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1.
Mathematical Thinking and Learning ; JOUR(4):331-335, 24.
Article in English | APA PsycInfo | ID: covidwho-2107022

ABSTRACT

This introductory paper first summarizes the major accomplishments of the literature on data modeling, modeling with software and the integration of statistical and computational thinking in statistical modeling, including how these collective efforts have helped the field evolve. Next, challenges that the field must address and general suggestions for future research are discussed. Finally, it is important to note that the papers in this special issue were in their final editing stages in early to mid-2020, at which time there were an unprecedented confluence of global crises: Covid-19, Civil Unrest over Racism, and Climate Change. Although the papers were written prior to Covid-19, it would be remiss not to discuss some of the important themes cultivated in this special issue in light of current events, particularly around the relationship between the non-neutral nature of data and ideas of data, context and chance in statistical modeling. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

2.
Technol Soc ; 67: 101799, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-2086759

ABSTRACT

The COVID-19 pandemic, and the associated move to remote work and the resulting changes to the normal work routine, have introduced a plethora of new difficulties and challenges for software developers. Recent research has focused on the impact of the COVID-19 pandemic on the developer's wellness, productivity, team collaboration, job satisfaction, and work-life balance. However, research exploring the association between these feelings and team behaviour during such a crisis period has not been previously developed. Moreover, previous research has indicated that organisations are still struggling to understand the pandemic and its relationship with both team behaviour and developer feelings. To address this gap, we analysed how COVID-19 influences a developer's happiness and their feelings of (un)happiness associated with the team's behaviour during the COVID-19 pandemic. A state-of-the-art analysis helped to design a scale that we used in a cross-sectional study of 102 software developers. To test the proposed hypotheses, we conducted exploratory factor analysis and principal component analysis. Our results highlight that happiness positively influences a team's behaviour and that unhappiness negatively affects their work results and productivity. These findings provide software companies and organisations with a better understanding of the importance of team behaviour on individual happiness during crises. These results provide information that managers and companies can use to mitigate potentially negative effects.

3.
2022 Acm/Ieee 44th International Conference on Software Engineering: Software Engineering Education and Training (Icse-Seet 2022) ; : 165-175, 2022.
Article in English | Web of Science | ID: covidwho-2070373

ABSTRACT

The outbreak of the COVID-19 pandemic prohibited radically the collocation and face-to-face interactions of participants in coding bootcamps and similar experiences, which are key characteristics that help participants to advance technical work. Several specific issues are faced and need to be solved when running online coding camps, which can achieve the same level of positive outcomes for participants. One of such issues is how to keep the same level of fun that participants obtained through physical activities and interactions in the face-to-face settings. In this paper, we report on our experience and insights gained from designing and running a fully remote coding camp that exposes high school students to Agile-based Software Engineering practices to enhance their ability to develop high-quality software. To design the online coding camp, we adapted the face-to-face version of the coding camp to keep the same "level of fun", i.e., adaptations aimed at increasing communication, engaging participants, and introducing fun items to reduce fatigue due to prolonged computer use, while preserving the technical curriculum that enables students to attain the learning goals originally planned. The comparison with the results of the face-to-face coding camp shows that we succeeded in keeping the fun alive in the online edition, and the participants of online camp were able to produce the results at the same level of quality in terms of product and process as in the face-to-face edition. From our experience, we synthesize lessons learned, and we sketch some guidelines for educators.

4.
Pakistan Journal of Medical and Health Sciences ; 16(8):88-91, 2022.
Article in English | EMBASE | ID: covidwho-2067739

