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1.
Chest ; 162(4):A1029, 2022.
Article in English | EMBASE | ID: covidwho-2060756

ABSTRACT

SESSION TITLE: Drug-Induced Critical Care SESSION TYPE: Rapid Fire Case Reports PRESENTED ON: 10/19/2022 12:45 pm - 1:45 pm INTRODUCTION: Intravenous magnesium sulfate (MgSo4) is commonly used for inpatient magnesium repletion. However, it is infrequently shown to be associated with the development of pulmonary edema. We present a case of acute hypoxic respiratory failure due to pulmonary edema after starting magnesium infusion in a patient recovering from COVID-19. CASE PRESENTATION: 60 year old female with a history of metastatic breast cancer presented with hypoxic respiratory failure due to COVID-19. CT angiogram of her chest showed diffuse bilateral ground-glass opacities with no evidence of pulmonary embolism. She had prolonged weaning from high flow nasal cannula and was treated with antibiotics, remedesivir, and dexamethasone. Following treatment, her inflammatory markers significantly improved. On day thirty, she was on 25 L at 45% FiO2 on high flow nasal cannula. Her magnesium level was low at 1.5 mg/dl, and 2 grams of intravenous MgSo4 was given for replacement. A few minutes after starting the infusion, the patient complained of metallic taste, severe shortness of breath, and tachypnea with a drop in oxygen saturation to 67%, which improved with increasing oxygen. CXR showed worsening perihilar infiltrates compared to prior, suggesting acute pulmonary edema. An echocardiogram showed normal function without evidence of structural abnormalities. Thyroid function was normal. She did not receive any blood products or opioids prior to this event. She responded very well to diuresis, was weaned to 5L nasal cannula in three days, and was eventually discharged on 2L supplemental oxygen. DISCUSSION: Pulmonary edema is due to the movement of excess fluid into the alveoli. It can be due to cardiogenic and noncardiogenic causes. Noncardiogenic pulmonary edema is due to a rise in transcapillary filtration, causing an increase in capillary permeability due to several factors, most importantly direct endothelial damage due to inflammation. Mechanisms for MgSo4 induced pulmonary edema are unknown, but theories include direct capillary damage or transient cardiac depression. It is seen in studies to be an independent risk factor for the development of pulmonary edema in pregnancy. Higher risk is associated with faster MgSo4 infusion, less concentrated MgSo4, and infection[1]. She was on abemaciclib for breast cancer before her admission, known to cause pneumonitis but was thought unlikely to cause her acute decompensation. The lack of other etiologies explaining sudden respiratory failure, her rapid improvement on stopping magnesium, and her response to diuretics supported our diagnosis. CONCLUSIONS: Treatment of noncardiogenic pulmonary edema involves addressing the underlying cause of the event and is mainly supportive. Given how commonly Mgso4 is used for repletion in the inpatient setting, MgSo4 induced pulmonary edema should be in the differential for acute hypoxic respiratory failure and promptly addressed. Reference #1: Samol JM, Lambers DS. Magnesium sulfate tocolysis and pulmonary edema: the drug or the vehicle? Am J Obstet Gynecol. 2005 May;192(5):1430-2. doi: 10.1016/j.ajog.2005.02.093. PMID: 15902128. DISCLOSURES: No relevant relationships by Nasir Alhamdan No relevant relationships by Harshitha Mergey Devender No relevant relationships by Abira Usman No relevant relationships by Vishruth Vyata No relevant relationships by Harika Yadav

