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1.
Psychiatric Times ; 39:6-9, 2022.
Article in English | CINAHL | ID: covidwho-2034127

ABSTRACT

The article offers a perspective on the growing interest in the treatment of mood disorders with psychedelic drugs. It describes the mechanism of action of psychedelic drugs. An overview of the results of a randomized clinical trial on the efficacy of psilocybin compared with escitalopram for major depressive disorder is provided. It discusses ethical considerations for the psychedelic-assisted therapy and offers a look into the expansion of psychedelic research into other areas of psychiatry.

2.
American Family Physician ; 106(3):318, 2022.
Article in English | ProQuest Central | ID: covidwho-2033979

ABSTRACT

A collaboration between AFP and the Lown Institute promotes a vision of delivering health care that is based on the evidence, balanced in its approach, and focused on the patient.

3.
Boletin de Malariologia y Salud Ambiental ; 61(3):486-495, 2021.
Article in Spanish | CAB Abstracts | ID: covidwho-2033877

ABSTRACT

Persistent COVID is characterized by functional and psychological symptoms and sequelae that persist for more than 12 weeks post infection, such as: fatigue, dyspnea, anxiety, depression;generating inconveniences in the resumption of work activities of workers. A descriptive, cross-sectional epidemiological study was carried out, evaluating the reincorporation of workers operating in metalworking industries in Lima, Peru;recovered and persistent COVID, between the third quarter 2020 and the first quarter 2021. The Borg dyspnea scales and the modified dyspnea scale of the Medical Research Council (mMRC) were applied, in addition to the Goldberg anxiety and depression scale. The results were analyzed using descriptive statistics, using measures of central tendency and dispersion. It was observed that more than 80% of recovered workers are reinstated;and for persistent COVID, between 75% and 43% are reinstated for charges 8121 and 8122, respectively. Respiratory effort at rest was normal by the Borg scale for each group, while in effort a value R2 = 0.2986 was obtained, indicating no reincorporation in 74.51% and 43.33% in categories 8121 and 8122, respectively;also 45.12% and 42.68% of the recovered workers and persistent COVID showed symptoms of fatigue;36.25% and 35.26% anxiety;25.4% and 15.21% of depression, respectively;Likewise, the total of workers were overweight with an average BMI> 26 Kg/m2;being higher in women (27.4 Kg/m2). COVID-19 affects the health of workers (recovered and persistent COVID), reduces return to work and consequently the productivity of companies.

4.
Boletin de Malariologia y Salud Ambiental ; 61(Edicion Especial II 2021):114-122, 2021.
Article in Spanish | CAB Abstracts | ID: covidwho-2033749

ABSTRACT

Due to the pandemic, an increase in mental health problems has been reported in members of the health personnel, with the self-report being an initial way of evaluating it. The objective was to determine the factors associated with the perception of repercussions in the mental sphere in health professionals in Latin America before COVID-19. An analytical cross-sectional study was carried out between June and August 2020 in Latin America. The perception of repercussions was measured through an instrument previously validated in Peru, which was taken virtually from 406 doctors, nurses and others;this was crossed versus other variables. The main concern was returning home and infecting their family (22% strongly agree), followed by feeling the abuse because they do not give them the necessary amount of personal protective equipment (13% strongly agree) and perceiving mental exhaustion for all the activities they did (12% strongly agree). In the multivariate analysis, the older there was a lower perception of mental repercussion (aPR: 0.98;95% CI: 0.97-0.99;p value = 0.012);In addition, those who had a greater perception of repercussions in the mental sphere also had more anxiety at a low level (aPR: 1.84;95% CI: 1.14-2.98;p value = 0.013) and post-traumatic stress (aPR: 2.28;95% CI: 1.61-3.22;p value <0.001), adjusted for depression and stress. Despite being an exploratory analysis, important associations were found in the mental sphere;which should continue to be investigated in larger studies.

