Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 99
Filter
1.
J Clin Med ; 11(20)2022 Oct 17.
Article in English | MEDLINE | ID: covidwho-2071549

ABSTRACT

BACKGROUND: Evidence has shown a close association between COVID-19 infection and renal complications in both individuals with previously normal renal function and those with chronic kidney disease (CKD). METHODS: The aim of this study is to evaluate the in-hospital mortality of SARS-CoV-2 patients according to their clinical history of CKD or estimated glomerular filtration rate (eGFR). This is a prospective multicenter observational cohort study which involved adult patients (≥18 years old) who tested positive with SARS-CoV-2 infection and completed their hospitalization in the period between November 2020 and June 2021. RESULTS: 1246 patients were included in the study, with a mean age of 64 years (SD 14.6) and a median duration of hospitalization of 15 days (IQR 9-22 days). Cox's multivariable regression model revealed that mortality risk was strongly associated with the stage of renal impairment and the Kaplan-Meier survival analysis showed a progressive and statistically significant difference (p < 0.0001) in mortality according to the stage of CKD. CONCLUSION: This study further validates the association between CKD stage at admission and mortality in patients hospitalized for COVID-19. The risk stratification based on eGFR allows clinicians to identify the subjects with the highest risk of intra-hospital mortality despite the duration of hospitalization.

2.
IOP Conference Series. Earth and Environmental Science ; 1083(1):012027, 2022.
Article in English | ProQuest Central | ID: covidwho-2062802

ABSTRACT

Covid-19 virus began in December 2019, and the coronavirus (COVID-19) has impacted several countries, affecting more than 90,000 patients and making it a global pandemic. Where health workers include doctors, nurses, and other health workers, play a role in treating infected patients and become the vanguard in the handling of coronavirus. Based on data Indonesia positive cases of Covid-19 as many as 3,872,738 people and patients recovered 3,381,884 people and patients who died as many as 118,883 people and 48.3% of the cases of COVID-19 patients in Indonesia are elderly. The actual SARS-CoV-2 outbreak caused a highly transmissible disease with a tremendous impact on elderly people. This study focused on very elderly patients (over 80 years old) was created with the aim of analyzing the relationship of some diseases in the elderly that affect covid-19 at Royal Prima Hospital Medan in 2020, And the conclusion of this study based statistically shows that there is no link between DM, heart and kidney diseases in the elderly that affect covid-19, as well as the presence of hypertensive disease and ARI in the elderly that affects covid-19.

3.
Journal of Clinical and Basic Research ; 6(1):11-27, 2022.
Article in English | CAB Abstracts | ID: covidwho-2057219

ABSTRACT

Coronavirus disease 2019 (COVID-19) is a severe acute respiratory disease with a high prevalence. According to the research and statistical data, in January 2021, there have been 92,262,621 confirmed cases of COVID-19 and more than two million deaths. Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the main cause of this disease. In addition to the respiratory system, the disease affects the gastrointestinal tract, central-peripheral nervous system, circulatory system, and kidneys. Therefore, any therapeutic action to reduce COVID-19-related symptoms and complications is essential. In this study, we conducted a systematic review of the published literature and preprints on the efficacy of erythropoietin (EPO) and recombinant human EPO as a safe stimulant and tissue protector in the treatment of COVID-19. We also briefly described the structure of coronavirus, its pathogenesis, and the structure of EPO and recombinant human EPO. All relevant articles published in the Science Direct, PubMed, and Google Scholar databases were searched. According to the results, EPO is a cytoprotective cytokine induced by hypoxia. The pleiotropic effects of EPO are associated with its erythrocyte-forming, anti-apoptotic, anti-inflammatory activities. It also exerts protective effects on the heart, lungs, kidneys, arteries, and central and peripheral nervous systems. It has been demonstrated that EPO can increase hemoglobin levels, thereby increasing oxygen delivery to the tissues. Therefore, recombinant human EPO therapy can be used for counteracting the adverse effects of COVID-19 including hypoxic myocarditis, acute renal failure, pulmonary edema, and brain-spinal cord ischemic injury. Overall, the use of EPO and recombinant human EPO therapy increases blood coagulation, tumor growth, thromboembolism, and purification of red blood cells, which must be accompanied by anticoagulants such as heparin.