ABSTRACT

Background: The COVID-19 first surfaced when cluster of pneumonia patients arose in Wuhan, Hubei Province, China. Although the current gold standard for COVID-19 diagnosis is reverse transcriptase-polymerase chain reaction (RT-PCR), chest x-ray (CXR) and computed tomography (CT) play a vital role in sickness diagnosis due to their limited sensitivity and availability. Aim: To evaluate retrospectively the role of CXR, the main radiological findings in it and its diagnostic accuracy in COVID-19 pneumonia. Methods: This is a cross sectional study involving 264 PCR positive COVID-19 patients with their clinical-epidemiological findings admitted at Ziauddin Hospital from May-July 2020. CXRs were taken as digital radiographs in our emergency department's isolation wards using the same portable X-ray device, according to local norms. CXRs were taken in two directions: antero-posterior (AP) and postero-anterior (PA). The hospitals' database had all of the images. To determine the number of radiological findings, multiple radiologists on duty completed an independent and retrospective examination of each CXR. In the event of disagreement, a mutual agreement was reached. SPSS version 20 was used for statistical analysis. Results: We were able to find 264 patients who met our criteria. With a mean age of 56.4214.89, the majority of individuals were determined to be males 189(71.6%) and females 75(28.4%). (Range of 16 to 87 years). 127 patients (48.1%) had severe illness symptoms and were admitted to the ICU, while the remaining 102(38.6%) had mild to moderate disease 35(13.3%). Diffuse (29.2%) and middle and lower co-existing distribution (25.8%) whereas just lower lobe (13.3%) were the most common predominance in severity. Peripheral involvement was also seen in (8.7%) cases. Conclusion: Both lungs are equally affected with the disease having the consolidation and opacifications while the effusion is the major complication in the severe cases. Diffuse involvement of the lung lobes is seen in the study followed by the middle and lower lobe involvement.

5.
Pakistan Journal of Medical and Health Sciences ; 16(8):24-26, 2022.
Article in English | EMBASE | ID: covidwho-2067738

ABSTRACT

Aim: To evaluate the potential use of ivermectin with standard therapy among mild to moderate covid-19 illness. Methods: This is a single-centered, prospective observational, randomized, parallel group (1:1 ratio), standard versus controlled ivermectin study recruited 210 confirmed COVID-19 positive patients who were admitted in COVID treatment center of Dr Ruth Kum Pafu Civil hospital Karachi, Pakistan from 1st November 2020 to 30th May 2021. Data were analyzed using SPSS version Results: Total of 210 patients were enrolled in the study and aged matched patients were divided in two groups 105 patients received ivermectin 6 mg twice a day for five days along with standard therapy while remaining 105 patients received standard therapy as per local and international guidelines. Male were 140(66.7%) and female 70(33.3%);age ranges between 26 to 77 years and majority 140( 66.7%) were more than 50 years of age. Fever, dry cough and dyspnea were the major symptoms seen;112(53.3%) patients had DM as a comorbid illness . Total of 21(20%) of 105 patients of ivermectin group had negative PCR for COVID 19 on day seven while the other group had positive covid test in all of 105 patients . On day 10 total of 49 more patients from ivermectin group found COVID negative along with 21 previously negative had second PCR was found negative in this way total of 70( 66.7%) of ivermectin group had negative PCR for COVID 19 while 21(20%) patients from non ivermectin got negative PCR for COVID 19 on day 10 . Conclusion: Use of ivermectin with standard therapy clear the virus earlier than standard therapy in mild to moderate COVID-19 infected patients admitted in COVID treatment center of Dr Ruth Kum Pafu Civil Hospital Karachi.

6.
Research Journal of Pharmacy and Technology ; 15(8):3717-3724, 2022.
Article in English | EMBASE | ID: covidwho-2067732