5.
Boletin de Malariologia y Salud Ambiental ; 61(Edicion Especial II 2021):97-105, 2021.
Article in Spanish | GIM | ID: covidwho-2033720

ABSTRACT

COVID-19 has generated an unprecedented pandemic. This scenario could affect the mental health of healthcare personnel, influencing their work performance with the possibility of leaving long-term sequelae. The objective was to determine the socio-occupational factors associated with suffering from anxiety, depression and stress in health professionals in the Peruvian highlands during the pandemic. Cross-sectional study. Doctors and other professionals at the Ramiro Priale Priale National Hospital in the Peruvian highlands were surveyed virtually. Depression, anxiety and stress were measured with the DASS-21 scale;these were associated with different socio-labour variables. More severe depression was found at older ages and if a family member had been ill at home, but less severe depression was found among those who had children, those who had more years of professional practice and those who had social security. Those who had children had less anxiety;less severe anxiety and those who had a relative away from home who became ill;on the other hand, those who worked more hours per day had more moderate anxiety, severe anxiety if the respondent had become ill and both types if a family member had died had more moderate anxiety. Those who worked more hours per day and those who had a deceased family member had more stress. The most relevant characteristics of health workers with mental health problems were older age, family history of COVID-19, history of death of a family member from COVID-19 and longer working hours.

6.
Current Journal of Neurology ; 21(2):83-90, 2022.
Article in English | EMBASE | ID: covidwho-2033507

ABSTRACT

Background: Fatigue is one of the most frequent complaints in patients with motor neuron diseases (MNDs), with a significant impact on the quality of life (QOL). There is lack of enough evidence for current pharmacological or non-pharmacological treatments of fatigue in this population to be applied in clinical setting. Energy conservation strategies are one of the key interventions for fatigue management in chronic diseases. We aimed to investigate the effect of applying these techniques in the fatigue management of patients with MND. Methods: This randomized controlled trial (RCT) study was carried out on 28 patients with MND. Participants were randomly assigned to either the intervention or control group. In addition to routine treatment, patients in the intervention group participated in 3 weekly 1-hour energy conservation programs provided by an experienced occupational therapist. The Fatigue Severity Scale (FSS) score, 36-Item Short Form Survey (SF-36), and Canadian Occupational Performance Measure (COPM) were measured at baseline, immediately after the last intervention session, and one month later. Results: FSS and COPM significantly changed after the course in the intervention group (P < 0.001 and P = 0.001, respectively). Both FSS and COPM improved significantly toward the final assessment only in the intervention group. The SF-36 changes were not significant in each of the groups. Conclusion: According to the findings of the present study, using energy conservation strategies could lead to better mid-term fatigue management and occupational performance improvement, but it did not improve QOL in patients with MND.

7.
Iranian Journal of Pharmaceutical Research ; 21(1), 2022.
Article in English | EMBASE | ID: covidwho-2033387

ABSTRACT

Donepezil hydrochloride is an acetylcholine esterase inhibitor studied and approved to treat Alzheimer’s disease (AD). However, this drug can have positive therapeutic potential in treating different conditions, including various neurodegenerative disorders such as other types of dementia, multiple sclerosis, Parkinson’s disease, psychiatric and mood disorders, and even infectious diseases. Hence, this study reviewed the therapeutic potential of this drug in treating Alzheimer’s and other diseases by reviewing the articles from databases including Web of Science, Scopus, PubMed, Cochrane, and Science Direct. It was shown that donepezil could affect the pathophysiology of these diseases via mechanisms such as increasing the concentration of acetylcholine, modulating local and systemic inflammatory processes, affecting acetylcholine receptors like nicotinic and muscarinic receptors, and activating various cellular signaling via receptors like sigma-1 receptors. Despite many therapeutic potentials, this drug has not yet been approved for treating non-Alzheimer’s diseases, and more comprehensive studies are needed.

