Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 4.153
Filter
1.
Journal of ISAKOS ; JOUR:551, 6(6).
Article in English | EMBASE | ID: covidwho-2088867

ABSTRACT

We highlight the benefits of a formal preseason in professional football in terms of there being a lower injury rate at the start of the season following a formal preseason. Data Background The 'preseason' is an established period of the professional football season for players to gain fitness and has been demonstrated to subsequently improve player performance following the start of the season. Although players are at greater risk of injury in the preseason period, it is questioned whether a preseason subsequently decreases the risk of injury in the start of the formal season itself. Due to the established nature of the preseason no studies have previously reviewed the effect of the preseason on injury rates in the subsequent season. Our aim was to report the injury rate from post-lockdown professional football games (no preseason programme -NPP) and compare to the start of the season (following a preseason programme -FPP). This would then provide a comparison between the two groups and a determination of the potential beneficial effect of a formal preseason on the injury rates at the start of the formal season. Methods We compared the injuries sustained across 4 European Professional Football Leagues (Premier League, Serie A, Bundesliga, La Liga) from the first 2 games for each team at the start of the 2019-20 season (FPP group) and from the first 2 games for each team after the re-start of football following lockdown (NPP group). We recorded the frequency, injuries per game, contact and soft tissue injuries. An injury was recorded if the player was deemed unable to continue play. Results In total 156 games were reviewed, 78 in the FPP group and 78 in the NPP group. A total of 10 injuries were observed in the FPP group games, 0.13 per game, compared to 30 injuries in the NPP group games, 0.39 per game (p=0.001). The ratio of contact to soft tissue injuries was the same for both groups (1:4). There was no significant difference in the length of downtime between the leagues stopping and restarting (92-103 days) and no correlation between injury rate and length of downtime. Conclusions Injuries in elite professional football were more common in the first 2 games following the restart after lockdown than in the first 2 games of the 2019/20 season. We believe this is due to the beneficial effect of a normal preseason being absent for the restart. We highlight the importance of preseason in reducing injury rates amongst professional footballers.

2.
Embase; 23.
Preprint in English | EMBASE | ID: ppcovidwho-346780

ABSTRACT

Antibody-deficient patients respond poorly to COVID-19 vaccination and are at risk of severe or prolonged infection. Prophylaxis with anti-SARS-CoV-2 monoclonal antibodies has been considered. We here demonstrate that many immunoglobulin preparations now contain neutralising anti-SARS-CoV-2 antibodies which are transmitted to patients in good concentrations, albeit with significant differences between products. Copyright The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

3.
Embase; 27.
Preprint in English | EMBASE | ID: ppcovidwho-346615

ABSTRACT

Background: COVID-19 pandemic affected common disease infections, while the impact on hand, foot, and mouth disease (HFMD) is unclear. Google Trends data is beneficial in approximately real-time statistics and easily accessed, expecting to be used for infection explanation from information-seeking behavior perspectives. We aimed to explain HFMD cases before and during COVID-19 using Google Trends data. Method(s): HFMD cases were obtained from the National Institute of Infectious Disease, and Google search data from 2009 to 2021 was downloaded using Google Trends in Japan. Pearson correlation coefficients were calculated between HFMD cases and the search topic "HFMD" from 2009 to 2021. Japanese tweets containing "HFMD" were retrieved to select search terms for further analysis. Search terms were retained with counts larger than 1000 and belonging to ranges of infection sources, susceptible sites, susceptible populations, symptoms, treatment, preventive measures, and identified diseases. Cross-correlation analyses were conducted to detect lag changes between HFMD cases and HFMD search terms before and during COVID-19. Multiple linear regressions with backward elimination processing were used to identify the most significant terms for HFMD explanation. Result(s): HFMD cases and Google search volume peaked around July in most years without 2020 and 2021. The search topic "HFMD" presented strong correlations with HFMD cases except in 2020 when COVID-19 outbroke. In addition, differences in lags for 73 (72.3%) search terms were negative, might indicating increasing public awareness of HFMD infections during the COVID-19 pandemic. Results of multiple linear regression demonstrated that significant search terms contained the same meanings but expanded informative search content during COVID-19. Conclusion(s): Significant terms for HFMD cases explanation before and during COVID-19 were different. The awareness of HFMD infection in Japan may improve during the COVID-19 pandemic. Continuous monitoring is important to promote public health and prevent resurgence. Public interest reflected in information-seeking behavior can be helpful for public health surveillance. Copyright The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