4.
Clinical Nephrology ; 96(4):207-215, 2021.
Article in English | GIM | ID: covidwho-2056047

ABSTRACT

Background: Continuous renal replacement therapy (CRRT) has become an important multiple organ support therapy and it is widely used in the intensive care unit (ICU). The aim of this study was to clarify the association between CRT and 28-day mortality in critically ill coronavirus disease 2019 (COVID-19) patients receiving mechanical ventilation. Materials and methods: 112 respiratory decompensated critically ill adult patients with COVID-19 admitted to a COVID-19-designated ICU were included in this retrospective cohort study. Data on demographic information, comorbidities, laboratory findings upon ICU admission, and clinical outcomes were collected. The Kaplan-Meier method and Cox proportional hazard model were applied to determine the potential risk factors associated with 28-day mortality.

5.
Clinical Nephrology ; 95(5):227-239, 2021.
Article in English | GIM | ID: covidwho-2056046

ABSTRACT

The presentation of kidney damage in Coronavirus disease 2019 (COVlD-19) varies significantly. According to recent studies. the development of acute kidney injury (AKI) in severe cases of COVID-l9 infection significantly worsens the prognosis of these patients. The pathological changes in kidneys might be caused directly by the cytopathic effect mediated by local replication of the severe acute respiratory syndrome coronavirus-Z (SARS-CoV-Z) or indirectly because of systemic immune response or by- percoagulation, so-called immunothrombosis. Other causes. such as hypovolemia and hypoxia. may also contribute to AKI. Acute kidney disease often develops in elderly patients with underlying comorbidities or in critically ill patients with severe respiratory failure. It is known that AKJ is a risk factor for mortality in C OVID-l9 patients.

6.
Psychonephrology: A guide to principles and practice ; : 415-429, 2022.
Article in English | APA PsycInfo | ID: covidwho-2047984

ABSTRACT

Continuing professional development has changed drastically in the era after the COVID-19 pandemic. In-person conferences are now a distant memory, but staying current and relevant (especially in interdisciplinary fields such as psychonephrology) continue to be very important. This chapter seeks to provide readers with an overview of how a community such as psychonephrology clinicians can harness the power of social media to expand learning opportunities. Exploring issues pertinent to both psychiatrists and nephrologists, this chapter highlights the potential for social media platforms to help grow a conjoint digital community of practice that explores the intersection of psychiatry/psychology in patients with kidney disease. The chapter begins with an overview of why social media has become a key modality in modern continuing professional development, highlighting both education theory and also practical examples that have emerged from related disciplines within medicine. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