8.
Asian Journal of Social Health and Behavior ; 5(2):75-84, 2022.
Article in English | Web of Science | ID: covidwho-2033319

ABSTRACT

Introduction: The purpose of this research was to predict mental illness among university students using various machine learning (ML) algorithms. Methods: A structured questionnaire-based online survey was conducted on 2121 university students (private and public) living in Bangladesh. After obtaining informed consent, the participants completed a web-based survey examining sociodemographic variables and behavioral tests (including the Patient Health Questionnaire (PHQ-9) scale and the Generalized Anxiety Disorder Assessment-7 scale). This study applied six well-known ML algorithms, namely logistic regression, random forest (RF), support vector machine (SVM), linear discriminate analysis, K-nearest neighbors, Naive Bayes, and which were used to predict mental illness among university students from Dhaka city in Bangladesh. Results: Of the 2121 eligible respondents, 45% were male and 55% were female, and approximately 76.9% were 21-25 years old. The prevalence of severe depression and severe anxiety was higher for women than for men. Based on various performance parameters, the results of the accuracy assessment showed that RF outperformed other models for the prediction of depression (89% accuracy), while SVM provided the best result than other models for the prediction of anxiety (91.49% accuracy). Conclusion: Based on these findings, we recommend that the RF algorithm and the SVM algorithm were more moderate than any other ML algorithm used in this study to predict the mental health status of university students in Bangladesh (depression and anxiety, respectively). Finally, this study proposes to apply RF and SVM classification when the prediction of mental illness status is the core interest.

9.
Aims Public Health ; 9(4):630-643, 2022.
Article in English | Web of Science | ID: covidwho-2033208

ABSTRACT

We sought to explore mental health and psychosocial impact among young people (18 to 24 years old) in Bogota during the first months of the COVID-19 pandemic. Methods: We carried a cross sectional study using a web-based survey to assess mental health and personal impact among 18 to 24 years old living in Bogota during the first 4 months of the 2020 COVID-19 pandemic lockdown. The depressive symptoms were measured with PHQ-8 and anxiety symptoms with (GAD-7). We also designed a questionnaire exploring changes in personal, family and social life. Results: Overall, 23% of the sample (n = 834) reported mild depressive symptoms (males 24% and females 23%);29% reported moderate depressive symptoms (males 28%, females 30%);22% moderate-severe symptoms (males 20%, females 23%) and 17% severe symptoms (males 15%, females 17%). Mild anxiety symptoms were reported by 29% of the sample (males 30%, females 29%);moderate anxiety symptoms by 29% (males 26%, females 30%);moderate-severe 18% (males 15%, females 20%) and severe anxiety by 6.0% (males 6.0% and females 6.0%). High symptoms of depression (PHQ-8 >= 10) were associated with being female, considering that the quarantine was stressful, having one member of the family losing their job, worsening of family relationships, decrease of physical activity and having a less nutritious diet. Having high anxiety symptoms (GAD-7 >= 10) were associated with sometimes not having enough money to buy food. Conclusions: The first months of the pandemic lockdown were associated with high depressive and anxiety symptoms among young persons living in Bogota, Colombia. Increasing public health measures to provide support for young people is needed during lockdowns and it is necessary to further explore the long-term mental health impact due to personal, family and social changes brought by the COVID-19 pandemic.

10.
Open Access Macedonian Journal of Medical Sciences ; 10(T7):170-175, 2022.
Article in English | EMBASE | ID: covidwho-2033206

ABSTRACT

BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19) has increased the burden of psychological stress. AIM: This study aims to determine the relationship between the length of isolation, the results of the COVID-19 polymerase chain reaction swab test, the time of reporting, and the level of knowledge with the degree of depression and anxiety in patients with swab results confirmed by SARS-CoV-2. METHODS: This study is an analytical observational study with a cross-sectional design. After the data were collected, a bivariate statistical analysis was carried out for the Kruskal–Wallis and Spearman Test. RESULTS: A total of 25 patients with a diagnosis of COVID-19 were included in this study. CONCLUSION: The study found that the length of isolation, frequency of swab, the time spent focusing on COVID-19, and level of knowledge were not related to the degree of depression and anxiety. However, mental attention and appropriate intervention are an important part of clinical care for those at risk.

