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researchsquare; 2021.


Background: Coronavirus disease (COVID-19) caused by a highly contagious virus called severe acute respiratory syndrome coronavirus 2 emerged in China at the end of 2019 and became a major threat to health around the world. The health experts are still learning more about the detailed knowledge of the natural course and the severity of COVID-19. The study aimed to assess the prevalence and association of severity with demographic characteristics, initial presenting symptoms, and comorbidities among COVID-19 patients in Treatment Centers, Myanmar. Methods: : A cross-sectional study was conducted at Hmawbi and Indine Treatment Centers from November to December 2020 and a total of 176 adult COVID-19 patients participated in this study. Data were collected by telephone surveys using structured questionnaires. The odds ratio with a 95% confidence interval was used as a measure of association and the independent associated factors for severity (pneumonia) were investigated using logistic regression analysis. Results: : In total, 76.7% were symptomatic patients and the most common presenting symptoms were fever 43.2%, loss of smell 42.0%, and cough 25.6%. The prevalence of comorbidity in COVID-19 patients was 35.8% and the most common comorbidities were hypertension 19.9%, heart diseases 9.7%, and diabetes mellitus 9.1%, respectively. As a severity, 23.3% of patients had signs of pneumonia. The associated factors of pneumonia were aged 60 years and older [Adjusted Odds Ratio (AOR) = 8.82, 95 % CI: 2.68-29.08] , overweight or obese (AOR: 3.33, 95% CI: 1.30-8.54), current smoking (AOR: 15.29, 95% CI: 2.91-80.37), and alcohol drinking (AOR: 7.04, 95% CI: 1.40-35.31). Thirty percent of symptomatic patients present with pneumonia. Conclusions: : Nearly one-fourth of the patients developed pneumonia. The COVID-19 patients who are aged 60 years and older, overweight or obese, current smokers, and alcohol drinkers should be monitored carefully during the course of treatment to reduce the disease severity.

Coronavirus Infections , Diabetes Mellitus , Heart Diseases , Obesity , Pneumonia , COVID-19