7.
Drug Safety ; 45(10):1121, 2022.
Article in English | ProQuest Central | ID: covidwho-2045055

ABSTRACT

Introduction: Hypertension is a serious disease that occurs when blood pressure is persistently elevated over time1. During the COVID19 vaccination campaign, several reports of hypertension occurred in plausible temporal relationship with immunization have been reported. Objective: To explore a possible signal of risk of hypertension associated with COVID-19 immunization using VigiBase® the World Health Organization (WHO) pharmacovigilance database and to review the evidence available from real world. Methods: We performed a disproportionality analysis using data on spontaneous reports recorded in VigiBase®. Data have been extract on May 8th, 2022. We calculated reporting odds ratio (ROR) as a measure of disproportionality for hypertension defined by the Standardized Medical Dictionary for Regulatory Activities (MedDRA) query (SMQ) narrow. ROR was estimated for all reports including the MedDRA preferred term (PT) "hypertension", "blood pressure increased" and "hypertensive crisis" (cases). All other reports have been defined as non-cases. All reports in which the suspected causative agent was a COVID-19 vaccine were used as index reports and all other reports as reference. A signal was defined by at least three reports of the PT of interest and ROR025 > 1. We reviewed the medical literature using MEDLINE from January 2021 to May 2022 using "COVID-19 vaccines" AND "hypertension" as a search terms to check for evidence from observational studies. Results: As of May 8th, 2022, VigiBase® included 3,746,090 reports of adverse events following immunization for COVID-19 vaccines and 87,653 de-duplicated reports of hypertension define by the SMQ. We identified 34,955 reports of "hypertension" (ROR:1.3;ROR025:1.2), 47,733 reports of "blood pressure increased" (ROR:2.6;ROR025:2.6) and 3,741 reports of "hypertensive crisis" (ROR:4.0;ROR025:3.8) in which a COVID-19 vaccine was indicated as suspected causative agent. Most frequently co-reported symptoms (> 9%) included headache (n = 16.817;19.2%), dizziness (n = 12,892;14.7%), fatigue (n = 8,406;9.6%). Overall, 75% of cases (n = 65,761) have been classified as not serious. A meta-analysis of observational studies that includes 357,387 individuals reported 13,444 events of blood pressure abnormal or increased2. These events have been often described as short periods of hypertensive response and often observed in patients with risk factors. Conclusion: Our results confirmed a signal of risk of events of elevated blood pressure following immunization with COVID-19 vaccines. However, there is no evidence that these episodes could result in serious complication typically associated with hypertension, such as stroke, aneurysms, heart failure, myocardial infarction and chronic kidney disease.

8.
BMC Nephrol ; 23(1): 304, 2022 09 05.
Article in English | MEDLINE | ID: covidwho-2038672

ABSTRACT

BACKGROUND: There is a growing literature on guidelines regarding Ramadan fasting for chronic kidney disease (CKD) patients. However, most studies only consider the impact of fasting on renal function. This study additionally aims to assess factors influencing Ramadan fasting in patients with CKD. METHOD: This is a prospective before and after cohort study. CKD patients were counseled regarding fasting and followed-up post-Ramadan for renal function status, actual fasting behavior, and other relevant outcomes. RESULTS: Of the 360 patients who attended the pre-Ramadan consultation, 306 were reachable after Ramadan of whom 55.3% were female. Of these 306 67.1% reported that they had fasted, 4.9% had attempted to fast but stopped, and 28% did not fast at all. Of these 74 has a post-fasting kidney test. Of the patients, 68.1% had stage 3A CKD, 21.7% had stage 3B, 7.9% stage 4, and only 2% stage 5. Of those who fasted, 11.1% had a drop in Glomerular Filtration Rate (eGFR) of 20% or more. Those who did not fast (16.7%) presented a similar drop. Conversely, among the few who attempted to fast and had to stop, half showed a drop in eGFR of more than 20%. In linear regression, fasting was not associated with post-Ramadan eGFR, when controlling for age and baseline eGRF. There were 17 (5.6%) significant events, including one death. More significant events occurred among the group who fasted some of Ramadan days, 26.7% of the subjects experienced an adverse event-while 4.7% of the group who did not fast had a significant adverse event compared to 4.4% among those who fasted all Ramadan. CONCLUSION: Fasting was not a significant determining factor in renal function deterioration in the study's population, nor did it have any significant association with adverse events.