ABSTRACT

Background: Health care workers (HCWs), being in the front line dealing with COVID-19 patients, are facing various challenges. Therefore, being aware about COVID-19 is of high importance. The overall aim of this study is to evaluate the HCWs' knowledge and attitude about COVID-19. The objectives of the study are assessment of HCWs' knowledge and attitude about COVID-19 and determining the significant factors that influence their knowledge. Methods and Materials: a descriptive cross-sectional study was carried out among convenient sample (n=353) of HCWs in the UAE by using an online self-administrated questionnaire. The data was analyzed using the SPSS version 26. Mann Whitney u test and Kruskal Wallis test were used to test the differences in quantitative variables across groups. Multivariate logistic regression analysis was used to investigate the association between the knowledge about COVID-19 and significant factors. A p value <0.05 was chosen as the criteria to make decisions regarding statistical significance. Result(s): A total of (353) HCWs participated in the study and completed the whole questionnaire. The average knowledge score was 76.3% with a 95% confidence interval (CI) [75.2%, 77.5%]. Of the total participants, 122 (34.6%) have poor knowledge, 81 (22.9%) have acceptable knowledge and 150(42.5%) have good knowledge. In the present study, significantly higher knowledge scores were observed in Western participants (OR 2.83;95% CI 1.51 - 5.29), General practitioners (OR 1.319;95% CI 1.03 - 1.69), participants working in Dubai (OR 1.47;95 % CI 1.28- 1.69) and participants who had been in contact with suspected or confirmed COVID-19 cases (OR 1.235;95% CI 1.11- 1.37). On the other hand, significantly lower knowledge scores were observed in participants aged 30-39 years (OR 0.760;95% CI 0.647- 0.893), Arabian participants (OR 0.76;95 % CI 0.58- 0.98) and participants with less than 1year experience (OR 0.729;95% CI 0.601- 0.883). Conclusion(s): This study revealed that HCWs working in the UAE have a good level of general knowledge about COVID-19 symptoms, transmission, progression, and prevention. Questions about deeper knowledge revealed a lower level of knowledge. Therefore, tailored awareness campaigns may be required in order to meet HCWs' needs and enhance their levels of deep knowledge. Copyright © RJPT All right reserved.

7.
Indian Journal of Forensic Medicine and Toxicology ; 16(3):63-68, 2022.
Article in English | EMBASE | ID: covidwho-2067687

ABSTRACT

Background: COVID-19 is a pandemic disease caused by droplet infection from SARS-CoV-2. Due to its rapid transmission and high case fatality rate, the identification of risk factors and prognostic factors is important. Obesity is a risk factor for poor outcomes in COVID-19. It is associated with chronic inflammation, disorders of the immune system. Obesity can be determined based on BMI. Chest X-Ray is supported in establishing the diagnosis and prognosis of COVID-19 patients. Assessment of the severity index of Chest X-Ray radiographs can use the Modified Chest X-Ray Scoring System of RSUP Dr. Soetomo. This study was conducted to analyze the relationship between BMI and chest radiography severity index in hospitalized COVID-19 patients at dr. Mohammad Hoesin Palembang in 2021. Methods: This research used a cross-sectional analytic observational design. Sampling was done using a consecutive sampling technique with 70 samples and obtained from the patient's medical record. The data were analyzed by univariate and bivariate (Chi-Square) using IBM SPSS Statistics 26 software. Results: Patients with BMI Overweight-Obesity had more in Moderate-Severe (18.6%) radiographic severity index scores (18.6%) than Normal-Mild (15.7%). Chi-Square bivariate analysis, BMI (p=0.033;p-value <0.05) had a significant relationship with the chest radiographic severity index with Odds Ratio 3,00, 95% CI (1,073–8,386). Conclusion: There is a significant relationship between body mass index and chest radiography severity index in COVID-19 patients. Overweight-Obesity BMI patients have a 3-fold chance of having a Moderate-Severe category of radiographic severity index compared to Underweight-Normal BMI patients.

