Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 253
Filter
1.
2022 International Mobile and Embedded Technology Conference, MECON 2022 ; : 617-620, 2022.
Article in English | Scopus | ID: covidwho-1840276

ABSTRACT

Coronavirus diseases is a contagious transmissible infectious malady rooted by the SARS-CoV-2 virus and it mostly affects the lungs thereby causing a global health care problem. Coronavirus triggers respiratory tract infection by infecting upper respiratory tract consisting of sinuses, nose, and throat or lower tract of respiratory system that includes windpipe and lungs. WHO proclaimed the COVID-19 outbreak a global epidemic. To control the spreading of novel Coronavirus, early detection and cure is mandatory. Although RT-PCR test is used to detect the infected humans but owing to colossal demand RT-PCR kits are now limited, and its low reliability made way for implementation of radiographic procedures such as X-Rays and Computed Tomography-Scan for symptomatic purposes. These come with a great specificity for diagnosing and detecting Covid-19 instances. This study suggests adopting a Deep Learning technique to automate the diagnosis of COVID19 infection using CT scans of patients for explicit identification of Covid-19. CNN namely Densenet, Inception and Xception networks or architectures are used in a deep learning architecture to distinguish human beings based on whether confirmed positive or not for COVID-19 infection. These networks are then collated on the ground of their accuracy and the outcomes procured from various CNN models are analysed to obtain a robust system. © 2022 IEEE.

2.
J Infect Dis ; 2022 May 07.
Article in English | MEDLINE | ID: covidwho-1831187

ABSTRACT

Health jurisdictions have seen a near-disappearance of Respiratory Syncytial Virus (RSV) during the first year of the COVID-19 pandemic. Over a corresponding period, we report a reduction in RSV antibody levels and neutralization in women and infants one year into the COVID-19 pandemic (February - June 2021) compared to earlier in the pandemic (May - June 2020), in British Columbia (BC), Canada. This supports that humoral immunity against RSV is relatively short-lived and its establishment in infants requires repeated viral exposure. Waned immunity in young children may explain the inter-seasonal resurgence of RSV cases in BC as seen also in other countries.

3.
Chinese Journal of Zoonoses ; 37(12):1135-1140, 2021.
Article in Chinese | GIM | ID: covidwho-1818310

ABSTRACT

This study aimed to evaluate the etiological and clinical characteristics of acute upper respiratory tract infections in children from GuangZhou, China. A total of 2 665 nose swabs specimen collected from children with acute upper respiratory tract infections from Zhujiang Hospital, Southern Medical University, Guangzhou, China during November 2009 to September 2015 were enrolled in this study. There were 1 566 virus positive responses were detected in samples from 2665 child patients with acute upper respiratory infections, with the positive rate of 58.8%. The positive rates were 22.5% for respiratory sycytial virus (RSV), 13.0% for rhinovirus (HRV), 9.0% for influenza virus (FLU), 7.6% for parainfluenza virus (PIV), 6.1% for adenovirus (AdV), 4.0% for human metapneumovirus (HMPV), 3.7% for human coronavirus (HCOV), 3.5% for human Bocavirus (HBOV). There was statistical significant in the detection rates of 8 respiratory viruses in different seasons, with the highest in spring, followed by summer and winter, and lowest in autumn. The respiratory virus infection rate of children gradually decreased with age, with a positive detection rate of 67.0% between children aged 0-3 years. And the respiratory virus detection rate of boys was significantly higher than that of girls. The co-infection rates were higher in child patients aged 0-3 years, and were higher during spring and summer than that of autumn and winter. Cough is the main clinical symptom of acute upper respiratory virus infection, followed by sputum and runny nose. The clinical symptoms are different in children between 8 respiratory virus infections. This study increases our knowledge of the etiological and clinical characteristics of these 8 common respiratory viruses among children with respiratory tract infections. Which might also provide relevant data to guide clinical treatment and prevention.

