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Residual Lung Abnormalities Following COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID Study

Stewart, I.; Jacob, J.; George, P. M.; Molyneaux, P. L.; Porter, J. C.; Allen, R. J.; Aslani, S.; Baillie, J. K.; Barratt, S. L.; Beirne, P.; Bianchi, S. M.; Blaikley, J. F.; Chalmers, J. D.; Chambers, R. C.; Chaudhuri, N.; Coleman, C.; Collier, G.; Denneny, E. K.; Docherty, A.; Elneima, O.; Evans, R. A.; Fabbri, L.; Gibbons, M. A.; Gleeson, F. V.; Gooptu, B.; Greening, N. J.; Guillen Guio, B.; Hall, I. P.; Hanley, N. A.; Harris, V.; Harrison, E. M.; Heightman, M.; Hillman, T. E.; Horsley, A.; Houchen-Wolloff, L.; Jarrold, I.; Johnson, S. R.; Jones, M. G.; Khan, F.; Lawson, R.; Leavy, O.; Lone, N.; Marks, M.; McAuley, H.; Mehta, P.; Parekh, D.; Piper Hanley, K.; Plate, M.; Pearl, J.; Poinasamy, K.; Quint, J. K.; Raman, B.; Richardson, M.; Rivera-Ortega, P.; Saunders, L.; Saunders, R.; Semple, M. G.; Sereno, M.; Shikotra, A.; Simpson, A. J.; Singapuri, A.; Smith, D. J.; Spears, M.; Spencer, L. G.; Stanel, S.; Thickett, D.; Thompson, A. A. R.; Thorpe, M.; Walsh, S. L.; Walker, S.; Weatherley, N. D.; Weeks, M.; Wild, J. M.; Wootton, D. G.; Brightling, C. E.; Ho, L. P.; Wain, L. V.; Jenkins, R. G..

American Journal of Respiratory & Critical Care Medicine ; 01:01, 2022.

Article in English | MEDLINE | ID: covidwho-2153229

ABSTRACT

RATIONALE: Shared symptoms and genetic architecture between COVID-19 and lung fibrosis suggests SARS-CoV-2 infection may lead to progressive lung damage.

S75 Hyperpolarised 129-xenon MRI in differentiating between fibrotic and inflammatory interstitial lung disease and assessing longitudinal change

Eaden, J. A.; Collier, G. J.; Norquay, G.; H-F, Chan, Hughes, P. J. C.; Weatherley, N. D.; Rajaram, S.; Swift, A.; Leonard, C. T.; Skeoch, S.; Chaudhuri, N.; Parker, G. J. M.; Bianchi, S. M.; Wild, J. M..

Thorax ; 76(Suppl 1):A46-A47, 2021.

Article in English | ProQuest Central | ID: covidwho-1050407

ABSTRACT

S75 Figure 1Difference between the fibrotic and inflammatory groups in mean 129Xe ADC (a) and LmD (b) at baseline study visit[Figure omitted. See PDF]Conclusions129Xe DW-MRI could have a role in differentiating changes in the airway microstructure between fibrotic and inflammatory ILD. 129Xe RBC:TP has sensitivity to longitudinal change with a decline in gas exchange observed in the fibrotic group but not in the inflammatory group.

ABSTRACT

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