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1.
Pharmacopsychiatry ; 55(3):172, 2022.
Article in English | EMBASE | ID: covidwho-1967689

ABSTRACT

Introduction Safety studies have shown that COVID-19 vaccinations can provoke inflammatory processes in patients. The subsequent release of cytokines is accompanied by an increased inflammatory marker, C-reactive protein (CRP) [1]. For some antipsychotic drugs, inflammatory processes have been associated with increased drug levels, even above therapeutically approved ranges [2] [3]. It is not clear, whether this holds also true for COVID-19 vaccinations. Methods We present a case series comprising of 10 inpatients at the CIMH treated with an antipsychotic drug. Patients received a first, second or third dose of the COVID-vaccination Comirnaty in the morning. Blood samples were taken directly before the injection and were followed on day 1 and 4 while constant dosing. Blood testing included drug levels, safety laboratory, and CRP. Results CRP levels were elevated in nine patients;four of those also presented an increase in antipsychotic drug levels within a few days after COVID-19 vaccination. Blood level changes were i)+0%,+24%,+125%,+116% in quetiapine-, ii)+0%,+0%,+100% in olanzapine-, iii)+0,+42% in clozapine-treated patients, and iv)+205% in one risperidone-treated patient. As a result, three patients had drug levels above the therapeutically recommended range. Conclusion We present a series of patients with increased antipsychotic drug levels after COVID-19 vaccinations mediated via inflammatory processes. The intensity of inflammatory reactions strongly varies across patients. Hence, COVID-19 vaccinations may constitute an unpredictable risk factor for increased drug levels. Therapeutic drug monitoring can help to prevent safety risks in those patients with supra-therapeutic drug levels.

2.
Laryngo- Rhino- Otologie ; 101:S335, 2022.
Article in English | EMBASE | ID: covidwho-1967688

ABSTRACT

Purpose We investigated the prevalence of smell and/or taste loss and the clinical characteristics and recovery in a cohort of consecutive patients treated by two COVID-19 reference hospitals and evaluated the late persistence of hyposmia. Material and Methods 53 consecutive RT-PCR diagnosed patients (23 males, 30 females, 42,54 ± 10, 95 years) who had been hospitalized between January- June 2021 in the COVID-19 care wards were contacted, excluding patients with cognitive disorders and severe deconditioning. These patients (Group A) have been examined twice, once direct after leaving the hospital, and once again 4-6 weeks later. The patients- nasal and oral mucosa (Fungiform Papillae on tongue-s tip-fPap) were examined with a contact endoscope. Their olfaction was also examined with Sniffin' Sticks. As control-group we have examined 53 healthy subjects (Group B). Results Significant alterations in form and vascularization of fPap have been detect, specially by the first examination. Patients EGM-Thresholds of both measurements are higher than those of healthy subjects, although those of the second one are clearly lower. The same results have been found using Schniffin- Sticks. Discussion Our findings suggest that COVID-19 can produce a mild to profound neuropathy of multiple cranial nerves, which are responsible for the regeneration of fPap and the transmission of the chemical stimuli.

3.
Laryngo- Rhino- Otologie ; 101:S335, 2022.
Article in English | EMBASE | ID: covidwho-1967687

ABSTRACT

Background An olfactory disorder is often described as a characteristic initial symptom in patients with COVID-19 infection. The long-term olfactory disorders after a COVID-19 infection have not yet been described in detail. The aim of the study was to investigate the long-term effects of COVID-19 infections on smelling. Methods Patients with persistent, subjective smell &/ taste disorders were examined by means of questionnaires, endoscopic examinations, as well as side-separated olfactory testing using sniffin- sticks (TDI) and taste testing. After initial presentation and initiation of olfactory training, structured controls were performed for 72 patients six, 12 and 18 weeks after initial consultation. Results On average, the patient presented seven months after the onset of symptoms. 70 % of the patients were female and in average patients were 40 years old. Parosmia was reported by 64 % of the patients at this point. An at least unilateral functional anosmia was observed in 24 % and at least unilateral hyposmia in 71 % of the patients. A difference of ≥ 5 points in TDI between the respective sides could be identified in 35 %. During the first (six weeks), second (12 weeks) and third (18 weeks) control 32 %, 9 % and 14 % of the patients showed an improvement in smell of ≥ 5 points in the TDI test using sniffing sticks, respectively. Discussion Persistence of an olfactory disorder in the sense of hyp-/anosmia and parosmia can occur in young, female patients after COVID-19 infection. A side difference in smell can occur due to certain individual anatomy and the entry of the virus. A small proportion of patients with persistent olfactory disorders show regeneration.

