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1.
Revue des Maladies Respiratoires Actualites ; 15(1):203-204, 2023.
Article in French | EMBASE | ID: covidwho-2182934

ABSTRACT

Declaration de liens d'interets: Les auteurs declarent ne pas avoir de liens d'interets. Copyright © 2022

2.
Revue des Maladies Respiratoires Actualites ; 15(1):7-8, 2023.
Article in French | EMBASE | ID: covidwho-2182899

ABSTRACT

Introduction: Les survivants de formes severes a critiques de COVID-19 peuvent presenter des sequelles fonctionnelles et radiologiques et des symptomes persistants a distance de l'episode aigu justifiant un suivi prolonge. L'objectif de l'etude est de determiner les trajectoires de recuperation respiratoire apres un COVID-19 severe, et les facteurs qui pourraient l'influencer. Methodes: Etude de cohorte prospective, multicentrique, longitudinale de patients adultes hospitalises pour COVID-19 severe (duree d'hospitalisation >= 7 j, debit d'oxygene >= 3 L) ou critique (intubation), evalues (clinique, TDM, EFR, test de marche, questionnaires de symptomes et de qualite de vie) 3 mois apres leur sortie de l'hopital, avec un suivi ulterieur conditionnel a 6 et 12 mois. Resultats: Au total, 486 participants ont ete inclus dans 13 hopitaux francais (age median : 61 ans;sexe feminin : 27 %) : 173 avaient necessite de l'oxygene seul, 96 un support ventilatoire non invasif (CPAP, OHD ou VNI) et 217 avaient ete intubes. Au total, 454 patients (93 %) ont ete evalues a 3 mois, 294 (60 %) et 163 (34 %) ont ete suivis respectivement jusqu'a 6 et 12 mois. Une dyspnee d'effort, un syndrome restrictif, un trouble de la diffusion et des anomalies radiologiques significatives ont ete observees respectivement dans 62 %, 33 %, 71 % et 57 % des cas a M3. En cas de suivi prolonge, la DLCO (% theo.) et la CVF (% theo.) augmentaient en moyenne de +4 points a M6 et respectivement de +6 points et +7 points a M12. Le sexe, l'indice de masse corporelle, les maladies cardiovasculaires ou respiratoires chroniques, l'immunodepression, l'etendue de la pneumonie pendant la phase aigue de la maladie et la duree prolongee (> 14 j) de ventilation mecanique invasive etaient associes a la DLCO a M3, mais pas a sa trajectoire ulterieure. Parmi 476 patients (97,9 %) ayant eu au moins une TDM thoracique au cours du suivi, 196 (41 %) avaient des sequelles significatives sur leur derniere imagerie. Le sexe, l'etendue de la pneumonie a la phase aigue, la duree de la ventilation mecanique invasive et la DLCO a M3 etaient independamment associes au resume des composantes physiques du SF-36, tandis que seul l'age etait associe au resume des composantes mentales du SF-36. Conclusion(s): Bien que la fonction respiratoire s'ameliore et que les anomalies radiologiques residuelles regressent jusqu'a 1 an apres l'episode aigu, une proportion importante des survivants de formes severes ou critiques de COVID-19 ont des sequelles radiologiques et fonctionnelles importantes et des symptomes residuels pouvant affecter leur qualite de vie et justifiant un tel suivi. Copyright © 2022

3.
ARS Medica Tomitana ; 27(2):89-93, 2021.
Article in English | EMBASE | ID: covidwho-2099035

ABSTRACT

The World Health Organization (WHO) declares COVID 19 pandemic in March 2020. Each pandemic wave had different clinical and biological characteristics, the expression of the disease being correlated with the dominant viral variant. Patients with COVID 19 have a pro-coagulant status, which predisposes them to thromboembolic complications. The current study aims to systematize the symptoms of COVID 19 and to highlight its relationship with the suspicion and confirmation of the diagnosis of pulmonary thromboembolism. We performed a descriptive retrospective study on patients with COVID 19 for a period of 4 months (September-December 2021). During this period, 183 were hospitalized with COVID 19 and 53 were enrolled in the study. Incidence of COVID 19 was 63% (33) in men and 37% for women. The average age of women was 68 years compared to men where the average age was 61 years. We observed a higher incidence of the disease in men in the 41-60 age group (39% of all men), while, in women, the most affected age group was 61-80 years (60% of all women). Pulmonary thromboembolism (PE) was diagnosed by pulmonary artery angiography, with an incidence of 57% in the study group affecting 60% of women and 55% of men. The symptoms are dominated by fever, cough and dyspnea. Fever was present in 65% of women and 55% of men, cough was present in 65% of women and 79% of men, while dyspnea involved 40% of women and 42% of men. In conclusion, PE was a common complication in COVID patients that contributed to adverse outcome and higher mortality. The symptoms were not specific to minor forms of the disease. Copyright © 2021 Authors. All rights reserved.