4.
Embase; 23.
Preprint in English | EMBASE | ID: ppcovidwho-346595

ABSTRACT

The first step in SARS-CoV-2 genomic surveillance is testing to identify infected people. However, global testing rates are falling as we emerge from the acute health emergency and remain low in many low- and middle-income countries (LMICs) (mean = 27 tests/100,000 people/day). We simulated COVID-19 epidemics in a prototypical LMIC to investigate how testing rates, sampling strategies, and sequencing proportions jointly impact surveillance outcomes and showed that low testing rates and spatiotemporal biases delay time-to-detection of new variants by weeks-to-months and can lead to unreliable estimates of variant prevalence even when the proportion of samples sequenced is increased. Accordingly, investments in wider access to diagnostics to support testing rates of ~100 tests/100,000 people/day could enable more timely detection of new variants and reliable estimates of variant prevalence. The performance of global SARS-CoV-2 genomic surveillance programs is fundamentally limited by access to diagnostic testing. Copyright The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

5.
Embase; 24.
Preprint in English | EMBASE | ID: ppcovidwho-346564

ABSTRACT

Introduction Some reports have suggested that as many as one-half of all hospital inpatients identified as COVID-19-positive during the Omicron BA.1 variant-driven wave were incidental cases admitted primarily for reasons other than their viral infections. To date, however, there are no prospective longitudinal studies of a representative panel of hospitals based on pre-established criteria for determining whether a patient was in fact admitted as a result of the disease. Materials and Methods To fill this gap, we developed a formula to estimate the fraction of incidental COVID-19 hospitalizations that relies upon measurable, population-based parameters. We applied our approach to a longitudinal panel of 164 counties throughout the United States, covering a 4-week interval ending in the first week of January 2022. Results Within this panel, we estimated that COVID-19 incidence was rising exponentially at a rate of 9.34% per day (95% CI, 8.93-9.87). Assuming that only one-quarter of all Omicron BA.1 infections had been reported by public authorities, we further estimated the aggregate prevalence of active SARS-CoV-2 infection during the first week of January to be 4.89%. During the same week, among 250 high-COVID-volume hospitals within our 164-county panel, an estimated 1 in 4 inpatients was COVID-positive. Based upon these estimates, we computed that 15.2% of such COVID-19-positive hospitalized patients were incidental infections. Across individual counties, the median fraction of incidental COVID-19 hospitalizations was 13.7%, with an interquartile range of 9.5 to 18.4%. Conclusion Incidental COVID-19 infections appear to have been a nontrivial fraction of all COVID-19positive hospitalized patients during the Omicron BA.1 wave. In the aggregate, however, the burden of patients admitted for complications of their viral infections was far greater. Copyright The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

6.
Archives of Clinical Infectious Diseases ; 17(3), 2022.
Article in English | EMBASE | ID: covidwho-2067096

ABSTRACT

SARS-CoV-2, the pathogen responsible for COVID-19, has infected hundreds of millions since its emergence in late December 2019. Recently, concern has been raised due to the increased prevalence of co-infections with opportunistic pathogens among these pa-tients. Though not common, co-infections may be associated with adverse outcomes and increased risk of morbidity and mortality among patients suffering from COVID-19. Cytomegalovirus (CMV) infection is a serious problem among immunocompromised and critically ill patients. So far, few cases of co-infection with COVID-19 and CMV have been reported. Here, we report the co-infection with COVID-19 and CMV in a young woman presenting with sudden, progressive fever, delusion, agitation, bizarre behavior, seizure, and loss of consciousness leading to death despite receiving appropriate anti-viral treatment. To the best of our knowledge, this is the first case of coexisting SARS-CoV-2 and CMV infection presenting with severe, progressive meningoencephalitis in the era of COVID-19.