4.
Laryngo- Rhino- Otologie ; 101:S335, 2022.
Article in English | EMBASE | ID: covidwho-1967686

ABSTRACT

Background Olfactory and gustatory disorders after COVID-19 vaccination have been described in the literature in case reports. These are mainly described after the Comirnaty vaccination. In this case report, the olfactory and gustatory disorders of two patients after Comirnaty vaccination are described. Methods The two affected patients with persistent subjective olfactory and/ or gustatory dysfunction after COVID-19 vaccination were evaluated using olfactory testing with Sniffin Sticks (TDI) and taste testing. Therapy was subsequently initiated and patients were followed up at regular intervals. Results 2 Patients (1 male and 1 female) with an average age of 80 years, who developed olfactory and/or gustatory disorders after the first and second vaccination respectively, were examined and tested. One case exhibited in the subjective and objective tests a functional anosmia (TDI: right 14.3, left 12.8) whilst the second case displayed hyposmia (TDI: right 18.75, left 21.75) and hypogeusia (right 4/16, left 6/16). Antibody testing showed the presence of IgG(S) but no IgG(Nc) was detected. Discussion Olfactory dysfunction in terms of hyp- or anosmia, as well as parosmia, may occur in patients after COVID-19 vaccination without previous COVID- 19-infection and should always be tested objectively. One case even exhibited hypogeusia. Despite laboratory diagnostics, previous COVID-19 infections cannot be ruled out with certainty. Age-related pre-existing disorders cannot be evaluated. Whether the course of olfactory dysfunction is comparable to that of patients after COVID-19 infection needs to be investigated in further studies.

5.
Laryngo- Rhino- Otologie ; 101:S334-S335, 2022.
Article in English | EMBASE | ID: covidwho-1967685

ABSTRACT

Introduction Loss of olfactory function is often the first and only symptom of an acute COVID-19 infection. A persistent loss of smell is also an expression of a long-COVID syndrome. Those affected complain of a long-lasting loss of smell and often also of a distorted odor perception, which only occurs later in the course and can severely impair the quality of life. Material and Methods From March 2021, 22 patients with a subjective olfactory disorder after a COVID-19 infection were examined at the University Hospital Augsburg. The subjective olfactory ability was recorded, the SDI test was carried out to determine the olfactory function as well as a taste test and an endoscopy of the nose. The severity of the parosmia was examined using a questionnaire. The patients received smell training for at least 3 months. Another examination was carried out 4-5 months later. Results 12 of the 22 patients showed hyposmia and 10 normosmia according to the SDI test. 17 of the patients reported that they had developed parosmia, 5 patients had no parosmia. After carrying out the olfactory training, there was a significant improvement in the olfactory ability measured by the SDI test, the subjective assessment of the olfactory ability differed greatly from the value measured in the SDI. Summary The study shows the typical occurrence of parosmias in the course of postviral olfactory disorders, which occur almost regularly in the case of an olfactory disorder caused by COVID-19. The study also clarifies the importance of olfactory training in the treatment of postviral olfactory disorders and the importance of carrying out an objective olfactory test, since the subjective assessment of the patient often does not reflect the actual olfactory ability.

