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Aims Bioengineering ; 9(2):93-101, 2022.
Article in English | Web of Science | ID: covidwho-1798847


The spread of infections, as in the coronavirus pandemic, leads to the desire to perform disinfection measures even in the presence of humans. UVC radiation is known for its strong antimicrobial effect, but it is also harmful to humans. Visible light, on the other hand, does not affect humans and laboratory experiments have already demonstrated that intense visible violet and blue light has a reducing effect on bacteria and viruses. This raises the question of whether the development of pathogen-reducing illumination is feasible for everyday applications. For this purpose, a lighting device with white and violet LEDs is set up to illuminate a work surface with 2,400 lux of white light and additionally with up to 2.5 mW/cm2 of violet light (405 nm). Staphylococci are evenly distributed on the work surface and the decrease in staphylococci concentration is observed over a period of 46 hours. In fact, the staphylococci concentration decreases, but with the white illumination, a 90% reduction occurs only after 34 hours;with the additional violet illumination the necessary irradiation time is shortened to approx. 3.5 hours. Increasing the violet component probably increases the disinfection effect, but the color impression moves further away from white and the low disinfection durations of UVC radiation can nevertheless not be achieved, even with very high violet emissions.

Infect Dis Clin North Am ; 35(3): 575-607, 2021 09.
Article in English | MEDLINE | ID: covidwho-1340079


All invasive procedures involve contact by a medical device or surgical instrument with a patient's sterile tissue or mucous membranes. The level of disinfection is dependent on the intended use of the object: critical, semicritical, or noncritical. New issues and practices can affect the risk of infection associated with devices and surfaces. Endoscopes continue to represent a nosocomial hazard. The contaminated surface environment in hospital rooms is important in the transmission of health care-associated pathogens. Thoroughness of cleaning must be monitored and no-touch room decontamination technology should be. In general, emerging pathogens are susceptible to currently available disinfectants.

Cross Infection/prevention & control , Delivery of Health Care/organization & administration , Disinfectants , Disinfection/methods , Equipment Contamination/prevention & control , Sterilization/methods , Endoscopes , Equipment and Supplies, Hospital , Hospitals , Humans , Temperature