7.
Acta Haematologica Polonica ; 53(4):273-276, 2022.
Article in English | EMBASE | ID: covidwho-2067065

ABSTRACT

Introduction: As more data is collected, hematologists will be able to gain more insight into the impact of coronavirus disease 2019 (COVID-19) on pediatric patients with hematological malignancies. Material(s) and Method(s): We analysed 21 cases of COVID-19 in pediatric patients with onco-hematological diseases treated in the Western Ukrainian Pediatric Medical Center from March 2020 through May 2021. The majority of patients (71.4%) were diagnosed with acute lymphoblastic leukemia. All patients from the analyzed cohort had an asymptomatic, mild or moderate course of coronavirus-19 infection. The most common symptoms of COVID-19 were fever, cough, gastrointestinal symptoms, and dermatitis. Severe severe acute respiratory syndrome coronavirus 2 increased the risk of liver toxicity and venous thrombosis. Result(s) and Conclusion(s): Our analysis showed that pediatric patients with hematological malignancies need the same treatment approach for COVID-19 as for other infective complications. Copyright © 2022.

8.
Flora ; 27(2):276-285, 2022.
Article in English | EMBASE | ID: covidwho-2067059

ABSTRACT

Introduction: Vaccination plays an important role in all strategic actions against the COVID-19 pandemic. Despite the high safety and efficacy of vaccination, side effects of the vaccines may also occur. The purpose of this study was to evaluate the clinical and sonographic findings and short-term results of cervical and axillary lymphadenopathy after the BNT-162b2 mRNA vaccine. Materials and Methods: The patients who received at least one dose of BNT-162b2 mRNA vaccine between July-September 2021 and were detected to have ipsilateral axillary and cervical lymphadenopathy related closely to the vaccination period, were included in the study. Clinical characteristics, sonographic findings of lymphadenopathies, and short-term results were analyzed retrospectively. Results: A total of 13 patients [six females (46.2%), seven males (53.8%)] were evaluated in the present study. Mean age of the patients was 41.9 years (min-max= 20-56). Median time-lapse between vaccination and presentation to hospital was six days, and seven (53.8%) patients presented with symptoms and findings after the first dose, and six patients (46.2%) after the second dose. Three (23.1%) axillary lymphadenopathies, and 10 (76.9%) cervical lymphadenopathies were detected. Sonographic examination revealed lymphadenopathies predominantly oval morphology (69.2%), asymmetric cortical thickening (61.5%), and hilar-type vascularization (69.2%). Mean time of regression was found 19.2 days (min-max= 10-35). Conclusion: Ipsilateral cervical and axillary lymphadenopathies may occur because of vaccines against COVID-19. The sonographic findings of these lymphadenopathies may not be distinguished clearly from malignant lymph nodes;and for this reason, close clinical and radiological follow-up would be appropriate to elucidate the process.

