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1.
Journal of Mazandaran University of Medical Sciences ; 32(210):88-99, 2022.
Article in Persian | GIM | ID: covidwho-1999188

ABSTRACT

Background and purpose: Coronavirus disease (COVID-19) causes different symptoms. Mizaj or temperament in Persian traditional medicine is a specific feature of every human being. The aim of this study was to determine the relationship between Mizaj and severity of symptoms in patients with COVID-19. Materials and methods: A descriptive correlational study was performed in patients with symptomatic COVID-19 during recovery and interviews were carried out to record patients' symptoms (fever, cough, chills, etc.). Salmannezhad Mizaj questionnaire was used to determine the patients' temperament (warm, cold, wet, and dry). The number of symptoms in each patient was determined and the severity of symptoms was classified into three levels: mild, moderate, and severe. The relationship between Mizaj and COVID-19 clinical symptoms were assessed by Chi-square and Pearson correlation coefficients.

2.
Journal of Management, Spirituality & Religion ; 18(5):444-461, 2021.
Article in English | APA PsycInfo | ID: covidwho-1893764

ABSTRACT

This research aims mainly to emphasize the contribution of indigenous tacit Knowledge of traditional medicine to treat COVID-19 symptoms in a traditional and Islamic context in Algeria. In order to do so, we proceed as follows. First of all, to find out whether traditional treatment delays the death of people affected by COVID-19, a survival analysis was carried out among a sample of 74 hospitalized patients at the University Hospital Center in a region located to the west of Algeria. Subsequently, interviews with 185 traditional healers from the same region were held to identify the plants on which these patients relied. Three main results emerge from our study: first, the use of traditional treatment helped prolong the survival of people with COVID-19. Second, we were able to identify 11 medicinal plants. Third, Healers over 80 who had acquired tacit knowledge knew more medicinal plants compared to other age groups. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

3.
Journal of Management, Spirituality & Religion ; 18(5):462-481, 2021.
Article in English | APA PsycInfo | ID: covidwho-1893761

ABSTRACT

Indigenous knowledge and practices suffer marginalisation when it comes to seeking solutions to social problems. The world misses out on the richness of this knowledge and practices and role that they can play. This qualitative existential phenomenological study explored experiences of African indigenous knowledge holders and practitioners on their views regarding solutions towards COVID-19 pandemic. Interviews were conducted through WhatsApp and face-to-face with ten participants and data were analysed thematically. The findings show African knowledge and practices that could combat COVID-19 in terms of restrictions, heat related remedies and plant related remedies, and how these knowledge and practices can be applied through ancestral, environmental, metaphysical and generational modes. Africa and the world could benefit from how indigenous people respond to diseases such as COVID-19 and adopt/adapt some of these knowledge and practices;indigenous knowledge and practices have a role to play by contributing solutions to the world's problems. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

4.
Philippine Journal of Science ; 150(5):925-937, 2021.
Article in English | CAB Abstracts | ID: covidwho-1871666

ABSTRACT

Herbal plants are often used as alternative medicine because they contain active compounds for the treatment of diseases and disorders with minimal side effects, and are easily obtained from the surrounding environment. Some of them have antiviral activity. This study aimed to analyze the potential of phytochemical compounds in the leaf of "pangi" (Pangium edule Reinw) as anti-SARS-CoV-2 using molecular docking study. The drug- and lead-likeness properties of the selected compounds were obtained from the Swiss ADME and admetSAR online server tools. Molecular dynamics (MD) simulation of the selected ligand was carried out to validate the stability of the interaction. The results suggested that pangi leaves contain three compounds with remarkable binding affinities with Mpro (main protease) and RBD (receptor binding domain) were (5.beta.)pregnane-3,20.beta.-diol, 14.alpha.,18.alpha.-[4-methyl-3-oxo-(1-oxa-4-azabutane-1,4-diyl)]-, diacetate (PD), ethyl cholate (EC), and bis(3,5,5-trimethylhexyl) phthalate. Because EC will be metabolized in the body into cholic acid (Cho), this compound was then docked and validated using MD simulation. The compound has the best free binding energy (G) with SARS-CoV-2 (-7.1 kcal/mol with Mpro and -6.0 kcal/mol with RBD). Moreover, the compound is bound strongly to the active cavity of Mpro on Thr24, Thr26, His41, and Cys145 residues. The MM-GBSA calculation showed that the interaction of Cho with Mpro was higher than with RBD. According to the RMSD (root mean square deviation), RMSF (root mean square fluctuation), the radius of gyration (Rg), and intermolecular hydrogen bond (H-bond) analysis obtained from 50 ns MD simulations, Cho formed stable interactions with Mpro and RBD. The finding of this study indicated that Cho showed good anti-SARS-CoV-2 activity. The potential of the compound to inhibit the virus can serve as a starting point in the process of developing COVID-19 therapeutic natural medicine.