2.
Chest ; 162(4):A623-A624, 2022.
Article in English | EMBASE | ID: covidwho-2060649

ABSTRACT

SESSION TITLE: Unusual Pneumonias SESSION TYPE: Rapid Fire Case Reports PRESENTED ON: 10/19/2022 12:45 pm - 1:45 pm INTRODUCTION: Invasive pulmonary aspergillosis (IPA) commonly occurs in the setting of immunosuppression. Underlying lung disease is a well-known risk factor for IPA;however, interstitial lung disease (ILD) has not been recognized as a risk factor for IPA[1]. CASE PRESENTATION: A 40-year-old male with a history of a failed kidney transplant now on hemodialysis (HD), Juvenile Rheumatoid Arthritis, Mixed Connective Tissue Disease, Aspergilloma led to right lower lobectomy a year ago, COVID-19 infection three months ago, chronic lung disease (CLD) thought to be due to Nonspecific interstitial pneumonia (NSIP) presented with dyspnea. He had several hospitalizations for respiratory failure needing intubation or NIPPV, broad-spectrum antibiotics, steroids, and HD with improved respiratory status, eventually discharged. Bronchoalveolar lavage fluid culture grew aspergillus terreus but was negative for Pneumocystis (PCP), bacteria, acid-fast bacilli, and Nocardia. The transbronchial biopsies showed mixed inflammatory type and fungal forms in one specimen. Additionally, the initially negative galactomannan converted into a serial rise in galactomannan (>3.75 Index) along with a rise in beta d-glucan (>500 pg/ml). Unfortunately, he had gaps in antifungals and was readmitted similarly. Micafungin was added for dual fungal coverage and was planned for surgical lung biopsy to characterize ILD further once his respiratory status allows. DISCUSSION: He has multiple risk factors for developing IPA, such as high-dose steroids for ILD and recent COVID infection. Initially, respiratory failure was thought to be due to exacerbation of ILD, and suspicion for IPA was low because of lack of neutropenia, negative fungal biomarkers, lack of classic findings on lung imaging, and in-hospital clinical improvement with steroids. However, the eventual course of recurrent respiratory failure while on high-dose steroids, along with gaps in antifungal therapy and continued growth of Aspergillus, made IPA the most likely diagnosis. For IPA, the mainstay of treatment is both adequate antifungal therapy and reduction in immunosuppression to the extent possible[2];however, it is unclear if his underlying ILD can tolerate steroid taper. He will need a lung transplant after adequately treating IPA. CONCLUSIONS: There are no current guidelines on simultaneously treating IPA and NSIP. It is challenging to balance reduction in immunosuppression as tolerated for ILD and concurrently maintain antifungal therapy. During this patient's hospitalization, there have been considerations of using a steroid-sparing agent for his suspected NSIP, however, in the setting of active infection, its benefit is debatable.[3] Reference #1: Matsuyama H, Miyoshi S, Sugino K, et al. Fatal Invasive Pulmonary Aspergillosis Associated with Nonspecific Interstitial Pneumonia: An Autopsy Case Report. Intern Med. 2018;57(24):3619-3624. doi:10.2169/internalmedicine.1144-18 Reference #2: Thomas F. Patterson, George R. Thompson, III, David W. Denning, Jay A. Fishman, Susan Hadley, Raoul Herbrecht, Dimitrios P. Kontoyiannis, Kieren A. Marr, Vicki A. Morrison, M. Hong Nguyen, Brahm H. Segal, William J. Steinbach, David A. Stevens, Thomas J. Walsh, John R. Wingard, Jo-Anne H. Young, John E. Bennett, Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America, Clinical Infectious Diseases, Volume 63, Issue 4, 15 August 2016, Pages e1–e60, https://doi.org/10.1093/cid/ciw326 Reference #3: Mezger, M., Wozniok, I., Blockhaus, C., Kurzai, O., Hebart, H., Einsele, H., & Loeffler, J. (2008). Impact of mycophenolic acid on the functionality of human polymorphonuclear neutrophils and dendritic cells during interaction with Aspergillus fumigatus. Antimicrobial agents and chemotherapy, 52(7), 2644–2646. https://doi.org/10.1128/AAC.01618-07 DISCLOSURES: No relevant relationships by Nasir Alhamdan No relevant relati nships by Parth Jamindar No relevant relationships by Harshitha Mergey Devender No relevant relationships by Abira Usman No relevant relationships by Vishruth Vyata

