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1.
Int J Infect Dis ; 125: 170-176, 2022 Oct 29.
Article in English | MEDLINE | ID: covidwho-2086294

ABSTRACT

OBJECTIVES: An unusual increase in Salmonella enterica serovar Paratyphi A infection rate in Japanese travelers returning from Myanmar was observed in 2015. METHODS: We analyzed epidemiologic data of returned travelers with enteric fever from 2005-2019. We also analyzed 193 Salmonella Paratyphi A isolates, including 121 isolates with published genomes. RESULTS: Annual notification trends showed a rapid increase in Salmonella Paratyphi A infection in travelers returning from Myanmar in 2015: 2-4 cases/100,000 travelers in 2012-2014 and 13 cases/100,000 travelers in 2015 (P <0.001). The genomic analyses revealed that 11 Myanmar-related isolates in 2015 formed a tight cluster in clade 3 with a single nucleotide variant (SNV) distance of 0-11 (primarily 0-7), yielding a wider SNV range than outbreak-associated isolates from Cambodia in 2013 (0-6 SNVs) or China in 2010 (0-5 SNVs). Although all Cambodia-related isolates in 2013 harbored the wild-type gyrA sequence, all Myanmar-related isolates in 2015 had a single, identical mutation (Ser83Phe) in the gyrA gene. CONCLUSION: The epidemiologic and molecular investigations suggested an increase in the infection rate with genetically closely related Salmonella Paratyphi A in travelers returning from Myanmar in 2015. Careful monitoring of the infection in Myanmar as an endemic country is warranted, considering the resumption of cross-border travel during the COVID-19 pandemic.

2.
Lancet Planetary Health ; JOUR(8):E670-E681, 6.
Article in English | Web of Science | ID: covidwho-2081692

ABSTRACT

Background Household overcrowding is a serious public health threat associated with high morbidity and mortality. Rapid population growth and urbanisation contribute to overcrowding and poor sanitation in low-income and middle-income countries, and are risk factors for the spread of infectious diseases, including COVID-19, and antimicrobial resistance. Many countries do not have adequate surveillance capacity to monitor household overcrowding. Geostatistical models are therefore useful tools for estimating household overcrowding. In this study, we aimed to estimate household overcrowding in Africa between 2000 and 2018 by combining available household survey data, population censuses, and other country-specific household surveys within a geostatistical framework. Methods We used data from household surveys and population censuses to generate a Bayesian geostatistical model of household overcrowding in Africa for the 19-year period between 2000 and 2018. Additional sociodemographic and health-related covariates informed the model, which covered 54 African countries. Findings We analysed 287 surveys and population censuses, covering 78 695 991 households. Spatial and temporal variability arose in household overcrowding estimates over time. In 2018, the highest overcrowding estimates were observed in the Horn of Africa region (median proportion 62% [IQR 57-63]);the lowest regional median proportion was estimated for the north of Africa region (16% [14-19]). Overall, 474.4 million (95% uncertainty interval [UI] 250.1 million-740.7 million) people were estimated to be living in overcrowded conditions in Africa in 2018, a 62.7% increase from the estimated 291.5 million (180.8 million-417.3 million) people who lived in overcrowded conditions in the year 2000. 48.5% (229.9 million) of people living in overcrowded conditions came from six African countries (Nigeria, Ethiopia, Democratic Republic of the Congo, Sudan, Uganda, and Kenya), with a combined population of 538.3 million people. Interpretation This study incorporated survey and population censuses data and used geostatistical modelling to estimate continent-wide overcrowding over a 19-year period. Our analysis identified countries and areas with high numbers of people living in overcrowded conditions, thereby providing a benchmark for policy planning and the implementation of interventions such as in infectious disease control. Copyright (c) 2022 The Author(s). Published by Elsevier Ltd.

