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Archives of Disease in Childhood. Fetal and Neonatal Edition ; 107(4):343, 2022.
Article in English | ProQuest Central | ID: covidwho-1901948


The observation is similar to that of Ju Lee Oei and colleagues, who report an individual patient data meta-analysis of 3 randomised clinical trials comparing the effects on a composite of death or disability of initial resuscitation with 30% or 60% oxygen for preterm infants born <32 weeks gestation. See pages F437 and F386 Surfactant in late preterm and term infants Viraraghavan Vadakkencherry Ramaswamy and colleagues performed a systematic review and meta-analysis of studies of surfactant therapy for term and late preterm infants with respiratory distress syndrome. Most of the information in these more mature infants was derived from observational studies so there were issues with the level of certainty of the evidence showing that surfactant therapy decreased mortality, air leak, persistent pulmonary hypertension of the newborn, duration of ventilation and of hospital stay.

Archives of Disease in Childhood. Fetal and Neonatal Edition ; 105(4):343, 2020.
Article in English | ProQuest Central | ID: covidwho-1255526


With improving outcomes in the infants at highest risk of mortality and morbidity, clinicians are challenged to re-think the norms by which they set their treatment goals and approaches to communication. See page F348 Variations in outcome The Effective Perinatal Intensive Care in Europe (EPICE) collaboration cohort is a geographically defined prospective study of all very preterm (<32 weeks’ gestation) stillbirths and live births in 19 regions of 11 European countries and covers 850 000 births annually. After adjustment for known maternal, pregnancy and infant factors there was wide variation in moderate or severe NDI across countries suggesting that there may be differences in the quality of care provision, treatment and provision of follow-up services for infants across Europe that requires further investigation.