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Journal of Pharmaceutical Research International ; 33(55A):34-38, 2021.
Article in English | Web of Science | ID: covidwho-1579784


Introduction: A bidirectional relationship exist between the COVID-19 diagnosed & recovered patient and Type 2 Diabetes Mellitus. As per the various article available in public domain it has been proved that entry of COVID - 19 virus can lead to a series of pathological changes into a patient's body which may lead to the development of insulin resistance and damage to the pancreas. The patient in our case was a COVID - 19 survivor which was diagnosed with type 2 DM during the treatment. The patient was started with the Glargine insulin when she was undergoing her treatment in the hospital for COVID - 19 Symptoms. Her fasting and postprandial blood sugar level was controlled with the insulin. After her discharged she was started with the Metformin 500 mg twice a day but her blood sugar was not controlled with the Metformin monotherapy, so we started with the triple drug combination Metformin + Glimepiride + Pioglitazone. After 1 month of follow-up, it was seen that the blood sugar level was not controlled, so the Pioglitazone was replaced with the DPP-4 inhibitor drug Vildagliptin and again the patient was asked to come for follow-up after 15 days, it was seen in this follow-up that the patients' blood sugar was dramatically controlled. Conclusion: COVID - 19 triggered Type 2 DM is the result of cytokine storm develop during the disease. Metformin and DPP - 4 inhibitors reduce the insulin resistance in type 2 diabetes patients and helps to achieve the euglycemic goal of the patient.

European Journal of Molecular and Clinical Medicine ; 8(1):229-234, 2021.
Article in English | EMBASE | ID: covidwho-1107114


Boosting immunity is the new requirement of today's world. So, the factors responsible for immunity are getting the importance. Ojas is one of the key factors responsible for immunity. Ojas connects the mind to the body and consciousness. It nourishes all body tissues and influences the physical, psychological and emotional life of a person directly. So, an attempt is made to study Ojas and OjovahaSrotas in details including its formation, primary seat, types, perception of Ojas according to various acharyas, symptoms of its elevation as well as depletion and how to assess it practically in the patient, ways to increase the Ojasetc. This can help to have a deep insight of the subject and can help in the early detection of the Ojodushtilakshanas. Also, diseases including Ojodushti are given collectively in order to elaborate the practical view of the subject. The further scope of the study includes the pre-clinical and clinical trials of the Ojovrudhhikar drug (drugs increasing Ojas).