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1.
Chinese Journal of Bioprocess Engineering ; 20(6):583-596, 2022.
Article in Chinese | GIM | ID: covidwho-20244426

ABSTRACT

The global pandemic coronavirus pneumonia (COVID-19), the disease infected by the new coronavirus (SARS-CoV-2), is extremely contagious. It is mainly spread among people through respiratory droplets, aerosols, direct or indirect contact, fecal-oral transmission, and cold chain transportation. Especially, patients who are in the incubation period or have no obvious symptoms already have the ability to infect others. SARS-C0V-2 is a positive-sense single-stranded RNA virus, with a single linear RNA segment. Each SARS-CoV-2 virion is 60-140 mm in diameter. Like other coronaviruses, SARS-CoV-2 has four structural proteins, known as the spike (S), envelope(E), membrane (M), and nucleocapsid (N) proteins. To date, a variety of detection methods for the SARS-CoV-2 have been developed based on the virus structural basis and 'etiological characteristics, which would provide an effective guarantee for the diagnosis of COVID-19 patients and the control of the epidemic. In order to help for the early diagnosis and prevention of COVID-19, the pathogenic characteristics and recent progresses of detection base on nucleic acid, immunology and biosensors of the SARS-CoV-2 are reviewed in this paper.

2.
Chinese Journal of Bioprocess Engineering ; 20(6):583-596, 2022.
Article in Chinese | GIM | ID: covidwho-2326961

ABSTRACT

The global pandemic coronavirus pneumonia (COVID-19), the disease infected by the new coronavirus (SARS-CoV-2), is extremely contagious. It is mainly spread among people through respiratory droplets, aerosols, direct or indirect contact, fecal-oral transmission, and cold chain transportation. Especially, patients who are in the incubation period or have no obvious symptoms already have the ability to infect others. SARS-C0V-2 is a positive-sense single-stranded RNA virus, with a single linear RNA segment. Each SARS-CoV-2 virion is 60-140 mm in diameter. Like other coronaviruses, SARS-CoV-2 has four structural proteins, known as the spike (S), envelope(E), membrane (M), and nucleocapsid (N) proteins. To date, a variety of detection methods for the SARS-CoV-2 have been developed based on the virus structural basis and 'etiological characteristics, which would provide an effective guarantee for the diagnosis of COVID-19 patients and the control of the epidemic. In order to help for the early diagnosis and prevention of COVID-19, the pathogenic characteristics and recent progresses of detection base on nucleic acid, immunology and biosensors of the SARS-CoV-2 are reviewed in this paper.

3.
Shengwu Jiagong Guocheng = Chinese Journal of Bioprocess Engineering ; 20(6):583, 2022.
Article in English | ProQuest Central | ID: covidwho-2170083

ABSTRACT

The global pandemic coronavirus pneumonia(COVID-19),the disease infected by the new coronavirus(SARS-CoV-2),is extremely contagious.It is mainly spread among people through respiratory droplets, aerosols, direct or indirect contact, fecal-oral transmission, and cold chain transportation.Especially, patients who are in the incubation period or have no obvious symptoms already have the ability to infect others.SARS-CoV-2 is a positive-sense single-stranded RNA virus, with a single linear RNA segment.Each SARS-CoV-2 virion is 60-140 nm in diameter.Like other coronaviruses, SARS-CoV-2 has four structural proteins, known as the spike(S), envelope(E),membrane(M),and nucleocapsid(N) proteins.To date, a variety of detection methods for the SARS-CoV-2 have been developed based on the virus structural basis and etiological characteristics, which would provide an effective guarantee for the diagnosis of COVID-19 patients and the control of the epidemic.In order to help for the early diagnosis and prevention of COVID-19,the pathogenic characteristics and recent progresses of detection base on nucleic acid, immunology and biosensors of the SARS-CoV-2 are reviewed in this paper.

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