11.
Open Access Macedonian Journal of Medical Sciences ; 10(T7):159-163, 2022.
Article in English | EMBASE | ID: covidwho-2033205

ABSTRACT

BACKGROUND: Colorectal cancer has been known as the leading cause of death with depression as the most common coexisting morbidity. Factors related to depression among cancer patients are required to be explored. AIM: This study aims to investigate factors related to depression among colorectal cancer patients in Medan. METHODS: This cross-sectional predictive analytical multivariate study was conducted through March–May 2021 in Haji Adam Malik General Hospital, Medan, involving 105 colorectal patients visiting digestive surgery outpatient clinic who fulfilled inclusion and exclusion criteria. Subjects were requested to fill in personal data on participant’s form. Direct interview was conducted in accordance with COVID-19 health protocols. To assess depression score, Hospital Anxiety and Depression Scale-Depression subscale questionnaire was used in the study. RESULTS: Our study found among independent variables that we assessed, five variables;length of education, number of comorbidities, gender, occupation, and marital status are independent risk factors related to the occurrence of depression among colorectal cancer patients (adjusted R2 = 68.5%). CONCLUSION: By acknowledging risk factors related to depression among these patients, early intervention and tailored education for both patients and their loved ones can be done.

12.
Frontiers in Psychiatry ; 13, 2022.
Article in English | Web of Science | ID: covidwho-2032821

ABSTRACT

BackgroundThe sporadic coronavirus disease (COVID-19) epidemic has placed enormous psychological stress on people, especially clinicians. The objective of this study was to examine depression, anxiety, quality of life (QOL), and related social psychological factors among young front-line clinicians in high-risk areas during the COVID-19 sporadic epidemic in China and to provide a reference for formulating reasonable countermeasures. MethodsIn this cross-sectional study, demographic information, COVID-19-related questions, anxiety (Generalized Anxiety Disorder-7, GAD-7), depression (Patient Health Questionnaire-9, PHQ-9), insomnia (Insomnia Severity Index, ISI), stress (Perceived Stress Scale-10, PSS-10), and QOL (World Health Organization Quality of Life-brief version, WHOQOL-BREF) were collected. Binary logistic regression analysis was used to test the relationships between anxiety and/or depression and other related problems. Multiple linear regression analysis was used to test the relationships among factors influencing QOL. ResultsA total of 146 young front-line clinicians were included. The prevalence rates of depression, anxiety, and anxiety-depression comorbidity were 37.7% (95% CI = 29.7-45.6%), 26.0% (95% CI = 18.8-33.2%), and 24.0% (95% CI = 17.0-31.0%), respectively. Severe stress (OR = 1.258, 95% CI = 1.098-1.442, P < 0.01) and insomnia (OR = 1.282, 95% CI = 1.135-1.447, P < 0.01) were positively correlated with depression. Severe stress (OR = 1.487, 95% CI = 1.213-1.823, P < 0.01) and insomnia (OR = 1.131, 95% CI = 1.003-1.274, P < 0.05) were positively correlated with anxiety. Severe stress (OR = 1.532, 95% CI = 1.228-1.912, P < 0.01) was positively correlated with anxiety-depression comorbidity. However, insomnia (OR = 1.081, 95% CI = 0.963-1.214, P > 0.05) was not correlated with anxiety-depression comorbidity. The belief that the vaccine will stop the COVID-19 pandemic (OR = 0.099, 95% CI = 0.014-0.715, P < 0.05) was negatively correlated with anxiety and anxiety-depression comorbidity (OR = 0.101, 95% CI = 0.014-0.744, P < 0.05). Severe stress (B = -0.068, 95% CI = -0.129 to -0.007, P < 0.05) and insomnia (B = -0.127, 95% CI = -0.188 to -0.067, P < 0.01) were negatively correlated with QOL. The belief that the vaccine could provide protection (B = 1.442, 95% CI = 0.253-2.631, P < 0.05) was positively correlated with QOL. ConclusionsThe prevalence of depression, anxiety, and even anxiety-depression comorbidity was high among young front-line clinicians in high-risk areas during the COVID-19 sporadic epidemic in China. Various biological and psychological factors as well as COVID-19-related factors were associated with mental health issues and QOL. Psychological intervention should evaluate these related factors and formulate measures for these high-risk groups.