4.
J Clin Transl Res ; 8(2): 156-159, 2022 Apr 29.
Article in English | MEDLINE | ID: covidwho-1813044

ABSTRACT

Background: There has been extensive research showing that upper respiratory tract infections (URTIs), such as the common cold and influenza, can impair mental performance. Much of this research has involved studies of experimentally induced URTIs or laboratory studies of naturally occurring illnesses. The results from this research have implications for performance at work and in education. Aims: The present article presents a case study of the association between URTIs and academic performance and reports the use of such information as an extenuating circumstance for poor performance. Methods: The paper describes the poor performance of a primary school student taking the 11+ examination, which determines the choice of the future secondary school. Evidence suggested that it was plausible that the student was incubating an URTI at the time of the examination. Other possible infections, such as COVID, were ruled out. An appeal was made based on the possible association between incubating an URTI and unusually poor examination performance. Results: The appeal was supported by the adjudicating committee and the student was allowed a place in the preferred secondary school. Conclusions: This case study shows that information about the association between URTIs and mental performance can be used as an extenuating circumstance that can plausibly account for poor academic performance. This can form the basis of the future appeals and recommendations for the type of evidence needed to make such claims are made. Relevance for Patients: URTIs are frequent, common, and a cause of absence from education and work. They may also impair performance, with effects not being restricted to the time the person is symptomatic. They may also increase susceptibility to the negative effects of stress and fatigue.

5.
Natural Volatiles & Essential Oils ; 8(5):2689-2707, 2021.
Article in English | CAB Abstracts | ID: covidwho-1813080

ABSTRACT

The growth and development of children is very important, as this would form the foundation for the quality of future generations in the nation. The slightest developmental disorders in infancy, if not detected and not handled properly will lead to a bad impact. Various genetic and environmental factors influence Toddler growth and development. Purpose: To distinguish the description of the risk factors related to child growth and development. Method: This research uses quantitative method. The design of the research is based on a cross-sectional approach in the analysis survey design. In the study, all toddlers under 59 month old were collected using a total of 366 samples in 2020 at the Ngalang Village, Gedangsari public health center and Gunungkidul Regency. Data analysis used univariate analysis of frequency distribution.

6.
Natural Volatiles & Essential Oils ; 8(5):4210-4216, 2021.
Article in English | CAB Abstracts | ID: covidwho-1812953

ABSTRACT

The global current scenario shows that COVID-19 has spread worldwide and drugs prescribed to treat the disease are under study. The imperative requirement of drugs to treat COVID-19 has made significant changes in the pharmacological industry. Discovering drugs for such a pandemic has been a crucial target, with standardisation, preclinical and clinical studies being conducted in all possible age groups. Siddha medicines have found their way in the treatment of COVID-19 largely and increasingly been accepted worldwide. Among such constant trials, implementation of the molecular docking process has helped to reveal the importance of different Siddha medicines in the first place as therapeutics to COVID-19. The Government bodies have also recommended these antiviral compounds to treat symptoms such as cold, fever, breathing difficulty and sore throat. This study aims to focus on to gather awareness on the impact of various Siddha medicines and their insights into molecular level to fight against Coronaviruses. As a result of this review, it was found that the phytochemical compounds present in various siddha medicines such as Kabasura Kudineer, Adathodai Kudineer, Maramanjal Kudineer and so on, have been docked with the possible target proteins of SARS-CoV-2 virus to disclose that they have potential action on the virus and declare to act as the candidate drugs in COVID-19 treatment.

7.
Natural Volatiles & Essential Oils ; 8(5):816-821, 2021.
Article in English | GIM | ID: covidwho-1812797

ABSTRACT

Lymphocyte leukemia/lymphoma (ATLL) is a fringe T-cell harm brought about by human T-cell leukemia infection type. Lymphocyte leukemia (ATL) is an exceptionally forceful developed T-cell neoplasm related with human T-cell lymphotropic infection type 1 (HTLV-1) contamination, which influences around 10 million individuals on the planet. Of them, roughly 1-5% at last creates indicative ATL. Patient history: A 15 years male was admitted in AVBRH with complaint of fever, decrease appetite from 1 month, vomiting with blood tinged food particles and melena. Patient was diagnosed case of T-cell variant ALL. Before coming to AVBRH he was admitted to GMC Nagpur where he was diagnosed to had T-cell ALL with aberrant expression of CD10. He also had generalised lymphadenopathy and massive hepatosplenomegaly. He was advised blood transfusion but gives no H/O the same. Then he was discharged. After that patient developed malaena and blood tinged vomiting for which he came to AVBRH for further management. After his arrival, he was covid-19 positive so shifted to COVID ward. After two weeks, RTPCR status was negative then he shifted to PICU. . Clinical finding: The patient had done all necessary investigations by physician order. Medical Management: Patient was treated with IV. Fluids, platelet transfusion, chemotherapy, steroids, calcium gluconate, antibiotics, antacid, vit c and multivitamins. Nursing management: Administered fluid replacement i.e. D5, chemotherapy, platelet transfusion monitored all vital signs half hourly.

