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Fudan University Journal of Medical Sciences ; 49(4):537-547, 2022.
Article in Chinese | Scopus | ID: covidwho-2055554


Objective To understand the status of family services and residents’demands for services in Shanghai in order to construct and improve the key elements of family services in public health events. Methods We used a combining method of individual in-depth interviews and focused group interviews. The informants were domestic and foreign experts in public health, health services, education, safety, etc., community workers and residents. The interview questions were as follow:problems in family services, residents’demands and suggestions for family services, etc. Results We found 7 major family services problems in Shanghai’s response to public health events:The boundary of authorities and responsibilities were not clearly defined between the upper and lower departments. The team construction of public health professions at the community level was flawed. There were miscommunications between upper and lower medical institutions during the epidemic outbreaks. Residents were not aware of the available family services provided by their communities. Unnoticed insanitary spots still existed in public spaces, and the maintenance of residential emergence equipment needs to be strengthened. The public opinion guidance required further strengthening, and the elderly people lack an effective medium for information acquisition. The emergency plan of closed management to solve practical problems after Shanghai’s COVID lockdown was insufficient. The residents’demands included the following 6 aspects:comprehensive family services, supply and guarantee of basic living materials and special materials, professionals providing family services as a means of support, emergency medical services, receiving psychological intervention and understanding knowledge of mental health, security of food and food supply chain security. Conclusion ‘Government led’‘cross-border cooperation’‘clear executive body’and ‘based on the needs of residents’were key factors. Therefore, we suggest family services are included in the normalizing construction of government. © 2022 Fudan University. All rights reserved.

Annals of the Rheumatic Diseases ; 81:1685, 2022.
Article in English | EMBASE | ID: covidwho-2009040


Background: Novel Coronavirus pneumonia 2019 (COVID-19) is a systemic infectious disease with prominent involvement of the respiratory tract, due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[1]. Systemic lupus erythematosus is charcterized by an aberrant immune response with the presence of circulating autoantibodies, lymphopenia, and proinfammatory[2]. They are immune-compromised and vulnerable to infections with immune-suppressants treatment. However, data regarding the impact of COVID-19 pandemic in patients with SLE and drug use were relatively scarce. Objectives: The prevalence of COVID-19 in SLE patients was estimated by means of meta-analysis, and the effect of the use of anti-rheumatic drugs on the clinical outcome of SLE patients with COVID-19 was investigated. Methods: Cross-sectional investigations and case series on SLE and COVID-19 published by CBM, CNKI, China Science and Technology Journal Database, Wan Fang Data, PubMed, Embase, Web of Science, Cochrane Library and Medline from its establishment to November 10, 2021 were searched. Random effects model was used to pool data. Heterogeneity and risk of bias was examined with I-squared index (I2) statistic. Inconsistency was evaluated by using the I2. Egger tests were used for the evaluation of potential publication bias (STATA v.12.0). Results: A total of 14 studies comprising 5365 patients were identifed (Table 1). Overall prevalence of COVID-19 in SLE patients was 1.5% (95%CI: 1.2%-1.8%). Eight of the studies included patients who used hydroxychloroquine as part of their treatment regimen, with 29.8% (95%CI: 25.8%-33.8%) hospitalization rates and 14.6% (95%CI: 11.5%-17.8%) adverse outcome rates. Among patients treated with hydroxychloroquine throughout the course of disease, the prevalence was 0.7% (95%CI: 0.4%-1.0%, Figure 1). Conclusion: Patients with SLE had a higher risk of COVID-19. Hydroxychloro-quine might beneft to reduce the overall hospitalization rate and prevalence rate of COVID-19, and alleviate infammatory damage in the chronic stage of viral infection by inhibiting over activation of the immune system.