Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 791
Filter
1.
Annals of Translational Medicine ; : 12, 2022.
Article in English | Web of Science | ID: covidwho-1822668

ABSTRACT

Background: New England Journal of Medicine (NEJM), Lancet, Journal of the American Medical Association (JAMA), and British Medical Journal (BMJ) are collectively known as "the Top Four Medical Journals (TFMJ)" in China. Through the analysis of Chinese scholars' publications in the TFMJ in the recent 10 years, this study aimed to clarify the current situation of high-quality medical research conducted by Chinese scholars and institutions. Methods: Data were retrieved and downloaded manually from PubMed (2011-2020). Information on the publication year, journal, author, affiliation, and citation, etc. were extracted and analyzed using R software. Results: A total of 761 articles were involved in the final analysis. The number of articles published by Chinese scholars in the TFMJ was 135/29,942 (0.45%) in BMJ, 124/14,033 (0.88%) in JAMA, 314/16,117 (1.94%) in Lancet, and 188/15,242 (1.23%) in NEJM (P<0.001). Besides, the letter was the main research type, which was up to 44.54%, and the original research only accounted for 17.47%. The most popular subspecialty and subject were infectious diseases and COVID-19, respectively. The most productive researcher was Chen Wang, and Bin Cao was the most cited Chinese scholar. The most productive institute was Chinese Academy of Medical Sciences and Peking Union Medical College. The most cited study was "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China". Conclusions: The presence of Chinese scholars in the TFMJ has grown, but there is still much room to improve. A Matthew effect in China's high-level scientific research was demonstrated.

2.
CMAJ ; 194(4):E129, 2022.
Article in English | EMBASE | ID: covidwho-1822299
3.
AAPS Journal ; 24(3), 2022.
Article in English | EMBASE | ID: covidwho-1822235
4.
American Journal of Rhinology and Allergy ; 36(3):288-290, 2022.
Article in English | EMBASE | ID: covidwho-1822141
5.
Journal of Acute Care Physical Therapy ; 13(2):61, 2022.
Article in English | EMBASE | ID: covidwho-1821994
6.
Yale Journal of Biology and Medicine ; 94(3):381-382, 2021.
Article in English | EMBASE | ID: covidwho-1820576
7.
E+M Ekonomie a Management ; 25(1):143-160, 2022.
Article in English | ProQuest Central | ID: covidwho-1818793

ABSTRACT

There is no substantial evidence that exists in the literature to establish the link between financial advice and financial capability fully establishes, even though 'getting help'is identified as an important aspect of financial capability. This study sets out to fulfil a couple of objectives. Its primary goal is to investigate the effects that a combination of financial literacy elements (financial attitude, financial knowledge, and financia! behaviour), financial advice as well as financial satisfaction have on individuals' financial capability, and secondly, to test and prescribe the improved scale of financial capability measurement. This research has been administered in Spain at an individual level. Hierarchical regression method along with Z-testwere used. Regressions' outcomes reveal that financial constructs positively impact the individuals' financial capability. From the viewpoint of policymakers, it is vital to fully comprehend the significant factors influencing financial capability to plan better strategies to empower the citizens with adequate skills, abilities, and behaviour so to succeed in dealing with financial matters in daily basis. The originality and value added to the present study is two-fold. Firstly, it comprehensively examines the wide-ranging financial indicators seen as criticai in determining financial capability, which remain yet not quite covered in other studies. Second, both indicators used to measure the financial capability revealed no substantial differences, therefore an improved composite scale is prescribed as useful in measuring financial capability in future research.

8.
Journal of Forensic Medicine and Toxicology ; 38(1):102-106, 2021.
Article in English | EMBASE | ID: covidwho-1818625

ABSTRACT

In view of the ongoing pandemic, healthcare workers are rightfully concerned about performing autopsies, due to the risk of infection. An autopsy surgeon and his/her team can inadvertently be exposed to infectious diseases. Use of appropriate personal protective equipment (PPE) and mortuaries equipped with negative pressure are essential to protect the autopsy team from exposure to potentially infected bodies, bodily fluids, tissues, and aerosolized particles. Unfortunately, in a developing country like India, due to a lack of funding most mortuaries have only the bare minimum facilities. Taking these issues into consideration, the authors have developed a prototype of a Low-Cost Infection Containment Chamber (LCICC) within which autopsies or sample collection from suspected or confirmed highly infectious cadaver can be performed. This innovation could provide infectious disease experts and pathologists a safer alternative to collect specimens to aid in the management outbreaks of highly infectious diseases.

