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The Editor-in-Chief and the publisher have retracted this article. The article was submitted to be part of a guest-edited issue. An investigation by the publisher found a number of articles, including this one, with a number of concerns, including but not limited to compromised editorial handling and peer review process, inappropriate or irrelevant references or not being in scope of the journal or guest-edited issue. Based on the investigation's findings the Editor-in-Chief therefore no longer has confidence in the results and conclusions of this article. Author Mohammad Khishe disagrees with the retraction. The other authors have not responded to correspondence regarding this retraction. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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This study aims to investigate how consumer's use of online food delivery (OFD) services is driven by its self-protective nature. Drawing on protection motivation theory, the unified theory of use and acceptance of technology, and diffusion of innovation theory, an integrated model was tested with 1,000 empirical data points to explain consumers' OFD use during the pandemic. Results confirmed the self-protective nature of OFD use by uncovering a significant positive effect of fear of COVID-19 on consumers' OFD ordering frequency. Perceived vulnerability contributed more strongly to an individual's fear of COVID-19 than perceived severity in dining activities. These findings theoretically expand the current understanding of OFD services and provide practical implications for OFD platforms, restaurateurs, and governments.
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In recent years, the novel corona virus pandemic is raging around the world, and the safety of home environment and public environment has become the focus of people's attention [2]. Therefore, the research on disinfection robot has become one of the important directions in the field of machinery and artificial intelligence. This paper proposes a robot with the STM32 MCU as the core of disinfection, and is equipped with a variety of sensors and a camera vision, has the original cloud service management platform, the remote deployment of navigation, based on visual SLAM to realize high precision navigation and positioning, can realize to indoor environment autonomously route planning, automatic obstacle avoidance checking, disinfection, epidemic prevention function, at the same time can pass Bit computer software realizes remote control of robot, which has great development potential. © 2022 ACM.
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A substantive body of work in project studies argues that an "information flow" lens is very useful in exploring the project management of construction. This paper posits that this is even more applicable to disaster construction projects and, furthermore, lean information flow may play a role in swiftly delivering the disaster construction project. The paper uses the qualitative empirics of the delivery of the UK's Covid surge hospital projects to demonstrate that lean information flows were employed in these projects and assisted in enabling delivery at speed. The paper also describes the autopoietic governance conditions that are necessary for lean information flows to flourish in disaster construction projects and the role that trust may play in these conditions. It warns against some of the drawbacks in enabling lean communication through autopoietic governance.
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Guided by Community of Inquiry (Garrison and Vaughan, Blended learning in higher education: Framework, principles, and guidelines. Jossey-Bass Publishers, 2008), this study investigated faculty's cognitive, social, and teaching presences in teaching Chinese as a foreign language classroom during emergency remote teaching (ERT) necessitated by the COVID-19 pandemic during the spring semester of 2020. The study collected data from five videoconferencing interviews with five faculty participants. The five participants, purposefully sampled, taught Chinese language classes across varying proficiency levels from five different four-year college institutions in the United States. The study analyzed the engagement strategies the participants employed in organizing their social, cognitive, and teaching presences. It further suggests pedagogical implications and future research for language instructors, teacher education programs, and university administrators to consider. © The Editor(s) (if applicable) and The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022.
