve and sustainably use our planet's biological resources. As an "organic and evolving discipline," biodiversity laws are increasingly important and affect the Earth's natural systems that support human life. The article analyses the judicial space that makes, interprets and enforces laws that conserve and support the sustainable use of biodiversity. The proactive, creative judiciary, acting as amicus environment, has produced a major shift in the Indian environmental landscape. The use of public interest litigation (PIL) in both environmental and biodiversity matters is welcomed by the senior judiciary (Supreme Court and High Courts) and also by the specialised environmental tribunal, National Green Tribunal (NGT). The terminological reach of the popular descriptive words, environment, nature and ecology, on occasions including biodiversity, introduced matters litigated in the courts and tribunal. The combination of legal, scientific, and technical expertise in the three judicial fora recognize and consider conservation and protection of biodiversity as an inextricable part of life. The article follows the chronological path of biodiversity litigation, i.e. pre 1992-2002;then 2002-2010 and finally 2010-2020 and examines significant aspects of the three decades of biodiversity litigation.

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