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Frontiers in Environmental Science ; 2023.
Article in English | ProQuest Central | ID: covidwho-2235977


Purpose: Scholars have concentrated their efforts on COVID-19's impact on industries worldwide in order to manage timely supply chain disruptions. Epidemic outbursts are a unique supply chain risk that is distinguished by prolonged disruption propagation, disruption existence, and high uncertainty. The purpose of this study was to investigate the role of R&D investment and firm performance in mediating the relationship between disruption risk and supply chain performance in Pakistani manufacturing industries and supply chain employees during the recovery phase of the COVID-19 pandemic via application of dynamic capability theory. Methodology: From July 21 to August 23, 2020, three hundred and eighteen employees from supply chains of manufacturing industries in Rawalpindi and Islamabad, Pakistan, participated in this cross-sectional online web-based survey. The four standard research scales were used to examine the research and development, disruption risk, firm, and supply chain performance. The response link was distributed to respondents via Facebook, WhatsApp, and email. The data was analyzed using structural equation modelling and a partial least squares technique in the study. Results: The study's findings suggest that disruption risk, research and development investment, and firm performance all improve supply chain performance, but the mediation effect is unsupported by the data. These measures help to plan a better supply chain in the face of disruption risk, and they provide one of the timely empirical conclusions on the role of R&D investment in mitigating risk disruptions and improving supply chain performance

Infect Disord Drug Targets ; 22(5): 12-21, 2022.
Article in English | MEDLINE | ID: covidwho-1606600


Coronavirus disease 2019 (COVID-19), which is a highly contagious viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a catastrophic effect on the world's demographics, resulting in more than 3.8 million deaths worldwide and establishing itself as the most serious global health crisis since the 1918 influenza pandemic. Several questions remain unanswered regarding the effects of COVID-19 disease during pregnancy. Although most infections are mild in high-risk populations, the severe disease frequently leads to intubation, intensive care unit admission, and, in some cases, death. Hormonal and physiological changes in the immune and respiratory systems, cardiovascular function, and coagulation may affect the progression of COVID-19 disease in pregnancy. However, the consequences of coronavirus infection on implantation, fetal growth and development, labor, and newborn health have yet to be determined, and, consequently, a coordinated global effort is needed in this respect. Principles of management concerning COVID-19 in pregnancy include early isolation, aggressive infection control procedures, oxygen therapy, avoidance of fluid overload, consideration of empiric antibiotics (secondary to bacterial infection risk), laboratory testing for the virus and co-infection, fetal and uterine contraction monitoring, prevention, and / or treatment of thromboembolism early mechanical ventilation for progressive respiratory failure, individualized delivery planning, and a team-based approach with multispecialty consultations. This review focuses on COVID-19 during pregnancy, its management, and the area where further investigations are needed to reduce the risk to mothers and their newborns.

COVID-19 , Pregnancy Complications, Infectious , Female , Global Health , Humans , Infant, Newborn , Pandemics/prevention & control , Pregnancy , SARS-CoV-2