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Allogeneic hematopoietic stem cell transplantation (allo- HSCT) has traditionally involves administering fresh peripheral blood or bone marrow stem cells. At onset of the COVID-19 pandemic in March 2020, the National Marrow Donor Program (NDMP) mandated cryopreservation of all unrelated peripheral blood stem cell (PBSC) products to prevent interruptions in transplant plans by donor COVID-19 infection after recipient's start of conditioning chemotherapy. Since the lifting of this mandate, many centers have continued to cryopreserve grafts prior to initiation of conditioning, but the longer-term clinical outcomes of this practice including chronic graft versus host disease (cGVHD) rates of patients receiving cryopreserved stem cells have not been previously well described. Prior work has raised concern for a deleterious effect of cryopreservation on overall survival and non-relapse mortality (PMID: 33865804). However, heterogeneity in the patient population and reason for cryopreservation suggest that further study is needed to assess these outcomes. Here we report our single-institution experience of clinical outcomes using cryopreserved versus fresh URD PBSCs for allo-HSCT. We examined long-term outcomes in 387 patients who received unrelated donor (URD) PBSCs (136 cryopreserved, 251 fresh) between January 1, 2019 and July 31, 2021. The cohorts had similar baseline characteristics including donor/recipient age/sex, disease, conditioning regimen/intensity, and GVHD prophylaxis regimens. Two-year OS, PFS, relapse, NRM, and acute GVHD rates were not different between recipients of fresh versus cryopreserved PBSCs. Strikingly, 2-year incidence of cGVHD (28% vs 52%, p=0.00001) and moderate/severe cGVHD (9% vs 24%, p=0.00016) was substantially lower in recipients of cryopreserved PBSCs compared to fresh, respectively (Figure 1). This difference was only noted in patients receiving a GVHD prophylaxis regimen without post-transplantation cyclophosphamide (PTCY) (no PTCY 2-year cGVHD incidence cryopreserved vs fresh: 29% vs 57%, p=0.000016), moderate/severe cGVHD 16% vs 34%, p=0.0006) (Figure 2). For patients receiving a PTCY-containing GVHD prophylaxis regimen, there was no difference in cGVHD incidence (cGVHD cryopreserved vs fresh: 24% vs 27%, p=0.56, moderate/severe cGVHD 7% vs 9.3%, p=0.3, Figure 3). (Figure Presented) (Figure Presented) (Figure Presented) While survival and relapse rates are not different, cryopreservation is associated with a marked reduction in cGVHD rates in the setting of non-PTCy based GVHD prophylaxis. Larger multicenter or registry analyses are needed to confirm these observations and may prompt a re-assessment of the role of cryopreservation of stem cell products in clinical practice. If confirmed, it will be critical to understand the immunologic consequences of cryopreservation and how they might influence the clinical impact on chronic GVHDCopyright © 2023 American Society for Transplantation and Cellular Therapy
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In the era of "Post-epidemic" and "Dual-carbon targets", the focus of research on China's carbon trading market has changed from basic framework design to problem solving and development paths in the process of practice. Foreign carbon trading markets have developed for many years, and have experienced the financial crisis and the impact of the coronavirus epidemic. By analyzing the important problems and countermeasures encountered in the process of carbon trading market by representative organizations such as EU, USA, New Zealand, Korea and Japan, the valuable experience and reference significance of foreign carbon trading practice were summarized. At the same time, comparing the similarities and differences between Chinese and foreign carbon trading national conditions, and taking into account the current development of China's carbon trading market, this paper put forward some carbon trading strategies with Chinese characteristics and absorbing foreign advanced experience, such as choosing appropriate emission caps, balancing regulation, formulating price stabilization mechanism, and leaving interfaces for international cooperation. © 2023 Research Institute of Petroleum Processing, SINOPEC. All rights reserved.
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Desktop as a Service (DaaS) has become widely used by enterprises. In 2020, the use of DaaS increased dramatically due to the demand to work remotely from home during the COVID-19 pandemic. The DaaS market is expected to continue growing rapidly [1]. The quality of experience (QoE) of a DaaS service has been one of the main factors to enhance DaaS user satisfaction. To ensure user QoE, the amount of cloud computation resources for a DaaS service must be appropriately designed. We propose an Intent-driven DaaS Management (IDM) framework to autonomously determine the cloud-resource-amount configurations for a given DaaS QoE requirement. IDM enables autonomous resource design by ing the knowledge about the dependency between DaaS workload, resource configuration, and performance from previous DaaS performance log data. To ensure the IDM framework's applicability to actual DaaS services, we analyzed five main challenges in applying the IDM framework to actual DaaS services: identifying the resource-design objective, quantifying DaaS QoE, addressing low log data availability, designing performance-inference models, and addressing low resource variations in the log data. We addressed these challenges through detailed designing of IDM modules. The effectiveness of the IDM framework was assessed from the aspects of DaaS performance-inference precision, DaaS resource design, and time and human-resource cost reduction. © 2022 Copyright held by the owner/author(s). Publication rights licensed to ACM.