10.
Epidemiol Infect ; 150: e79, 2022 Mar 21.
Article in English | MEDLINE | ID: covidwho-1805520

ABSTRACT

Hand hygiene is a simple, low-cost intervention that may lead to substantial population-level effects in suppressing acute respiratory infection epidemics. However, quantification of the efficacy of hand hygiene on respiratory infection in the community is lacking. We searched PubMed for randomised controlled trials on the effect of hand hygiene for reducing acute respiratory infections in the community published before 11 March 2021. We performed a meta-regression analysis using a Bayesian mixed-effects model. A total of 105 publications were identified, out of which six studies reported hand hygiene frequencies. Four studies were performed in household settings and two were in schools. The average number of handwashing events per day ranged from one to eight in the control arms, and four to 17 in the intervention arms. We estimated that a single hand hygiene event is associated with a 3% (80% credible interval (-1% to 7%)) decrease in the daily probability of an acute respiratory infection. Three of these six studies were potentially at high risk of bias because the primary outcome depended on self-reporting of upper respiratory tract symptoms. Well-designed trials with an emphasis on monitoring hand hygiene adherence are needed to confirm these findings.


Subject(s)
Epidemics , Hand Hygiene , Respiratory Tract Infections , Bayes Theorem , Hand Disinfection , Humans , Respiratory Tract Infections/epidemiology , Respiratory Tract Infections/prevention & control
11.
Biomedica ; 42(2):1-12, 2022.
Article in English, Spanish | Scopus | ID: covidwho-1791916

ABSTRACT

Introduction: Incluir Objective: Estimate the incidence of acute respiratory symptoms and Covid-19 in children from public schools in Bogotá Colombia during second semester of 2020. Materials and methods: Telephone survey conducted in over 5000 scholar children. Antecedents and use of health services were informed. Descriptive statistics were used. Results: A total of 151470 persons-day were accounted for an incidence rate of 157.8x 100000 people, almost three times the reported by official surveillance system in the city. Conclusion: Lacks in diagnosis and consultation in children were found when compared to general population. Further research is needed to elucidate the true burden of disease among children. © 2022

12.
Front Pediatr ; 10: 840008, 2022.
Article in English | MEDLINE | ID: covidwho-1792984

ABSTRACT

Background: In children and adults with acute respiratory tract infections (ARTI), elevations of serum liver enzyme activities are frequently observed in clinical practice. However, epidemiological data particularly in the pediatric population are very limited. The aim of this study was to assess the incidence of hepatic involvement, to identify the viruses and to analyze risk factors in children and adolescents with ARTI in a real-world setting. Methods: We report on a prospective, multicenter, non-interventional study with 1,010 consecutive patients aged 1-17 years with ARTI who consulted a physician within 5 days after onset of symptoms. Laboratory blood tests and PCR virus detection in nasopharyngeal lavage were performed at first presentation and after 3-7 days. Patients with elevated activities of serum liver enzymes (ASAT, ALAT, and γ-GT) were determined in local laboratories and values were normalized by dividing by the individual upper limit of the normal range (ULN). The resulting index (<1 means below ULN, >1 means above ULN) allowed to compare results from laboratories with different reference ranges. Results: Laboratory test results of 987 patients were available at first visit. 11.1% (95% CI: 9.2-13.3%) exhibited an elevation of ASAT, ALAT, and/or γ-GT activities. Virus DNA or RNA was identified in nasopharyngeal lavages of 63% of the patients. 12.2% of patients with positive PCR and 9.7% of those with negative PCR (p = 0.25) had elevated serum liver enzyme activities. The highest rates were observed in patients with a positive result for influenza B virus (24.4%) followed by human metapneumovirus (14.6%), and human coronavirus (others than SARS-CoV-2) (13.6%). The rate of children and adolescents with ARTI and elevation of serum liver enzyme activities correlated with the virus species and with overweight of the patients but did not differ in patients with or without previous medication intake. Conclusion: Elevated enzyme activities are present in about 10% of children and adolescents with ARTI. In our cohort, these elevations were mild to moderate; probably resulting from an inflammation process with hepatic involvement.

