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Medical Journal of Wuhan University ; 41(4):537-541, 2020.
Article | COVIDWHO | ID: covidwho-616548

ABSTRACT

Objective: To investigate clinical features and the morbidity of patients with severe coronavirus disease 2019 (COVID-19) complicated with acute kidney injury (AKI) Methods: We enrolled 62 patients with severe COVID-19 admitted to Intensive Care Unit (ICU) from January 8, 2020 to February 24, 2020 in Zhongnan Hospital of Wuhan University The demographic data, symptoms, physical signs, comorbidities, laboratory results and related treatment of these patients were recorded AKI was defined according to the diagnostic criteria of KDIGO guideline in 2012 Results: The mean age of 62 patients was 62 9 years old, and 39 (62 9%) were male 10 patients (16 1%) were presumed to be infected in hospital, and 52 (83 9%) were community infection cases 18 (29 0%) patients occurred AKI during their ICU stay and 9 of them received continuous renal replacement therapy (CRRT) All patients with severe COVID-19 received respiratory support, 48 3% of them received invasive mechanical ventilation, and the respiratory supporting level of AKI patients was higher than that of non-AKI patients Up to Feb 24, 14 severe COVID-19 patients died during their hospital stay and the overall mortality was 22 6% Mortality of patients with AKI was 44 4% Conclusion: The risk of AKI in patients with severe COVID-19 is high and the prognosis is poor, although organ supporting technologies were adopted © 2020, Editorial Board of Medical Journal of Wuhan University All right reserved

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