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Purpose: The high-pressure nature of the construction industry, along with the COVID-19 pandemic, triggered abusive supervision (i.e. workplace bullying and incivility behaviour) that has diminished workers' well-being. However, despite the growing prevalence in practice and increasing concern in academia, abusive supervision remains largely unexplored by construction management scholars. This study aims to fill the gap in the current literature by analysing the effects of abusive supervision on construction workers' well-being, the mediating role of guanxi closeness and the moderating role of trust in the manager. Design/methodology/approach: A questionnaire survey was completed by 258 Chinese construction workers. The data underwent mediation and moderation analyses using PROCESS macro 3.5 for SPSS. Findings: The results revealed that managers' abusive supervision reduced construction workers' well-being at work and in life. Guanxi closeness between manager and workers mediated the relationship between managers' abusive supervision and construction workers' well-being. Additionally, trust in managers moderated the mediating effect of guanxi closeness. This study further revealed that the emotional connection between construction managers and workers, such as expressive guanxi closeness and affective-based trust, is important in handling the impact of abusive supervision on the workers. Practical implications: The findings of this study provide support for recent calls to address negative manager behaviours such as abusive supervision in construction management. They aid the development of a more comprehensive internal mechanism that considers the influence of guanxi closeness on the outcomes of abusive supervision by managers at construction sites. Additionally, interventions that develop trust in managers may be particularly effective in alleviating the tension of abusive supervision. More attention should be paid to managers' emotional connections in daily construction project management. Originality/value: Rather than concentrate on positive leadership, this study shifts the focus to negative leadership in construction project management by identifying abusive supervision as a negative primary antecedent of workers' well-being. While prior research has highlighted how negative manager behaviours affect workers' well-being from the conservation of resources theory (COR) perspective, this study is the first, to the authors' knowledge, to adopt a social exchange theory perspective by introducing guanxi closeness as a mediator. It contributes to a greater understanding of how trust in the manager alleviates the negative effect of the person's abusive supervision on construction workers. © 2023, Emerald Publishing Limited.
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The use of the internet in education has been greatly encouraged by the COVID-19 epidemic. Studying students' internet-specific epistemic beliefs (ISEB) and possible correlates would benefit online teaching and learning. However, little research has been conducted in this field. Therefore, we investigated the current status of ISEB among college students and considered the impact of self-regulated learning (SRL) and e-academic dishonesty (e-AD) on ISEB. A survey research method and convenience sampling were employed. A total of 538 Chinese college students completed the self-reported questionnaire. Our results indicate that although no significant differences were found in ISEB in terms of gender and academic major, students with different backgrounds also differed in e-AD experience and SRL. Three dimensions of ISEB were negatively correlated with SRL, while one had a significant positive correlation. In addition, the latter dimension of ISEB was negatively correlated with e-AD. Finally, SRL and e-AD jointly significantly predicted students' different ISEB, with explanatory power ranging from 14% to 36%. Study techniques of SRL were common predictors that could negatively predict the certainty, simplicity, and source of ISEB and positively predict justification. Based on the results, specific methods for schools, teachers and librarians to enhance students' ISEB are provided. © 2023
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Importance: The COVID-19 pandemic has played a role in increased use of virtual care in primary care. However, few studies have examined the association between virtual primary care visits and other health care use. Objective: To evaluate the association between the percentage of virtual visits in primary care and the rate of emergency department (ED) visits. Design, Setting, and Participants: This cross-sectional study used routinely collected administrative data and was conducted in Ontario, Canada. The sample comprised family physicians with at least 1 primary care visit claim between February 1 and October 31, 2021, and permanent Ontario residents who were alive as of March 31, 2021. All residents were assigned to physicians according to enrollment and billing data. Exposure: Family physicians' virtual visit rate was the exposure. Physicians were stratified by the percentage of total visits that they delivered virtually (via telephone or video) during the study period (0% [100% in person], >0%-20%, >20%-40%, >40%-60%, >60%-80%, >80% to <100%, or 100%). Main Outcomes and Measures: Population-level ED visit rate was calculated for each stratum of virtual care use. Multivariable regression models were used to understand the relative rate of patient ED use after adjusting for rurality of practice, patient characteristics, and 2019 ED visit rates. Results: Data were analyzed for a total of 13â¯820 family physicians (7114 males [51.5%]; mean [SD] age, 50 [13.1] years) with 12â¯951â¯063 patients (6 714 150 females [51.8%]; mean [SD] age, 42.6 [22.9] years) who were attached to these physicians. Most physicians provided between 40% and 80% of care virtually. A higher percentage of the physicians who provided more than 80% of care virtually were 65 years or older, female individuals, and practiced in big cities. Patient comorbidity and morbidity were similar across strata of virtual care use. The mean (SD) number of ED visits was highest among patients whose physicians provided only in-person care (470.3 [1918.8] per 1000 patients) and was lowest among patients of physicians who provided more than 80% to less than 100% of care virtually (242.0 [800.3] per 1000 patients). After adjustment for patient characteristics, patients of physicians with more than 20% of visits delivered virtually had lower rates of ED visits compared with patients of physicians who provided more than 0% to 20% of care virtually (eg, >80% to <100% vs >0%-20% virtual visits in big cities: relative rate, 0.77%; 95% CI, 0.74%-0.81%). This pattern was unchanged across all rurality of practice strata and after adjustment for 2019 ED visit rates. In urban areas, there was a gradient whereby patients of physicians providing the highest level of virtual care had the lowest ED visit rates. Conclusions and Relevance: Findings of this study show that patients of physicians who provided a higher percentage of virtual care did not have higher ED visit rates compared with patients of physicians who provided the lowest levels of virtual care. The findings refute the hypothesis that family physicians providing more care virtually during the pandemic resulted in higher ED use.