13.
Biomedica ; 42(2):1-34, 2022.
Article in Spanish | Web of Science | ID: covidwho-1790166

ABSTRACT

Introduction: The inappropriate use of antibiotics is associated with greater antimicrobial resistance, health care costs, adverse events, and worse clinical outcomes. Objective: To determine the prescription patterns and approved and non-approved indications of macrolides in a group of patients from Colombia. Materials and methods: a cross-sectional study on the indications for the use of macrolides in outpatients based on a drug dispensing database of approximately 8.5 million people affiliated with the Colombian Health System. Sociodemographic, pharmacological and clinical variables were considered. Results: 9344 patients were identified with some macrolide prescription, with a median age of 40.1 years [interquartile range: 27.1-53.3 years] and 58.3% women. The most commonly prescribed macrolide was azithromycin (38.8%) and the most frequently found uses were Helicobacter pylori infection (15.9%) and pneumonia treatment (15.8%). 31.3% of prescriptions were used for unapproved indications, with the common cold (7.8%), COVID-19 (4.0%), and acute bronchitis (3.5%) standing out. Reside in the Caribbean region (OR:1.17;95%CI:1.05-1.31), dental prescriptions (OR:2.75;95 degrees ACI:1.91-3.96), have chronic respiratory comorbidities (OR:1.30;95 degrees ACI:1.08-1.56), prescribe erythromycin (OR:3.66;95%CI:3.24-4.14) or azithromycin (OR:2.15;95%CI:1,92-2.41), were associated with a higher probability of receiving them for unapproved indications, but being between 18-64 years old (OR:0.81;95 degrees ACI:0.71-0.93), 65 or more years (OR:0.77;95%CI:0.63-0.94) and residing in Bogota-Cundinamarca (OR:0.74;95%CI:0.65-0.85) reduced this risk. Conclusions: Most patients have received macrolides for respiratory tract infections;however, erythromycin and azithromycin are being used in unapproved indications in people under 18 years of age, and those with chronic respiratory diseases.

14.
Natural Volatiles & Essential Oils ; 9(1):766-775, 2022.
Article in English | GIM | ID: covidwho-1787227

ABSTRACT

SARS-CoV-2 is an emerging pathogen first reported in China and rapidly spreads throughout the world. The current study focused on the prevalence of symptoms, leukocytosis, leukocytopenia, thrombocytopenia, and comorbidity in patients resulted positive for COVID-19. About 200 patients were enrolled in the study first screened by ICT and then confirmed by RT-PCR. All the patients have symptoms fever, sore throat and dry cough. However 180 (90%) patients experienced tiredness, aches and pain all over the body in 193 (96%), diarrhea in 160 (80%), conjunctivitis in 64 (32%), headache in 177 (88%), loss of taste and smell in 49 (24%), a rash on skin, or discoloration of fingers or toes in 54 (27%), shortness of breath in 12 (8%), chest pain or pressure in 16 (8%), loss of speech and movement in 4 (2%) patients. 78 (39%) patients were found having co-infections including 23 (29.5%) patients have liver infection, 14 (17.9%) were kidney patients, 16 (20.5%) were heart patients and 25 (32%) were diabetic patients. Leukocytosis were found in 76 (97%) out 78 comorbid patients, while in only 2 (2.6%) non-comorbid patients had leukocytosis. Leukopenia were detected in 122 (61%) non-morbidpatients out of 200 COVID-19 patients. Thrombocytopenia were detected in 118 (59%) COVID-19 patients. The patients with previous cardiovascular diseases and other comorbid conditions may face greater risk of developing the disease into severe form. 51-60 years of individuals are at high risk of getting infection. The hematologic changes are associated with COVID-19 includes thrombocytopenia, leukocytosis, and leukocytopenia.