4.
ARS Medica Tomitana ; 27(2):78-82, 2021.
Article in English | EMBASE | ID: covidwho-2099033

ABSTRACT

Objective: The COVID 19 pandemic has been the biggest health problem in the last 2 years, exerting huge pressure on the global healthcare system. Studies showed a predisposition in men to develop more severe forms, with a higher mortality rate, in comparison to women. Also, men infected with SARS CoV2 would be at higher risk of hospitalization in acute intensive care units (ICU) with complications that could lead to death Methods: We conducted a retrospective cross-sectional study that included 177 hospitalized patients in a time frame of 18 months with SARS CoV2 infection confirmed by RT PCR testing in the Pneumology Department of the Clinical Hospital of Pneumophtisiology of Constanta, Romania. The information needed to conduct the study was gathered from the patient's general clinical observation sheet and included: the smoker/non-smoker status of the patient, age, symptoms associated with COVID19 infection, biological data, form of disease, treatment administered during hospitalization. Result(s): The study group included 177 patients, 42% of whom were women (82) and 54% were men (95), suggesting a higher incidence of SARS CoV2 infection in males. The most dominant symptom was cough in 62% cases of women and 56% cases of men. Females had a higher incidence of anosmia (11%) and ageusia (2%) compared to males (anosmia, ageuzia-1%). A higher predominance of women developing moderate forms compared to males. Severe forms were found in 22% of cases in women and 23% in men. Conclusion(s): It is inconclusive if male patients show a more severe evolution of COVID19 infection compared to females. Women have shown a predisposition to symptoms such as ageusia, anosmia and a more severe inflammatory syndrome. Copyright © 2021 Authors. All rights reserved.

5.
Espaces, Tourisme & Loisirs ; 358:118-125, 2021.
Article in French | CAB Abstracts | ID: covidwho-2046930

ABSTRACT

Accor, the European leader in the hotel industry, has been hit hard by the effects of the health crisis since March 2020. With the closure of hotels, hiring freeze, and deployment of partial unemployment, more than 220,000 employees have been affected by the consequences of the pandemic on the hotel group's activity. Beyond the emergency measures put in place, Accor has deployed an unprecedented aid system aimed at financially supporting its employees in the most difficult situation, and at welcoming the most vulnerable people within its establishments. At the same time, the group is already working on its recovery. It is in the process of certifying its hotels to guarantee optimum sanitary conditions, and is adapting a strategy focusing on the development of the lifestyle segment and on local customers.

8.
Revue des Maladies Respiratoires Actualités ; 14(1):108, 2022.
Article in French | ScienceDirect | ID: covidwho-1586701

ABSTRACT

Introduction Les infections virales respiratoires, dont l’infection à SARS-CoV-2, peuvent déclencher des symptômes respiratoires chez les patients souffrant de maladies respiratoires chroniques, entraînant des exacerbations et parfois des hospitalisations. Malgré le tropisme préférentiellement respiratoire du SARS-CoV-2, les études évaluant les maladies respiratoires chroniques comme facteurs de risque de forme critique de la COVID-19 sont controversées. L’objectif de cette étude était d’évaluer la prévalence de formes critiques de la COVID-19 chez les patients hospitalisés porteurs d’une maladie respiratoire chronique. Méthodes Cette étude rétrospective française bicentrique a inclus tous les patients hospitalisés du 15 mars au 30 juin 2020 pour motif respiratoire liée à la COVID-19, hors unités de soins intensifs et réanimation. Résultats Au total, 617 patients ont été inclus dont 125 présentant une maladie respiratoire chronique, principalement une bronchopneumopathie chronique obstructive (45 %) et un asthme (30 %) (Tableau 1). Le pourcentage de patients ayant obtenu un score de 6 ou plus sur l’échelle de progression clinique de l’Organisation mondiale de la santé 1 pendant leur hospitalisation était plus faible chez les patients atteints d’une maladie respiratoire chronique que dans la population générale (21,6 % contre 31,3 %, p=0,03 %). Parmi les patients porteurs d’une maladie respiratoire chronique, une température supérieure à 38°C à l’admission (OR 16,88 [IC 95 % 4,01–71,00]), une lymphopénie (OR 5,08 [1,25–20,72]), un traitement par pression positive continue (OR 4,46 [1,04–19,17]) et un âge élevé (OR 1,09 [1,02–1,16]) étaient associés à un risque accru d’atteindre un score de 6 ou plus. Conclusion Selon cette étude, les patients porteurs d’une maladie respiratoire chronique hospitalisés pour forme grave de la COVID-19 ont un risque plus faible de développer une forme critique de la maladie, en particulier les patients souffrant d’une broncho-pneumopathie chronique obstructive et d’un asthme. Des études prospectives pourraient permettre de confirmer nos résultats et d’éclaircir l’impact des traitements inhalés et notamment de la corticothérapie sur la sévérité des infections à SARS-CoV-2.

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