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1.
JACCP Journal of the American College of Clinical Pharmacy ; 5(12):1359, 2022.
Article in English | EMBASE | ID: covidwho-2173023

ABSTRACT

Service or Program: Operation Allies Welcome was a unified national humanitarian mission to support Afghanistan evacuees in the United States. The City of Philadelphia, Pennsylvania welcomed approximately 25,000 evacuees from Afghanistan between August and November 2021. This effort included a broad range of medical services including COVID-19 testing, vaccinations, and setting up a medication dispensary. Our pharmacy team was tasked with establishing and operating a dispensary to dispense limited supply of medications to patients for non-life-threatening conditions as they were bridged to definitive care. The objective of this is to describe the pharmacists' role within this coordinated emergency response. Justification/Documentation: This emergency response required that our pharmacy dispensary was adequately staffed and stocked with common medications for the target population. Our roles focused on establishment of standard operating procedures for the dispensary, dispensing medications, creation of a securely shared electronic inventory, creation of standardized staffing process, participation in vaccination efforts, and provision of drug-information. Overall, 1363 prescriptions, for both over the counter (OTC) and prescription medications, were dispensed. The dispensary stocked 82 different medications. Antipyretics, analgesics, antihistamines, prenatal vitamins, proton-pump inhibitors, and topical antibiotics were the most commonly dispensed OTC products. Frequently dispensed prescription medication classes included antibiotics, steroids, antiemetics, anti-diabetic and antihypertensives agents. We successfully leveraged the support of 66 volunteer pharmacists from 9 organizations around Philadelphia, including academic, hospital, non-profit, and pharmaceutical industry institutions. Adaptability: This program has a high level of adaptability for future emergency preparedness efforts. It serves as a playbook to guide pharmacists to respond to future emergencies. Significance: Our service provided much needed pharmacy support for Afghan evacuees. Our practical experiences demonstrated that pharmacists can effectively create and implement a dispensary during emergent crises. Findings from our operation add to the limited literature supporting the importance of pharmacists in these coordinated emergency responses.

2.
ONdrugDelivery ; 2022(129):12-15, 2022.
Article in English | EMBASE | ID: covidwho-2169287

ABSTRACT

In this article, Tom Oakley, Director of Drug Delivery Device Development, Springboard, looks at some of the current trends in the drug delivery industry and projects some of the key factors that will influence drug delivery decision making in 2022. Copyright © 2022, Frederick Furness Publishing. All rights reserved.

3.
Pharma Times ; 52(5):24-25, 2020.
Article in English | EMBASE | ID: covidwho-2169075
4.
Pharma Times ; 52(12):46-48, 2020.
Article in English | EMBASE | ID: covidwho-2168966
5.
Pharma Times ; 52(12):11-15, 2020.
Article in English | EMBASE | ID: covidwho-2168578
6.
Pharma Times ; 52(5):40, 2020.
Article in English | EMBASE | ID: covidwho-2168438
7.
Pharma Times ; 52(4):33, 2020.
Article in English | EMBASE | ID: covidwho-2168437
8.
ONdrugDelivery ; 2022(136):12-14, 2022.
Article in English | EMBASE | ID: covidwho-2168115

ABSTRACT

In this article, Sara Dorman, Global Biopharma Market Manager at Roquette, discusses the benefits of single-use systems, including how they help accelerate a drug product's journey to market securely and more sustainably. Copyright © 2022, Frederick Furness Publishing. All rights reserved.

9.
Community Practitioner ; 95(6):9, 2022.
Article in English | ProQuest Central | ID: covidwho-2167534

ABSTRACT

NHS leaders have told governments what UK and Welsh funding priorities should be in future budgets as fears grow some Welsh NHS organizations will not break even this financial year. According to a new paper by the Welsh NHS Confederation, government needs to review the long-term funding model for health and social care because without further investment, patient experience and quality of care will suffer. NHS leaders say funding priorities should include the ongoing costs of Covid-19, recovery of care services, the backlog in elective care and the maintenance of NHS estates -- including reducing carbon emissions. The rising cost of healthcare was blamed on Covid-19, a growing and ageing population, developments in medical technology, increases in energy prices, pay and price inflation, pharmaceutical developments, and recruitment and retention challenges, while both demand on, and expectations of, the NHS continue to increase.