15.
Front Microbiol ; 13: 804700, 2022.
Article in English | MEDLINE | ID: covidwho-1785370

ABSTRACT

The social distancing measures adopted during the coronavirus disease 2019 (COVID-19) pandemic led to a profound change in the behavioral habits of the population. This study analyzes the impact of restriction measures on the shaping of the epidemiology of common winter respiratory pathogens in the pediatric population of northeast of Italy. From August 2020 to March 2021, a total of 1,227 nasopharyngeal swabs from symptomatic pediatric patients were tested for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A and B, adenovirus, other coronaviruses, parainfluenza virus 1-4, enterovirus, bocavirus, metapneumovirus, respiratory syncytial virus, rhinovirus, Bordetella pertussis, Bordetella parapertussis, and Mycoplasma pneumoniae. To relate virus positivity with the clinic characteristics of the subjects enrolled, multinomial logistic models were estimated. SARS-CoV-2 was detected in 5.2% of the children; fever resulted as risk factor for infection [relative risk ratio (RRR) = 2.88, p = 0.034]. Rhinovirus was detected in the 40.7% of the subjects, with cough and rhinitis as risk factors (respectively, RRR = 1.79, p = 0.001 and RRR = 1.53, p = 0.018). Other coronaviruses were found in 10.8% of children and were associated to pharyngodynia (RRR = 4.94, p < 0.001). Adenovirus, observed in 11.6% of subjects, showed to have fever as risk factor (RRR = 6.44, p < 0.001). Bocavirus was detected in 3.2% of children. In conclusion, our results showed that social isolation measures had an impact on the circulation of RSV and influenza, although children under the age of 2 were most affected by the other respiratory infections. Therefore, this study highlights the need for continuing surveillance for a delayed spread of RSV and other respiratory pathogens.

16.
Non-conventional in English | WHOIRIS, Grey literature | ID: grc-753821
17.
Jaffna Medical Journal ; 33(2):31-35, 2021.
Article in English | CAB Abstracts | ID: covidwho-1771320

ABSTRACT

Respiratory diseases are common causes of hospital admission in children. Droplet transmission is the primary route of transmition in respiratory infections. The objective was to assess the burden of respiratory diseases on hospital admission of children during this Covid 19 pandemic and to assess the impact of Covid 19 preventive measures on it. An institutional based retrospective descriptive study based on secondary data was carried out at Professorial Paediatric unit Teaching hospital Jaffna. The data was extracted from the electronic patient management system. All the records of children who were primarily diagnosed with respiratory disease during the period of June 2020 to May 2021 were extracted. This data was compared with that of 2017. The total hospital admission has reduced from 4127 to 1049 during the pandemic. There was a significant decrease in total hospital admission during the covid 19 pandemic compared to before the pandemic {t (11.488) = 8.015 p<0.001}. Similarly, there was a significance decrease in the admissions due to respiratory diseases during the covid 19 pandemic {t(11.355) =5.982 p<0.001}. The percentage of respiratory admission has significantly reduced during the pandemic {t (21.997) =5.173 p<0.001}. Hospital admission due to respiratory illness has significantly reduced when compared to total admission during this pandemic. This may be attributed to social distancing, wearing mask and good hand hygiene.

18.
Chinese Journal of School Health ; 43(1):120-122, 2022.
Article in Chinese | GIM | ID: covidwho-1756487

ABSTRACT

Objective: To understand the epidemiological characteristics of an outbreak of respiratory tract infection caused by human metapneumovirus (hMPV) in a primary school in Huzhou City, and to provide scientific reference for the prevention and control of the outbreak of upper respiratory tract infection caused by hMPV in the future.