9.
Tourism and Hospitality ; 3(1):47, 2022.
Article in English | ProQuest Central | ID: covidwho-1818202

ABSTRACT

While the COVID-19 pandemic evolves and new variants emerge, destinations and cities look to tourism recovery, cautiously rebooting and re-opening borders. Since the start of the pandemic, dramatic lockdowns have been employed, resulting in dire economic and social consequences to the tourism and hospitality industry and creating the need for a more feasible and sustainable response in the post-pandemic era. Pandemic vigilance and resilience at the societal level have become key in pandemic preparedness. However, due to the complexity of managing COVID-19, no clear cross-disciplinary collaborative framework for tourism recovery has been developed. Cross-sector collaboration to collectively integrate resources, capabilities, and experiences should be prioritised to spearhead tourism recovery plans. With insight on public health, pandemic preparedness, and community access, we hypothesised that cross-industry collaboration between the tourism industry and the pharmacist profession is relevant to the measures adopted for recovery from the COVID-19 pandemic. To examine this hypothesis, this study aimed to explore perceptions from key stakeholders in the tourism and the pharmacist sectors on cross-industry collaboration towards COVID-19 management and the “know-how” in developing, adopting, and advancing such a partnership. This exploratory study adopts and advances the ‘Four Cs’ conceptual framework of communication, cooperation, coordination, and collaboration. In terms of our hypothesis, interview responses with tourism executives and CPs confirm the framework’s suitability and the importance of an interdisciplinary collaborative approach between CPs and the tourism sector to craft a sustainable pathway to recovery from COVID-19 and future pandemic measures as borders re-open and international mobility increases. A tourism recovery strategy from this pandemic can occur more judiciously through a collaborative partnership with an extensive network of pharmacists within communities and popular tourism sites, as CPs have valuable healthcare resources and the ability to track and communicate healthcare alerts to tourism destination recovery efforts.

10.
Gastroenterology Insights ; 13(1):77, 2022.
Article in English | ProQuest Central | ID: covidwho-1818066

ABSTRACT

(1) Background: Currently available guidelines require upper gastrointestinal (GI) endoscopy with biopsy sampling for adult celiac disease (CD) diagnosis. Based on the pediatric experience, there has been a growing interest if serology-based diagnosis would be possible for adult CD also. Our aim was to analyze the associated upper GI tract lesions in newly diagnosed CD patients, to see if significant associated pathology is detected during index endoscopy, which might impact patient management not related to CD. (2) Methods: We performed a retrospective analysis of newly diagnosed CD cases diagnosed over a period of 7 years (2014–2020). Demographic, clinical, laboratory, endoscopy and histopathology data were collected from the patients’ charts. Diagnosis was set according to ACG Guideline 2013. (3) Results: Altogether 79 patients were recruited for this study purpose, 75.9% female, median age 39 years. All patients had positive CD-specific serology and atrophic mucosal injury in duodenal biopsy samples. Besides villous atrophy, associated endoscopic findings were detected in 42/79 (53.16%) of patients. Most of the gastric lesions were minor endoscopic findings—small sliding hiatal hernias, non-specific chronic gastritis, but we also found two cases of peptic ulcers, one case of metaplastic gastritis, six cases of atrophic gastritis and one subepithelial lesion. Only one patient had changes in the duodenum except CD-related findings—an inflammatory polyp in the duodenal bulb. No malignancies were found. (4) Conclusions: In our cohort, there was a significant number of newly diagnosed CD patients who had associated lesions during the index upper GI endoscopy, but most of them were minor endoscopic findings.