13.
Revista Latino-Americana De Enfermagem ; 30, 2022.
Article in English | Web of Science | ID: covidwho-2032684

ABSTRACT

Objective: to analyze the Mental Health Literacy of young and aged men living in Brazil in the COVID-19 pandemic context. Method: a qualitative study conducted with 87 men by means of an asynchronous online survey. The data were processed in the NVIVO12 (R) software, structured with the Collective Subject Discourse method and analyzed through Anthony Jorm's theoretical concept of Mental Health Literacy. Results: six central ideas emerged from the analysis of a synthesis discourse on the components of the Mental Health Literacy, namely: Ability to recognize specific disorders or different types of psychological distress;Knowledge and beliefs about risk factors and causes;Knowledge and beliefs about self-help interventions;Knowledge and beliefs about available professional help;Attitudes that facilitate recognition and the search for adequate help;and Knowledge on how to seek information on mental health. Conclusion: there are differences in the mental health literacy of young and aged men living in Brazil during the COVID-19 pandemic. Aged men were more competent for mental health care management and protection than young men, in relation to the Mental Health Literacy levels.

14.
Asia-Pacific Journal of Clinical Oncology ; 18:60, 2022.
Article in English | EMBASE | ID: covidwho-2032339

ABSTRACT

Objectives: In order to provide useful reference information for researchers in the field of pharmacology and toxicology, this paper studies the current research hot spots in this field, as well as the correlation closeness between research topics. Methods: This paper studies on the hot papers of pharmacology and toxicology field based on ESI (Essential Scientific Indicators) database, and the time span of the data is from January 1, 2010 to December 31, 2020. The data about these 110 hot papers are analyzed by the authors from the aspects of published time, country/territory, institution, journal, citation, and so on. The methods of multi-dimension analysis, cluster analysis, Vosviewer visualization are used to analyze these papers. Results: The results shows that United States is in the first place in the ranking of published papers, England is in the second place, and China is in the third place. The research hotspots are COVID-19, anxiety, depression, and mental health. Conclusions: The cluster of hot papers show the correlativity of the topic in the pharmacology and toxicology field. This research provides researchers in the field of pharmacology and toxicology with the current international hot research direction, and helps China researchers to improve their research in the field.

15.
Psychiatria Danubina ; 33:42-43, 2021.
Article in English | EMBASE | ID: covidwho-1647467

ABSTRACT

Recent researches, following the pandemic, have shown in people, especially the youngest ones, an increase of suffering, articulated in tiredness and being worried, all feelings linked primarily to the national closure of schools and social meeting... Depressive and languishing mood seem to the "normal" condition of everyday feeling of each of us, young and adult.