3.
Embase; 27.
Preprint in English | EMBASE | ID: ppcovidwho-346615

ABSTRACT

Background: COVID-19 pandemic affected common disease infections, while the impact on hand, foot, and mouth disease (HFMD) is unclear. Google Trends data is beneficial in approximately real-time statistics and easily accessed, expecting to be used for infection explanation from information-seeking behavior perspectives. We aimed to explain HFMD cases before and during COVID-19 using Google Trends data. Method(s): HFMD cases were obtained from the National Institute of Infectious Disease, and Google search data from 2009 to 2021 was downloaded using Google Trends in Japan. Pearson correlation coefficients were calculated between HFMD cases and the search topic "HFMD" from 2009 to 2021. Japanese tweets containing "HFMD" were retrieved to select search terms for further analysis. Search terms were retained with counts larger than 1000 and belonging to ranges of infection sources, susceptible sites, susceptible populations, symptoms, treatment, preventive measures, and identified diseases. Cross-correlation analyses were conducted to detect lag changes between HFMD cases and HFMD search terms before and during COVID-19. Multiple linear regressions with backward elimination processing were used to identify the most significant terms for HFMD explanation. Result(s): HFMD cases and Google search volume peaked around July in most years without 2020 and 2021. The search topic "HFMD" presented strong correlations with HFMD cases except in 2020 when COVID-19 outbroke. In addition, differences in lags for 73 (72.3%) search terms were negative, might indicating increasing public awareness of HFMD infections during the COVID-19 pandemic. Results of multiple linear regression demonstrated that significant search terms contained the same meanings but expanded informative search content during COVID-19. Conclusion(s): Significant terms for HFMD cases explanation before and during COVID-19 were different. The awareness of HFMD infection in Japan may improve during the COVID-19 pandemic. Continuous monitoring is important to promote public health and prevent resurgence. Public interest reflected in information-seeking behavior can be helpful for public health surveillance. Copyright The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

4.
Pathog Glob Health ; : 1-9, 2022 Oct 19.
Article in English | MEDLINE | ID: covidwho-2077523

ABSTRACT

Air pollution may be involved in spreading dengue fever (DF) besides rainfalls and warmer temperatures. While particulate matter (PM), especially those with diameter of 10 µm (PM10) or 2.5 µm or less (PM25), and NO2 increase the risk of coronavirus 2 infection, their roles in triggering DF remain unclear. We explored if air pollution factors predict DF incidence in addition to the classic climate factors. Public databases and DF records of two southern cities in Taiwan were used in regression analyses. Month order, PM10 minimum, PM2.5 minimum, and precipitation days were retained in the enter mode model, and SO2 minimum, O3 maximum, and CO minimum were retained in the stepwise forward mode model in addition to month order, PM10 minimum, PM2.5 minimum, and precipitation days. While PM2.5 minimum showed a negative contribution to the monthly DF incidence, other variables showed the opposite effects. The sustain of month order, PM10 minimum, PM2.5 minimum, and precipitation days in both regression models confirms the role of classic climate factors and illustrates a potential biological role of the air pollutants in the life cycle of mosquito vectors and dengue virus and possibly human immune status. Future DF prevention should concern the contribution of air pollution besides the classic climate factors.

5.
Neuropsychological Trends ; - (31):43-54, 2022.
Article in English | Web of Science | ID: covidwho-2072137

ABSTRACT

Brain, the most powerful object in the universe, consumes only a few watts of energy. To replicate it, a nuclear power plant will be necessary, and this powerhouse is the sole controller of the human body. Normally, the brain is divided into two parts, with the left and right hemispheres working independently. The right half of the brain tends to cause mental tension and anxiety, exacerbating the present physiological condition like the current COVID-19 outbreak. A survey was done in the Durg district of Chhattisgarh, which is one of the hardest hit epicenters of the COVID-19 second wave in India. According to this survey, the majority of women of all ages are right brained, meaning their right hemisphere predominates over their left. They are more likely to suffer from mental illnesses than men because they are more inventive and creative thinkers. To avoid this circumstance, stress-relieving activities have been developed.