11.
PLoS One ; 17(4), 2022.
Article in English | ProQuest Central | ID: covidwho-1817501

ABSTRACT

Objective To assess the levels of stress, burnout, and job satisfaction among mental healthcare professionals in Jeddah City, Saudi Arabia. Methods A cross-sectional study was conducted on mental healthcare professionals in Jeddah between January 2017 and October 2018. Sociodemographic characteristics and levels of stress, burnout, and job satisfaction were assessed using the Perceived Stress Scale-14 (PSS-14), Maslach Burnout Inventory (MBI), and Job Satisfaction Scale (JSS). Descriptive statistics were used. Independent sample t-test, one-way ANOVA, Mann-Whitney, and Kruskal-Wallis tests were conducted to assess for effects of demographic variables on the perceived stress score, emotional exhaustion (EE) score, depersonalization (DP) score, professional accomplishment (PA) score, and the job satisfaction score (JSS). Results A total of 107 participants were included (50.5% men;49.5% women) with response rate of 79.2%. Prevalence of stress was 56.1%. High levels of emotional exhaustion and depersonalization were present among 41 (38.3%) and 26 (24.3%) of the respondents, respectively, while high score of low personal accomplishment were present among 61 (57%) respondents. In terms of job satisfaction, 25 (23.4%) were satisfied and 74 (69.2%) were indecisive. Male participants’ emotional exhaustion score (27±12) was significantly higher than females (22 ±10), (t(105) = 1.99, p-value = 0.049). Also, participants with a monthly income above SR 20,000 had significantly higher total job satisfaction (p-value = 0.041). Conclusions Our findings suggest rates of stress and burnout among mental health professionals that warrant attention, with less than one-quarter of the participants being satisfied with their jobs. Further studies are needed to expand the findings and to explore the contributing factors. Additionally, interventions should be established by authorities to address the increasing rates of stress and burnout.

12.
PLoS One ; 17(4), 2022.
Article in English | ProQuest Central | ID: covidwho-1817487

ABSTRACT

Introduction Reduced rates of help seeking by those who self-harmed during the COVID-19 pandemic have been reported. Objectives To understand changes in healthcare service contacts for self-harm during the COVID-19 pandemic across primary, emergency and secondary care. Methods This retrospective cohort study used routine electronic healthcare data for Wales, United Kingdom, from 2016 to March 14, 2021. Population-based data from primary care, emergency departments and hospital admissions were linked at individual-level. All Welsh residents aged ≥10 years over the study period were included in the study. Primary, emergency and secondary care contacts with self-harm at any time between 2016 and March 14, 2021 were identified. Outcomes were counts, incidence, prevalence and proportion of self-harm contacts relative to all contacts in each and all settings, as well as the proportion of people contacting one or more settings with self-harm. Weekly trends were modelled using generalised estimated equations, with differences between 2020 (to March 2021) and comparison years 2016–2018 (to March 2017–2019) quantified using difference in differences, from which mean rate of odds ratios (μROR) across years was reported. Results The study included 3,552,210 individuals over the study period. Self-harm contacts reduced across services in March and December 2020 compared to previous years. Primary care contacts with self-harm reduced disproportionately compared to non-self-harm contacts (μROR = 0.7, p<0.05), while their proportion increased in emergency departments during April 2020 (μROR = 1.3, p<0.05 in 2/3 comparison years) and hospital admissions during April-May 2020 (μROR = 1.2, p<0.05 in 2/3 comparison years). Despite this, those who self-harmed in April 2020 were more likely to be seen in primary care than other settings compared to previous years (μROR = 1.2, p<0.05). A lower proportion of those with self-harm contacts in emergency departments were subsequently admitted to hospital in December 2020 compared to previous years (μROR = 0.5, p<0.05). Conclusions These findings suggest that those who self-harmed during the COVID-19 pandemic may have been less likely to seek help, and those who did so faced more stringent criteria for admission. Communications encouraging those who self-harm to seek help during pandemics may be beneficial. However, this needs to be supported by maintained provision of mental health services.

13.
PLoS One ; 17(4), 2022.
Article in English | ProQuest Central | ID: covidwho-1817483

ABSTRACT

Respiratory infectious diseases pose a serious threat worldwide, and novel antiviral materials are highly demanded. Photocatalytic nanoparticles have been developed to inhibit indirect transmission of pathogens by acting as surface coating materials. During development of such antiviral materials, researchers use bacteriophages as model viruses due to their safety and experimental efficiency. Screening methods are used to identify potential antiviral materials, and better screening technologies will accelerate the discovery of antiviral treatments. In this study, we constructed a novel platform to evaluate antiviral activity of surface coating materials using the M13 bacteriophage and phagemid system derived from phage display technology. The evaluation results generated by this system for the two tested antiviral materials were comparable to those for the materials tested on the Qβ bacteriophage and influenza virus using traditional screening methods. The experimental system developed in this study provides rapid and effective screening and can be applied to the development of novel antiviral materials.