8.
Aging Medicine and Healthcare ; 13(3):132-138, 2022.
Article in English | EMBASE | ID: covidwho-2067646

ABSTRACT

Background/Purpose: Due to the pandemic of COVID-19 and the need to pay attention to the older adults as one of the most vulnerable groups, this study aimed to determine the effects of educational programs based on the Protection Motivation Theory (PMT) as non-pharmaceutical intervention in promoting protective behaviors against COVID-19 among the older adults in Hamadan. Method(s): The present study was a randomized controlled trial performed in 2021 on 80 older adults visiting retirement centers in Hamadan. Participants were randomly assigned to experimental (n=40) and control groups (n=40). The data collection tool was a researcher-made questionnaire including demographic variables and constructs of PMT which were completed before and two months after the intervention. The intervention consisted of four sessions implemented for the experimental group. The collected data was analyzed in SPSS-16 using Chi-square, Mann-Whitney, and Wilcoxon tests. Result(s): There was no significant difference between the two groups in terms of all demographic variables and theoretical constructs before the educational intervention. After the educational intervention, there was a significant difference in the constructs of perceived severity (P=0.012), perceived response efficiency (P=0.009), perceived self-efficacy (P=0.021), and perceived response cost (P <0.001) after the intervention. No significant changes were reported in the control group (P >0.05). Also, results showed that there was no significant difference in the mean of COVID-19 preventive behaviors between the two groups after the educational intervention (P >0.05). Conclusion(s): The results showed that the use of educational intervention as non-pharmaceutical intervention based on the PMT was an effective approach to perform preventive behaviors against infectious diseases such as COVID-19. Copyright © 2022, Full Universe Integrated Marketing Limited. All rights reserved.

9.
NeuroQuantology ; 20(11):1858-1865, 2022.
Article in English | EMBASE | ID: covidwho-2067333

ABSTRACT

Background: Fighting the Covid-19 pandemic is one of the global priorities now, and the most important type of pandemic control is vaccination. Pfizer-Biotech is considered one of the most important vaccines currently because of its high effectiveness in stimulating the immune system, despite limited data regarding the duration of the response and its side effects. The goal of this study is to assess the response ofSARS CoV-2 S1-RBD IgG andInterleukin-15 after 30 and 120days fromthe 2nd dose ofPfizer-BioNTech vaccine which applied on themedical college students at Diyala university. Methodology: This study began after the obtainment of the Medical College of the University of Diyala, the Medical College of Al-IraqiaUniversity, and the Iraqi Ministry of Health approvals . It continued from October 2021 until March 2022.A total of45 male and femaleparticipants from the College of Medicine( DiyalaUniversity)students who took thetwo doses of Pfizer-BioNTech and were divided into two groups: 1 month (30 days) and 4 months (120 days) after the full vaccination (two doses).A 5 ml of their blood was taken two times (30 days and 120 days after the 2nd dose of thePfizer-BioNTech vaccine) in the postgraduate laboratories inside the Diyala Medical College. A serological analysis to quantify IL-15 and SARS CoV-2 S1-RBD IgG has been done using BT LAB/ Bioassay Technology Laboratory/ Human Interleukin 15 ELISA Kit from CHINA andDiasino/ SARS CoV-2 S1-RBD IgG ELISA Kit/ CHINA respectively. All the lab work happened in the postgraduate laboratories inside the Diyala Medical College. Demographic information (Age and Gender) has been collected from the participants. These participants were split into two groups depending on the time after the 2nd of Pfizer-BioNTech vaccine dose (1 month and 4 months, respectively). STATISTICA (version 12 )and SPSS (version 26 ) were used to input, review and data analysis. Essential approaches of percentages and frequencies were used for qualitative variables, while, average and standard deviation were used for quantitative variables. For both IL-15 and SARS CoV-2 S1-RBD IgG, less than 0.05 of a P-value was considered considerable. Result(s): The ratio, according to gender, was (17.8: 82.2) while the age Average was (20.9 years old). The serum data of IL-15 and SARS-CoV-2 S1-RBD IgG levels after 1 month (30 days) and 4 months (120 days) were statistically non-parametric. Mann-Whitney test (Independent two samples), showeda considerabledrop(P<0.05) of IL-15as well as SARS CoV-2 S1-RBD IgGserum levels in the 4th-monthsgroup compared to the 1-monthgroup. Conclusion(s): Interleukin-15 and SARS CoV-2 S1-RBD IgG serum levels significantly droped after 120days of the 2nd dose of Pfizer-BioNTech vaccine. Copyright © 2022, Anka Publishers. All rights reserved.