6.
2021 Ieee International Conference on Smart Computing (Smartcomp 2021) ; : 276-285, 2021.
Article in English | Web of Science | ID: covidwho-2070441

ABSTRACT

Identification of people with elevated body temperature can reduce or dramatically slow down the spread of infectious diseases like COVID-19. We present a novel fever-screening system, (FS)-S-3, that uses edge machine learning techniques to accurately measure core body temperatures of multiple individuals in a free-flow setting. (FS)-S-3 performs real-time sensor fusion of visual camera with thermal camera data streams to detect elevated body temperature, and it has several unique features: (a) visual and thermal streams represent very different modalities, and we dynamically associate semantically-equivalent regions across visual and thermal frames by using a new, dynamic alignment technique that analyzes content and context in real-time, (b) we track people through occlusions, identify the eye (inner canthus), forehead, face and head regions where possible, and provide an accurate temperature reading by using a prioritized refinement algorithm, and (c) we robustly detect elevated body temperature even in the presence of personal protective equipment like masks, or sunglasses or hats, all of which can be affected by hot weather and lead to spurious temperature readings. (FS)-S-3 has been deployed at over a dozen large commercial establishments, providing contact-less, free-flow, real-time fever screening for thousands of employees and customers in indoors and outdoor settings.

7.
Journal of Research in Medical and Dental Science ; 10(8):96-99, 2022.
Article in English | Web of Science | ID: covidwho-2067804

ABSTRACT

The spread of Covid 19 virus all over the globe in 2019 from Wuhan, China has posed possible threats to all the age groups of the human race. In the month of January dated 30 of the year 2020 the disease was declared as a public health emergency of International Concern and further them declared Corona virus illness as a pandemic on 11 March 2020. There had been numerous times when the virus has evolved into a new strain and many variants of the virus have emerged since the year 2021, and became dominant and spread too many countries, With the Delta, Alpha and Beta variants are the most virulent and Omicron being the latest strain of the virus. The virus posed threats in all possible forms from economic damages to the country to attacking the lives of people. The virus has all the potential of damaging organs severely. All the classes, strata's and age groups were affected, out of which the maximum to bear the brunt of the virus were the elderly and frail patients. They contracted infections easily and could not overcome the damage virus caused to the various organs. In this review, we will be discussing then the palliative care for elderly when there are times patients cannot be admitted in the hospital or are terminally ill and the condition doesn't seem to improve in spite of all the measure taken, we resort to improve their life and decreasing their pain and discomfort. Through this article we would be discussing about all the measure that can be taken to do the same.

8.
Int J Infect Dis ; 119: 24-31, 2022 Jun.
Article in English | MEDLINE | ID: covidwho-2069113

ABSTRACT

BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease with a high fatality rate. How the glucose level might affect the clinical outcome remains obscure. METHODS: A multicenter study was performed in 2 hospitals from 2011 to 2021. Patients with SFTS and acute hyperglycemia (admission fasting plasma glucose [FPG] ≥7 mmol/L), postadmission hyperglycemia (admission FPG <7 mmol/L but FPG ≥7 mmol/L after admission), and euglycemia (FPG <7 mmol/L throughout hospitalization) were compared for their clinical progress and outcomes. RESULTS: A total of 3225 patients were included in this study, 37.9% of whom developed acute hyperglycemia and 7.6% postadmission hyperglycemia. The presence of acute hyperglycemia, with or without known diabetes, was associated with increased risk of death (odds ratio [OR]: 1.63; 95% confidence interval [CI]: 1.29-2.05) compared with euglycemia. This effect, however, was only determined in female patients (OR: 2.15; 95% CI: 1.54-2.93). Insulin treatment of patients with SFTS and acute hyperglycemia without previous diabetes was associated with significantly increased mortality (OR: 1.58; 95% CI: 1.16-2.16). CONCLUSION: Acute hyperglycemia can act as a strong predictor of SFTS-related death in female patients. Insulin treatment of hyperglycemia in patients with SFTS without pre-existing diabetes has adverse effects.


Subject(s)
Diabetes Mellitus , Hyperglycemia , Insulins , Severe Fever with Thrombocytopenia Syndrome , Acute Disease , Blood Glucose , Female , Humans , Hyperglycemia/complications , Hyperglycemia/drug therapy
9.
Neurology Asia ; 27(3):783-786, 2022.
Article in English | EMBASE | ID: covidwho-2067763