4.
ASAIO Journal ; 68:65, 2022.
Article in English | EMBASE | ID: covidwho-2032184

ABSTRACT

Objectives: The purpose of this study was to compare the outcomes of chest tubes (CT) inserted via three approaches in COVID-19 patients undergoing extracorporeal membrane oxygenation (ECMO): open thoracostomies (OT), percutaneously at bedside (PERC), and percutaneously by interventional radiology (PERC IR). Methods: We conducted an institutional review board - approved retrospective study of all COVID-19 patients who required CT placement while undergoing ECMO in our institution from February 2020 till February 2022. Insertions prior to ECMO cannulation or after decannulation, and those related to post-operative lung transplantation during ECMO were excluded from our analysis. Depending on the insertion approach, eligible CT insertion events were divided in three groups: OT, PERC and PERC IR. Data regarding patients' demographics and CT characteristics, clinical indications and associated complications for each group were collected and analyzed. Bleeding related to CT insertion was diagnosed based on requirement of blood transfusion, cessation of anticoagulation and/or ongoing bloody CT output. Results: Study criteria were met by 43 patients, with 35 (83.7%) of male sex. Mean age was 45 years. Mean BMI was 31.6 kg/m2. Forty patients (93.0%) had COVID-related acute respiratory distress syndrome as primary diagnosis. All patients but one had been receiving therapeutic anticoagulation which was held prior to CT insertion. Eighty-seven CT insertion events were recorded, of which 34 (39.1%) comprised the OT group, 20 (23.0%) the PERC group, and 33 (37.9%) the PERC IR group. Table 1 demonstrates a descriptive comparison of CT and insertion data among the three groups. Table 2 depicts the major outcomes among the three groups. Conclusions: For COVID-19 patients on ECMO, insertion of CTs percutaneously by IR is associated with significantly fewer bleeding episodes, transfusions, thoracic consults and explorations in the operating room compared to bedside OT or percutaneous CTs. One third of the percutaneously placed CTs by IR required tube upsizing in the IR suite, a rate still lower compared to the overall CT manipulations or repeat interventions required for CTs inserted via OT or percutaneously at bedside. (Table Presented).

5.
Karbala International Journal of Modern Science ; 8(3):446-454, 2022.
Article in English | Scopus | ID: covidwho-2026614

ABSTRACT

Global infection and mortality rates have soared to millions due to SARS-CoV-2 human-to-human transmission via droplets which then declared as pandemic. This study examined the created cold plasma equipment (CPE) effectiveness in reducing COVID-19 transmission in a confined space. CPE sucked air using a fan in a test chamber then pushed it into a cold plasma reactor. The results indicated that it was able to terminate all SARS-CoV-2 variants along with bacteria and fungi indoors by keeping it turned on for 30 min' minimum. CPE was proven as safe and effective to hinder virus transmission with the acceptable ozone emission as the side effect. © 2022 University of Kerbala.

6.
Intellectual Discourse ; 30(1):213-236, 2022.
Article in English | Scopus | ID: covidwho-1940299

ABSTRACT

This article analytically discusses how the Quran commands Muslims to be prudent in the face of a pandemic crisis. The Quran is the holy book of Islam and is considered by Muslims to be the word of God and is a valid source of guidance alongside science advisories from government authorities. Using a qualitative method, this study investigates the Quranic assertion that in the face of a pandemic crisis, Muslims are required to do charitable deeds and keep striving with the hope that the solution to problems people face can be actively found, rather than just fatalistically surrendering to fate and Allah's power alone. In this regard, the Quran commands Muslims to be prudent and to take precautions against the spread of disease, practice charity, endure, not be fooled by false gossip and to place trust in the religious and health authorities during times of crisis. © 2022 International Islamic University Malaysia. All rights reserved.

