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1.
Geo-Spatial Information Science ; 2023.
Article in English | Scopus | ID: covidwho-2253883

ABSTRACT

The COVID-19 pandemic has completely disrupted and possibly permanently changed the way humans travel. In Puerto Rico, major travel restrictions to the island have persisted at different levels since March 2020, which heavily influenced residents' travel behaviors. However, it remains unclear about how big the impact is and how inequitable it might be. The goal of this study is to evaluate COVID-19's impacts on Puerto Rican's travel behaviors by analyzing travel flows from Puerto Rico to the contiguous US with a modified gravity model. The roles of socioeconomic factors regarding the Puerto Rican travelers and COVID-19 factors regarding the destination US states have been assessed. COVID-19 was a strong deterring factor of travel at the beginning of the pandemic and also in the winter of 2020, but it did not keep Puerto Ricans from traveling during the summer 2020 when most travel restrictions were lifted. We found that the elderly population of Puerto Rico, despite being more vulnerable to COVID-19, were much more likely to travel during the pandemic. We also found that, during the holiday season in 2020, some socioeconomically disadvantaged populations were more likely to be traveling, a direct contradiction to their travel flows the year prior. These findings shed light on about how disproportionately affected populations behavior changed from pre-pandemic to after the pandemic started. With the continuance of the pandemic, this information is extremely valuable for future planning with respect to emergency management, travel regulation, and social benefit. © 2023 Wuhan University. Published by Informa UK Limited, trading as Taylor & Francis Group.

2.
China Oncology ; 32(6):499-511, 2022.
Article in Chinese | EMBASE | ID: covidwho-2263392

ABSTRACT

The corona virus disease 2019 (COVID-19) pandemic continues to severely impact healthcare systems around the world, and patients with cancer are even worse affected owing to compromised immune status and greater exposure risk. In the present review, we retrieved the relevant literature including guidelines and consensuses directly related to the purpose of this study from the PubMed database, and then summarized the research data on cancer and COVID-19, aiming to discuss the personal protection, systemic anti-cancer therapy, outcome of co-infection, and the clinical management strategy in this population. We found that patients with malignant tumors had a higher chance of suffering COVID-19, co-infection of whom had an even worse clinical prognosis, especially for those with lung cancer or hematologic cancers. Systemic chemotherapy may delay the clearance of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) virus of human body, and thus have a negative impact on the clinical outcomes of COVID-19, while certain endocrine therapy and targeted drugs having limited or no impact. There has been no sufficient evidence for the impact of immune checkpoint therapy on the outcomes of COVID-19 till now. It is of great value to strengthen the personal protection of patients, adjust the anti-tumor treatments rationally and optimize the clinical management processes.Copyright © 2022, Editorial Office of China Oncology. All rights reserved.

3.
North American Journal of Economics and Finance ; 63, 2022.
Article in English | Scopus | ID: covidwho-2131936

ABSTRACT

This study seeks to quantify the financial connections between China and Africa. China's increasing investments in Africa have inevitably strengthened the relationship between China and the majority of African countries over the past decade. We find consistent effects of the Shanghai Industrial Index on African stock markets together with some evidence that these relationships strengthened following the onset of the coronavirus pandemic. Markov-Switching analysis affirms these connections while also identifying intensifying effects as we move from periods of low market volatility to periods of high volatility. The African stock markets included in the sample encompass Egypt, Kenya, Morocco, Nigeria, South Africa, Tanzania, Uganda, and Zambia. © 2022 Elsevier Inc.

4.
China Oncology ; 32(6):499-511, 2022.
Article in Chinese | Scopus | ID: covidwho-1964893

ABSTRACT

[] The corona virus disease 2019 (COVID-19) pandemic continues to severely impact healthcare systems around the world, and patients with cancer are even worse affected owing to compromised immune status and greater exposure risk. In the present review, we retrieved the relevant literature including guidelines and consensuses directly related to the purpose of this study from the PubMed database, and then summarized the research data on cancer and COVID-19, aiming to discuss the personal protection, systemic anti-cancer therapy, outcome of co-infection, and the clinical management strategy in this population. We found that patients with malignant tumors had a higher chance of suffering COVID-19, co-infection of whom had an even worse clinical prognosis, especially for those with lung cancer or hematologic cancers. Systemic chemotherapy may delay the clearance of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) virus of human body, and thus have a negative impact on the clinical outcomes of COVID-19, while certain endocrine therapy and targeted drugs having limited or no impact. There has been no sufficient evidence for the impact of immune checkpoint therapy on the outcomes of COVID-19 till now. It is of great value to strengthen the personal protection of patients, adjust the anti-tumor treatments rationally and optimize the clinical management processes. © 2022, Editorial Office of China Oncology. All rights reserved.