6.
Laryngo- Rhino- Otologie ; 101:S324, 2022.
Article in English | EMBASE | ID: covidwho-1967684

ABSTRACT

Introduction As a result of the SARS-CoV-2 pandemic, a concept had to be devised in all clinics in order to ensure patient safety and staff protection. This included measures such as reducing patient numbers, introducing double triage and temporarily deploying treatment teams. The objective was to shorten the exposure time in order to protect against infection. The objective of this study was to examine the effects of these measures. Materials and Methods For the period July 2019 to July 2021, the numbers and treatment durations of all outpatient contacts during regular service from the hospital information system were analysed. Here, distinctions were made according to various treatment categories. Results Up to February 2020, the average number of patient contacts per month was 1669 ± 98. Following a reduced number of patient contacts from March 2020 due to the onset of the Coronavirus (1st lockdown), a highly significantly lower number of patients were treated as outpatients from May 2020 (1096 ± 141, p < 0.01). Prior to the pandemic, the mean treatment duration was 2.1 ± 0.1 hours, but later during the pandemic, only 1.5 ± 0.1 hours. The difference between both treatment durations was highly significant (p < 0.01). According to a comparison of treatment categories, only emergency patients appeared to have significantly longer maximum treatment durations than all other patient groups. Discussion:Even though compliance with all hygiene measures complicates the course of treatment, the main objective of shortening the duration of treatment was achieved. Mean and standard deviation represent 84 % of all patients. This parameter was incorporated into the clinic-s quality management system as a key figure that must be collected monthly.

7.
Laryngo- Rhino- Otologie ; 101:S321, 2022.
Article in English | EMBASE | ID: covidwho-1967683

ABSTRACT

Unquestionably the SARS-CoV-2 pandemic has become the biggest health concern globally for the past two years and an end to it is not in sight. The disease has a plethora of clinical features, but we decided to concentrate on a particular one-anosmia. The aim of this paper is to give a general introduction of the symptom-its prevalence, diagnostic significance, clinical outlines, management issues and financial and quallity of life impact and share our own experience managing 52 patients with similar symptoms using intranasal or oral corticosteroids and olfactory training. A comprehensive search was conducted using several electronic databases extracting relevant information regarding Covid-19 positive patients with anosmia. The included studies were published between March 2021 and October 2021. We found out that Covid-associated loss of smell is more frquent in females and an age under the age of 30. Ressolution of long term anosmia is achieved in over 80 % of cases. As newer information shines light on this topic it gives a better understanding of the pandemic. Introducing it in the general clinical presentation may help to curb the pandemic progression and present an understanding of long-term consequences of Covid-19.

8.
Laryngo- Rhino- Otologie ; 101:S320, 2022.
Article in English | EMBASE | ID: covidwho-1967682

ABSTRACT

Introduction We report on three patients, who presented themselves at our clinic between February and June 2021 with impaired voice, which resulted in an aphonia after having had Covid-19 infection. Material & methods Indirect laryngoscopy and videostroboscopy were performed in all patients. The voice quality was limited in all patients. Voice analysis was performed perceptively (RHB scheme) and objectively by computer-assisted analysis (Göttingen hoarseness diagram, voice field). Self-assessment was performed using the Voice Handicap Index (VHI). Results Laryngoscopically, all patients showed laterally mobile vocal folds, non-irritant mucosal conditions and a wide glottis. All patients showed wide, irregular vibration amplitudes and incomplete glottis closure by videostroboscopy. Objective voice analysis revealed pathological values for the irregularity and noise components as well as the Dysphonia Severity Index (DSI). In the VHI all patients documented a high-grade voice disorder with a mean score > 62. Our patients continued to suffer from dysphonia 6-9 months after initial presentation. Voice therapy did not provide satisfactory voice improvement. Discussion Whether glottic hypofunction is due to sensorimotor dysfunction caused by neurotropic coronavirus remains a conjecture. In addition, the hy-pofunction may be related to the general reduced performance of the patients in post-covid-syndrome. Conclusion According to our literature research, this is the first description of dysphonia as a possible symptom in post-covid-syndrome.