7.
European Stroke Journal ; 7(1 SUPPL):132, 2022.
Article in English | EMBASE | ID: covidwho-1928105

ABSTRACT

Background: Stroke is a leading cause of disability in adults, requiring regular patient-therapist contacts to achieve greater functional regain of the affected extremities. Factors such as the recent Covid-19 pandemic have limited access to Rehabilitation services across several communities globally. A proliferation of telerehabilitation to ameliorate these healthcare challenges has been palpable in the recent years across the globe. Purpose: To assess the effect of telerehabilitation in facilitating upper extremity home program and associated functional regain among chronic stroke survivors. Methods: Two groups pretest-posttest study design was employed. Participants were instructed to perform upper extremity home programs three times a week for four weeks. A task-oriented, individually tailored, and intensive home-based telerehabilitation program was administered to the participants using audio calls. Upper extremity functional status was assessed using Fugl-Meyer Motor Assessment, and Wolf Motor Function Test. The Barthel Index was used to assess the extent of activities of daily living. Results: A total number of 14 people were recruited (experimental n=7 age, 58 ± 5.83;control n=7, age 50.71 ± 8.62). Participants showed significant improvement for Fugl-Meyer Motor Assessment changed from 17.57 to 25.86 (p=0.02), whereas Wolf Motor Function Test changed from 28.14 to 43.71 (p=0.03). Conclusions: Amidst situations restricting regular hospital visit among stroke survivors;telerehabilitation could serve as an adjunct therapeutic option for upper extremity rehabilitation. Future studies should employ a randomized controlled trial design with a larger sample size to confirm the utility of telerehabilitation.

8.
Pakistan Journal of Medical and Health Sciences ; 16(5):718-720, 2022.
Article in English | EMBASE | ID: covidwho-1918403

ABSTRACT

Background: Health care burden has increased since the pandemic of Covid-19 has emerged. The healthcare resources are limited currently and majority surgeries have been postponed because of the current pandemic. Therefore, the main concern of carrying out any surgery at current point is mainly in those patients that are landing in emergency. Symptomatic inguinal hernia being a common presentation in emergency can be dealt by applying local anesthesia. Objective: To evaluate the outcome (in terms of efficacy and safety) of local anesthesia for managing symptomatic inguinal hernia in a tertiary care hospital during current Covid-19 pandemic. Methodology: It was a descriptive study.60 males were enrolled with inguinal hernia of age 30-60 years. IV line was secured and local anesthesia was administered under aseptic measures. Lichtenstein repair, a mesh technique was applied in all patients for treating the inguinal hernia. Patients were evaluated postoperatively after 2 hours and 6 hours for any complications. Results: Mean age of the patients was 38.2±10.542, Mean time to eat was 3.85 ±3.138. Mean time to ambulate was 4.37 ±2.51. Mean pain score was 5.78± 2.131 postoperatively and after 6 hours it was 2.24 ±0.84. Indirect hernia was present in 74% patients whereas direct hernia was present in 26%. 6.67% patients had nausea/vomiting, 3.3% developed hematoma and 1.67% had wound infection. Conclusion: Local anesthesia is effective in all patients who have to undergo inguinal hernia surgery, in terms of efficacy and safety.

11.
Anesthesia and Analgesia ; 132(5S_SUPPL):235-237, 2021.
Article in English | Web of Science | ID: covidwho-1695454
13.
Ann Ib Postgrad Med ; 19(Suppl 1):90-99, 2021.
Article in English | PubMed | ID: covidwho-1661033

ABSTRACT

INTRODUCTION: Kaduna State is among the three States with the highest number of confirmed COVID-19 cases. The objective of this study was to assess the knowledge, risk perception and practices of staff towards prevention and control of COVID-19 infection in schools to provide policy makers, education and health managers required information to manage the epidemic as the schools prepare to re-open. METHODS: This was a school-based survey conducted using purposive sampling of 55 schools located in nine LGAs with the highest number of reported COVID-19 cases as at October 2020. Five schools with the highest students'/pupils' enrollment in each of the LGA were selected and all staff were interviewed. Information on knowledge, risk perception and practices of prevention was collected. Descriptive statistics were generated using Stata v14 software. RESULTS: A total of 1065 staff in 55 schools completed the interview. Major sources of information are television (73%), radio (61%), and social media (57%);and 76% indicated that a virus is the causative agent of COVID-19. Overall, 70%, 19%, 7%, 9.3% and 0% respectively had adequate knowledge of cause, preventive measures, respiratory hygiene, modes of transmission and symptoms of COVID-19;however only 14% ever attended a workshop on COVID-19. Eighty-two percent and 89% respectively believed in the efficacy of face masks and handwashing as means of prevention;39% thought that they are likely to contract COVID-19. Ninety-nine percent and 90% have ever used face mask and hand sanitizer to prevent COVID-19;96% and 85% respectively have use these methods in previous 24hours. Between 42% and 73% of schools needed additional commodities/requirements/supplies to comply fully with COVID-19 prevention protocols. CONCLUSION: While knowledge of COVID-19 is suboptimal, perception is positive and practice is high. Thus, teachers need to be well informed and encouraged to sustain current levels of preventive measures. Government needs to provide schools with adequate preventive commodities to ensure compliance.

