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International Journal of Health Sciences ; 6:1403-1414, 2022.
Article in English | Scopus | ID: covidwho-1995094


The purpose of this study is to analyze the influence of Transformational Leadership and Organizational Citizenship Behavior on Organizational Resilience during the COVID-19 pandemic at Hospital in East Kalimantan, Indonesia. A cross-sectional study was conducted in December 2021 at a type B referral hospital for COVID-19 in East Kalimantan. Questionnaires was used to obtain data, and the data was analyzed using SmartPLS software. The population of the study was the manager of the type B referral hospital for COVID-19 in East Kalimantan. A total of the respondents were 218 managers. The sampling technique in this research was total sampling with a response rate of 97%. The results of this study show: Transformational Leadership has a significant positive effect on the Organizational Resilience (p = 0,036), and Organizational Citizenship Behavior has no significant effect on the Organizational Resilience (p = 0,295). Leadership competence should be one of the hospital director's main capacities to enhance hospital resilience during a crisis. © 2022 International Journal of Health Sciences.All rights reserved.

Acta Medica Indonesiana ; 53(4):497-504, 2021.
Article in English | MEDLINE | ID: covidwho-1624256


BACKGROUND: Convalescent plasma is a potentially beneficial, tolerable, and available additional treatment option for COVID-19. This study aims to evaluate whether the administration of convalescent plasma therapy leads to improved clinical outcomes in COVID-19 patients compared to standard medical therapy. METHODS: We conducted a search of Pubmed, Cochrane, and EBSCO for studies assessing the clinical question using inclusion and exclusion criteria. Selected studies were critically appraised, and the results were summarized. RESULTS: A meta-analysis of 10 randomized clinical trials (RCTs), an RCT, a case-control clinical study were selected and assessed. Only the case-control clinical study showed that convalescent plasma administration improved the clinical outcomes of patients with COVID-19, including all-cause mortality, hospital length of stay, and the need for mechanical ventilation. On the contrary, the other two studies of a higher level of evidence showed no significant clinical outcome improvement with convalescent plasma therapy. CONCLUSION: The effectiveness of convalescent plasma therapy in improving clinical outcomes of patients with COVID-19 was still inconclusive due to several study limitations and other possible causes.

Acta Medica Indonesiana ; 53(4):407-415, 2021.
Article in English | MEDLINE | ID: covidwho-1624206


BACKGROUND: Many studies identified the risk factors and prognostic factors related to in-hospital COVID-19 mortality using sophisticated laboratory tests. Cost and the availability of supporting blood tests may be problematic in resource-limited settings. This multicenter cohort study was conducted to assess the factors associated with mortality of COVID-19 patients aged 18 years and older, based on history taking, physical examination, and simple blood tests to be used in resource-limited settings. METHODS: The study was conducted between July 2020 and January 2021 in five COVID-19 referral hospitals in Indonesia. Among 1048 confirmed cases of COVID-19, 160 (15%) died during hospitalization. RESULTS: Multivariate analysis showed eight predictors of in-hospital mortality, namely increased age, chronic kidney disease, chronic obstructive pulmonary disease, fatigue, dyspnea, altered mental status, neutrophil-lymphocyte ratio (NLR) >= 5.8, and severe-critical condition. This scoring system had an Area-under-the-curve (AUC) of 84.7%. With cut-off score of 6, the sensitivity was 76.3% and the specificity was 78.2%. CONCLUSION: The result of this practical prognostic scoring system may be a guide to decision making of physicians and help in the education of family members related to the possible outcome.