5.
Phyton ; 91(6):1129-1140, 2022.
Article in English | CAB Abstracts | ID: covidwho-1865753

ABSTRACT

For thousands of years, plant based herbal medicines have been utilized by millions of people all over the world. Plant materials or products are used in different folk/traditional medical systems, such as the Chinese, African and Indian medical systems, like Siddha, Ayurveda, Unani, and Homeopathy. Tinospora cordifolia (TC) is a medicinal plant belonging to the family Menispermaceae. It is a big deciduous, climbing shrub growing prevalently in the tropical part of Indian subcontinent regions such as India, Pakistan, Nepal, Bhutan, Bangladesh and Srilanka, and in Myanmar, and China. Guduchi, Giloy, Shindilkodi, and Amritha are all the common names for this plant. Extracts from different parts of this herbal plant have been used to treat many diseases. In Ayurvedic medicine, extract from this plant is used for preparing "rasayanas", which is known to cure diabetes, skin diseases, allergic conditions, jaundice, cardiovascular diseases, rheumatoid arthritis, poisoning, and microbial infections. T. cordifolia has a many bioactive phytochemicals that have been isolated from its aerial parts and roots. Many bioactive principles have been reported from this plant which belong to various classes like alkaloids, aliphatic compounds, diterpenoid lactones, phenolics, flavonoids, glycosides, sesquiterpenoids, lignans, steroids and polysaccharides. T. cordifolia possesses medicinal properties such as antioxidant, antiallergic, antiinflammatory, antimicrobial, antiviral, antidote, antitumor, antileprotic, antispasmodic, and antidiabetic properties. The present review will provide a comprehensive therapeutic potential of T. cordifolia.

6.
Journal of Drug Delivery and Therapeutics ; 11(6-s):188-194, 2021.
Article in English | CAB Abstracts | ID: covidwho-1836313

ABSTRACT

Background: Unani System of Medicine (USM) is one of the traditional systems of medicine practiced in India and the Indian subcontinent. It is a holistic system of health care based on inceptive principles applied by Hippocrates, Galen, and Ibn-e-Sina, the founders of present-day medicine. USM encompasses a distinct way of looking at the human body and it considers health to be the result of natural dynamic harmonious balance within the body. USM also recognizes the presence of inherent wisdom which is responsible for controlling all physiological functions, maintenance of health, restoration of health, and self-healing. This intrinsic ability of the body to restore health and the mechanism that activates the body's healing process is called Tabi'at/ physis. The ultimate goal of prevention of disease can be obtained by optimization of tabi'at/physis, increasing the host defense. It can be achieved through the implication of asbab-e-sitta zarooriyah which includes some Unani Regimenal Therapies also, fostering change in lifestyle habits resulting in good health. Aims: In this raging pandemic all the therapeutic strategies are based on destroying the agent, breaking the means of transmission and immunization. Although we are leaving behind a huge gap in maintaining the host defense even though it has a crucial role in disease dynamics. In this paper, we have attempted to highlight the concept of tabi'at/Physis and its optimization to prevent this disease and its transmission.

