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LANCET NEUROLOGY ; 21(4):308-310, 2022.
Article in English | Web of Science | ID: covidwho-1905073

ABSTRACT

The past two decades have seen an increasing number of outbreaks of public health importance, of which the most recent and devastating is COVID-19, with a death toll of more than 5 million people and around 30% of survivors reporting long-term neurological symptoms. Other recent outbreaks include Zika virus infection, mainly affecting populations in South America and in Asia, West Nile virus in the Americas, and enterovirus associated acute flaccid paralysis in North America. Hundreds of other endemic pathogens can also affect the nervous system. Conditions such as communityacquired bacterial meningitis and tropical neurological infections remain major drivers of death and disabilitylike neurocysticercosis, HIV, and Zika virus not only cause neurological injury in the acute setting, but also contribute substantially to long-term sequelae, such as epilepsy, or cognitive impairment. can damage the nervous system directly and those that have indirect effects on the nervous system. Emerging and re-emerging neuroinfectious diseases, including arthropod-borne infections, are of growing concern to the global-health community, given the multiple drivers for disease propagation that include climate change,2 expanding host susceptibility, and pathogen-related

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