ABSTRACT

Neutropenia during recovery after coronavirus disease 2019 (COVID-19), as well as neutropenia after intravenous immunoglobulin (IVIG) administration are very rare hematological abnormalities. We report the first case of agranulocytosis following IVIG administration in patients with Guillain-Barre syndrome (GBS) triggered by COVID-19. A 62-year-old female patient was admitted to the Emergency Department due to progressive limb weakness and sensory disturbances that began two weeks before admission. Five weeks before admission she was treated for COVID-19 and has fully recovered. She was diagnosed with Guillain-Barre syndrome (GBS), and treatment with IVIG was started. Twenty hours after the first dose of IVIG, blood analysis showed neutropenia and thrombocytopenia, and after the fifth dose she developed agranulocytosis followed by mild increase in body temperature. Granulocyte colony-stimulating factor (G-CSF) was administered and after 12 hours the leukocyte lineage recovered. According to the previous findings, neutropenia after IVIG administration might be related to CD11b, and COVID-19 is associated with an increase in immature neutrophil populations in the later stages of the disease defined by their expression of CD11b. Meanwhile, some finding suggests that corticosteroid pretreatment prevent neutropenia after IVIG administration, which might be important because many patients with post-COVID GBS have been treated with corticosteroids for COVID-19. Copyright © 2022, ASEAN Neurological Association. All rights reserved.

10.
Pakistan Journal of Medical and Health Sciences ; 16(8):88-91, 2022.
Article in English | EMBASE | ID: covidwho-2067739

ABSTRACT

Background: The COVID-19 first surfaced when cluster of pneumonia patients arose in Wuhan, Hubei Province, China. Although the current gold standard for COVID-19 diagnosis is reverse transcriptase-polymerase chain reaction (RT-PCR), chest x-ray (CXR) and computed tomography (CT) play a vital role in sickness diagnosis due to their limited sensitivity and availability. Aim: To evaluate retrospectively the role of CXR, the main radiological findings in it and its diagnostic accuracy in COVID-19 pneumonia. Methods: This is a cross sectional study involving 264 PCR positive COVID-19 patients with their clinical-epidemiological findings admitted at Ziauddin Hospital from May-July 2020. CXRs were taken as digital radiographs in our emergency department's isolation wards using the same portable X-ray device, according to local norms. CXRs were taken in two directions: antero-posterior (AP) and postero-anterior (PA). The hospitals' database had all of the images. To determine the number of radiological findings, multiple radiologists on duty completed an independent and retrospective examination of each CXR. In the event of disagreement, a mutual agreement was reached. SPSS version 20 was used for statistical analysis. Results: We were able to find 264 patients who met our criteria. With a mean age of 56.4214.89, the majority of individuals were determined to be males 189(71.6%) and females 75(28.4%). (Range of 16 to 87 years). 127 patients (48.1%) had severe illness symptoms and were admitted to the ICU, while the remaining 102(38.6%) had mild to moderate disease 35(13.3%). Diffuse (29.2%) and middle and lower co-existing distribution (25.8%) whereas just lower lobe (13.3%) were the most common predominance in severity. Peripheral involvement was also seen in (8.7%) cases. Conclusion: Both lungs are equally affected with the disease having the consolidation and opacifications while the effusion is the major complication in the severe cases. Diffuse involvement of the lung lobes is seen in the study followed by the middle and lower lobe involvement.

11.
Pakistan Journal of Medical and Health Sciences ; 16(8):24-26, 2022.
Article in English | EMBASE | ID: covidwho-2067738

ABSTRACT

Aim: To evaluate the potential use of ivermectin with standard therapy among mild to moderate covid-19 illness. Methods: This is a single-centered, prospective observational, randomized, parallel group (1:1 ratio), standard versus controlled ivermectin study recruited 210 confirmed COVID-19 positive patients who were admitted in COVID treatment center of Dr Ruth Kum Pafu Civil hospital Karachi, Pakistan from 1st November 2020 to 30th May 2021. Data were analyzed using SPSS version Results: Total of 210 patients were enrolled in the study and aged matched patients were divided in two groups 105 patients received ivermectin 6 mg twice a day for five days along with standard therapy while remaining 105 patients received standard therapy as per local and international guidelines. Male were 140(66.7%) and female 70(33.3%);age ranges between 26 to 77 years and majority 140( 66.7%) were more than 50 years of age. Fever, dry cough and dyspnea were the major symptoms seen;112(53.3%) patients had DM as a comorbid illness . Total of 21(20%) of 105 patients of ivermectin group had negative PCR for COVID 19 on day seven while the other group had positive covid test in all of 105 patients . On day 10 total of 49 more patients from ivermectin group found COVID negative along with 21 previously negative had second PCR was found negative in this way total of 70( 66.7%) of ivermectin group had negative PCR for COVID 19 while 21(20%) patients from non ivermectin got negative PCR for COVID 19 on day 10 . Conclusion: Use of ivermectin with standard therapy clear the virus earlier than standard therapy in mild to moderate COVID-19 infected patients admitted in COVID treatment center of Dr Ruth Kum Pafu Civil Hospital Karachi.