7.
Natural Volatiles & Essential Oils ; 8(5):4210-4216, 2021.
Article in English | CAB Abstracts | ID: covidwho-1812953

ABSTRACT

The global current scenario shows that COVID-19 has spread worldwide and drugs prescribed to treat the disease are under study. The imperative requirement of drugs to treat COVID-19 has made significant changes in the pharmacological industry. Discovering drugs for such a pandemic has been a crucial target, with standardisation, preclinical and clinical studies being conducted in all possible age groups. Siddha medicines have found their way in the treatment of COVID-19 largely and increasingly been accepted worldwide. Among such constant trials, implementation of the molecular docking process has helped to reveal the importance of different Siddha medicines in the first place as therapeutics to COVID-19. The Government bodies have also recommended these antiviral compounds to treat symptoms such as cold, fever, breathing difficulty and sore throat. This study aims to focus on to gather awareness on the impact of various Siddha medicines and their insights into molecular level to fight against Coronaviruses. As a result of this review, it was found that the phytochemical compounds present in various siddha medicines such as Kabasura Kudineer, Adathodai Kudineer, Maramanjal Kudineer and so on, have been docked with the possible target proteins of SARS-CoV-2 virus to disclose that they have potential action on the virus and declare to act as the candidate drugs in COVID-19 treatment.

8.
Natural Volatiles & Essential Oils ; 8(5):1121-1127, 2021.
Article in English | CAB Abstracts | ID: covidwho-1812883

ABSTRACT

Background: COVID-19 is classified as a janapadodhwamsa vikara in Ayurveda (epidemic disease). In Chapter 3 of Charaka Samhita: Vimana Sthana, the concept of an epidemic is discussed. "... even though there is dissimilarity in the physical constitution of human beings, still there are such factors which are common to all individuals and vitiation of these factors leads to the simultaneous manifestation of diseases having the same set of symptoms leading to the destruction of countries. Factors which are common for all the inhabitants of a country are air, water, location and seasons." 3/6] Vimana Sthana Janapadodhwamsa is a condition in which the environment - air, water, land, and seasons - has been tainted, resulting in the simultaneous occurrence of a sickness among huge populations (epidemic) and the destruction of human habitations. The three medications used to treat COVID-19 are all traditional medications. According to the texts, each of them acts in the following ways: Sudarsana Churna: Treats all three doshas and all forms of fevers, including Agantuja jwara, Sannipata jwara, and others., Talisadi Churna: heals Jwara, svasa, kasa, aruchi (loss of taste);Vaataanulomana (aiding the normal flow of vayu), Dhanvantara Gutika: remedies Svasa, Kasa;Vaataanulomana (aiding the normal flow of vayu), Dhanvantara Gutika: cures Svasa, Kasa;Vaataanulomana (stimulates digestion). Aim & Objectives - Study the awareness about use of Ayurved medications as an adjuvant therapy in COVID-19 pandemic in urban population. Material & Methods: Subjects will be collected from common population who have been tested positive for COVID-19. Observations & result - The assessment will be done by validated Post-test questionnaire & Interpret.

9.
Natural Volatiles & Essential Oils ; 8(5):6648-6660, 2021.
Article in English | GIM | ID: covidwho-1812786

ABSTRACT

Background: COVID-19 is an infectious disease that is caused by a newly discovered coronavirus. The infection prevention and the Control measures are associated with the Supportive Care. Various home remedies and herbal treatments for COVID-19 have been advocated in India. These remedies for covid-19, traditional practices with home made herbal extracts and other valuable herbs has helped people protect themselves from these communicable diseases including covid-19 by boosting of immune system.

10.
Natural Volatiles & Essential Oils ; 8(5):302-308, 2021.
Article in English | CAB Abstracts | ID: covidwho-1812601

ABSTRACT

Siddha System of Medicine practiced in South part of Indian constituency. It is one of the ancient Traditional systems of India, mostly followed by Tamil peoples. Adhi Sivan and 18 Siddhar's are the founders of Siddha system of medicine. Traditional systems are highly focused worldwide after covid 19 pandemic situations. In Tamil Nadu which is southern state of India Siddha system of medicine highly prescribed during Chikungunya and Dengue spread. More peoples are benefited through the system. In India, Ministry of AYUSH, focusing on traditional Indian system of medicines for the treatment of Covid 19. Siddha Medicine is one among the AYUSH system. In this situation author wish to explore the details of Siddha medicine in the way of what is Siddha? Who are Qualified Siddha Doctor and Pattern of Study etc.... This review is helpful to the scientific world to know, who is Registered Siddha Medical practitioner and many details about Siddha System of Medicine.