Subject(s)
Diabetes Mellitus, Type 2 , Renal Insufficiency, Chronic , Cohort Studies , Diabetes Mellitus, Type 2/complications , Female , Glomerular Filtration Rate , Humans , Islam , Male , Prospective Studies
9.
Psychol Health Med ; : 1-8, 2022 Sep 20.
Article in English | MEDLINE | ID: covidwho-2037220

ABSTRACT

The COVID-19 pandemic process may affect the physical and psychosocial health in patients with chronic kidney disease (CKD). The aim of this study was to compare the quality of life, physical activity, fear of COVID-19 and mental health in CKD patients and healthy individualsand compare the aforementioned parameters in end-stage renal disease (ESRD) and renal transplantation (RTx) patients during the pandemic. Eighty-two patients (33 ESRD, 49 RTx) and age-gender matched 108 healthy individuals were included. Quality of life (Short Form 36 Health Survey Questionnaire-SF-36), physical activity (short form of the International Physical Activity Questionnaire -IPAQ-SF), fear of COVID-19 (Fear of COVID-19 Scale-FCV-19S) and mental health (Hospital Anxiety and Depression Scale-HADS) were evaluated. Physical activity levels and all SF-36 scores except mental health in CKD patients were significantly lower than healthy individuals (p < 0.05). FCV-19S and HADS scores were similar between the groups (p > 0.05). ESRD patients' pain and general health perceptions scores of SF-36 were lower than RTx patients' (p < 0.05). Quality of life and physical activity levels were worse in CKD patients compared to healthy individuals during the pandemic. The participants had fear of COVID-19, poor mental health and low physical activity. For these reasons, psychosocial and physical activity interventions for the both groups may be beneficial for the affected outcomes during COVID-19 pandemic.

10.
Annals of Emergency Medicine ; 78(4 Suppl):S16-S16, 2021.
Article in English | GIM | ID: covidwho-2035698

ABSTRACT

Study Objective: There have been concerns that some patients with sepsis-life-threatening organ dysfunction caused by a dysregulated host response to infection-may be overlooked with a quick Sequential Organ Failure Assessment (qSOFA)2 in the emergency department (ED). Despite this, little is known about the risk factors associated with sepsis among patients with qSOFA<2 in the ED.

11.
Iranian Journal of Kidney Diseases ; 16(4):259-265, 2022.
Article in English | GIM | ID: covidwho-2026841

ABSTRACT

Introduction. SARS-CoV-2 infection have been reported to have a greater mortality rate in adults receiving dialysis, as compared to general population. Hence, vaccination is very important in this vulnerable population group, in order to achieve an acceptable level of immunity. The aim of this study was to compare the level of anti-SARS-CoV-2 anti-spike protein receptor-binding domain IgG neutralizing antibody before and after vaccination with two doses of SinopharmR vaccine, in patients undergoing hemodialysis. Methods. Ninety patients on maintenance in-center hemodialysis received two doses of SinopharmR COVID-19 vaccine with an interval of about 28 days. Anti-SARS-CoV-2 anti-spike protein receptor-binding domain IgG (Anti-RBD) neutralizing antibody was measured with an ELISA kit. All statistical analyses were performed by SPSS-26 software. Results. The absolute mean (+or- SE) change in antibody titer following full-scheduled vaccination was 8.98 +or- 1.49 micro g/mL. The rate of seroconversion was 31.1% after two doses of vaccine. In addition, the rate of seroconversion was higher in those with a history of COVID-19 than in those without a history of COVID-19. Conclusion. Conclusion. The administration of booster doses, doubling of the dose in each episode of vaccination schedule as well as combination of different vaccine platforms are recommended to increase COVID-19 vaccine efficacy in hemodialysis patients.

12.
Osmaniye Korkut Ata Universitesi Fen Bilimleri Enstitusu Dergisi / Osmaniye Korkut Ata University Journal of Natural and Applied Sciences ; 5(2):1041-1052, 2022.
Article in English | GIM | ID: covidwho-2026789

ABSTRACT

Covid-19 SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) is a new type of coronavirus known as an infectious upper respiratory tract infection disease. The coronavirus, which poses a great threat to human health worldwide, emerged in Wuhan, China in December 2019. The most important reason for coronavirus epidemics to become a pandemic that the disease was easily transmitted by droplets in close proximity with infected people. The disease spread rapidly all over the world within a few months and it was declared a worldwide epidemic by the World Health Organization in March 2020. It poses a risk for severe diseases such as hypertension, diabetes, cardiovascular disease, cancer, chronic lung disease and chronic kidney disease in the advanced age group. Considering the mortality rates to date, great efforts have been made both worldwide and in our country to manufacture successful drugs and vaccines against Covid-19 infection. The main purpose of this review is to assist in an immune response and preventive work for Covid-19, thanks to the available information about the coronavirus epidemic that deeply affects humanity and the diseases it causes.