10.
NeuroQuantology ; 20(9):4491-4503, 2022.
Article in English | EMBASE | ID: covidwho-2067293

ABSTRACT

Over the last decade, India has witnessed an exponential rise in the sales through e-commerce platforms. With the pandemic-related lockdowns and social distancing norms being the new normal, individuals are forced to shop online, for their day-to-day requirements. The trend has become increasingly pronounced in the last year. One such domain that has come to the fore in our fight against the epidemic is e-Pharmacy. Increasing internet penetration, e-commerce adoption, and changing consumer preferences are some of the growth drivers of e-pharmacy and the market is expected to grow at a compounded rate of 44 per cent to reach $ 4.5B by 2025 in India. However, the sector also faces several challenges like lack of trust, privacy issues, legal concerns and limited geographical presence. In the context of the lack of studies examining consumer attitude towards e-pharmacy in India, this study investigates the effects of risk perception, perceived usefulness and subjective norms on customers’ online purchase intention towards e-pharmacy. The data is collected from 490 customers across different parts of India through online and offline data collection modes, out of which 423 was the final sample size, after deleted the incomplete questionnaires. Purposive sampling was employed to select the sample respondents, and data analysis have done using statistical tool IBM SPSS. The study revealed the significant relation between risk perception and perceived usefulness towards online purchase intention while the influence of subjective norms on online purchase intention is found insignificant. Online pharmacies have shown a lot of promise in terms of enhancing pharma retail. Their continued expansion would improve the digital healthcare ecosystem and help the government to achieve its goals of providing efficient and cheap health coverage. The insights gained from this study will significantly help health marketing professionals and other stakeholders to formulate their strategies more effectively.

11.
Journal of Clinical and Diagnostic Research ; 16(9):DC01-DC06, 2022.
Article in English | EMBASE | ID: covidwho-2067189

ABSTRACT

Introduction: Coronavirus Disease-2019 (COVID-19) vaccination plays an important role in controlling the current pandemic. This may have an impact on other healthcare workers in understanding the importance of COVID-19 vaccination. Aim: To assess the Knowledge, Attitude and Practice (KAP) towards COVID-19 vaccination among medical students in a Tertiary care hospital, Southern India. Materials and Methods: This was an observational cross-sectional questionnaire based study done in Mahatma Gandhi Medical College and Research Institute, Puducherry, India. The study period was from April 2021 to September 2021. The study evaluated KAP on COVID-19 vaccination amongst medical students. After the content validity of the questionnaire, a google form was created and circulated among the I, II, III, IV-year students and interns, which was assessed by a scoring system for KAP. The results of the qualitative variables were tabulated as frequency and percentages. The statistical analysis was done using JASP software and the correlation between KAP was calculated using Spearman's Correlation. Results: A total of 400 participants were included in the study. Their mean±SD age was 20.3±1.3 years. The second- and third-year students actively participated in the study. Adequate knowledge was observed in 33% of the medical students, moderately adequate knowledge in 61% and minimum knowledge in 6%. Spearman's correlation between KAP showed a significant p-value. Conclusion: The majority of the medical students opined that their main source of information was social media. This indicates that social media campaigns had helped them gain adequate knowledge about vaccination. This knowledge might help them encourage their relatives and friends to get vaccinated against COVID-19, which will in turn help in breaking the chain of this pandemic.

12.
National Journal of Physiology, Pharmacy and Pharmacology ; 12(10):1735-1740, 2022.
Article in English | ProQuest Central | ID: covidwho-2067047

ABSTRACT

There is a statistically significant positive correlation between number of patients attended per day and antibiotics prescribed. MATERIALS AND METHODS This cross-sectional, prospective, questionnaire-based study was conducted after ethics committee approval (BVDUMC/ IEC/40 dated July 06, 2020). [...]a Google Forms was prepared in English and circulated among general practitioners of all pathies who we knew personally and professionally on WhatsApp groups from where it was circulated further. Knowledge questions focused on handling of common conditions, commonly used drugs, antibiotic resistance, and knowledge about measures to prevent resistance like antimicrobial stewardship program (AMSP).