5.
Research of Environmental Sciences ; 34(10):2509-2516, 2021.
Article in Chinese | Scopus | ID: covidwho-1497975

ABSTRACT

In order to investigate the distribution and risk of microbial aerosols in residential areas after the COVID-19 in Wuhan Ctiy, Changqing Garden residential area, a mature community was selected as a case in this study. From October to December 2020, the Andersen-sixstage microbial air sampler was used to collect samples in six typical places in this residential area, and the microbial aerosol concentration was determined by the plate count method. In addition, the health risk assessment was evaluated according to the Chinese Population Exposure Parameters Manual (Adult Volume). The results showed that: (1) The concentration of microbial aerosol can be ranked in this order: fresh food market >underground parking lot >food street >central basketball court >central square >green pavilion. (2) The concentration of bacteria and fungus aerosol was different in different places, and the maximum aerosol concentration occurred in the fresh food market ((1525.32±1311.31) CFU/m3) and the food street ((1296.82±113.84) CFU/m3), respectively. (3) Take the air microbial concentration in typical places as the evaluation standard: the central basketball court, green pavilion and central square were clean, the fresh food market and underground parking lot were slightly polluted, and the food court was lightly pollution. (4) The median diameter of microbial aerosols was less than 4.7 μm, which can easily cause lower respiratory tract infections in residents. (5) The Hazard Quotient (HQ) of the typical places from October to December 2020 was less than 1, indicating that the health risk of microbial aerosol exposure in Changqing Garden residential area was relatively small. This research shows that the air quality of the Changqing Garden residential area is good under the epidemic prevention and control normalized measures, which meets the requirements for sanitary conditions in the post-COVID-19 era. © 2021, Editorial Board, Research of Environmental Sciences. All right reserved.

6.
Journal of Clinical Oncology ; 39(3 SUPPL), 2021.
Article in English | EMBASE | ID: covidwho-1146704

ABSTRACT

Background: To understand the factors associated with timing of adjuvant therapy in the management of intrahepatic and extrahepatic cholangiocarcinoma and the impact of delays on overall survival (OS). Methods: Data from the NCDB for patients with pathologically proven non-metastatic adenocarcinoma of the bile ducts from 2004 to 2014 were pooled and screened. Patients were included only if they underwent surgery and adjuvant chemotherapy (CMT) and/or radiotherapy (RT). Patients who underwent neoadjuvant therapy or received CMT or RT with palliative intent were excluded. Pearson's chisquared test and multivariate logistic regression analyses were used to assess the distribution of demographic, clinical, and treatment factors. After propensity-score matching with inverse probability of treatment weighting, OS was compared between patients who had initiation of adjuvant therapy past various time points using Kaplan Meier analyses and doubly-robust estimation with multivariate Cox proportional hazards modeling. Results: In total, 7,422 patients in our analysis underwent adjuvant treatment. This represented 43% of the study cohort of 17,123 patients. Of the patients who underwent adjuvant treatment, 3,956 (53%) initiated adjuvant therapy by two months, 6,234 (84%) by 3 months and 6,987 (94%) by four months. High-grade disease, macroscopically positive margins, tumors larger than five centimeters, and unknown LVSI status, were associated with earlier initiation of adjuvant treatment at two months or earlier. Patients who received early adjuvant therapy were also more likely to be treated with a combination of CMT and RT. Factors associated with delay of adjuvant therapy beyond three months postsurgery included Charlson scores of one or greater and Hispanic race. After propensity score weighting, there was no survival difference between groups when comparing initiation of adjuvant therapy before or after two, three or four month time pointsConclusions: We identified a number of patient characteristics related to the timing of initiating adjuvant therapy in patients with biliary cancers. There were no significant difference in OS associated with delaying adjuvant therapy beyond two, three or four month time-points. Our findings are relevant in the era of COVID-19 when minimizing patient exposure to healthcare settings during a pandemic may need to be considered when deciding on the timing of adjuvant therapy. If a delay is necessary, our results suggest that there is no survival detriment to initiating adjuvant therapy beyond three or four months after surgery for biliary cancers.

7.
Annals of Gis ; 26(4):319-327, 2020.
Article in English | Web of Science | ID: covidwho-1030995

ABSTRACT

Massive and rapid testing is crucial for containing the spread of COVID-19. Health and policy planners must ensure that access to and uptake of SARS-CoV-2 testing is adequate and equitable. This study measures the spatial accessibility to testing sites in Florida at the census tract level at the end of May 2020, using the 2-step floating catchment area method that integrates both driving and walking modes. Accessibility scores were found to be heterogeneous across geographic regions and among different groups of people. In particular, many rural areas were in a testing desert. While people in larger cities tended to have better accessibility to testing, many did not have adequate accessibility at that time due to both capacity limitations and spatial factors. In particular, people without access to private vehicles and the elderly faced disadvantages in accessibility to testing sites even in urban areas. However, Black and low-income groups were disproportionally concentrated in neighbourhoods with above-average accessibility due to their closer proximity to testing sites. These results suggest that increased efforts are needed to reach vulnerable populations, including the elderly and those without private vehicles.

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