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COVID-19 , Pandemics , Male , Humans , Female , Middle Aged , Adult , Ontario/epidemiology , Physicians, Family , Cross-Sectional Studies , COVID-19/epidemiology , Emergency Service, HospitalABSTRACT
Plant bioreactors have been the central part of molecular pharming. Vaccines, antibodies and functional foods produced by plant bioreactors with the benefits of cost-effectiveness, high scalability, rapid production, enabling post-translational modification, and no harmful pathogens contamination are increasingly accepted by the public. In February 2022, Health Canada approved the world's first plant-derived human vaccine Covifenz® for the prevention and treatment of COVID-19, marking the advent of the era of molecular pharming represented by plant bioreactors. This paper elaborates the development history of plant bioreactors, with the main host species representatives of leafy plants and seed plants, the stable and transient expression systems construction for various applications, as well as the enhancement strategies through promoter and codon optimization, "humanization” of glycosylation process, inhibition of gene silencing and protease activity, and also summarize the application of plant-derived protein products, which aim to provide a theoretical and application basis for the development of plant bioreactors. © 2023, China Biotechnology Press. All rights reserved.
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Background: Coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has imposed great medical and economic burdens on human society, and nanotechnology is a promising technique for managing the ongoing COVID-19 pandemic. To drive further studies on anti-COVID-19 nanotechnology, this paper provides an analysis, from a bibliometric perspective, of the intersection of nanotechnology and SARS-CoV-2/COVID-19. Methods: We analyzed the 2585 publications on nanotechnology and SARS-CoV-2/COVID-19 included in the Web of Science Core Collection from January 2019 to March 2022 to determine the bibliometric landscape. The basic bibliometric characteristics are summarized in this article. Results: Our bibliometric analysis revealed that the intersection between nanotechnology and SARS-CoV-2/COVID-19 is a cutting-edge field in the science community and that the related studies were multidisciplinary in nature. Studies on the structural basis of SARS-CoV-2, SARS-CoV-2 detection assays, and mRNA vaccines against COVID-19 provided the development foundation for this field. Conclusions: The current research focuses are the development of nanomaterial-based vaccines and SARS-CoV-2 detection methods, and the design of nanomedicines carrying SARS-CoV-2 inhibitors is a relatively burgeoning frontier. In summary, this bibliometric analysis of the intersection of nanotechnology and SARS-CoV-2/COVID-19 highlights the current research focuses of this field to inspire future studies on anti-COVID-19 nanotechnologies. © 2022
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In the era of "Post-epidemic" and "Dual-carbon targets", the focus of research on China's carbon trading market has changed from basic framework design to problem solving and development paths in the process of practice. Foreign carbon trading markets have developed for many years, and have experienced the financial crisis and the impact of the coronavirus epidemic. By analyzing the important problems and countermeasures encountered in the process of carbon trading market by representative organizations such as EU, USA, New Zealand, Korea and Japan, the valuable experience and reference significance of foreign carbon trading practice were summarized. At the same time, comparing the similarities and differences between Chinese and foreign carbon trading national conditions, and taking into account the current development of China's carbon trading market, this paper put forward some carbon trading strategies with Chinese characteristics and absorbing foreign advanced experience, such as choosing appropriate emission caps, balancing regulation, formulating price stabilization mechanism, and leaving interfaces for international cooperation. © 2023 Research Institute of Petroleum Processing, SINOPEC. All rights reserved.