9.
Pravention und Rehabilitation ; 34(3):81-99, 2022.
Article in German | EMBASE | ID: covidwho-2067043

ABSTRACT

Background: The SARS-CoV-2 pandemic is a global crisis with massive effects on all areas of society, such as the labor market, social security systems, and healthcare. It represents a complex stress situation that hardly leaves anyone unscathed. As a result, a significant increase in mental stress and ill- ness has been observed since the beginning of the pandemic. The coronavirus pandemic almost paralyzed rehabilitation in the spring of 2020. When comparing the 1st quarter of 2019 with that of 2021 (cumulative), a decrease of –32.8% is recorded for 2021 in the applications for services for medical rehabilitation (total 2020 to 2019: –14.2%). For the rehabilitation centers, the central and vital question is under which conditions rehabilitation measures can be carried out safely and successfully even in times of a pandemic. This also includes the confi-dence of potential rehabilitation patients, referring physicians, and employees in the structural and procedural measures taken by the centers. Materials and methods: The study aims to shed light on the effects and coping attempts of the pandemic in medical rehabilitation from different perspectives and to provide indications for routine care in “COVID normal operation”. The focus is on a comparative analysis of the results of the routine survey in the period October 2019 to June 2020, interviews with the management level of the center as well as a cat-amnestic follow-up survey of rehabilitation patients who completed a psychosomatic rehabilitation measure in the center in the period January to September 2020. Results: The interviews at the management level and the analysis of the safety concept show that a crisis team was installed at a very early stage in the center and a safety concept was established, which met with a high level of acceptance among all participants and contributed to a feeling of safety. The comparison of the routine survey shows that, with the exception of individual cases, the rehabilitation measures were carried out and completed according to plan. In most areas, the ratings have even improved in the 1st half of 2020 compared to the 4th quarter of 2019. The results of the catamnestic survey confirm the results of the routine survey. The rehabilitation patients who were treat-ed at the Rehazentrum Bad Bocklet during the COVID pandemic showed pronounced psychosomatic and participation-related limitations in the period before or at admis-sion. Regarding concerns and fears about the COVID situation, almost half of all respondents stated strong or very strong fears about the effects of the COVID pandemic on personal or close persons. In the foreground are fears that a close person could become infected or die. The hospital’s safety measures in terms of hygiene and adapted struc-tures and processes were rated positively by around three quarters of respondents. This is also confirmed by the results of the outcome parameters examined. The personal therapy goals were achieved for about three quarters of the respondents. Positive chang-es were seen in terms of health, health com-plaints, anxiety and depression symptoms, global health and the development of the ability to work, among other things. The RTW rates are 71% (time point method) and 81% (cumulative time course). The benefit of the rehabilitation measure is rated as high by 73% of the respondents is the treatment satisfaction. Substantial influences of rehab motivation, admission periods, and percep-tion and evaluation of COVID measures at the center on key outcome parameters are shown. These results emphasize the role of appropriate safety and hygiene measures adapted to the current hazard situation in the context of rehabilitation measures. The results indicate that the hospital succeeded in implementing suitable measures right at the beginning of the pandemic, and in com-municating and living these measures ac-cordingly. In addition, they allow the conclu-sion that under suitable safety and hygiene conditions, rehabilitation measures can also be carried out safely in times of pandem c and still show stable effects in essential tar-get criteria of medical rehabilitation after one year.

10.
Intensiv- und Notfallbehandlung ; 47(3):156-161, 2022.
Article in German | EMBASE | ID: covidwho-2067042

ABSTRACT

Background: Lung ultrasound is an im-portant tool for distinguishing between causes and therapies of cardiorespiratory diseases in emergency departments (ED). Aim and method: Based on a case report, the importance of point-of-care ultrasound (POCUS) in the context of emergency di-agnostics and intensive care therapy will be illustrated. Case report: A 78-year-old male presented to the ED with dyspnea und weakness. A double mRNA-Covid vaccination was completed 3 months before. His medical history revealed multiple myeloma. Using POCUS, a severe Covid-19 pneumonia could be suspected, and at the same time other differential diagnoses were ruled out. PCR confirmed a SARS-CoV-2 infection. The patient was admitted to our intensive care unit with severe Covid-19 pneumonia fol-lowed by a complicated and ultimately le-thal course. Conclusion(s): In immunocompro-mised patients, there is still a high risk of a severe and complex course despite vaccina-tion. POCUS allows evaluation of probable Covid-19 pneumonia and rapid exclusion of possible differential diagnoses. Copyright © 2022 Dustri-Verlag Dr. K. Feistle.