10.
Journal of Pharmaceutical Negative Results ; 14:59-67, 2023.
Article in English | EMBASE | ID: covidwho-2206832

ABSTRACT

This study aims to analyze the valuation and quantification of assets, liabilities and income in pharmaceutical companies in Indonesia. This research is qualitative in nature, namely research that holistically intends to understand the phenomenon of what is the subject of research, be it events, perceptions, or actions, and in a descriptive way the approach used uses a conceptual approach, and literature studies The results of the study show that valuation and asset quantification use three approaches, namely the market data comparison approach, the revenue capitalization approach and the cost approach, where pharmaceutical companies in Indonesia tend to use these three approaches in assessing assets, then the debt policy of pharmaceutical companies in Indonesia when viewed from the the debt to equity ratio shows a fluctuating value where the risk of debt is still high for the company due to the high value of this ratio, furthermore the income of pharmaceutical companies in Indonesia tends to fluctuate where during the covid 19 pandemic pharmaceutical companies experienced significant revenue growth. Copyright © 2023 Wolters Kluwer Medknow Publications. All rights reserved.

11.
Journal of Pharmaceutical Negative Results ; 13:3741-3745, 2022.
Article in English | EMBASE | ID: covidwho-2206773

ABSTRACT

The pharmaceutical supply chain is very crucial for the overall industry. A crucial role is played by the Indian Pharmaceuticals industry when we consider the global pharmaceuticals industry. Indian pharmaceutical industry fulfils a large portion of the global pharmaceutical demand. After Covid-19 pandemic, many retail outlets have mushroomed everywhere in India though it is good for the business development, it puts a lot of pressure on the existing infrastructure of the supply chain. The level of responsiveness of the supply chain determines how quickly it can satisfy consumer demand. The pharmaceutical industry is ensuring good service levels as it operates at a 95 percent service level. This research paper identifies challenges in pharmaceutical supply chain. Researcher also narrowed down these challenges into two as Supply chain responsiveness and Service level. Here researcher suggested that to enhance Supply chain responsiveness and Service level, pharmaceutical industry should apply new techniques such as AI & ML. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

12.
Journal of Pharmaceutical Negative Results ; 13:2943-2948, 2022.
Article in English | EMBASE | ID: covidwho-2206763

ABSTRACT

The development of profits generated by the company illustrates the company's success in carrying out operational activities and becomes a measuring tool for investors in making decisions. The purpose of this study is to determine the Cost-Volume-Profit Relationship and Sales Mix Concept in Pharmaceutical Companies in Indonesia. CVP analysis examines the behavior of total revenue, total cost, and operating profit as changes that occur in units sold, selling price, variable costs per unit, or fixed costs, and sales mix is the relative proportions in which a company's products are sold. Different products have different selling prices, cost structures, and contribution margins. To analyze fairness, disclosure, and future trends in accounting for Pharmaceutical Companies, a qualitative descriptive approach was chosen. The fundamental characteristic of the qualitative descriptive method is the use of naturalistic data or non-numeric data without variable intervention. Descriptive approach is also known as case study research, which involves studying a particular situation to find out whether a general theory can emerge from the research, or whether an existing theory emerges from a particular situation. The profit target has shrunk sharply when compared to during the COVID-19 pandemic. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

13.
Journal of Pharmaceutical Negative Results ; 13:6113-6121, 2022.
Article in English | EMBASE | ID: covidwho-2206750

ABSTRACT

COVID-19 waves were the deadliest health crisis faced by the residents of planet earth in the 21th century. This outbreak of SARV-CoV-2 virus and its variants has impacted nearly all of the world in a short window of 16 months. Almost all the nations in the world had maintained a complete lockdown in all the spheres to withstand this medical health emergency. Thus, COVID-19 has a deep impact on the global economy and commerce because of lockdowns, and limited movements as defined in COVID-19 protocol guidelines for its prevention. The trade modalities of the pharmaceutical industry, which is already being governed under the TRIPS and WHO agreements, also got effected like other sectors of the economy. The significant setbacks for the pharmaceutical industry were the disruptions in the operations due to clogged supply chains of raw materials and stalled production units. On the contrary, the opportunity for the invention of vaccines provides the spur for research and development. Certainly, the prices of the drugs and marketing strategies have also been adjusted during this period. In this paper, authors have tried to trace and survey the combined effects of COVID-19 and TRIPS on the pharmaceutical industry's marketing manoeuvres and the prices of the drugs. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