16.
HemaSphere ; 6:3064-3065, 2022.
Article in English | EMBASE | ID: covidwho-2032171

ABSTRACT

Background: Non-Hodgkin lymphoma (NHL) is the largest group of hematological malignancies and represented 12% of all new cancer cases in metropolitan France in 2018. The survival outcomes of NHL patients have improved due to important therapeutic advances. Age-standardized 5-year net survival from 2010 to 2015 in France was 86% for follicular lymphoma (FL) and 61% for diffuse large B cell lymphoma (DLBCL), which are above the average survival rates in Europe (FL 72% and DLBCL 51%). In this context, the question of quality of life in NHL patients is garnering increasing interest. To the best of our knowledge, few data from France have addressed the issue of living conditions of long-term NHL survivors at the scale of the general population. Aims: To identify the clinical and social determinants of long-term health related quality of life (HRQoL) in NHL survivors in the general population and to describe their socio-professional reintegration, socio-economic status, sexual wellbeing and the impact of COVID. Methods: All patients were registered in the population-based cancer registry specialized in hematological malignancies in the Côte d'Or area (A French Department with a total of 532,901 residents in 2019). We identified patients diagnosed with DLBCL or FL according to the third edition of the International Classification of Diseases for Oncology (ICD-O- 3), from January 1st 2010 to December, 31st 2017, and who were still alive on March, 1st 2021, with an updated address. Patients under 18 years old and adults unable to provide consent were not eligible. In March 2021, patients completed standardized self-report questionnaires for HRQoL (SF-12), anxiety and depression (HADS), social support (SSQ6), socio-economic deprivation (EPICES). Reminders were sent to non-responders after one month. The determinants of HRQoL were identified using a generalized linear model. Results: Among 436 patients diagnosed, 248 were alive at the study endpoint, of whom 157 (FL 51% and DLBCL 49%) completed the questionnaires, yielding a response rate of 63.3%, the median of time since diagnosis was 76 months [39-133]. The mean age of participants was 67.3 years (SD = 12.4), 55% were men, 74% Ann Arbor stage III-IV, 78% were treated by chemotherapy and immunotherapy, with 99% in the DLBCL group, 11% relapsed after treatment, 64% had no comorbidities and 62% did not have socio-economic deprivation, 27% were employed at the time of the survey, 60% of survivors had not received information about sexuality, 29% reported a negative impact of the disease on their professional activities, 54% reported an impact of the COVID crisis on their life. This impact was socio-economic for 77% and psychological for 23% of respondents. The main factors associated with a negative impact on HRQoL were depression, anxiety, and loss of sexual desire. Summary/Conclusion: Six years after diagnosis, clinical parameters did not have a major influence on HRQoL, except for relapse. The main determinants of HRQoL identified were psychological and social factors. All these elements are potential targets for specific interventions by the social system to improve HRQoL in NHL patients.

17.
HemaSphere ; 6:3024, 2022.
Article in English | EMBASE | ID: covidwho-2032141

ABSTRACT

Background: Informal family caregivers play a pivotal role in supporting patients with hematologic malignancies during their treatment. Due to the toxicities of treatment patients often have serious treatment-related side-effects, and with more treatment being placed in the outpatient settings, family caregivers are often the primary source of support between Hospital visits assisting the patient and managing symptoms. The early phase of treatment has been found particularly stressful, and evidence shows that family caregivers are at higher risk of psychological distress and have unmet support needs impacting their ability to support the patient. Thus, finding new ways to support family caregivers is important within a health care context. Peer to peer support has shown great promise in hematologic patients, and there is a need to investigate psychosocial interventions such as peer to peer support in family caregivers. Aims: To investigate the feasibility of a one-on-one peer support intervention in family caregivers of newly diagnosed hematologic patients. Methods: A one-arm feasibility study was conducted. The intervention consisted of 12-weeks of one-on-one support provided by volunteer family caregivers of a hematologic cancer survivor (named caregiver ambassadors) (n = 17) to a family caregiver of a newly diagnosed patient (n =26). Support was delivered based on the needs and preferences of the family caregiver via telephone, text message, e-mail or face-to-face. The intervention also included a preparatory course for the caregiver ambassadors and available support during the intervention. Primary outcomes were feasibility parameters and secondary outcomes were collected at three time points and included anxiety, depression, sleep disturbances, self-efficacy, and quality of life. Results: The peer support intervention was feasible and safe, and participants reported very high satisfaction with the support (75%). Dropout rate was low (7%) and no adverse events were reported. Over time, family caregivers improved their psychosocial well-being, and caregiver ambassadors overall maintained their levels from baseline. Participants were satisfied with the preparatory course enhancing their role preparation as peer supporters and 14 caregiver ambassadors attended the available support network meetings (n = 6). During the intervention, the total number of contacts between participants were 389 with each dyad having an average of 15 contacts during the 12- weeks. Support was most frequently delivered by telephone and text-messages. In-person meetings were less used due to geographical distances, personal preferences including the patients' illness situation, and covid-19. Summary/Conclusion: We tested the feasibility of a new peer to peer intervention in family caregivers of newly diagnosed hematologic patients. The results demonstrated that the intervention was feasible, safe, and satisfactory in both the caregiver ambassador and family caregiver groups. Flexibility in the delivery and frequency of support was essential and accommodated the individual support needs and preferences. Providing preparation and support for caregiver ambassadors was important. This family caregiver peer to peer intervention has the potential to be a new model of support incorporated in the clinical setting.