11.
Romanian Journal of Legal Medicine ; 30(1):60-65, 2022.
Article in English | EMBASE | ID: covidwho-2066936

ABSTRACT

Introduction. During a pandemic, doctors are or are not willing to work due to numerous factors. Studies have shown that doctors tend to prioritize their own safety and the safety of their families. Objective. We have built a profile for doctors who prioritize their own safety and the safety of their families during a pandemic. Method. A total of 1285 Romanian doctors completed an online survey belonging to a larger study. We used a logistical binary regression to build a profile for doctors who consider their own safety and the safety of their families as having priority. All the participants responded, among other things, to an item about responsibility. We performed Backward-Wald computations to determine the best predictors. Results. We reached seven predictors that could differentiate between respondents who tended to agree with the responsibility statement and those who tended to disagree. The Cox and Snell pseudo R2 coefficient were.11. The predictors referred to: leaving the job to protect family, transportation, new job responsibilities, necessity of wage, needing to contribute, abandoning patients and working in a different hospital. Conclusion. The results show that doctors are not necessarily aligned with the theoretical “duty to care”. Those who prioritize safety for themselves and for their families seem to feel strongly about a hierarchy of values they have. For these doctors, institutional responsibility might take precedence with respect to patients, so they do not feel a sense of abandoning their patients if they don’t show up to work.

12.
Haseki Tip Bulteni ; 60(4):318-324, 2022.
Article in English | EMBASE | ID: covidwho-2066931

ABSTRACT

Aim: We think that the nasopharyngeal swab sample should be taken bilaterally to improve the sensitivity of the real-time-reverse transcriptase-polymerase chain reaction (RT-PCR) test since there may be pathologies that cause nasal obstruction, such as nasal septum deviation (NSD). In this context, we investigated the effect of the nasopharyngeal swab sampling method and the presence of nasal obstruction on the detection of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Method(s): This prospective clinical study was conducted from March 2021 to January 2022. Forty-four hospitalized patients with NSD were included in the study group, and 44 hospitalized patients without NSD were included in the control group. The results of the RT-PCR test studied with a unilateral nasopharyngeal swab sample taken during hospitalization and the RT-PCR test studied with a bilateral nasopharyngeal swab sample taken on the 2nd day of hospitalization and the visual analog scale (VAS) scores showing the patients' pain during the first sampling were determined. Result(s): In the first test, 23 (52.3%) patients in the study group and 32 (72.7%) patients in the control group were evaluated as SARS-CoV-2 positive. The first test sensitivity was significantly higher in the control group (p=0.048). The VAS score was significantly higher in the study group (p=0.00008). In the second test, 35 (79.5%) patients in the study group and 37 (84.1%) patients in the control group were evaluated as SARS-CoV-2 positive. The sensitivity increases in the study group and in the population were statistically significant (p=0.007 and p=0.004, respectively). The consistency of the first and second test results increased in patients without NSD and in patients with low VAS scores [odds ratio (OR)=3.779;p=0.001, OR=2.572;p=0.005, respectively]. Conclusion(s): Nasopharyngeal swab sampling may be affected by nasal congestion and the sampling method. To avoid this, it may be more appropriate to take a nasopharyngeal swab sample through the bilateral nasal cavity. Copyright © 2022 by The Medical Bulletin of Istanbul Haseki Training and Research Hospital The Medical Bulletin of Haseki published by Galenos Yayinevi.

13.
Journal of Applied Hematology ; 13(3):154-156, 2022.
Article in English | EMBASE | ID: covidwho-2066899

ABSTRACT

Cold agglutinin disease (CAD) is a distinct type of acquired immune hemolytic anemia. It can be idiopathic (primary) or secondary to infections, neoplasms and autoimmune diseases. Mycoplasma pneumonia and EBV are the infections commonly associated with secondary CAD. In the current COVID-19 pandemic, there are very few case reports showing an association between CAD and COVID-19.