14.
Journal of Pharmaceutical Negative Results ; 13:4845-4852, 2022.
Article in English | EMBASE | ID: covidwho-2206744

ABSTRACT

This study aims to investigate the relationship between director's salary and financial performance of top 10 BSE Listed companies for the period of 3 years i.e. 2019-2021. Remuneration of director pays a vital role for the interest group of companies moreover it impacts the company's financial performance. Financial performance of the company is being judged by various financial ratio i.e. NPR, DE, ROCE, CR, ROA. Secondary data have been collected from the official website of the company. E views have been used to investigate the correlation between Directors remuneration and Financial performance. Our study indicates that director's remuneration has significant impact on financial performance. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

15.
Pharmacy Education ; 22(5):36, 2022.
Article in English | EMBASE | ID: covidwho-2206510

ABSTRACT

Introduction: In the last years, the pharmacist has performed a new range of activities, from traditional medicines dispensing to patient-centred services. In many countries, the implementation of pharmaceutical services has showed significant benefits for public health systems. During the COVID19 pandemic, pharmacists had assumed additional responsibilities and adapted their activities. Nevertheless, in Romania the legal framework and definition of pharmaceutical services have been recently established. Objective(s): The aim was to identify recent legislative changes contributing to the implementation of Romanian pharmaceutical services. Moreover, the author has highlighted some new activities performed by pharmacists throughout the COVID19 pandemic. Method(s): Data was collected by searching national authorities' databases (Ministry of Health, the College of Pharmacists from Romania, National Institute of Public Health). Electronic databases (mainly PubMed and Google Scholar) were searched to identify new responsibilities of pharmacists after March 2020. Then, information was extracted, analysed and discussed. Result(s): In November 2020, an official definition of the pharmaceutical services was introduced due to the completion of the Romanian Pharmacy Law no. 266/2008. Another important event for the future of the profession was the approval of the list of pharmaceutical services (Ministry of Health Order No. 2382, November 4, 2021), divided into essential and advanced services. The legal framework could be correlated with a positive change regarding the pharmacy residency training (three year duration) and the number of specialist pharmacists. In 2019, there were reintroduced two specialties, like Pharmaceutical Industry and cosmetology and General Pharmacy, in addition to Clinical Pharmacy and Clinical Laboratory. Consequently, the number of places increased with 32% in 2019 comparing with 2018, respectively 63% in 2020, as a measure of the authorities to increase the health personnel due to the pandemic. During the national state of alert, more than 9% of the pharmacy residents had to fullfil a new professional role and to provide assistance to public health departments concerning COVID-19 public support. Through the order of the head of the department for emergency situations, they were sent to airports, ambulance service, COVID19 call-centres or other administrative departments in the period January 2021-March 2022. In addition to activities carried out usually, such as dispensing, counseling, measuring biological parameters (high blood pressure, blood sugar), community pharmacists were allowed to perform rapid antigen tests for COVID-19 after May 10, 2021. Until the 1st January 2022, there were 137 temporary authorised community pharmacies in Romania. Conclusion(s): The approval of the Romanian official list of pharmaceutical services represented the first step for expanding the role of the pharmacist and his contribution to the healthcare system. As drug professionals, pharmacists are a valuable resource. During the pandemic, pharmacists were in the first line and had an active role in helping patients, proving the ability to adjust and offer new services. Therefore, in the future, regulators should consider integrating pharmacists in medical multidisciplinary teams, with benefits for patient care and health systems.

16.
NeuroQuantology ; 20(18):252-259, 2022.
Article in English | EMBASE | ID: covidwho-2203993

ABSTRACT

Indian witnessed its record lowest ever currency fall in a matter of few days. The Rupee loss meant that it's a gain for the US Dollar. There have been numerous reasons which paved way to the diminishing value of Indian rupee. Within a timeframe of just 75 years a sharp rise to 79INR/1USD could be witnessed in the year 2022. The value of Rupees has diminished by about seventeen times during this time frame. There has been numerous reasons for the fall in the vale of Rupee such as the Russia-Ukraine war, inflation rate, crude oil price change etc. the fall in Rupee value has put the Indian economy in great stress and challenge creating an impact on the economy. This paper attempts to make a Rupee-Dollar comparison since 2016 to 2022 using data collected from reliable sources and using SPSS software to evaluate the results obtained. Copyright © 2022, Anka Publishers. All rights reserved.