13.
Pharmacognosy Magazine ; 18(79):773-782, 2022.
Article in English | EMBASE | ID: covidwho-2066903

ABSTRACT

Background: Tabebuia impetiginosa is an important medicinal plant rich in lapachol, alpha-lapachone, and beta-lapachone known to possess several biological activities. Objective(s): In this study, we investigated the drug potential of lapachol, alpha-lapachone, and beta-lapachone using molecular docking, molecular dynamic (MD), and drug-likeness properties. Material(s) and Method(s): The computational study was performed using SwissADME software for the determination of the pharmacokinetic properties of the tested compounds. AutoDock Vina and Genetic Optimization for Ligand Docking (GOLD) were used for the docking analysis, and MD simulations were run using Schrodinger's Desmond Simulation. Result(s): The three compounds lapachol, alpha-lapachone, and beta-lapachone binds to cysteine (Cys)-histidine (His) catalytic dyad (Cys145 and His41) along with the other residues with, respectively, the following docking score 48.69, 47.06, and 47.79. Against viral entry receptor, human angiotensin-converting enzyme 2 (hACE-2), alpha-lapachone exhibited the highest GOLD Fitness score complex (54.82) followed by lapachol (42.53) and beta-lapachone and hACE-2 (38.74) generating several active sites in the target proteins. A 100 ns MDs simulation study revealed the stable conformation of bioactive compounds within the cavity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of hACE-2 protein and main protease (Mpro). From the dynamic study, it was observed that lapachol was tightly bound with catalytic dyad residue Cys145 of Mpro with more than 40% time of simulation, also post-simulation MM-GBSA binding free energy (DELTAG Bind) revealed the highest energy score (-51.18 +/- 5.14 kcal/mol) among the evaluated complex. Moreover, the absorption, distribution, metabolism, and excretion (ADME) properties demonstrated that the investigated compounds passed the pharmacokinetic and drug-likeness criteria without undesirable effects. Conclusion(s): The computational study highlighted that these compounds could be highly recommended and developed as part of an effective drug against the SARS-CoV-2 virus. Copyright © 2022 Pharmacognosy Magazine.

14.
Indian Journal of Occupational and Environmental Medicine ; 26(3):140-150, 2022.
Article in English | EMBASE | ID: covidwho-2066865

ABSTRACT

Background: The COVID-19 pandemic has necessitated the use of personal protective equipment (PPE) among the frontline health care workers (HCWs). Even though PPE helps in preventing infection, it poses significant physical and psychological impacts at varying levels. Correspondingly, multiple independent studies have brought out the PPE-associated problems. However, there exists a lacuna on comprehensive information of global prevalence related to the same. Aim(s): To estimate the prevalence and risk factors of PPE among HCWs during COVID-19 across the globe. Design(s): Systematic review and meta-analysis. Method(s): The review was undertaken as per the protocol registered in PROSPERO CRD42021272216 following Preferred Reporting Items for Systematic Reviews and Meta-Analysis(PRISMA) guidelines. Two independent reviewers have undertaken the search strategy, study selection, and methodological quality assessment. Discrepancies were addressed by the third reviewer. Heterogeneity was addressed through I2 statistics and forest plots generated by open meta-software. Result(s): A total of 16 articles conducted across 6 different countries among 10,182 HCWs were included in the review. The pooled prevalence of skin lesions, headache, sweating, breathing difficulty, vision difficulty, thirst/dry mouth, fatigue, and communication difficulty, anxiety, fear were 57 (47-66%), 51 (37-64%), 75 (56-90%), 44 (23-68%), 61 (21-94%), 54 (30-77%), 67 (58-76%), 74 (47-94%), 28 (24-33%), 14 (10-17%), respectively. Moreover, the various risk factors included are the use of PPE for >6 h and young females. In addition, the medical management of new-onset problems created an additional burden on the frontline health care personnel (HCP). Conclusion(s): The frontline HCWs encountered physical and psychological problems at varying levels as a result of wearing PPE which needs to be addressed to prevent the inadequate use of PPE leading to infections. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