13.
Nephrology Nursing Journal ; 49(4):351-358, 2022.
Article in English | ProQuest Central | ID: covidwho-2026722

ABSTRACT

This project examined the effect of an educational intervention on blood pressure control among minority patients with chronic kidney disease (CKD). Adherence to a lowsodium diet is crucial for blood pressure control. It is also vital to assess food insecurity to improve diet adherence, especially among high-risk underrepresented populations. Participants were recruited from a public hospital renal clinic. Knowledge and food access was assessed using CKD and food insecurity questionnaires. Food frequency and 24-hour 3-day food diaries were completed and analyzed. Eighteen patients were enrolled (Black, nonHispanic = 66.6%, Hispanic = 27.7%, uninsured = 33.3%, and Medicaid recipients = 27.7%). Eighty-nine percent of participants screened positive for food insecurity and received vouchers for healthy food from a food depository. Paired t tests showed statistically significant increase in knowledge (p < 0.00) and self-efficacy, and systolic blood pressure improved post-intervention. This study suggests that Black non-Hispanic and Hispanic patients with CKD have limited access to healthy food and consume higher sodium. Patient education, screening for food insecurity, and access to a food depository enhanced adherence to low sodium diet and improved blood pressure control.

14.
Journal of Composites Science ; 6(8):226, 2022.
Article in English | ProQuest Central | ID: covidwho-2023807

ABSTRACT

Hemodialysis (HD) is a life-sustaining treatment of crucial importance in managing end-stage renal disease (ESRD). However, this membrane-based therapy is associated with acute side-effects due to bioincompatibility issues and limitations on the removal of uremic toxins. The present study assessed the influence of hydrodynamic conditions applied during HD treatment on protein-mediated inflammatory and thrombotic responses. The membrane modules considered are commonly used in Canadian hospitals and are comprised of a polymer blend of polyarylether sulfone-polyvinylpyrrolidone (PAES). The membranes morphology and hydrophilicity were assessed using SEM, AFM, BET, and zeta potential. An in vitro study evaluated the adsorptive behavior of fibrinogen (FB) to the membrane under different flow conditions. Lower rates of 200 mL/min promoted slower and significant FB adsorption, leading to more severe inflammatory and thrombotic responses. Hydrodynamic conditions also affected the concentration of all inflammatory biomarkers. Lower flow rates triggered more complement activation as well as coagulation, clotting, and inflammatory responses compared to higher flow rates. At the end of the dialysis session, patients treated with a Qb of 200 mL/min presented a significant increase in the concentration of C5a (232%), properdin (114%), serpin (545%), IL-1α (50%), IL-6 (450%), and vWF (212%). IL-1β and TNF-α concentrations declined by 12.5 and 35.5%, respectively. Male patients experienced more severe inflammatory responses than female patients at the operating conditions considered. Comparing the pre- and post-dialysis levels of female and male patients, female patients experienced significantly higher levels of IL-6 and properdin, while male patients presented higher levels of C5a, IL-1α, and IL-6. The results of this study will help clinical doctors evaluate the impact of HD operating conditions on blood activations before prescribing treatment and inform expectations for outcomes in female and male patients.