12.
Indian Journal of Forensic Medicine and Toxicology ; 16(3):78-83, 2022.
Article in English | EMBASE | ID: covidwho-2067689

ABSTRACT

Introduction: Vaccines are one of the most effective interventions for destroying COVID-19. Many organizations have worked to establish an efficient and safe preparation in the minimum time possible. Currently, several products that different in form and effectiveness are approved for sale. Objective(s): The goal of this study was to obtain evidence on COVID-19 vaccination adverse effects. Methodology: A cross-sectional study was made between October and December 2021 to obtain data on the influence of the COVID-19 vaccine among people in the Iraq-Basrah. There were two types of questions listed. The first one covers the subject's background information, such as nationality, gender, age, educational level, and past COVID 19 infection. The second set of questions focused on information about the COVID-19 vaccines and their side effects. Result(s): Local site adverse reaction, Hypersensitivity reaction, bone and muscle pain, headache and fever were more common in persons received second dose than in participant received first dose. There was a significant difference in the number of people those under 60 years of age who reported fever, headache, bone and muscle pain compared to those 60 years old and over. conclusion: The COVID-19 vaccine's side effects are similar to those seen with earlier immunizations, and the most of them are tolerable. Copyright © 2022, Institute of Medico-legal Publication. All rights reserved.

13.
Journal of Pure and Applied Microbiology ; 16(3):1622-1627, 2022.
Article in English | EMBASE | ID: covidwho-2067515

ABSTRACT

Methicillin-resistant Staphylococcus aureus (MRSA) infections are a primary health concern. They are commonly differentiated as hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) and community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections, based on their epidemiology, susceptibility findings, and molecular typing patterns. Therefore, appropriate contact precautions and isolation measures should be implemented. CA-MRSA mostly causes skin and soft-tissue infections, but the probability and incidence of it causing sepsis and invasive infections have increased dramatically in recent years. In this study, we report a case of CA-MRSA pneumonia with pan-pneumonic effusion in a 59-year-old male diabetic patient with preexisting comorbidities such as diabetic ketoacidosis and non-ST elevated myocardial infarction. The early reporting of the organism's identity and its antimicrobial susceptibility, as well as timely initiation of antibiotic therapy, aided in the successful management and cure of the patient.

14.
Iranian Journal of Neurology ; 19(4):122-130, 2020.
Article in English | EMBASE | ID: covidwho-2067436

ABSTRACT

Background: Few studies have reported the association of Guillain-Barre syndrome (GBS) and coronavirus disease-2019 (COVID-19) infection. In this study, we reported GBS in six patients infected with COVID-19 and reviewed all existing literature about GBS in association with COVID-19. Method(s): This study was performed in three referral centers of COVID-19 in Iran, and six patients with the diagnosis of GBS were enrolled. Patients enrolled in the study with acute progressive weakness according to the demyelinating or axonal variant of GBS, according to Uncini's criteria. Result(s): Four of our patients had axonal polyneuropathy, two patients had demyelinating polyneuropathy, and one patient required mechanical ventilation. All our patients had a favorable response to treatment. In one patient, the GBS symptoms recurred four months after the first episode. Conclusion(s): Limited case reports suggest a possible association between GBS and COVID-19. Such associations may be an incidental concurrence or a real cause-and-effect linkage;however, more patients with epidemiological studies are necessary to support a causal relationship. Copyright © 2020 Iranian Neurological Association, and Tehran University of Medical Sciences.

