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1.
Genomics Proteomics Bioinformatics ; 2020 Jul 30.
Article in English | MEDLINE | ID: covidwho-689153
3.
World J Pediatr ; 16(4): 326-332, 2020 Aug.
Article in English | MEDLINE | ID: covidwho-613534

ABSTRACT

During the COVID-19 epidemic, it is important for ensuring infection prevention and control in the pediatric respiratory clinics. Herein, we introduced the practice of infection prevention and control in pediatric respiratory clinics in China. Triage measures for patients who visit respiratory clinics, quality control for pediatric respiratory clinics and other preventive measures for related examinations and treatment have been introduced in this review article.

4.
Chin. Trad. Herbal Drugs ; 6(51): 1427-1434, 20200328.
Article in Chinese | ELSEVIER | ID: covidwho-380519

ABSTRACT

Recently, the coronavirus disease 2019 (COVID-19) has broken out in China, similar with the sever acute respiratory syndrome (SARS) outbroke in 2003, this pestilence has wide epidemic, strong infectivity and high pathogenicity, which led a great impact on the production, life and people's health in China, and brought huge losses to the economy as well. These two kinds of pestilence were caused by human highly pathogenic coronavirus SARS-CoV-2 and SARS-CoV, respectively. Traditional Chinese medicine, as a unique medical way from China, plays an indelible role in ensuring people’s health. By comparing the epidemiology, clinical manifestations, therapeutic principles and methods of traditional Chinese medicine, this paper puts forward the similarities and differences of traditional Chinese medicine in the prevention, treatment and recovery periods in COVID-19 and SARS, and gives corresponding suggestions.

5.
J Integr Med ; 18(4): 275-283, 2020 07.
Article in English | MEDLINE | ID: covidwho-345240

ABSTRACT

Since the outbreak of novel coronavirus pneumonia (coronavirus disease 2019, COVID-19), it has rapidly spread to 187 countries, causing serious harm to the health of people and a huge social burden. However, currently, drugs specifically approved for clinical use are not available, except for vaccines against COVID-19 that are being evaluated. Traditional Chinese medicine (TCM) is capable of performing syndrome differentiation and treatment according to the clinical manifestations of patients, and has a better ability of epidemic prevention and control. The authors comprehensively analyzed the etiology and pathogenesis of COVID-19 based on the theory of TCM, and discussed its syndrome differentiation, treatment and prevention measures so as to provide strategies and reference for the prevention and treatment with TCM.


Subject(s)
Betacoronavirus , Coronavirus Infections/diagnosis , Coronavirus Infections/therapy , Medicine, Chinese Traditional , Pneumonia, Viral/diagnosis , Pneumonia, Viral/therapy , Coronavirus Infections/etiology , Coronavirus Infections/prevention & control , Humans , Pandemics/prevention & control , Pneumonia, Viral/etiology , Pneumonia, Viral/prevention & control
6.
Ann Transl Med ; 2020.
Article | WHO COVID | ID: covidwho-249209

ABSTRACT

Background: The new coronavirus pneumonia (NCP) is now causing a severe public health emergency The novel coronavirus 2019 (2019-nCoV) infected individuals by binding human angiotensin converting enzyme II (ACE2) receptor ACE2 is widely expressed in multiple organs including respiratory, cardiovascular, digestive and urinary systems in healthy individuals These tissues with high expression level of ACE2 seemed to be more vulnerable to SARS-CoV-2 infection Recently, it has been reported that patients with tumors were likely to be more susceptible to SARS-CoV-2 infection and indicated poor prognosis Methods: The tissue atlas database and the blood atlas were used to analyze the distribution of ACE2 in human tissues or organs of cancers and normal samples Starbase dataset was applied to predict the prognosis of cancers according to expression level of ACE2 Results: In this study, we demonstrated a landscape profiling analysis on expression level of ACE2 in pan-cancers and showed the risky of different type of cancers to SARS-CoV-2 according to the expression level of ACE2 In addition, we found that ACE2 was both differential expression and related to the prognosis only in liver hepatocellular carcinoma (LIHC) Relative high expression of ACE2 indicated a favorable prognosis in LIHC, but they might be more susceptible to SARS-CoV-2 Conclusions: We indeed emphasized that LIHC patients with high expression level of ACE2 should be more cautious of the virus infection Our study might provide a potential clue for preventing infection of SARS-CoV-2 in cancers

7.
Singapore Med J ; 2020 Apr 29.
Article in English | MEDLINE | ID: covidwho-145282

ABSTRACT

In this paper, we aim to provide professional guidance to clinicians who are managing patients with chronic liver disease during the current coronavirus disease 2019 (COVID-19) pandemic in Singapore. We reviewed and summarised the available relevant published data on liver disease in COVID-19 and the advisory statements that were issued by major professional bodies, such as the American Association for the Study of Liver Diseases and European Association for the Study of the Liver, contextualising the recommendations to our local situation.

10.
Int J Environ Res Public Health ; 17(7)2020 03 27.
Article in English | MEDLINE | ID: covidwho-17675

ABSTRACT

In a large-scale epidemic outbreak, there can be many high-risk individuals to be transferred for medical isolation in epidemic areas. Typically, the individuals are scattered across different locations, and available quarantine vehicles are limited. Therefore, it is challenging to efficiently schedule the vehicles to transfer the individuals to isolated regions to control the spread of the epidemic. In this paper, we formulate such a quarantine vehicle scheduling problem for high-risk individual transfer, which is more difficult than most well-known vehicle routing problems. To efficiently solve this problem, we propose a hybrid algorithm based on the water wave optimization (WWO) metaheuristic and neighborhood search. The metaheuristic uses a small population to rapidly explore the solution space, and the neighborhood search uses a gradual strategy to improve the solution accuracy. Computational results demonstrate that the proposed algorithm significantly outperforms several existing algorithms and obtains high-quality solutions on real-world problem instances for high-risk individual transfer in Hangzhou, China, during the peak period of the novel coronavirus pneumonia (COVID-19).


Subject(s)
Coronavirus Infections/epidemiology , Coronavirus , Motor Vehicles , Pneumonia, Viral/epidemiology , Quarantine , Transportation of Patients/organization & administration , Algorithms , Appointments and Schedules , Betacoronavirus , China/epidemiology , Coronavirus Infections/therapy , Disease Outbreaks , Epidemics , Heuristics , Humans , Pandemics
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