14.
Indian Journal of Otology ; 28(2):186-188, 2022.
Article in English | EMBASE | ID: covidwho-2066876

ABSTRACT

Coronavirus disease-2019 (COVID-19) is an ongoing global pandemic exerting considerable strain on the health-care system. Sudden-onset sensorineural hearing loss (SSNHL) among patients with COVID-19 had been reported sparingly in the literature. Hearing loss can be easily overlooked in intensive care settings and establishing diagnosis can also be challenging. Proposed causes include injury to inner ear structures, cochlear nerve, or auditory brainstem. Prompt diagnosis and treatment is recommended to avoid long-term morbidity. All patients presenting with sudden-onset hearing loss should be screened for COVID-19. Here, we report a case of COVID-19 patient with SSNHL and how the hearing level is determined. Copyright © 2022 Indian Journal of Otology Published by Wolters Kluwer-Medknow.

15.
Indian Journal of Transplantation ; 16(2):237-238, 2022.
Article in English | EMBASE | ID: covidwho-2066874
16.
Journal of Acute Disease ; 11(4):161-164, 2022.
Article in English | EMBASE | ID: covidwho-2066827

ABSTRACT

Rationale: The impact of COVID-19 in patients with autoimmune liver disease treated with immunosuppressive therapy has not been described so far. This case report describes the clinical course of a patient with autoimmune hepatitis (AIH) who developed COVID-19 and the features of cytokine syndrome leading to its deterioration in our intensive care unit. Patient's Concern: A 28-year-old male presented with generalized anasarca for two weeks and chronic liver disease for 8 months. Diagnosis: AIH and Covid-19 with features of cytokine storm syndrome. Interventions: Intravenous furosemide, mannitol, syrup lactulose, steroids (prednisolone 40 mg), azathioprine 1 mg/kg body weight, rifaximin, vitamin K, and blood products. Outcomes: The patient had hepatic encephalopathy and AIH and died on the 10th day after admission despite ventilatory support, sustained low-efficiency hemodialysis, and resuscition. Lessons: The dramatic release of cytokines and the inflammatory-immune responses not only alter the pathophysiology but also affects the onset and severity of disease progression in patients with AIH.

17.
Chest Disease Reports ; 9(1) (no pagination), 2022.
Article in English | EMBASE | ID: covidwho-2066765

ABSTRACT

We present a case series of patients with pulmonary embolism of unknown etiology who did not have any risk factors. According to the findings, the most likely cause of the pulmonary embolism was undiagnosed, asymptomatic, or mild Corona Virus disease-2019 (COVID-19) infections in the recent past. In the current post-pandemic era, where there has been a surge of sudden unexplained deaths and pulmonary embolism cases, this case series emphasizes the importance of pulmonary embolism evaluation in patients seeking medical care for dyspnea. Physicians should be aware of the possibility of pulmonary embolism as a late complication in patients with mild, asymptomatic, or undiagnosed COVID-19 infection. Copyright © the Author(s), 2022.

18.
Open Access Macedonian Journal of Medical Sciences ; 10:1946-1949, 2022.
Article in English | EMBASE | ID: covidwho-2066707

ABSTRACT

Physiological changes during pregnancy and COVID-19 may affect one another. This report presents a 37-year-old female G4P10021 with gestational age 37+2 weeks infected with COVID-19 in Dr. Moewardi Hospital Surakarta, Central Java, Indonesia. The patient was diagnosed with antepartum hemorrhage due to total placenta previa with low-risk Morbidly Adherent Placenta score, a history of cesarean section, and ovarian cyst. The patient underwent conversion from spinal anesthesia to general anesthesia. Within 40 min after spinal anesthesia, the patient complained shortness of breath, which then worsened into decreased consciousness and inadequate spontaneous breathing. This may be complicated by the COVID-19 infection which has several effects on pregnancy.