15.
Journal of Acute Disease ; 11(4):120-126, 2022.
Article in English | EMBASE | ID: covidwho-2066823

ABSTRACT

Unbalanced magnesium levels in the body, like other minerals, are a factor that is important in the severity and mortality of COVID-19. This study was designed to investigate the relationship between serum magnesium levels and clinical outcomes in COVID-19 patients. In this systematic review, a comprehensive search was performed in PubMed, Scopus, and Web of Science databases until September 2021 by using the keywords COVID-19, severe acute respiratory syndrome coronavirus 2, coronavirus disease, SARS- COV-infection 2, SARS-COV-2, COVID 19, and magnesium. End-Note X7 software was used to manage the studies. Articles that evaluated effect of magnesium on COVID-19 were included in the analysis. After reviewing several articles,12 studies were finally included in the ultimate analysis. The studies show that hypomagnesemia and hypermagnesemia are both factors that increase mortality in patients with COVID-19, even in one study, hypomagnesemia is the cause of doubling thedeaths in COVID-19 patients. Some studies have also found a negative correlation between magnesium deficiency and infectionseverity, while some others have reported no correlation between magnesium level and disease severity. According to the important role of magnesium in the body and its involvement in many physiological reactions, as well as differences in physical and physiological conditions of COVID-19 patients, in addition to the need for studies with larger sample sizes, monitoring and maintaining normal serum magnesium levels during the disease seems necessary as a therapeutic target, especially in patients admitted to the intensive care unit.

16.
Open Access Macedonian Journal of Medical Sciences ; 10(E):1169-1173, 2022.
Article in English | EMBASE | ID: covidwho-2066702

ABSTRACT

BACKGROUND: The implementation of the vaccine on a large scale has almost reached all provinces in Indonesia. East Kalimantan, one of the provinces affected by COVID-19, has also implemented a vaccine program. Seroprevalence surveys are essential to describe the success of vaccine program based on antibody titer test. AIM: This study aims to determine the anti-SARS-CoV-2 antibody titer value based on the type of vaccine received by the academic community in Samarinda, one of the cities most affected by COVID-19 in East Kalimantan. METHODOLOGY: The study was population-based. The study sampled 100 people from the community. Participants must be in good health, aged 16–60, with a positive COVID-19 test, no comorbid illnesses or other chronic problems, no blood transfusions, and most importantly, have received the least initial dosage of immunization. The data will be analyzed using SPSS 26 and STATA 16. A normality test and Tobit regression test to determine the antibody distribution in each vaccine type. RESULTS: The results showed that Moderna COVID-19 Vaccine provided a significant (p = 0.001) increase in antibody prediction of 1090 U/ml (95% CI: 764–1416), while Pfizer provided a significant (p = 0.000) rise of 766 U/ ml (95% CI: 307–1226). CONCLUSION: According to the results of a seroprevalence survey conducted among the academic community in East Kalimantan, receivers of inactivated vaccinations outnumbered those of mRNA and vector-based vaccines. It can be determined that booster immunizations for students and academic staff are required to guard against COVID-19 infection. As boosters, both Moderna’s COVID-19 Vaccine and Pfizer’s COVID-19 Vaccine are strongly recommended.

17.
Open Access Macedonian Journal of Medical Sciences ; 10(A):1234-1241, 2022.
Article in English | EMBASE | ID: covidwho-2066698

ABSTRACT

BACKGROUND: The emergence of COVID-19 in the late of 2019 resulted in the massive screening of drugs, including natural products, to support the current vaccines. Apium and Foeniculum vegetables are members of the Apiaceae family that potentially used to be natural immunosuppressant. AIM: The purpose of this research is to analyze the phylogenetic position between these two plants as well as find out their secondary metabolites potency against COVID-19 main protease (Mpro) and the papain-like protease (PLpro). METHODS: The phylogenetic analysis of Apium and Foeniculum from Indonesia was carried out based on internal transcribed spacer (ITS) region and the bioactive virtual screening assay was completed through AutoDock Vina software. CONCLUSION: Overall, Apium and Foeniculum have close relationships among the members of Apiaceae after maximum likelihood analysis. Furthermore, it also has 70 similar bioactive compounds that some of these potentially inhibit both of COVID-19 proteases.