15.
Iatreia ; 35(4):414-423, 2022.
Article in Spanish | EMBASE | ID: covidwho-2067412

ABSTRACT

Objective: To identify the clinical presentation and factors associated with anosmia and ageusia in patients with COVID-19 in a health center in a province of Peru for the period 2020-2021. Method(s): Cross-sectional analytical study through data from the COVID-19 program of the Essalud Po-lyclinic in Jauja, Peru. Sociodemographic characte-ristics, symptoms and comorbidities of the patients were detailed. A bivariate analysis identified the factors associated with anosmia and ageusia. Result(s): 356 patients were identified: 53.1 % were wo-men, mean age was 48.7 years (+/-17.8) and 261 (73.3%) with mild COVID-19. Of the total, 22.2% had anosmia and 19.9% ageusia;of which the majority were un-der 65 and female. Associated symptoms were found in 86.1% of patients with anosmia and 83.1% with ageusia. The main factors associated with anosmia were age younger than 65 years (p=0.027), cough (p<0.001), headache (p<0.001), dyspnea (p<0.001), nasal congestion (p<0.001) and fever (p<0.001);and ageusia: age younger than 65 years (p=0.006), cough (p=0.001), headache (p<0.001), dyspnea (p<0.001), nasal congestion (p<0.001) and diarrhea (p<0.001). Conclusion(s): Anosmia and ageusia are common symptoms of COVID-19. Most patients had these symptoms associated with common symptoms. Many of those who had anosmia had nasal congestion, so it is advisable to consider differentiating them when making the diagnosis. Copyright © 2022, Universidad de Antioquia. All rights reserved.

16.
Pediatricheskaya Farmakologiya ; 19(2):196-200, 2022.
Article in Russian | EMBASE | ID: covidwho-2067387

ABSTRACT

Background. Students, as the most active and mobile part of population, often unite into educational and informal groups, move to other regions or countries, and present a specific risk group for the spread of new coronavirus infection. Thus, they require preventive vaccination. objective. the aim of the study is to study the immunological potency, tolerance, and efficacy of GamCOVID-Vac vaccine among students of Krasnodar. methods. 119 seronegative students (18–30 years old) were examined. SARSCoV-2 IgG (ELISA method) was determined 1, 3, and 6 months after two completed rounds of vaccination. Post-vaccination adverse events and COVID-19 cases were evaluated in the study. results. SARS-CoV-2 IgG level 1 month after vaccination ranged from 6.15 to 19.38 and was to 16.39 (AU/mL) ± 1,12. Immunological potency values ranged from 4.407 to 21.5 (AU/mL) (14.74 ± 2.93) 3 months after. IgG titers were in the range of 4.14 to 17.71 (AU/mL) (10.97 ± 4.69) 6 months after. Adverse events after vaccination were revealed in 34 respondents (28.6%). Among them, local (hyperemia, pain, edema) — 21 (17.6%): slight — 90.4%, major — 9.6%;general (fever, weakness, algor, headache, arthralgia, myalgia) — 13 (10.9%): slight — 69.2%, major — 30.8%. The increase in vaccination coverage in students from 30.3 to 79.1% reduced the COVID-19 morbidity from 3.81 to 1.57%. conclusion. Gam-COVID-Vac vaccine induced stable humoral response, demonstrated sufficient safety, and reduced morbidity 2.4-fold.

17.
Pediatricheskaya Farmakologiya ; 19(1):78-81, 2022.
Article in Russian | EMBASE | ID: covidwho-2067385

ABSTRACT

Background. The morbidity of new coronavirus infection remains high (in children as well). Children with bronchial asthma are not at risk this disease development and severe course of COVID-19 according to the previous studies results. Objective. The aim of the study is to compare the morbidity rate of COVID-19 among children with and without bronchial asthma between May 2020 and October 2021 with the results from the beginning of pandemics. Methods. Online questionnaires in Google form have been developed and sent to parents of 83 patients aged from 7 to 17 years who have been interviewed at the beginning of the pandemics. The main group includes 49 patients diagnosed with bronchial asthma, and the control group includes 25 children without bronchial asthma. Results. 45% (22) of patients had COVID-19 in the main group and 32% (8) — in the control group (p = 0.636). 80% of patients had mild course of disease and 20% — moderate in the main group, and 62% and 37% in the control group respectively. Febrile fever was observed in 40% of respondents in the main group and in 33% — in the control group;anosmia — in 35% in the main and in 14% — in the control group;pulse oximetry was used by 44% of patients in the main group (SpO2 94–98%) and 42% in the control group (SpO2 98–99%);66% of patients had baseline therapy and 6% had rescue medications in the main group. No one from both groups has been hospitalized. Conclusion. Pediatric patients both with and without bronchial asthma have COVID-19 more often compared to the pandemics beginning. The disease in most cases had mild course and did not require hospitalization, aggravations of bronchial asthma were rare and saturation values did not decrease below 94%.