15.
Chinese Journal of Nosocomiology ; 32(10):1468-1472, 2022.
Article in English, Chinese | CAB Abstracts | ID: covidwho-2011846

ABSTRACT

OBJECTIVE: To systematically describe the outcomes of patients with COVID-19-associated pulmonary aspergillosis (CAPA). METHODS: All of the researches covering the clinical outcomes of CAPA were retrieved from databases such as ScienceDirect, PubMed, CNKI and MEDLINE (OVID) from Dec 31, 2019 to Dec 1, 2021. The literatures were screened out based on inclusion and exclusion criteria by 2 writers, the data were extracted, the quality of the literatures was evaluated, and meta-analysis was performed. RESULTS: Totally 14 cohort studies were included in this study, with 2 056 severe COVID-19 patients involved, including 338 CAPA patients and 1 718 non-CAPA patients. The incidence rate of CAPA was 16.4% among the ICU patients. As compared with the non-CAPA patients, the mortality rate of the CAPA patients was increased by 21% [risk difference (RD)]=0.21, 95% CI:0.15-0.27, (I-2=0%). No heterogeneity or publication bias was detected (t=1.98, P=0.069). Among the patients with underlying diseases, the patients with chronic obstructive pulmonary disease (COPD) were 2.37 times the risk of CAPA as high as the patients of the non-CAPA group (95% CI: 1.15-4.88, P=0.020). The creatinine level of the CAPA patients was higher than that of the non-CAPA patients (33.32 micro mol/L, 95% CI: 6.81-59.83, P=0.014). As compared with the non-CAPA patients, the patients who received renal replacement therapy were 2.33 times the risk of CAPA (95% CI: 1.43-3.80, P=0.001). CONCLUSION: 16.4% of the severe COVID-19 patients have CAPA, the mortality rate is high. COPD, serum creatinine and renal replacement therapy may remarkably increase the risk of CAPA, and it is suggested that a prospective screening of CAPA should be carried out for the severe COVID-19 patients.

16.
SciDev.net ; 2022.
Article in English | ProQuest Central | ID: covidwho-1999074

ABSTRACT

The war in Ukraine only served to worsen the situation as Russia is Sri Lanka’s third biggest export market for tea and, together with Ukraine, are major sources of tourist arrivals. <span data-mce-type="bookmark" style="display: inline-block;width: 0px;overflow: hidden;line-height: 0;" class="mce_SELRES_start"></span> In April, the Rajapaksa government announced that it would default on payment to creditors totalling a staggering US$51 billion and begin a loan restructuring process. Vithanage, who is doing research on chronic kidney disease that affects farmers in remote rural areas, says it has become prohibitively expensive to do basic work, such as collecting water samples and talking to patients. “Initially, we cooked at our boarding house, but now we are forced to buy food from outside due to shortage of gas, but buying food outside is costly as prices doubled over a year,” says Madushika Sewwandi, a chemical technology graduate student from Matara, a town in southern Sri Lanka.

17.
JK Science ; 24(3):188-192, 2022.
Article in English | ProQuest Central | ID: covidwho-1998879

ABSTRACT

[4] Further, due to a tremendous overload of COVID-19 patients in the hospitals, the regular blood sugar testing had taken a back seat at one point of time. [...]it has been seen that many of these patients were irrationally using or self medicating with high doses of corticosteroids, which added further to the impending doom. [5] As few patients who developed diabetes during their COVID-19 illness were previously unaware of their blood sugar levels, this may have resulted from the direct damage to pancreatic beta cells by the SARS-CoV-2 due to its affinity for the ACE2 receptor and indirectly by damaging smaller blood vessels supplying the beta cells. [6] The major predisposing factors for mucormycosis include uncontrolled diabetes mellitus resulting in diabetic ketoacidosis, other forms of metabolic acidosis, treatment with high dose corticosteroids, chronic, kidney disease, organ or bone marrow transplantation, febrile neutropenia, trauma and severe burns, various malignant hematologic disorders, and deferoxamine therapy in patients undergoing hemodialysis. In cases of angioinvasion, fungal hyphae were clearly seen in the walls of blood vessels or were identified forming thrombi at foci of necrosis.The fungal hyphae were identified in the blood vessel wall or were seen forming thrombi at foci with necrosis of adjacent tissue.

