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EuropePMC; 2022.
Preprint in English | EuropePMC | ID: ppcovidwho-332736


Copper death is a newly identified unique form of regulated apoptosis. Studies suggest that it may be the mode of apoptosis in cancer cells. Therefore, copper death-related genes may become therapeutic targets for hepatocellular carcinoma. Also, SARS-CoV-2 is currently the most widely spread virus in the world with no curative drug available. Liver cancer is the most common fatal malignancy in the world. By the time a patient presents to the clinic, liver cancer has progressed to an advanced stage and the prognosis is often poor. In this study, the prognosis of patients with liver cancer when they get SARS-CoV-2 was predicted by examining the relationship between SARS-CoV-2, copper death and liver cancer.

Front Oncol ; 11: 719554, 2021.
Article in English | MEDLINE | ID: covidwho-1533689


Peritoneal lymphomatosis is extremely rare and associated with poor prognosis. Most practitioners only pay more attention to peritoneal carcinomatosis. However, peritoneal lymphomatosis can be neglected and misdiagnosed. We report a teenager with 10 days of abdominal distension and pain accompanied by computed tomography scan suggesting diffuse thickening of the peritoneum and omentum and abdominopelvic effusion. Tuberculous peritonitis and peritoneal carcinomatosis were initially suspected. However, it was finally confirmed as non-Hodgkin's B-cell lymphoma by omentum biopsies. He achieved complete remission after chemotherapy and autologous stem cell transplantation. But unfortunately, he suffered a relapse and died 10 months after diagnosis. Following a review of the literature, it can be concluded that the discovery of lymphomatosis in peritoneum is a rare finding. Lymphoma should be considered in the differential diagnosis of unexplained peritoneal thickening on computed tomography, and this case emphasizes the importance of early pathological diagnosis to make sure that the right treatment can be started opportunely.