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1.
Journal of Hypertension ; 41:e108-e109, 2023.
Article in English | EMBASE | ID: covidwho-2246503

ABSTRACT

Objective: Since nutrition could extend lifespan even in stroke-prone rats developing stroke genetically, our WHO-Collaborating Center for Primary Prevention of Cardio-vascular Diseases (CVD) started world-wide hearth examination to investigate nutrition good for healthy longevity by collecting 24-hour urine (24U) samples. Design: Urinary biomarkers of nutritions, sodium for salt, potassium (K) for vegetables and fruits, isoflavones(Is) for soy, taurine(Ta) for fish and magnesium (Mg) for beans and nuts were analyzed in 24U among 4211 participants (49.7% females(F)), aged 48-56 years in 50 populations from 22 countries according to WHO-CARDIAC(Cardiovascular Diseases and Alimentary Compression) Study Protocol, and studied comparatively in 6 Japanese(J), 6 Mediterranean(M) populations from Greece, Italy(2), Spain(2), Portugal and 6 Euro-Western(EW) populations from Sweden, Ireland, Scotland, Canada, Australia, New Zealand. Results with Discussion: The quintile analyses of Ta and Mg/creatine ratio in the world were inversely associated with CVD risks. The Odds ratios of obesity, hypercholesterolemia and hypertension in the lowest quintile of both Ta and Mg were 6.3, 4.6 and 1.8, respectively. J and M populations had significantly higher Ta and Mg therefore, lower CVD risks than EW, but J and M took more salt increasing the risk of stroke (Table 1). Despite the high salt intake, M had the merit of significantly high K intake to attenuate the adverse salt effect. J had a merit to take Is from soy containing Mg. Since Is intake was inversely associated with lower BMI in the world populations, high Japanese Mg intake was related to high Is intake which was inversely associated with obesity in Japan. In fact, the Japanese populations who took significantly higher T and Mg had lower BMI as well as higher HDL and folic acid in the blood, expected to prevent atherosclerosis and dementia. In contrast to M and EW, particularly severe obesity over BMI 30 was obviously less in J, ranking 182nd among 190 populations (WHO). The mortality rates of COVID-19 were significantly positively related to the ratio of severe obesity among 20 major countries in the world and this mortality was obviously lower in J, suggestive of the potential of J diet for post-pandemic longevity. Conclusion: 24U biomarker analyses indicated low-salted J and M diets are recommendable for CVD prevention. J diet is so far better than M diet because of lower CVD risks such as obesity and lipidemia, which were proven by urinary biomarkers to be related with traditional fish and soy intakes.

2.
IEEE Journal on Selected Areas in Communications ; 41(1):107-118, 2023.
Article in English | Scopus | ID: covidwho-2245641

ABSTRACT

Video represents the majority of internet traffic today, driving a continual race between the generation of higher quality content, transmission of larger file sizes, and the development of network infrastructure. In addition, the recent COVID-19 pandemic fueled a surge in the use of video conferencing tools. Since videos take up considerable bandwidth ( ∼ 100 Kbps to a few Mbps), improved video compression can have a substantial impact on network performance for live and pre-recorded content, providing broader access to multimedia content worldwide. We present a novel video compression pipeline, called Txt2Vid, which dramatically reduces data transmission rates by compressing webcam videos ('talking-head videos') to a text transcript. The text is transmitted and decoded into a realistic reconstruction of the original video using recent advances in deep learning based voice cloning and lip syncing models. Our generative pipeline achieves two to three orders of magnitude reduction in the bitrate as compared to the standard audio-video codecs (encoders-decoders), while maintaining equivalent Quality-of-Experience based on a subjective evaluation by users ( n=242 ) in an online study. The Txt2Vid framework opens up the potential for creating novel applications such as enabling audio-video communication during poor internet connectivity, or in remote terrains with limited bandwidth. The code for this work is available at https://github.com/tpulkit/txt2vid.git. © 1983-2012 IEEE.

3.
International Journal of Intelligent Networks ; 4:19-28, 2023.
Article in English | Scopus | ID: covidwho-2244700

ABSTRACT

Growth in technology has witnessed the comfort of an individual in domestic and professional life. Although, such existence was not able to meet the medical emergencies during the pandemic COVID-19 and during other health monitoring scenarios. This demand is due to the untouched Quality of Service network parameters like throughput, reliability, security etc. Hence, remote health monitoring systems for the patients who have undergone a medical surgery, bed ridden patients, autism affected subjects etc is in need that considers postural change and then forward to the caretaker in hospitals through wireless body area networks (WBAN). Security in these data are very important as it deals with the life of a subject. In this work, a Hierarchical Energy Efficient Secure Routing protocol (HEESR) is proposed that categorizes the deployed body nodes in to direct node and relay node based on the threshold vale. Unlike other conventional protocols the cluster head selection is based on the energy levels and the traffic priority data like critical and non-critical data, followed by an optimal route to forward the acquired data is identified and the data is compressed using Huffman encoding technique and encrypted using asymmetric cryptographic algorithm for secure data transmission. This protocol mainly appends security and routing efficiency in a hierarchical pattern through data prioritization and out performs the other conventional routing protocols by yielding a better energy consumption of 6%, throughput 92% and security of 93%, which has balanced the packet drop rate considerably and deliver the data within the stipulated time period. © 2022 The Authors