9.
Laryngo- Rhino- Otologie ; 101:S319-S320, 2022.
Article in English | EMBASE | ID: covidwho-1967681

ABSTRACT

Purpose In the CoViD-19 pandemy there is a need for voice examination techniques that minimize the risk of infection for both patient and examiner. To investigate whether the measurement of the Acoustic Voice Quality Index (AVQI) is valid and comparable to previous unmasked measurements if the speaker wears a surgical mask or a FFP-2 mask in order to reduce the risk of transmitting air-borne viruses such as SARS-CoV-2. Methods A convenience sample of 31 supposedly healthy participants was subjected to AVQI voice examination four times: Twice wearing no mask, once with a surgical mask and once with a FFP-2 mask as used regularly in our hospital. The order of the four mask conditions was randomized. The spread in the results between the two recordings without mask was then compared to the spread in the recordings with each mask and the recording without masks. Results The mean absolute difference in AVQI was 0.45 between the measurements without masks, 0.48 between no mask and surgical mask and 0.51 be-tween no mask and FFP-2 mask . The results were neither clinically nor statistically significant (in a signed rank test). Conclusion Based on a convenience sample of healthy or only mildly impaired voices wearing CoViD-19 protective masks does not substantially impair the results of AVQI measurements.

10.
Laryngo- Rhino- Otologie ; 101:S314, 2022.
Article in English | EMBASE | ID: covidwho-1967680

ABSTRACT

Background To date, systematic studies on the cause and prevalence of childhood hyposmia are lacking. The causes of this olfactory dysfunction can vary from simple adenoid hyperplasia or a condition following covid-19 infection to the rare Kallmann syndrome. Regardless of the entity, olfactory disorders can not only severely limit children's quality of life but also present a diagnostic challenge. Methods In the period from March to October 2021, 66 children (33 female, 33 male) between 5 and 18 years of age were examined. 41 of these children showed hyperplasia of the lymphatic tissue (adenoid vegetations and/or tonsillar hyperplasia). 25 healthy children without lymphatic hyperplasia were included in the control group. By means of the 'U-Sniff Test', an olfactory test validated for children, the preoperative olfactory ability was assessed. In addition to the known 12 olfactory sticks, we added two additional odors (chewing gum and ethanol). Results 39 % of the children with lymphoid hyperplasia showed a result below 8 points in the 'U-Sniff Test', while the controle group had regular test results. Children with lymphoid tissue hyperplasia were significantly more likely to be diagnosed with hyposmia than are children from the control group (p < 0.01). Odors unpleasant for children, such as fish or coffee, were more reliably detected than fragrant smells. The odor chewing gum was recognized by 91 % of the children in the age group under 6 years of age. The childrens origin or eating habits showed no correlation with their performance in the 'U-sniff Test'. Conclusion Children with lymphoid hyperplasia suffer significantly more often from hyposmia than children without adenoid/tonsillar hyperplasia. There is an evidence gap in the literature regarding this correlation.

11.
Laryngo- Rhino- Otologie ; 101:S313, 2022.
Article in English | EMBASE | ID: covidwho-1967679

ABSTRACT

Introduction The COVID pandemia led to a change in patient structure in German ENT clinics. Material/Methods The 30-day readmission rate of children in the ENT clinic of the Jena University Hospital from 01/01/2015 to 12/31/2015 was compared with the period from 07/01/2020 to 06/30/2021. Results In 2015, a total of 459 patients under the age of 18 were treated. In contrast, within one year of the COVID-19 pandemia, only 56 children and adolescents received inpatient therapy. Both groups were similar in terms of age and gender (group 2015: age 5.5 ± 4.4 years (mean ± standard deviation), 56 % male;group COVID-19: age 5.1 ± 3.4 years;58.9 % male). In 2015, 57.7 % of the patients were hospitalized for adenoid and / or tonsillar hyperplasia. In 2020/21 it was only 44.6 %. The 30-day readmission in the context of the COVID-19 pandemic was 12.5 %, significantly higher than in 2015 with 4.4 %. While only 30 % of readmissions were planned in 2015, this was 71.4 % at the time of the COVID-19 pandemic. In 2015, secondary bleeding was the cause of readmission in 20 %. In the context of the COVID-19 pandemic, there was not a single case of readmission due to secondary bleeding. Summary A changed patient spectrum due to the COVID-19 pandemic has an impact on the 30-day readmission rate of children in the ENT clinic. This must be taken into account in future therapy.