14.
Respirology ; 27(SUPPL 1):40, 2022.
Article in English | EMBASE | ID: covidwho-1816633

ABSTRACT

Introduction/Aim: Pulmonary tele-rehabilitation (PTR) became a way of providing exercise training and education for people with respiratory conditions during the COVID- 19 pandemic. To determine if PTR was safe, improved exercise capacity, breathlessness and health-related quality of life. Methods: Retrospective observational study. Participants had COPD, bronchiectasis, interstitial lung disease, asthma or recent lung surgery. As well as access to WIFI and a home device for videoconferencing. Outcomes: five time sitto- stand (5STS), 1 min sit-to-stand (1MinSTS);St George's Respiratory Questionnaire (SGRQ);COPD assessment test (CAT);Hospital Anxiety and Depression Scale (HADS);Modified Medical Research Council (mMRC) dyspnoea scale, number of adverse events. PTR used a zoom platform, ran for 40 min twice per week for 8 weeks, with a maximum of 10 participants in each class. An experienced physiotherapist led the exercise sessions with support from physiotherapy students. Results: Seventy-five people (66 females) commenced PTR [mean (SD): Age 67 (11) years, FEV1 63 (20) % pred] and 52 (70%) completed. Statistically significant improvement (mean change (SD) [95% CI]) for 5STS: -4 (7) [-6 to -1] s;1MinSTS: 5 (8) [2-9] times;SGRQ total: -7 (12) [-11 to -3] points;mMRC: -0.3 (0.7) [-0.6 to -0.7] score;CAT: -2.4 (6) [-4 to -0.5] score. No adverse events were reported. Conclusions: PTR improved exercise capacity, healthrelated quality of life and dyspnoea with no adverse events reported. Outpatient-based PR remains the gold standard;however, PTR could be provided during COVID lockdowns and incorporated as a flexible option for people who find it difficult to attend outpatient-based PR.

15.
Brain Injury ; 36(SUPPL 1):1, 2022.
Article in English | EMBASE | ID: covidwho-1815740

ABSTRACT

Objective: A Research Prioritization Exercise (RPE) was conducted to determine research focus for the coming years in an adult neurorehabilitation service. As best practice guidelines in health research highlight that Public and Patient Involvement (PPI) should be a key component, particular emphasis was placed on including the perspectives of clients and family members in the RPE. Design: Due to COVID-19 restrictions, the planned focus groups with clients and family members were altered to telephone and zoom contact and questionnaires were distributed through an online system. Method: Following a literature review and scoping, a research prioritization questionnaire to all stakeholders was designed with input from clients on the content. The results were analyzed with client and family member involvement. Results: The following research priority themes were agreed from 259 responses: 'Effective rehabilitation,' 'Access to services and the rehabilitation pathway,' 'The impact of brain injury' and 'The facts and figures.' Clients and families suggested the themes were interlinked. The involvement of clients throughout the research process, rather than as solely 'research participants,' was highlighted as crucial. Conclusions: The themes now form the core part of our research work for this strategic phase of our service. Our clients and their families are at the center of these priorities. Researchers will have to provide evidence of their PPI plan to our Ethics Committee and we will examine how we can support our clients in this process of being more prominent stakeholders in service research.

16.
The New England Journal of Medicine ; 386(17):1627-1637, 2022.
Article in English | ProQuest Central | ID: covidwho-1815679