17.
Bioanalysis ; 14(19):1251-1255, 2022.
Article in English | Web of Science | ID: covidwho-2202152

ABSTRACT

Approximately 280 people from pharmaceutical industries, contractors, academic institutions and regulatory authorities attended the 13th Japan Bioanalysis Forum Symposium. The symposium was held via web to prevent the spread of COVID-19 from the 28 February to 2 March 2022. The theme of the symposium was 'All for One Goal', and the event has provided an opportunity for open discussion among researchers with different backgrounds but who share a common goal: "to deliver more effective and safe pharmaceuticals to patients as quickly as possible". The speakers focused on hot topics in bioanalysis, including chromatography, biomarker analysis, cell and gene therapy, COVID-19 and antidrug antibody. This symposium provided a great opportunity for the participants to have meaningful discussions, even though 'on the web' was a limited space.

18.
Indian Journal of Pharmacology ; 54(5):364-372, 2022.
Article in English | MEDLINE | ID: covidwho-2201806

ABSTRACT

Traditional drug development is a tedious process with involvement of enormous cost and a high attrition rate. Outsourcing drug development services to contract research organizations (CROs) has become an important strategy for cost and risk reduction, capacity building, and data generation. The therapeutic and operational expertise of these CROs has allowed pharmaceutical industry to reduce in-house infrastructure as well as research capacity. Working with specialized CROs has not only increased the rate of success but also the speed of drug discovery process. Small firms with promising molecules but limited resources and large firms interested in diversifying their dimensions are utilizing the services of efficient CROs. Globally, approximately one-third of the drug development processes are now being outsourced and the data generated by the independent third party are well appreciated during regulatory submissions. In this article, we discuss the international and national trends, outsourcing services and models, key considerations while selecting CRO, and benefits and challenges of outsourcing. Further, we discuss how the technical expertise of competent CROs was utilized when traditional ways of conducting clinical trials were disrupted by the COVID-19 pandemic. Taken together, the increasing health-care demands, COVID-19 pandemic or any other such upcoming health crisis, and recent advances in advanced technologies (machine learning and artificial intelligence, etc.) are likely to fuel global CRO market in the coming years.

19.
Biomolecules ; 12(12) (no pagination), 2022.
Article in English | EMBASE | ID: covidwho-2199739
20.
Journal of medical Internet research ; 09, 2022.
Article in English | EMBASE | ID: covidwho-2198052

ABSTRACT

BACKGROUND: Within a few months, the COVID-19 pandemic has spread to many countries and has been a real challenge for health systems all around the world. This unprecedented crisis has led to a surge of online discussions about potential cures for the disease. Among them, vaccines have been at the heart of the debates, and have faced lack of confidence before marketing in France. OBJECTIVE(S): This study aims to identify and investigate the opinion of French Twitter users on the announced vaccines against COVID-19 through sentiment analysis. METHOD(S): This study was conducted in two phases. First, we filtered a collection of tweets related to COVID-19 available on twitter from February to August 2020 with a set of keywords associated with vaccine mistrust using word embeddings. Second, we performed sentiment analysis using deep learning to identify the characteristics of vaccine mistrust. The model was trained on a hand labeled subset of 4,548 tweets. RESULT(S): A set of 69 relevant keywords were identified as the semantic concept of the word "vaccin" (vaccine in French) and focus mainly on conspiracies, pharmaceutical companies, and alternative treatments. Those keywords enabled to extract nearly 350k tweets in French. The sentiment analysis model achieved a 0.75 accuracy. The model then predicted 16% of positive tweets, 41% of negative tweets and 43% of neutral tweets. This allowed to explore the semantic concepts of positive and negative tweets and to plot the trends of each sentiment. The main negative rhetoric identified from users' tweets was that vaccines are perceived as having a political purpose, and that COVID-19 is a commercial argument for the pharmaceutical companies. CONCLUSION(S): Twitter might be a useful tool to investigate the arguments of vaccine mistrust as it unveils a political criticism contrasting with the usual concerns on adverse drug reactions. As the opposition rhetoric is more consistent and more widely spread than the positive rhetoric, we believe that this research provides effective tools to help health authorities better characterize the risk of vaccine mistrust.

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