12.
Laryngo- Rhino- Otologie ; 101:S308, 2022.
Article in English | EMBASE | ID: covidwho-1967678

ABSTRACT

Introduction Symptoms and severity of SARS-CoV-2 infection vary greatly. Dizziness is a frequently reported symptom of SARS-CoV-2 viral infection. However, the extent to which this symptom is a result of the effect of SARS-CoV-2 on the vestibular system remains unclear. Material & methods In the present single-centre study, 50 patients with a previous SARS-CoV-2 infection underwent a vestibular assessment consisting of dizziness handicap inventory to assess dizziness during and after infection, clinical examination, video head impulse test and subjective visual vertical test (SVV). When SVV was abnormal, vestibular evoked myogenic potentials were performed. In addition, a retrospective data analysis of patients admitted to hospital presenting with acute symptoms of dizziness who were also diagnosed with acute SARS-CoV-2 infection was performed. Results During and after the SARS-CoV-2 infection, women were significantly more likely to suffer from dizziness than men. A significantly reduced semicircular canal or otolith function was not observed in either women or men. Acute SARS-CoV-2 infection was diagnosed in three patients who presented to with acute vestibular syndrome. One of the patients exhibited acute peripheral unilateral vestibulopathy upon diagnosis. A different patient was diagnosed with vestibular migraine and another with a posterior inferior cerebellar artery infarct. Conclusion Past SARS-CoV-2 infection does not usually lead to a hypofunction of the vestibular organs. However, individual patients with acute infection have been reported to show symptoms of acute vestibular syndrome. Although the underlying pathomechanism has not yet been elucidated, SARS-CoV-2-induced neuropathy or ischemia should be considered in the differential diagnosis.

13.
Laryngo- Rhino- Otologie ; 101:S307, 2022.
Article in English | EMBASE | ID: covidwho-1967677

ABSTRACT

Introduction As part of the immune response to the COVID-19-vaccine a multitude of anti-COVID-antibodies is formed. A part of these antibodies can bind to the body-s own tissue and facilitate autoinflammatory processes. Such autoimmune-inflammatory processes are suspected to be behind various symptoms of the COVID disease and the long-COVID syndrome. So far, numerous reports on neuro-otological symptoms in the context of COVID infection have been published. The present report describes patients who presented in a university ENT outpatient department with vestibulo-cochlear symptoms in connection with a COVID vaccination. Methods All patients who presented with dizziness, tinnitus and hearing impairment for the first time in a direct temporal context (max. 3 days after vaccination) tot he vaccination were examined by an ENT specialist and further examined using subjective and objective audiometry and, depending on the symptoms, using vestibular diagnostics. Results An otitis media was not found in any patient. A cochlear genesis of the vestibulo-cochlear symptoms could be demonstrated in all patients. One patient has isolated symptoms with hearing loss, all others also suffered from tinnitus or dizziness. In all patients, the symptoms resolved after drug therapy was carried out. Discussion Vaccine-associated hearing loss has also been described in the case of influenza vaccination. We were unable to provide direct evidence of the COVID vaccination as the triggering factor for the vestibulo-cochlear symptoms. An association of these symptoms with the vaccination cannot be ruled out though. The most likely mechanism is an immunoglobulin-triggered specific autoimmune response.

14.
Laryngo- Rhino- Otologie ; 101:S296, 2022.
Article in English | EMBASE | ID: covidwho-1967676

ABSTRACT

Introduction Sudden sensorineural hearing loss (SSNHL) is defined as a hearing loss occurred within 3 days with decreasing of hearing level at least 30 dB in as a minimum three frequencies. The exact etiology and pathology of SSNHL is still unknown and the causes can be identified in only 10 to 15 percent of diagnosed cases. Methods Goal: To study the correlation of SSNHL and Covid-19 infections. We selected 10 patients who came to our clinic with SSNHL and who recently recovered from Covid-19 infection. They were admitted to clinic on 20-25th days of their COVID-19 infection, all selected patients were received remdesivir, intravenous steroids and plasma exchange to treat their COVID-19 infection and clinically improved. During 1-3 weeks of the treatment their noticed left-sided tinnitus and SSNHL. They all had no previous ear pathology. Results On ear examination external auditory canal canals and tympanic membranes are normal, were found negative Rinne's test on left side and Weber's test lateralising to the opposite side, tympanogram type A, no acoustic reflexes on left ear. When performed laboratory tests after 2 months of post-onset of SSNHL in all patients were found a positive COVID-19 IgG antibodies which showing initial time of SSNHL incidence. Such as, was not found any other risk factors for evolving SSNHL except Covid-19, so we came to conclusion, that the patient's SSNHL is complication of COVID-19 infection and probably this infection can cause unilateral intralabyrinthine or intracochlear hemorrhage, damages the inner ear's delicate hair cells and/or the blood supply.