11.
Natural Volatiles & Essential Oils ; 8(4):11269-11296, 2021.
Article in English | CAB Abstracts | ID: covidwho-1790523

ABSTRACT

Aim: To evaluate the knowledge, awareness and perception levels of the general public on the immune boosting effects of Ayurveda against Covid 19. Background: Ayurveda is a traditional medicine that is usually followed in India. Ayurveda has the power and strength to build up an immunity system to fight against the Covid 19. Materials and methods: A cross sectional study was conducted among the general public visiting a private dental institution. Random sampling was employed. Closed ended, a structured questionnaire was prepared and circulated through google forms. The data collected was tabulated and analyzed by SPSS software (version 23).

12.
Natural Volatiles & Essential Oils ; 8(4):8558-8585, 2021.
Article in English | CAB Abstracts | ID: covidwho-1790286

ABSTRACT

BACKGROUND: The COVID-19 pandemic has become a major cause of concern for the healthcare profession. Indian medicine practitioners, such as in, allopathic systems are used for treating the infection, but unfortunately there is no specific medicine for COVID-19. The Ayurvedic fraternity is looking forward to the active involvement in the prevention and cure for COVID-19. AIM: The aim of this study was to assess the awareness about COVID-19 symptoms and precautions among practitioners of traditional Indian medicine like Ayurveda, Siddha and Homeopathy. MATERIALS AND METHODS: A survey was conducted among 112 individuals practising Indian Medicine through google form. The responses were recorded in the SPSS software version 25. The responses were recorded in the form of bar graphs and pie charts. RESULT: Among the 112 individuals 99.9% respondents exhibited high level knowledge about COVID-19 symptoms and precautions. Most of the respondents chose home remedies and natural ayurvedic medicines and syrup for boosting their immunity and to keep themselves healthy and fit. CONCLUSION: The individuals who attended this survey were well aware of COVID-19 and its precautions and thus were confident in treating the various symptoms.

13.
Journal of Drug Delivery and Therapeutics ; 11(4-s):119-126, 2021.
Article in English | CAB Abstracts | ID: covidwho-1744443

ABSTRACT

Neem (Azadirachta indica) a member of Meliaceae plays an immense role in human health and disease which is attributed to its composition of Bioactive Secondary Metabolites (BASM). It has been widely used in Indian Traditional Systems of Medicine that includes Ayurveda, Siddha, Unani, Homeopathy and other Folklore Systems of Medicine practiced in the Indian Subcontinent for the treatment and prevention of various diseases. Current global health perspectives and medical practice in the post COVID era has no other way but to seek to merge alternative systems of medicine with evidence-based therapeutic aspects for a better understanding of the metabolic process and its effects in the human body. The studies based on animal model established that neem and its chief constituents play pivotal role in anticancer management through the modulation of various molecular pathways including p53, pTEN, NF-B, PI3K/Akt, Bcl-2, and VEGF. Besides, NEEM plays a vital role in the management of diabetics and its associated long term complication through ROS scavenging and ameliorative potentials to restore oxidative injury/inhibit enzymes linked to. Overall NEEM is considered as GRAS medicinal plant that modulates metabolic inflammations without side effects. Though it has been confirmed that neem and its constituents play role in the scavenging of free radical and prevention of disease pathogenesis, a clear scientific basis of its pharmacoinformatics is still lacking. Gas Chromatography-Mass Spectroscopy (GC-MS) analysis of the fractions revealed the presence of 62 metabolites.