19.
Open Access Macedonian Journal of Medical Sciences ; 10:1832-1834, 2022.
Article in English | EMBASE | ID: covidwho-2066701

ABSTRACT

BACKGROUND: During our past 18 months, we must be faced with the current COVID-19 pandemic era with much uncertainty in the continuation of multimodality treatment of the gastrointestinal cancer patients. Especially in this immunocompromised group with the history of previous chemotherapy treatment, these patients have an increased risk of COVID-19 transmission. Many studies have been reported about the current recommendation for gastrointestinal cancer patients during this pandemic, but there might be a lack of evidence about the safety of vaccination for the gastrointestinal cancer patients. AIM: Since the vaccination has been approved by our government medical support, we would evaluate the safety of the COVID-19 vaccination program in gastrointestinal cancer patients. METHODS: All gastrointestinal cancer patients who have been already diagnosed with cancer will be included in this study. The vaccine-related sign symptoms will be recorded and evaluated. The chemotherapy schedule was not been interrupted following the vaccination. The patient who refused to receive the second vaccination dose will be excluded from this study. RESULTS: Thirty-two patients were included in this study (our past 6-month evaluation from February till August 2021), colorectal adenocarcinoma was the most common gastrointestinal cancer according to organ-specific (25 patients), the others were gastric adenocarcinoma, pancreatic adenocarcinoma, and small bowel gastrointestinal stromal tumor. Both of them already received two doses of COVID-19 vaccine during this period, we reported there was no side effect related to these and the chemotherapy cycle has not been interrupted during vaccination. All of the patients could be tolerated it well and did not refuse to continue the treatment. CONCLUSION: There were no significant signs and symptoms of vaccine-related side effects on gastrointestinal cancer patients. COVID-19 vaccination during this pandemic and following the chemotherapy schedule on any kind of gastrointestinal cancer patients was safe and could be suggested as a routine protocol.

20.
Open Access Macedonian Journal of Medical Sciences ; 10:1818-1826, 2022.
Article in English | EMBASE | ID: covidwho-2066696

ABSTRACT

BACKGROUND: Severe acute respiratory syndrome has led to a pandemic of coronavirus disease 2019 (COVID-19). Malnutrition either biochemically or anthropometrically is a well-known risk factor for COVID-19 and may be the vice versa AIM: The objectives of this study were to investigate the prevalence of malnutrition in children infected with COVID-19 through evaluating the nutritional biomarkers such as serum electrolytes, serum albumin, and hemoglobin together with the anthropometric assessment. METHODS: A cross-sectional study that was conducted at El-Matria Teaching Hospital for all children admitted with confirmed COVID-19 for 6 months from February 1, 2021 to the end of July, 2021. Nutritional biochemical evaluation included serum electrolytes particularly the potassium and other nutritional biomarkers such as serum albumin and hemoglobin. Nutritional anthropometric evaluation depended on body mass index, the height/length, weight for length, and weight for height. The prevalence of malnutrition esp. hypokalemia was the main outcome. RESULTS: Hypokalemia was present in 21.8% of the study participants. Other nutritional biomarkers were found as hyponatremia, hypocalcemia, hypophosphatemia, and hypomagnesemia were detected in 49.1%, 38.2%, 21.8%, and 34.5% of the study subjects, respectively. Anthropometric malnutrition was present in most of the enrolled children with COVID-19 in the study (65.5 % [n = 36]) through which overweight and obese children occupied a greater percentage. CONCLUSION: Malnutrition either biochemically or anthropometrically could be linked to COVID-19 in children. COVID-19 could have negative outcomes on the nutritional status such as electrolytes disturbances. Both malnutrition and COVID-19 are considered synergistic associations.

SELECTION OF CITATIONS
SEARCH DETAIL