15.
Laryngo- Rhino- Otologie ; 101:S292, 2022.
Article in English | EMBASE | ID: covidwho-1967675

ABSTRACT

The majority of firework-related injuries in Germany are found at the turn of the year. With regard to hearing, a distinction is made between blast (BT) and explosion trauma (ET). The study examines the prevalence and characteristics of firework-related injuries over the past 11 years on New Year's Eve and compares these with the effects of the pyro ban 2020/21 imposed due to the COVID-19 pandemic. A retrospective chart review of all patients who presented themselves with the diagnosis blast trauma (H 83.3) or explosion trauma (T 70.8) at the Charité emergency service in the last 11 years from December 28 to January 5 was performed. 267 patients were recorded (78 % male). 1/3 each were assigned to the age group 10-19 and 20-29 years. 21 % of the patients were admitted to the hospital. There was an isolated BT of the ear in 66 %, hand injuries in 12 %, head injuries in 8 % and eye injuries in 4 %. 87 % had ear involvement with hearing loss: 83 % with tinnitus, 5.6 % with ET. The tone audiograms of BT and ET show differences only at 6 kHz, but not at 4 kHz. 8.6 % of the patients underwent surgical interventions. The treatment of a tympanic membrane perforation was carried out by: 54 % splinting vs. 38 % tympanoplasty. Therapy with a glucocorticoid was administered i.v. in 48 % and initiated orally in 17 %. Overall, there was a decrease in injuries of almost 90 % in 2020/21 compared to 2017/18. The use of fireworks leads to increased utilization of health care resources. The ban on the sale of pyrotechnics as well as the introduction of pyro ban zones in 2020 led to a relevant decrease in injuries. 2020 was the only year in which there were no injuries in children / adolescents. The BT of the ear is the most common firework-related injury.

16.
Laryngo- Rhino- Otologie ; 101:S203, 2022.
Article in English | EMBASE | ID: covidwho-1967674

ABSTRACT

Introduction The imposed radical governmental restrictions to combat the pandemic and the overstrained medical resources affected greatly, not only those infected from the novel virus, but also miscellaneous patient groups. Aim of this study was the assessment of the efficacy of oncologic healthcare during Covid-19 pandemic on patients with head neck squamous cell carcinoma in a tertiary university hospital in Germany. Material and Methods This retrospective, cross-sectional, observational study included 94 patients with newly diagnosed head and neck squamous cell carcinoma during a two-year period. Patients were assigned to two date-dependent groups;referrals before (Group A) and during (Group B) the Covid-19 pandemic. Time intervals from symptom(s) onset to diagnosis, diagnosis to treatment and treatment initiation to completion were recorded. Furthermore, TNM-stages and application of reconstructive surgery with free tissue transfer were determined. Results Despite the challenges and burden of the pandemic, tumor upstaging and treatment delays could not be observed. Conclusion A timely diagnosis and treeatment initiation plays a major role in prognosis of patients withs head and neck squamous cell carcinoma.

17.
Laryngo- Rhino- Otologie ; 101:S198-S199, 2022.
Article in English | EMBASE | ID: covidwho-1967673

ABSTRACT

Objective The objective of this study was to determine if patients with Neurofibromatosis Type 1 (NF1) have an impaired sense of smell or taste. Neurofibromin, the NF1gene protein product is ubiquitous in the body and is especially associated with the development of neurogenetic structures. Lately enlarged olfactory bulbs have been described in patients with NF1. Until now, there is no study to evaluate the sense of smell and taste in patients with NF1. Method This study has been approved by the Hamburg Ethics committee. An evaluation of the sense of smell and taste was undertaken in 26 patients with NF1 using the Burghart Sniffin' Sticks. Three patients were excluded due to a prior infection with the Corona virus. As a control group the same examination was performed in healthy individuals (same sex/ same age as the NF1 patients) by the same examiner. Results Preliminary results show a normal sense of smell in patients with NF1. The morphologic finding of enlarged olfactory bulbs seem to have no functional equivalent. However, 8 out of 23 patients with NF1 had difficulties identifying at least one taste flavor. The data collection of the control group is still ongoing, thus far none of the study participants misidentified a taste flavor. A statistical significance is aimed at by increasing the case numbers.

