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Journal of Materials Chemistry A ; : 13, 2022.
Article in English | Web of Science | ID: covidwho-1626160


As important personal protective equipment (PPE), face masks play a key role in self-protection during disastrous pandemics caused by the COVID-19 virus and other respiratory viruses. On the other hand, the massive utilization of disposable face masks creates big challenges not only in recycling and sterilizing the used face masks, but also in terms of plastic pollution and resource-saving. So, the development of self-sanitizing reusable face masks is highly imperative. We report herein a covalent organic framework (COF)-based face mask. In this regard, a Ag NP loaded and quinolinecarboxylic acid-linked nanoscale porphyrin COF composite of Ag@DhaTph-COOH is constructed by a three-component one-pot in situ Doebner reaction and sequential solution impregnation and NaBH4 reduction. After mixing the hydroxyl-enriched COF NPs with isocyanate-terminated polyurethane oligomers, the obtained covalently cross-linked COF-dispersion is sprayed onto the outer layer of the non-woven PET fabric surface to yield a face mask with the deposited Ag@DhaTph-COOH NPs. Our face mask is reusable and exhibits solar-powered self-sanitizing ability with excellent antibacterial and antiviral performance via a triple-modal chemo/PDT/PTT synergistic treatment under natural sunlight irradiation.

Zhonghua Nei Ke Za Zhi ; 59(8): 588-597, 2020 Aug 01.
Article in Chinese | MEDLINE | ID: covidwho-595773


Coronavirus disease 2019 (COVID-19) can cause great damage to the elderly patients and lead to high mortality. The clinical presentations and auxiliary examinations of the elderly patients with COVID-19 are atypical, due to the physiological ageing deterioration and basal pathological state. The treatment strategy for the elderly patients has its own characteristics and treatment protocol should be considered accordingly. To improve the diagnosis, treatment, and prevention of COVID-19 in the elderly, the Expert Committee of Geriatric Respiratory and Critical Care Medicine, China Society of Geriatrics established the "Expert consensus for the diagnosis, treatment, and prevention of coronavirus disease 2019 in the elderly" . We focused on the clinical characteristics and key points for better treatment and prevention of COVID-19 in the elderly. (1) For diagnosis, atypical clinical presentation of COVID-19 in the elderly should be emphasized, which may be complicated by underlying disease. (2) For treatment, strategy of multiple disciplinary team (mainly the respiratory and critical care medicine) should be adopted and multiple systemic functions should be considered. (3) For prevention, health care model about integrated management of acute and chronic diseases, in and out of hospital should be applied.

COVID-19 , Aged , China , Consensus , Humans , SARS-CoV-2