14.
Circulation ; 144(SUPPL 1), 2021.
Article in English | EMBASE | ID: covidwho-1630502

ABSTRACT

Introduction: Messenger RNA (mRNA) based vaccines (Pfizer/BioNTech and Moderna) have shown to be highly effective at providing immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Aims: To study the duration of immunity, evolution of IgG antibody levels and IgG avidity (an index of antibody-antigen binding strength), and differences in immune responses between (mRNA) based vaccines. Methods: We performed a prospective study of 72 subjects without a history of SARS-CoV-2 who received both doses of either the Pfizer (n=55) or Moderna (n=17) mRNA vaccine. Anti-spike protein receptor binding domain (RBD) IgG antibody levels and IgG avidity indices were measured longitudinally using a qualitative finger stick MidaSpot™ rapid test at the point-of-care and a quantitative dry blood spot-based pGOLD™ laboratory test over ∼ 4 months post-vaccination. Results: On average, anti-RBD IgG antibody levels peaked at ∼2 weeks after second vaccination dose and declined thereafter, while antibody avidity increased suggesting antibody maturation (Figure). Moderna vaccine recipients exhibited higher side effect severity, higher peak anti-RBD IgG antibody levels and higher avidity up to the 90 days point, when compared to Pfizer vaccine recipients. Nevertheless, the differences in antibody and avidity levels diminished at ∼ 120 days post-vaccination, in line with the similar efficacy of the two vaccines. A qualitative MidaSpot finger stick rapid test detected 100% anti-SARS-CoV-2 RBD positivity for fully vaccinated subjects in both Pfizer and Moderna cohorts and turning negative greater than 90 days post-vaccination for 9% of subjects in the Pfizer cohort whose quantitative anti-IgG fell below the 25-percentile levels. Conclusions: Longitudinal quantitative measurements of anti-RBD antibody and avidity levels provide insight to immune responses and could aid the assessment of immunity and vaccine effectiveness.

15.
BMC Cardiovasc Disord ; 21(1): 375, 2021 08 04.
Article in English | MEDLINE | ID: covidwho-1339117

ABSTRACT

BACKGROUND: Half of U.S. adults have received at least one dose of the COVID-19 vaccines produced by either Pfizer, Moderna, or Johnson and Johnson, which represents a major milestone in the ongoing pandemic. Given the emergency use authorizations for these vaccines, their side effects and safety were assessed over a compressed time period. Hence, ongoing monitoring for vaccine-related adverse events is imperative for a full understanding and delineation of their safety profile. CASE PRESENTATION: An 22-year-old Caucasian male presented to our hospital center complaining of pleuritic chest pain. Six months prior he had a mild case of COVID-19, but was otherwise healthy. He had received his first dose of the Moderna vaccine three days prior to developing symptoms. Laboratory analysis revealed a markedly elevated troponin and multiple imaging modalities during his hospitalization found evidence of wall motion abnormalities consistent with a diagnosis of perimyocarditis. He was started on aspirin and colchicine with marked improvement of his symptoms prior to discharge. CONCLUSIONS: We present a case of perimyocarditis that was temporally related to COVID-19 mRNA vaccination in an young male with prior COVID-19 infection but otherwise healthy. Our case report highlights an albeit rare but important adverse event for clinicians to be aware of. It also suggests a possible mechanism for the development of myocardial injury in our patient.