ABSTRACT

BackgroundNeonatal endotracheal intubation often involves more than one attempt, and oxygen desaturation is common. It is unclear whether nasal high-flow therapy, which extends the time to desaturation during elective intubation in children and adults receiving general anesthesia, can improve the likelihood of successful neonatal intubation on the first attempt.MethodsWe performed a randomized, controlled trial to compare nasal high-flow therapy with standard care (no nasal high-flow therapy or supplemental oxygen) in neonates undergoing oral endotracheal intubation at two Australian tertiary neonatal intensive care units. Randomization of intubations to the high-flow group or the standard-care group was stratified according to trial center, the use of premedication for intubation (yes or no), and postmenstrual age of the infant (≤28 or >28 weeks). The primary outcome was successful intubation on the first attempt without physiological instability (defined as an absolute decrease in the peripheral oxygen saturation of >20% from the preintubation baseline level or bradycardia with a heart rate of <100 beats per minute) in the infant.ResultsThe primary intention-to-treat analysis included the outcomes of 251 intubations in 202 infants;124 intubations were assigned to the high-flow group and 127 to the standard-care group. The infants had a median postmenstrual age of 27.9 weeks and a median weight of 920 g at the time of intubation. A successful intubation on the first attempt without physiological instability was achieved in 62 of 124 intubations (50.0%) in the high-flow group and in 40 of 127 intubations (31.5%) in the standard-care group (adjusted risk difference, 17.6 percentage points;95% confidence interval [CI], 6.0 to 29.2), for a number needed to treat of 6 (95% CI, 4 to 17) for 1 infant to benefit. Successful intubation on the first attempt regardless of physiological stability was accomplished in 68.5% of the intubations in the high-flow group and in 54.3% of the intubations in the standard-care group (adjusted risk difference, 15.8 percentage points;95% CI, 4.3 to 27.3).ConclusionsAmong infants undergoing endotracheal intubation at two Australian tertiary neonatal intensive care units, nasal high-flow therapy during the procedure improved the likelihood of successful intubation on the first attempt without physiological instability in the infant. (Funded by the National Health and Medical Research Council;Australian New Zealand Clinical Trials Registry number, ACTRN12618001498280.)

17.
BJPsych International ; 19(2):53-55, 2022.
Article in English | ProQuest Central | ID: covidwho-1817331

ABSTRACT

Using data from the Centers for Disease Control and Prevention (Wide-ranging Data for Epidemiologic Research) and the National Center for Health Statistics, they calculated drug overdose death rates by race and ethnicity for 1999–2020 in the USA. Friedman JR, Hansen H. Evaluation of increases in drug overdose mortality rates in the US by race and ethnicity before and during the COVID-19 pandemic. The researchers isolated live organisms from tissues and using immunohistochemical methods showed that this pathogen can, via the olfactory and trigeminal nerves, reach the olfactory bulb and brain in mice within 72 h. Importantly they also showed that this resulted in dysregulation of key pathways known to be involved in Alzheimer's disease at 7 and 28 days following inoculation. Chacko A, Delbaz A, Walkden H, Basu S, Armitage CW, Eindorf T, Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer's disease risk.

18.
Legal Information Management ; 22(1):45-48, 2022.
Article in English | ProQuest Central | ID: covidwho-1815446

ABSTRACT

This opinion article, by Channarong Intahchomphoo and Christian Tschirhart, explains the evolution of data and how it becomes useful information and then insightful knowledge. In the current era we are witnessing a high increase in the development and adaptation of artificial intelligence (AI) in society. AI technologies have the ability to process large volumes of data and information to help in finding insightful knowledge. However, AI is not perfect and there are ethical concerns, particularly when unintended negative consequences result from it;this paper also discusses ethical concerns currently confronting our society related to the freedom of expression and hate speech issues with AI. Importantly, this paper notes that governments are working to find ways to regulate social media and internet companies through legal channels as governments are no longer confident in the ability of social media and internet companies to self-regulate and thereby to guide society on what content is right or wrong. This is a critical new development in internet and AI governance that information and technology professionals and public and private organizations need to monitor closely the situation as it evolves.

19.
The Lancet Psychiatry ; 9(5):349, 2022.
Article in English | EMBASE | ID: covidwho-1815335
20.
Lancet Oncol ; 23(5):e208, 2022.
Article in English | ProQuest Central | ID: covidwho-1815331

ABSTRACT

The absence of any serious plan to tackle workforce shortages is threatening efforts towards improving early cancer diagnosis and overall survival rates in England, a crucial report from the Health and Social Care Committee has warned. None of the ambitions to tackle the pandemic backlog, improve early diagnosis, or ensure the provision of prompt treatment will be possible without addressing gaps in the numbers of clinical oncologists, consultant pathologists, radiologists, and specialist cancer nurses, according to the Committee's independent expert panel. According to the report, the Committee has frequently recommended the overhaul of workforce planning with independent projections of need, but the Government has failed to implement this strategy.

SELECTION OF CITATIONS
SEARCH DETAIL