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The filtration efficiency deterioration over operating time due to exposure to particles, organic solvents and other factors is an obvious defect of electret filter, especially during the coronavirus pandemic. Electrostatic enhanced method has been proposed as a promising way to improve the filtration efficiency and service time of electret filters without increasing the pressure drop. In this work, the effect of discharge electrode structure and operation mode of the electrostatic enhanced structure(EES) on the filtration efficiency of commercial pleated electret filters were studied firstly, then the EES was installed in a special designed prototype air purifier, two key indicators of air purifiers(clean air delivery rate (CADR) and cumulate clean mass (CCM)) were tested to evaluate the actual performance improvement of electret filters by the electrostatic enhanced method. It was found that the discharge electrode structure had significant influence on the filtration efficiency and multi-wire array electrode was more suitable for the discharge electrode to pleated filter to ground mesh structure used in this paper. The decayed electrostatic charges of pleated electret filter cannot be recharged again through the EES in actual operation condition. The filtration efficiency improvement of the test pleated electret filters was dominantly contributed by particle charging. The filter polarizing induced by the external electric field was helpful in increasing the filtration efficiency when the particles were charged while its effect on uncharged particles was almost negligible. Besides, the actual performance of the prototype air purifier indicated that the EES can alleviate the filtration efficiency deterioration of test electret filters and extend the service life of H11 and H13 filters by more than 3 and 1.5 times respectively according to the CCM test results. © 2023 IOP Publishing Ltd.
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We report a point-of-care (POC) device for simultaneous detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A viruses. The device carries out sample preparation using ball-based valves for sequential delivery of reagents. A microfluidic paper-based analytical device (µPAD) in the detection unit enables RNA isolation and enrichment, followed by reverse transcription loop-mediated isothermal amplification (RT-LAMP) and colorimetric detection. The device integrates all the necessary steps for the sample preparation, including virus lysis, RNA enrichment and purification of two virus samples. The device enabled simultaneous detection of SARS-CoV-2 and Influenza A N1H1 viruses in 50 min., with limit of detection of 2 and 6 genome equivalents (GEs), respectively. The device was also capable of detecting environmental sample of the two viruses. Copyright © 2022 by ASME.
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The Association of Southeast Asian Nations (ASEAN) is an attractive tourist destination with diverse and unique experiences, in which Vietnam is considered one of the most famous destinations in this region. Quality evaluations and strategies for attracting international tourists are being thoroughly researched. However, the COVID-19 pandemic has had the most significant impact on the tourism industry, which has suffered greatly. Therefore, the recovery and expansion of international tourism necessitate the employment of tourism-related businesses and service sector workers. Extensive research must be conducted to identify solutions and new directions to recover the international tourist market's growth as quickly as possible. This study identifies the factors that influence the destination of international visitors visiting Vietnam after the COVID-19 pandemic by modifying and evaluating the scales of the theoretical model. Using the convenience sampling technique, data were collected through interviews with 208 international visitors, with 29 observed variables. Using SPSS 22.0, five factors influencing international visitors' decisions to visit Vietnam were revealed: tourist motivation, tourist attitude, destination image, social media, and environmental quality. Finally, the authors provide policy recommendations to enhance the allure and viability of Vietnam's tourism following the effects of the COVID-19 pandemic. This study's outcome is intended to establish the importance of the many variables influencing the choice of destination for international visitors. © 2022 by the authors.
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This study applies time-series analysis to observe investor sentiment in the tourism stock market. We infer that investor sentiment positively affects the capital flows to illustrate the behavioral finance in the tourism stock market. The vector autoregression and autoregressive-moving-average models of time-series analysis are adopted to analyze individual and overall capital flows of herding behavior. The empirical study collected quarterly data on 45 tourism-related stocks in China from 2018 to 2020. Results reaffirm that investor sentiment causes irrational investment and strong fluctuations of capital flows, including those during the Coronavirus 2019 pandemic. In practice, the overreaction of tourism-related stocks is discovered in the tourism market that requires long-term resilience. Theoretically, the rational capital asset pricing model needs adjustments with the sentiment factor based on behavioral finance theory. © 2022 Elsevier B.V.
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As a theoretically rigorous and accurate method, FEP-ABFE (Free Energy Perturbation-Absolute Binding Free Energy) calculations showed great potential in drug discovery, but its practical application was difficult due to high computational cost. To rapidly discover antiviral drugs targeting SARS-CoV-2 Mpro and TMPRSS2, we performed FEP-ABFE–based virtual screening for ∼12,000 protein-ligand binding systems on a new generation of Tianhe supercomputer. A task management tool was specifically developed for automating the whole process involving more than 500,000 MD tasks. In further experimental validation, 50 out of 98 tested compounds showed significant inhibitory activity towards Mpro, and one representative inhibitor, dipyridamole, showed remarkable outcomes in subsequent clinical trials. This work not only demonstrates the potential of FEP-ABFE in drug discovery but also provides an excellent starting point for further development of anti-SARS-CoV-2 drugs. Besides, ∼500 TB of data generated in this work will also accelerate the further development of FEP-related methods. © The Author(s) 2022.