18.
HemaSphere ; 6:4034-4035, 2022.
Article in English | EMBASE | ID: covidwho-2032106

ABSTRACT

Background: ERN-EuroBloodNet was established in 2017 as the European Reference Network on Rare Hematological Disorders (RHDs) bringing together nationally recognized centres of excellence with the goal of promoting EU best health care in RHDs. ERN-EuroBloodNet has been recently enlarged integrating 103 HCP from 24 EU-MS. Aims: ERN-EuroBloodNet was conceived to contribute to innovative, efficient and sustainable health systems and facilitate access to better and safer healthcare for EU citizens while decreasing the cross-border health barriers. Methods: Since 2017, ERN-EuroBloodNet established the state-of-the art of RHD allowing the implementation of transversal and disease-specific strategies, where actions on very rare RHD were prioritized. Results: Profile. 182 expert profiles were created freely accessible. Expert centers follow 65,000 RHD patients and treat 5,000 new patients per year, while 24 patients requested support for cross-border health assistance. Expertise. The need to improve access to next-generation sequencing for non-oncological RHD and bone marrow transplantation for sickle cell disease (SCD) was identified. Also, significant disparities in the clinical practice of primary vitreoretinal lymphoma were found and we demonstrated that less than 30% of children with SCD benefit from adequate annual stroke risk monitoring. Guidelines. A repository of 68 Clinical Practice Guidelines (CPG) classified on quality of evidence and consensus approach was created. Recommendations for diagnosis and treatment of methemoglobinemia was published in collaboration with EHA. A CPG on Adult Burkitt Lymphoma is under development. Next topics focus long-term complications in hemoglobinopathies and patients' pathways&summary. Education. ERN-EuroBloodNet Webinars were launched for professionals with 26 Thursdays Webinars and 3 EBAH accredited Topic on Focus on Cutaneous Lymphoma, Thrombotic Microangiopathies, and Bone Marrow Failures. A collaboration was established for EHA & ERN-EuroBloodNet Spotlight on Castleman Disease. For patients, 3 Topic on Focus were launched for Myelodysplastic syndromes, SCD, and Cutaneous lymphoma. Past webinars are available at EuroBloodNet EDU Youtube channel. Preceptorships on SCD will be launched soon. Telemedicine. 43 complex cases have been inter-professionally discussed in the Clinical Patient Management System with 21 outcome reports delivered. Registries. 184 Registries were identified through the European Rare Blood Diseases Platform (ENROL), endorsed by the EHA. The ENROL project, which includes rare anemias, dendritic cell leukemia and von Villebrand's disease pilots, aims to collect exhaustive and therefore epidemiological data for RHDs. The final objective is a possibility of EU health planningl and the promotion of research by identifying cohorts of patients. ERNEuroBloodNet launched the collaborative platform on patients with red blood cells and COVID-19 containing so far 373 patients. Collaborations. collaborative research projects were encouraged like EC-funded projects i.e., genomics and personalized medicine in hematological diseases (GenoMed4All) and the properties and viability of erythrocytes (EVIDENCE), or the International Hemoglobinopathy Research Network (INHERENT) for genomic and phenotypic correlations. Summary/Conclusion: The implementation of well-defined strategies but above all adapted to the specific and not yet covered needs of RHD has led to the realization of concrete projects. This has laid the foundations to strengthen health systems in the field of RHD and allow them to flourish under the new EU4Health programme.