4.
Medicine (United Kingdom) ; 51(1):80-85, 2023.
Article in English | Scopus | ID: covidwho-2243130

ABSTRACT

The incidence of cancer continues to rise, with an estimated 1 in 2 of the UK population born after 1960 diagnosed with malignancy at some point during their lifetime. This is in the context of an ageing population with increasing multimorbidity and polypharmacy. Cancer patients are frequent users of emergency care services and have a high rate of ambulance conveyance and hospital admission after review in emergency departments. Presentations can be a consequence of the cancer, its treatment or coexistent morbidity. Given the expanding armamentarium of cancer therapies, acute and general physicians are faced with a myriad of complex issues and require a knowledge of the broad principles of initial assessment, initial management and timely access to the wider multi-professional cancer team. © 2022

5.
International Journal of Pharmaceutical Sciences and Research ; 14(2):924-933, 2023.
Article in English | EMBASE | ID: covidwho-2243000

ABSTRACT

During the severe worldwide pandemic caused due to SARS COV-2 Corona virus, Favipiravir has been used for the treatment. It is a water insoluble anti-viral drug with poor dissolution and poor flow properties, resulting in poor oral absorption and less bioavailability. For a long time, the phrase "direct compression" was used to describe the compression of a single crystalline component into a compact without the addition of any other materials. Using excipients and solvents, the crystallo-co-agglomeration process aggregates drug crystals in the form of small spherical particles to create an intermediate product with better micromeritic and mechanical characteristics, solubility, and dissolution. Crystallo-co-agglomeration is a unique approach in which the pharmaceuticals or excipients are crystallized and agglomerated concurrently from a good solvent and/or bridging liquid by adding a non-solvent. The present study aims to formulate crystallo-co-agglomerates of Favipiravir to improve its physicochemical and mechanical properties. Results obtained during the evaluation showed that CCA technique could be successfully employed as an alternative to conventional wet agglomeration.

6.
Journal of Applied Science and Engineering (Taiwan) ; 26(3):313-321, 2023.
Article in English | Scopus | ID: covidwho-2241907

ABSTRACT

Video compression and transmission is an ever-growing area of research with continuous development in both software and hardware domain, especially when it comes to medical field. Lung ultra sound (LUS) is identified as one of the best, inexpensive and harmless option to identify various lung disorders including COVID-19. The paper proposes a model to compress and transfer the LUS sample with high quality and less encoding time than the existing models. Deep convolutional neural network is exploited to work on this, as it focusses on content, more than pixels. Here two deep convolutional neural networks, ie, P(prediction)-net and B(bi-directional)-net model are proposed that takes the input as Prediction, Bidirectional frame of existing Group of Pictures and learn. The network is trained with data set of lung ultrasound sample. The trained network is validated to predict the P, B frame from the GOP. The result is evaluated with 23 raw videos and compared with existing video compression techniques. This also shows that deep learning methods might be a worthwhile endeavor not only for COVID-19, but also in general for lung pathologies. The graph shows that the model outperforms the replacement of block-based prediction algorithm in existing video compression with P-net, B-net for lower bit rates. © The Author('s).

7.
Neurologic Clinics ; 41(1):193-213, 2023.
Article in English | Scopus | ID: covidwho-2241541
8.
Entropy (Basel) ; 25(1)2022 Dec 31.
Article in English | MEDLINE | ID: covidwho-2233544

ABSTRACT

Finding a vaccine or specific antiviral treatment for a global pandemic of virus diseases (such as the ongoing COVID-19) requires rapid analysis, annotation and evaluation of metagenomic libraries to enable a quick and efficient screening of nucleotide sequences. Traditional sequence alignment methods are not suitable and there is a need for fast alignment-free techniques for sequence analysis. Information theory and data compression algorithms provide a rich set of mathematical and computational tools to capture essential patterns in biological sequences. In this study, we investigate the use of compression-complexity (Effort-to-Compress or ETC and Lempel-Ziv or LZ complexity) based distance measures for analyzing genomic sequences. The proposed distance measure is used to successfully reproduce the phylogenetic trees for a mammalian dataset consisting of eight species clusters, a set of coronaviruses belonging to group I, group II, group III, and SARS-CoV-1 coronaviruses, and a set of coronaviruses causing COVID-19 (SARS-CoV-2), and those not causing COVID-19. Having demonstrated the usefulness of these compression complexity measures, we employ them for the automatic classification of COVID-19-causing genome sequences using machine learning techniques. Two flavors of SVM (linear and quadratic) along with linear discriminant and fine K Nearest Neighbors classifer are used for classification. Using a data set comprising 1001 coronavirus sequences (causing COVID-19 and those not causing COVID-19), a classification accuracy of 98% is achieved with a sensitivity of 95% and a specificity of 99.8%. This work could be extended further to enable medical practitioners to automatically identify and characterize coronavirus strains and their rapidly growing mutants in a fast and efficient fashion.