14.
Journal of Applied Biosciences ; 168:17456-17467, 2021.
Article in French | CAB Abstracts | ID: covidwho-1727466

ABSTRACT

Objective: This study was conducted to identify medicinal plants in the fight against Coronavirus disease, influenza and colds cited by travelers who came for their Covid test at the Institut Pasteur of C..te d'Ivoire. Methodology and Results: A semi-structured interview was conducted with 527 travelers from April 1 to June 30, 2021. The interviewed travelers were predominantly male (69.4%). Travelers going to France (28.46%) were the most numerous. The most represented age groups were 41-64 (43.83%) and 25-40 (43.26%). When the level of education is considered, the surveyed travelers have a higher level of education (89.94%). Entrepreneurs (13.85%), traders (12.66%), company directors (12.33%), students (8.54%) and health workers (6.45%) are the majority. Only 21.63% of travelers used traditional medicine in the last 12 months prior to the survey. Various plants are used to fight (33.43%) or prevent (56.57%) Coronavirus disease (7.02%), influenza (3.60%) and colds (2.84%). In total, 13 species of medicinal plants divided into 13 genera and 13 families were cited. Azadirachta indica (Meliaceae) with citation frequencies (cf) of 22%, Zingiber officinale (Zingiberaceae) with cf of 21% and Citrus limon (Rutaceae) with cf of 14% were the most cited species. Conclusion and application of results: These plants could be used for research and development of phytomedicines against Coronavirus, influenza and cold.

15.
Journal of Biology and Today's World ; 10(6), 2021.
Article in English | CAB Abstracts | ID: covidwho-1716790

ABSTRACT

Background: Up to the 21st century, Traditional, Complementary and Alternative Medicine (TCAM) is still used despite the wide spread of orthodox medicine. The magnitude, predictors and types of herbal remedies used for COVID-19 are assessed to tailor evidence based policy and drug formulation against COVID-19.

16.
Journal of Drug Delivery and Therapeutics ; 11(3-s):142-144, 2021.
Article in English | CAB Abstracts | ID: covidwho-1603524

ABSTRACT

Unani System of Medicine is also known as Greco-Arabic medicine, and developed into an elaborate scientific medical system by Arab and Persian physicians, such as Rhazes (850-925AD), Avicenna (980-1037AD), Al-Zahrawi and Ibn Nafis. It is practiced in India since eighth century AD and is a recognized Indian traditional system of medicine with good infrastructure for education;research and manufacturing unitswhich are well regulated by the Government. In Unani medicine there are well developed pharmacopeia and pharmaceutical processings for single & compound formulations for the treatment of several local and systemic ailments. The most important formulation among various Unani formulations is Sharbat-e-Unnab, a Unani pharmaceutical preparation acting as Dafa-e-Sual (antitussive), Khashunat-e-Halaq (sore throat), Musaffi-e-Khoon (blood purifier), Musakkin-e-Hiddat-e-Khoon (suppressive blood heat) etc. Unnab (Ziziphus jujuba Mill./Jujube) fruit is the main ingredient of the formulation. Unnab is also an ingredient of Unani Joshanda which has been recommended for relief in upper respiratory tract symptoms in mild cases of COVID-19. Few scientific studies related to Sharbat Unnab have been conducted in problems like Acne vulgaris and Primary Hypertension. Apart from this Unnab, the main ingredient has also been studied for its antioxidant and anti-cancerous activities. This formulation is being used by Unani physicians since time immemorial. Therefore, this paper will describe the brief review of the formulation along with its ingredient.

17.
Current Science ; 120(1):22-24, 2021.
Article in English | GIM | ID: covidwho-1602324

ABSTRACT

This study examined MCTs Specific responses and responses to COVID-19 are available in the public domains (Government website, medical research databases and media) to pull Lessons for India. As part of the outbreak response, it is a must that AYUSH professionals clinical and public health needs Orientation and training around translation conditions. Indeed, the set of AYUSH, they have trained more than 3000 healthcare professionals to monitor and respond to COVID-19. Get the clue of PRC Framework and Early Engagement from TCM is a model for the AYUSH system. AYUSH should aim to empower them professionals by incorporating integrative medicine, public health and professional development into their curricula. Apart from the current situation, this is ways to enhance AYUSH's contribution by ensuring that integrated activities, effective research and public advantage in general. Such efforts can bring AYUSH is closer to reality and thus creates opportunity in the age of public health emergency like the current pandemic and thus remain in "peaceful" times.

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