18.
Sustainability ; 14(19):12879, 2022.
Article in English | ProQuest Central | ID: covidwho-2066476

ABSTRACT

Environmental, Social, and Governance (ESG) criteria are novel and exciting tools of corporate disclosure for decision making. Using quantitative and qualitative analyses, the present study examined the key characteristics and trends of ESG controversies in the European market. At the same time, it identified the controversies’ determinants. A bibliometric analysis was the qualitative method employed on the data derived from Scopus using Biblioshiny software, an R package. The quantitative analysis involved an international sample of 2278 companies headquartered in Europe from 2017–2019 being studied using a Generalized Linear Model. The findings of this research highlighted the role of the “S” and the “G” dimensions of the ESG controversies as the most crucial in affecting controversies. Women are under-represented in the business hierarchy, but their natural characteristics such as friendliness and peaceability lead to a low level of illegal business practices. However, independent of gender, executives have personal gains that they want to satisfy. Thus, executives may become involved in unethical practices and harm their colleagues and the business’s reputation. On the other hand, democracy emerged as one of the most disputed factors. Democracy gives people the voice to express themselves and publicly support their ideas without restrictions. Although, the regression results showed that democracy is not always operated as the “pipe of peace” and can affect, to some extent, controversies.

19.
Energies ; 15(19):7374, 2022.
Article in English | ProQuest Central | ID: covidwho-2065784

ABSTRACT

With rising electricity demand, heavy reliance on imports, and recent economic downturns due to the negative impact of the COVID-19 pandemic, supply chain bottlenecks, and the Russian invasion of Ukraine, Thailand is suffering severely from energy resilience risks. The government has therefore set a goal of decentralizing energy production through small-scale distributed renewable energy systems. To support their design and the planning process, we simulate multiple scenarios with wind turbines, photovoltaic systems, and battery storage for a model community in rural Nakhon Phanom, Thailand. Using the software NESSI4D, we evaluate and discuss their impact on energy resilience by considering environmental sustainability, economic attractiveness, and independence from the central power grid. To fill the gap of missing data on energy demand, we synthesize high-resolution load profiles from the Thailand Vietnam Socio-Economic Panel. We conclude that distributed photovoltaic systems with additional battery storage are only suitable to promote energy resilience if the government provides appropriate financial incentives. Considering temporal variations and local conditions, as well as a participatory decision-making process, are crucial for the long-term success of energy projects. Our advice to decision-makers is to design policies and regulatory support that are aligned with the preferences and needs of target communities.

20.
Frontiers in Education ; 7, 2022.
Article in English | Scopus | ID: covidwho-2065495

ABSTRACT

The research aimed to investigate the impact of introducing language learning software to university students in the learning environment influenced by COVID-19. It describes the results of an experience with adding daily activities in Elevate, a free language learning application marketed as brain training software for the undergraduate English curriculum. The experiment took place at RUDN University (Moscow, Russia) in 2021 during the COVID-19 pandemic. Participants were engaged in synchronous distance and face-to-face learning, depending on their location and the current epidemiological situation. Some students alternated between online and offline environments. Research methods included a theoretical analysis of current trends in language training and gamification. Statistical data were collected and processed using the university’s digital ecosystem. The research included quantitative data from the experiment and surveys, which consisted of multiple-choice, single-choice, and open-ended questions. The research sample included students from eight countries with the common european framework of reference for languages (CEFR) levels of English from B1 to C1. The research results show the effects of language learning software on students’ language proficiency (P). From the results of this research, it can be concluded that schools and universities can use multi-level feedback from participants to maximize the effectiveness of language training and diversify the range of activities included in the curriculum. The results also provide the theoretical basis for e-learning software development and represent a new contribution to the literature. Copyright © 2022 Novikov.

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