Subject(s)
COVID-19 Vaccines/adverse effects , Myocarditis/chemically induced , Anti-Inflammatory Agents/therapeutic use , Aspirin/therapeutic use , COVID-19 Vaccines/administration & dosage , Colchicine/therapeutic use , Humans , Immunization Schedule , Male , Myocarditis/diagnostic imaging , Myocarditis/drug therapy , Myocarditis/physiopathology , Recovery of Function , Treatment Outcome , Young Adult
16.
International Journal of Research in Pharmaceutical Sciences ; 12(3):2014-2019, 2021.
Article in English | EMBASE | ID: covidwho-1326130

ABSTRACT

COVID-19 impacted many lives around the globe, leading to a nationwide lockdown in India from the 25th of March 2020. Home confinement, physical and social isolation, the spread of false news through social media, fear of contracting the disease, lack of physical activity, and work-from-home situations have affected the mental status and sleep quality of individuals during the lockdown. We intended to identify the effect of belly breathing exercise in reducing the depression, anxiety and stress levels in individuals who work-from-home during the lockdown. A hundred participants were identified through snowball sampling and were divided into two equal groups. Group A received a health education program and belly breathing techniques, whereas group B was provided with a health education program alone. DASS 21 and single item Sleep Quality Scale was assessed before recruitment and after three weeks of intervention in both groups. Signiicant reduction in depression, anxiety, and stress levels were observed in group A (p<0.001) than that of group B. Participants who underwent belly breathing also reported signiicant improvement in sleep quality after three weeks of intervention. Belly breathing has found to be an effective and simple technique to instruct and perform, which significantly reduces depression, anxiety and stress levels in individuals who work from home and are in need of medical advice for their mental health status. We suggest the use of belly breathing in improving the mental status in any black swan events such as home quarantine or strict physical isolation measures, and even during any stressful situations.

17.
BMC Public Health ; 21(1): 1214, 2021 06 24.
Article in English | MEDLINE | ID: covidwho-1282250

ABSTRACT

BACKGROUND: Following the COVID-19 pandemic, school closures were part of the global public health response to limit community spread of the virus. In recent times, there has been an emphasis on safe school re-opening. This concept is likely to differ between developed and developing country settings. There are however no published studies on barriers hindering safe school re-opening within developing country contexts. This study evaluates aspects of the school health program (SHP) in some selected Nigerian schools that might relate to the pandemic control during school re-opening. METHODS: In 2017, we conducted a cross-sectional survey of the SHP of 146 registered primary schools in Gwagwalada Area Council in Abuja, Nigeria. These schools provided services to about 54,562 students. We used direct observational methods and interviewer-administered questionnaires to assess the SHP of each school. We compare SHP characteristics that might relate to COVID-19 control in schools across government-owned (public) and privately-owned (private) schools using a pre-defined framework. RESULTS: Public school to pupil ratios was more than six times that of private schools. Only 6.9% of all surveyed schools employed qualified health personnel. Although 8 in every 10 schools conducted health talks for communicable disease control, the use of temporary isolation and school-based immunization were low at 1.4 and 2.7% respectively. Pipe-borne water access was present in 4 of 10 schools, with public schools having more limited access than private schools (p = 0.009). Similarly, less proportion of public schools had access to soap for handwashing (p < 0.001). Adequate classroom ventilation was present in 63% of surveyed schools, with private schools having more limited ventilation (p < 0.001). CONCLUSIONS: Overcrowding and infrastructural deficits within developing country contexts represent barriers to safe school re-opening during the COVID-19 pandemic. In these settings, there needs to be tailored and innovative strategies which consider local practical realities when designing the COVID-19 control programs during school re-opening.


Subject(s)
COVID-19 , Pandemics , Cross-Sectional Studies , Developing Countries , Humans , Nigeria , Pandemics/prevention & control , SARS-CoV-2 , Schools
18.
Turkish Journal of Physiotherapy and Rehabilitation ; 32(2):1668-1672, 2021.
Article in English | Scopus | ID: covidwho-1218830