18.
NeuroQuantology ; 20(10):6860-6870, 2022.
Article in English | EMBASE | ID: covidwho-2067308

ABSTRACT

The year 2019 is a outbreak year during which the whole globe has suffered from Covid19 pandemic which has been spotted initially in China and later spread to the whole world;as a result of this viral disease, the whole world had shut down affecting billions of people but till today the Covid battle is on and people are suffering not only from this disease but also in terms of economy, starving being jobless etc. This paper briefs about Corona virus, its types, and structure;the replication and spreading of this virus, Covid19 detection methods, research on vaccination developed across the world to curb this virus;virus impact on various sectors, precautions to be taken to stay away from this virus and Ayurvedic remedy for it. The waves of corona had taken many lives on the globe & have its effect on life style of people. To curb this virus, prevention vaccination has to be found and we people must change in a way so that we could avoid future consequences for the upcoming generation. Keywords.

19.
Oto-Rhino-Laryngology Tokyo ; 64(3):145-149, 2021.
Article in Japanese | EMBASE | ID: covidwho-2067222

ABSTRACT

Reverse -transcription polymerase chain reaction (RT-PCR)testing is necessary for the definitive diagnosis of coronavirus disease 2019(COVID-19), and is most often performed on pharyngeal swabs. However, it has become clear that even if the RT-PCR is negative, COVID-19 cannot be ruled out altogether. We encountered a patient who developed COVID-19 after a tracheostomy. He developed fever and respiratory failure and was suspected as having developed COVID-19, but RT-PCR conducted on upper airway specimens was negative twice in succession;a third RT-PCR test conducted on a sputum specimen later confirmed a positive result for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). In cases with clinically suspected infection with SARS-CoV-2, RT-PCR should be repeated, and lower respiratory tract specimens should be used from the beginning if the infection occurs before or after tracheostomy. Copyright © 2021 Society of Oto-Rhino-Laryngology Tokyo. All rights reserved.

20.
Journal of Clinical and Diagnostic Research ; 16(9):KD01-KD03, 2022.
Article in English | EMBASE | ID: covidwho-2067200

ABSTRACT

Being a highly contagious disease, Coronavirus Disease-2019 (COVID-19) has shown its impact throughout the world. Clinical manifestations are seen primarily involving the respiratory system. Fever, cough, fatigue, and breathlessness are the commonly seen symptoms. Several cases of COVID-19 manifest as viral pneumonia-induced Acute Respiratory Distress Syndrome (ARDS). COVID-19 symptoms appear not only during the course of the illness but also as its after effects. Long COVID-19 is said to be multisystem syndrome, categorised as postacute or chronic depending upon the time frame. It is characterized by the presence of symptoms beyond four weeks of the actual disease. Change in structural components in the lung leads to having a functional consequence on the body, affecting the cognitive, psychosocial, mental and physical well-being of the patients. Studies have shown alveolar damage same as ARDS. The most common pulmonary sequences seen are dyspnoea, cough (dry/with expectoration) and decreased diffusion capacity leading to reduced endurance. The present case report was of a 45-year-old nurse, who presented with the symptoms of postacute long COVID-19. Her previous scan of thorax showed a severity score of 11/25 after being tested COVID-19 positive. In view of the presenting complaints, a tailor-made pulmonary rehabilitation program was administered which showed great improvement in overall health condition. This case had been reported to document the effects of post COVID rehabilitation program on aspects such as functional capacity, quality of life, anxiety and depression using novel measures such as Incremental Shuttle Walk Test (ISWT), World Health Organisation Quality of Life-Brief Version (WHOQOL-BREF), and Depression, Anxiety and Stress Scale - 21 Items (DASS-21). Rehabilitation has been proven to be effective and safe in improving the exercise performance, quality of life affected due to COVID-19 and psychological function of the patients. Copyright © 2022 Journal of Clinical and Diagnostic Research. All rights reserved.

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