ABSTRACT
COVID-19 has slowed the growth of, the global economy, which has certain practical significance. Consequently, this study seeks to analyze the investment opportunities in the medical sector before and after the COVID-19 outbreak. In this study, the Markowitz mean–variance (MV) model, capital asset pricing model (CAPM), and correlation models are constructed based on the principle of Markowitz MV and correlation analysis. Simultaneously, statistical analysis is used to verify the analysis, and the MATLAB statistical tool is used to build the model. The results show that the actual expected yield of China's medical sector is significantly higher than that calculated by the CAPM before and after the pandemic, and that the investment value of the medical sector is undervalued by the market. From the perspective of risk, China's medical sector has a stable systemic risk premium. Based on the above analysis, when building investment portfolios in the post-pandemic era, investors should appropriately allocate stocks in the medical and pharmaceutical sectors to improve the portfolio income and diversify the investment risk. © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.