18.
Laryngo- Rhino- Otologie ; 101:S197, 2022.
Article in English | EMBASE | ID: covidwho-1967672

ABSTRACT

The Covid-19 pandemic situation over the past two years has placed considerable stress on the medical treatment facilities. The therapy and prognosis of head and neck cancer (HNC) depends largely on the time of diagnosis. In the medical subjective perception, HNC were diagnosed later under pandemic conditions for various reasons, such as additional fear of visiting a doctor and postponed examinations by the medical staff. For some sub-areas of medicine, valid studies are already available. With the help of an evaluation of the UICC tumor stages at diagnosis, it is intended to retrospectively determine whether the most common HNC in 2020 and 2021 were diagnosed later than in 2018 and 2019. The UICC stages of all (n = 207) laryngeal, oropharyngeal, hypopharyngeal and oral cavity carcinomas primarily treated at the Halberstadt Otorhinolaryngology Clinic were evaluated for the diagnosis periods 2018/2019 and 2020/2021 (until November 2021). Overall, there was no evidence of an increase in tumor stages in 2020/21 compared to 2018/19. Even an evaluation of the subgroups with a view to the stages at the time of diagnosis does not reveal any evidence of a significant delay due to the pandemic situation. Despite temporary logistical restrictions, it has apparently been possible to prevent an extension of the diagnostic periods for the most common head and neck tumors.

19.
Laryngo- Rhino- Otologie ; 101:S193-S194, 2022.
Article in English | EMBASE | ID: covidwho-1967671

ABSTRACT

Introduction According to international publications the COVID-19 pandemic led to a delay in the medical treatment of different diseases. The purpose of our investigation was to evaluate the incidence and the stage of head and neck cancer in the period from 01/2020-12/2021. These data were compared to that before the pandemic in the time period from 01/2018-12/2019. Method Using our oncological documentation system, a monocentric analysis of the number of tumor diagnosis and tumor stages at initial diagnosis was carried out looking at the 2-year pandemic period from 2020-2021. The purpose of the investigation was to determine whether there was a pandemic-related delay in treatment of oncological patients in our clinic. Results The analysis showed no decrease in the number of new tumor cases in the pandemic years 2020-2021 compared to the years 2018-2019. Furthermore, no shift towards more advanced tumor stages during the COVID-19 pandemic could be determined. Conclusion Occasionally the COVID-19 pandemic led to delayed tumor diagnosis and treatment, which resulted in a worse outcome for many patients. This effect could be turned around by accurate appointment planning taking tumor suspected cases under consideration. Furthermore, special office hours particularly for tumor cases even in times of a lockdown including video consultations when appropriate and patient awareness campaigns led to a favorable patient care.

20.
Laryngo- Rhino- Otologie ; 101:S355, 2022.
Article in English | EMBASE | ID: covidwho-1967670

ABSTRACT

Background Face-to-face teaching is the predominant teaching method at universities. It is questioned during contact restrictions as well as in the background of digital transformation. The aim of this study was to evaluate to what extent a clinical round as an interactive video stream can be used as a substitute to conventional onsite teaching in otorhinolaryngology. Material and Methods Forty-three students were included in the research. Instead of conventional clinical round in otorhinolaryngology, teaching was done live using an iPad in interaction with students at home. Evaluation forms were used to assess the subjective didactic value of different visualization formats and resulting learning experiences for the students. Results The majority of students (93.02 %) indicated an added value of the e-visit, especially as a good alternative to the traditional attendance practicum during attendance restrictions (69.77 %). Both the quality of the video transmission and the audio transmission were consistently rated as good to very good. Conclusions The use of new interactive visualization capabilities in teaching is a good alternative or complement to traditional teaching, especially in the context of diseases or pandemics (Covid-19 pandemic).

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