18.
CienciaUAT ; 17(1):6-16, 2022.
Article in Spanish | ProQuest Central | ID: covidwho-1975751

ABSTRACT

Coronavirus 19 (COVID-19) is a prevalent and globally disseminated viral disease that has become a pandemic associated with a high case fatality rate. To date, there are no published studies that describe the influence of the variables associated with the disease, specifically in the border state of Tamaulipas, Mexico. The objective of the present study was to assess the characteristics, complications, fatality rates and risk factors associated to mortality in patients positive to COVID-19 in Tamaulipas, one year after the local emergency. Descriptive frequency of characteristics, complications for prevalence and case fatality rates were used. A multivariate logistic regression model was adjusted to estimate the meaningful risk factors, and Kaplan-Meier survival curves were used to describe the most important comorbidities. The analysis indicated higher infection rates in patients of productive age, with a significant death probability in male patients from the age of 40. The risks associated with hospitalization, such as endotracheal intubation and the presence of pneumonia are important risk factors. Comorbidities with high prevalence;diabetes, hypertension, obesity, and chronic kidney disease (CKD) were significantly associated (P < 0.01) with higher COVID-19 mortality risk in the assessed population. The present study demonstrated some COVID-19 general patterns on frequency and mortality rates. It also suggested particularities in factors associated to mortality in the Tamaulipas population, which require proper attention in vulnerable groups, especially in future outbreaks of the disease.Alternate : Coronavirus 19 (COVID-19), es una enfermedad viral prevalente y diseminada a nivel mundial, considerada una pandemia con alta tasa de mortalidad. A la fecha no existen estudios que describan la influencia de las variables asociadas a la enfermedad en el estado fronterizo de Tamaulipas, México. El objetivo del presente estudio fue evaluar y analizar las características, complicaciones, tasas de letalidad y factores de riesgo asociados a mortalidad en paciente positivos a COVID-19 en el estado de Tamaulipas, a un año de la emergencia local. Se utilizó la frecuencia de casos observados en relación a características, complicaciones y comorbilidades para estimar prevalencias y tasas de letalidad. Se ajustó un modelo de regresión logística multivariada para estimar los factores de riesgo significativos y se utilizaron curvas de supervivencia de Kaplan-Meier para describir las comorbilidades más importantes. Los análisis indicaron una mayor infección en pacientes en edad productiva, con una probabilidad significativa de muerte a partir de los 40 años, más evidente en pacientes masculinos. Los riesgos asociados a la hospitalización, como intubación endotraqueal y neumonía, son factores muy importantes. Las comorbilidades con alta prevalencia (diabetes, hipertensión y obesidad) y enfermedad renal crónica (ERC) están asociados significativamente (P < 0.01) a mayor mortalidad por COVID-19 en pacientes positivos. El presente estudio demostró algunos patrones generales de prevalencia y tasas de letalidad por COVID-19, por lo que se sugieren particularidades en los factores asociados a mortalidad en la población de Tamaulipas que requieren atención en sus grupos vulnerables, sobre todo en posibles casos de rebrotes de la enfermedad.

19.
Canadian Medical Association. Journal ; 194(29), 2022.
Article in English | ProQuest Central | ID: covidwho-1970681
20.
Journal of Ayub Medical College ; 33(Suppl. 1):717-720, 2021.
Article in English | GIM | ID: covidwho-1970294

ABSTRACT

Background: The pandemic of COVID 19 has affected a number of people around the globe. The data from paediatric population is scarce. The present study is aimed to present the paediatric perspective of the disease in terms of different clinical presentations, laboratory parameters, complications, and outcomes so as to develop an insight into disease manifestations in children.

SELECTION OF CITATIONS
SEARCH DETAIL