19.
Paediatrics & Child Health ; 27:S130-S135, 2022.
Article in French | Web of Science | ID: covidwho-2032084

ABSTRACT

Objectives: Reports of mental health difficulties in Canadian children increased during the COVID-19 pandemic, and new research suggests that children who exhibit marked symptoms of inattention and hyperactivity were disproportionately affected. As a result, the pandemic also had a deleterious effect on families. This study aimed to: 1) examine whether children's symptoms of inattention and hyperactivity at the beginning of the 2020-2021 school year were associated with mindful parenting (or mindfulness parenting) at the end of the school year;and 2) examine whether children's symptoms of depression and anxiety at the end of the year tempered this association. Methods: Parents of 114 young children in a large Canadian city participated in this study during the winter of 2020 and spring of 2021. Parents completed several rating scales to measure children's mental health symptomatology and attention to parenting practices. Results: Inattention and hyperactivity symptoms in children were significantly negatively associated with attentive parenting during the school year, and depressive symptoms in children tempered this relationship. In particular, when children's depressive symptoms were mild or moderate, higher levels of inattention and hyperactivity were associated with lower levels of attentive parenting. On the other hand, when depressive symptoms were severe in children, inattention and hyperactivity symptoms were not predictive of attentive parenting. Conclusions: Children's mental health, namely symptoms of inattention/hyperactivity and depression, is related to difficulties in attentive parenting during the COVID-19 pandemic. These results may indicate to physicians which families need more support during the pandemic.

20.
The British Journal of Social Work ; 2022.
Article in English | Web of Science | ID: covidwho-2032019

ABSTRACT

In this article, the authors provide empirical data about the Spanish population during lockdown on the following topics: center dot The impact of the coronavirus disease (COVID-19) crisis is not limited to health and disease-related aspects exclusively. center dot The pandemic has affected everybody. However, consequences in terms of psychological distress have been different depending on gender and age. center dot The results of this study point towards the importance of considering psychosocial factors in the development of social work interventions that enable citizens to mitigate the impact of social and health-related emergency situations and improve their coping capacities, improving resilience. center dot Social work professionals have been involved in social care since the beginning of the pandemic, but their practice has continued after lockdown ended, with all the consequences that this entails. center dot Social work has become visible as an essential profession during the pandemic and must be present, not only in the provision of services but also in the formulation of social policies. center dot The current situation presents a professional challenge to develop comprehensive interventions in order to deal with future social and health emergencies. The coronavirus disease (COVID-19) crisis has had an unprecedented impact on Spanish society regarding health and social issues. The purpose of this study is to analyse the potential relationship that may exist between social and personal factors and the levels of psychological distress experienced by the Spanish population during lockdown. A quantitative cross-sectional study was conducted using an ad hoc online questionnaire consisting of forty-three questions. The survey was administered to a sample of 3,436 people that were living in Spain during the second extension of the State of Alarm. A linear mixed model with random intersection has been used. Our findings demonstrate the intersectional vulnerability of young women and the impact different factors such as a COVID-19 diagnosis, experiencing symptoms compatible with COVID, an existing disability, a previous illness or solitary confinement may have on psychological distress levels. Conversely, higher resilience levels have shown a correlation with lower psychological distress levels.

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