19.
Arch Argent Pediatr ; 120(2): 99-105, 2022 04.
Article in English, Spanish | MEDLINE | ID: covidwho-1766098

ABSTRACT

INTRODUCTION: Respiratory viruses are the main cause of acute lower respiratory tract infection (ALRTI) in the pediatric population. In March 2020, the World Health Organization declared that the new coronavirus disease 2019 (COVID-19) had reached the pandemic status. Our objective was to describe the impact of COVID-19 pandemic on hospitalizations due to ALRTI at Hospital de Niños Ricardo Gutiérrez (HNRG) and virus circulation. METHODS: Observational, retrospective, and descriptive study of patients hospitalized due to ALRTI comparing 2019 and 2020. RESULTS: In 2020, the rate of hospitalization due to ALRTI decreased by 73%. In 2019, 517 patients with ALRTI were hospitalized; the following viruses were identified in 174: respiratory syncytial virus (RSV) (71.2%), adenovirus (AV) (10.3%), parainfluenza virus (PIV) (9.7%), and influenza virus (FLU) (8.6%). In 2020, 94 patients with ALRTI were hospitalized. Until epidemiological week (EW) 13, cases of ALRTI due to PIV and AV were recorded; in EW 29, there was 1 case of bronchiolitis due to AV and rhinovirus (RV), followed by isolated cases of RV; no ALRTI due to RSV or FLU was recorded. In total, 9 cases of ALRTI due to COVID-19 were recorded: 2 moderate bronchiolitis and 7 focal pneumonia; 1 adolescent with comorbidities died due to COVID-19 pneumonia. In 2020, patients were older and had more comorbidities and prior hospitalizations compared to 2019. Focal pneumonia prevailed. CONCLUSIONS: In 2020, the rate of hospitalization due to ALRTI decreased significantly compared to 2019, with the absence of seasonal respiratory virus circulation in the pediatric population.


Introducción. Los virus respiratorios son la principal causa de infección respiratoria aguda baja (IRAB) en la población pediátrica. En marzo de 2020, la Organización Mundial de la Salud declaró el estado de pandemia de la enfermedad por el nuevo coronavirus 2019 (COVID-19) con un impacto global elevado. El objetivo de este estudio fue describir el impacto de la pandemia de COVID-19 en las internaciones por IRAB en el Hospital de Niños Ricardo Gutiérrez (HNRG) y la circulación viral. Métodos. Estudio observacional, retrospectivo y descriptivo de pacientes internados por IRAB, comparando los años 2019 y 2020. Resultados. En 2020, la tasa de hospitalización por IRAB se redujo un 73 % en el HNRG (575,1/10 000 en 2019 y 155,3/10 000 en 2020). En 2019 se internaron 517 pacientes con IRAB; en 174 se identificaron los virus: sincicial respiratorio (71,2%), adenovirus (AV) (10,3%), parainfluenza (PIF) (9,7 %) e influenza (FLU) (8,6 %). En 2020, se hospitalizaron 94 pacientes con IRAB. Hasta la semana epidemiológica (SE) 13 se registraron casos de IRAB por PIF y AV; en la SE 29 un caso de bronquiolitis por AV y rinovirus (RV), seguido de casos aislados de RV; no hubo IRAB por VSR ni por FLU. Se registraron 9 casos de IRAB por COVID-19: 2 bronquiolitis moderadas y 7 neumonías focales; con un adolescente fallecido por neumonía por COVID-19 con comorbilidades. En 2020, los casos presentaron mayor edad, más comorbilidades e internaciones previas en comparación con el 2019. La neumonía focal fue la presentación clínica predominante. Conclusión. En 2020, la tasa de hospitalización por IRAB se redujo significativamente en comparación con el año anterior, con ausencia de circulación de virus respiratorios estacionales en la población asistida en nuestro centro.


Subject(s)
COVID-19 , Viruses , Adolescent , COVID-19/epidemiology , Child , Hospitals, Pediatric , Humans , Pandemics , Retrospective Studies
20.
Electronic Journal of General Medicine ; 19(3):7, 2022.
Article in English | Web of Science | ID: covidwho-1761631

ABSTRACT

Background: Globally, micronutrient use has increased over the last few decades for disease prevention and holistic health. This article has analyzed the worldwide search trends of micronutrients in the Google Trends (GT) platform to understand the significance and correlation of search trends, comparing the search interests across countries and recognizing the factors involved. Methods: Specific search terms were used to identify the search trends of micronutrients in the GT platform. Statistical analysis was done to evaluate the outcomes of significance and correlation of search terms from 2004 to 2021 by using statistical softwares. Results: There was a rise in searches for micronutrients vitamin D, vitamin C, zinc, & iron from 2004 to June 2021 with a steep increase during 2020 correlating with the COVID-19 pandemic. A stable search has been reported in iron searches. Significance and correlation of vitamin D, vitamin C, zinc, & iron over the years and search interest popularity score of countries for micronutrient searches have been described. Conclusions: The GT tool can be a necessary tool for healthcare communities and government sectors to understand people's interests, necessities and respond to their concerns accordingly, thus helping us promote population-centric awareness and achieve better evidence-based outcomes.

SELECTION OF CITATIONS
SEARCH DETAIL