ABSTRACT

As a midwife, it is essential to provide information on pregnant women's health problems, including exercise for pregnant women. Providing the information aims that pregnant women will continue to do light movements at home (sports) and the COVID-19 pandemic.This pandemic problem currently happening around the world results in limited outdoor activities for pregnant women. Therefore, we created an application,"Tanya Bidan," addressed to pregnant women. By downloading this Android application, they can see material or videos such as balanced nutrition material for pregnant women, exercise material for pregnant women, the material on breastfeeding techniques for postpartum mothers, and material on implant contraceptive methods on couples of childbearing age. Methods: This type of research was quasi-experimental (one group pre-test and post-test design). This study's sample was 72 pregnant women whose gestation age was 24-42 weeks in the Padongko Community Health Center's work area, conducted from June-February 2021. Pre-test and post-test using a questionnaire on pregnant women's exercise knowledge were used to collect the data. The Wilcoxon test was applied for data analyses.Result: Statistically, the pretest data gained a mean value of 1.01, with a minimum value of 1 and a maximum of 2. At the post-test, the mean value was 2.46, with a minimum of 2 and a maximum of 3. Based on the Wilcoxon test, the a-symp sigh (2 tailed) had a value of 0.000 <0.05.It showsan increase in exercise knowledge during the pre-test and post-test with the "Tanya Bidan" application.Conclusion:The usage of "Tanya Bidan" can effectively increase the knowledge of pregnant women's exercise in the COVID-19 era. © 2021 Turkish Physiotherapy Association. All rights reserved.

19.
J Nucl Cardiol ; 28(5): 2167-2173, 2021 10.
Article in English | MEDLINE | ID: covidwho-1202853

ABSTRACT

BACKGROUND: As the coronavirus pandemic progresses, patients that have recovered from COVID-19-related hospitalization require resumption of care for other medical issues. Thus far, the literature has not detailed the experience of stress testing in this patient population. METHODS: We retrospectively reviewed patients that recovered from COVID-19-related hospitalizations and underwent SPECT MPI studies at the University of Alabama at Birmingham Medical Center. RESULTS: 15 patients (median age 60 years, 67% male) were identified with COVID-19-related hospitalization and then underwent SPECT MPI imaging after recovery. During COVID-19-related hospitalization (median length of stay 8 days), patients received various COVID-19 therapies; 3 required mechanical ventilation. Stress tests (4 Exercise, 11 Pharmacologic) were performed 65 days (interquartile range 31-94 days) after the diagnosis of COVID-19. None of the patients experienced serious adverse events during or after stress testing. One patient required regadenoson reversal using aminophylline due to chest pain. CONCLUSION: Over time, more patients that recover from COVID-19 infection will require MPI testing for myocardial ischemia evaluation. Our study provides some information regarding performing stress testing in patients who have recently recovered from COVID-19 infections requiring hospitalization. Further studies are recommended to establish formal protocols for testing in this cohort.


Subject(s)
COVID-19/diagnostic imaging , COVID-19/physiopathology , Exercise Test , Myocardial Perfusion Imaging , Tomography, Emission-Computed, Single-Photon , COVID-19/therapy , Female , Hospitalization , Humans , Male , Middle Aged , Respiration, Artificial , Retrospective Studies , Time Factors
20.
IAES International Journal of Artificial Intelligence ; 10(1):35-42, 2021.
Article in English | ProQuest Central | ID: covidwho-1168156

ABSTRACT

The need for elucidating the effects of environmental factors in the determination of the novel corona virus (COVID-19) is very vital. This study is a methodological study to compare three different test models (1. Artificial neural networks (ANN), 2. Adaptive neuro fuzzy inference system (ANFIS), 3. A linear classical model (MLR)) used to determine the relationship between COVID-19 spread and environmental factors (temperature, humidity and wind). These data were obtained from the studies (Pirouz, Haghshenas, Haghshenas, & Piro, 2020) with confirmed COVID-19 patients in Wuhan, China, using temperature, humidity and wind as the independent variables. The measured and the predicted results were checked based on three different performance indices;Root mean square error (RMSE), determination coefficient (R2) and correlation coefficient (R). The results showed that ANFIS and ANN are more promising over the classical MLR models having an average R-values of 0.90 in both calibration and verification stages. The findings indicated that ANFIS outperformed MLR and ANN. In addition, their performance skills boosted up to 25% and 9% respectively based on the determination coefficient for the prediction of confirmed COVID-19 cases in Wuhan city of China. Overall, the results depict the reliability and ability of AI-based models (ANFIS and ANN) for the simulation of COVID-19 using the effects of various environmental variables.

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