9.
Pharmakeftiki ; 34(4):156-165, 2022.
Article in English | EMBASE | ID: covidwho-2237831

ABSTRACT

Nebulizer therapy is an effective and safe treatment for respiratory diseases. Since the delivery of the pharmacologic agents to the lungs depends on the correct use of the inhalation device, the pharmacist, like the doctor must have all the skills in choosing a nebulizer, namely to be informed about the modern range of nebulizers, know the basic technical characteristics of these devices, their configuration, features of use, caveats for their use, as well as labeling and storage. Materials and methods. The following compressor devices were used as materials: nebulizer "Turbo Flow", trademark "Dr. Frei" (Great Britain), nebulizer "C102 TOTAL (NE-C102-E)" and "A3 Complete" of the trademark "OMRON" (Japan), nebulizer "LD-221 C" of the trademark "Little Doctor" (Singapore). Results and discussion. The article presents studies devoted to the research and analysis of the main technical parameters of modern compression nebulizers (nebulizer volume, speed spraying, the ability to adjust the size of particles in the aerosol cloud). The resulting knowledge will help working in tandem doctors and pharmacists to choose the right device for the effective delivery of the drug in the human the respiratory tract to achieve maximum therapeutic effect. Conclusions. Commodity analysis of compressor nebulizers available in Ukrainian pharmacies has been conducted. Analysis concern the range of nebulizers, the basic technical characteristics of these devices, their configuration, features of use, caveats for their use and conditions of storage. A comparative analysis of nebulizer chambers from different manufacturers was carried out and their main parameters were established. Labeling was studied and drew attention was drawn to the special information symbols that relate exclusively to nebulizers. Copyright © 2022, Zita Medical Managent. All rights reserved.

10.
Am J Emerg Med ; 2022 Nov 08.
Article in English | MEDLINE | ID: covidwho-2230130

ABSTRACT

A tracheobronchial rupture can be lethal. Its etiology in children varies and includes blunt trauma and iatrogenic injury. Most of the latter are associated with tracheal intubation, with other, iatrogenic causes scarcely being reported. We herein reported the first case of tracheobronchial rupture caused by chest compression during cardiopulmonary resuscitation. The present case highlights the importance of close follow-up after cardiopulmonary resuscitation, even if the patients are not intubated.

11.
12.
i-Manager's Journal on Computer Science ; 10(3):21-26, 2022.
Article in English | ProQuest Central | ID: covidwho-2226619
13.
J Hand Surg Asian Pac Vol ; 27(6): 1035-1037, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2214018

ABSTRACT

Coronavirus disease 2019 (COVID-19) continues to pose significant health challenges, with insights into long-term disease sequelae emerging. The post-viral effects resulting from COVID-19 are being investigated and 'long COVID-19' is now a recognised phenomenon. As part of the spectrum of comorbidities, acute-onset neuropathy is associated with infection. The public health response aimed at limiting morbidity and mortality is rooted in vaccination programmes. With the extensive roll-out of novel vaccinations, there has been careful monitoring of temporally associated health problems. Some of the documented associations include neuropathy and entrapment neuropathies. This case report details a patient presenting with bilateral carpal tunnel syndrome (CTS) post their second dose of AZD1222 (ChAdOx1 nCoV-19) vaccination. Though we do not claim causality, the emerging post-vaccination immune-mediated effects may ultimately be proven to include neuropathy exacerbation. Meticulous recording of such associations is required as it is of great relevance to the hand surgeon managing CTS. Level of Evidence: Level V (Therapeutic).


Subject(s)
COVID-19 Vaccines , COVID-19 , Carpal Tunnel Syndrome , Humans , Carpal Tunnel Syndrome/surgery , ChAdOx1 nCoV-19 , COVID-19/prevention & control , COVID-19 Vaccines/adverse effects , Median Nerve , Post-Acute COVID-19 Syndrome
14.
9th IEEE Uttar Pradesh Section International Conference on Electrical, Electronics and Computer Engineering, UPCON 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2213391
16.
Pakistan Journal of Medical and Health Sciences ; 16(10):679-681, 2022.
Article in English | EMBASE | ID: covidwho-2207083
17.
Circulation Conference: American Heart Association's ; 146(Supplement 1), 2022.
Article in English | EMBASE | ID: covidwho-2194360
18.
European Heart Journal, Supplement ; 24(Supplement K):K223, 2022.
Article in English | EMBASE | ID: covidwho-2188688
19.
Acta Clinica Belgica ; 77(Supplement 2):69-70, 2022.
Article in English | EMBASE | ID: covidwho-2187673
20.
Medicine (United Kingdom) ; 51(1):80-85, 2023.
Article in English | EMBASE | ID: covidwho-2181717
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