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1.
Int J Legal Med ; 2022 Oct 27.
Article in English | MEDLINE | ID: covidwho-2085366

ABSTRACT

We report a case of cerebral venous sinus thrombosis, bilateral adrenal hemorrhage, and thrombocytopenia in a 70-year-old man found dead. He had previously received the ChAdOx1 nCoV-19 vaccine (Vaxzevria®, AstraZeneca) 18 days before, and had since developed unspecific and undiagnosed characteristics of what proved to be a rare case of vaccine-associated thrombocytopenia with thrombosis syndrome (TTS). He was found dead 1 week after the beginning of symptoms (day 25 post-vaccine). Autopsy yielded venous hemorrhagic infarction with the presence of thrombi within dural venous sinuses, and extensive hemorrhagic necrosis of the central part of the adrenal glands. Antibodies against platelet factor 4 (PF4) were strongly positive in postmortem fluids, as measured with an enzyme-linked immunosorbent assay (ELISA). This difficult diagnosis is usually made during the patient's lifetime. After eliminating differential diagnoses, we concluded on a fatal case of vaccine-induced immune TTS with positive anti-PF4 antibodies in cadaveric blood, 3 weeks after ChAdOx1 nCoV-19 vaccination. Specific search for anti-PF4 antibodies in cadaveric blood appears therefore paramount to assess postmortem cases of TTS associated with anti-COVID vaccines.

2.
Romanian Journal of Legal Medicine ; 30(1):8-11, 2022.
Article in English | EMBASE | ID: covidwho-2066935

ABSTRACT

Objectives. The present research is a longitudinal study with the aim of highlighting the effect of the pandemic on the frequency of aggressions from a forensic perspective. The hypothesis started from the premise that the aggressions showed an increasing trend during the pandemic, indicating a significant difference between the number of aggressions in the previous period and the number of aggressions in the pandemic and post-pandemic period. Population. The sample of the study consisted of 420 people who were identified by forensic findings at the Institute of Forensic Medicine of Cluj Napoca, as victims of aggression between 2019-2022. The results showed significant differences in the number of aggressions during the pandemic period resulting in an upward trend. Conclusions. The pandemic period had a significant impact on aggressive behaviors, with a tendency of an increased number of aggressions.

3.
Med Sci Law ; : 258024221125135, 2022 Sep 09.
Article in English | MEDLINE | ID: covidwho-2020721

ABSTRACT

The International Criminal Court has recently opened an investigation into the international crimes committed on Ukrainian territory. The ongoing Russian-Ukrainian war is a tragic opportunity for a necessary critical and scientific reading of the Rome Statute. In our work, we aim to critically analyse the contents of the International Criminal Court's Rome Statute, with particular attention to the definition and listing of war crimes. Our objective is to assess whether the content of the Rome Statute and the Geneva Convention is useful to provide a correct and complete orientation of the medico-legal work in the context of war. We believe, in fact, that the forensic pathologists, and forensic experts in general, are the only professional figures specialised in providing scientific evidence of crimes compatible with war crimes. Their timely intervention and the standardisation of their work - in association with a review of the deficient content found in the Rome Statute - is essential in order to allow the prosecution of international crimes, already potentially undermined by the slowdowns associated with the COVID-19 pandemic that is the backdrop to the current conflict.

4.
Journal of Forensic Medicine and Toxicology ; 39(1):1-4, 2022.
Article in English | EMBASE | ID: covidwho-2006462
5.
Journal of Forensic Medicine and Toxicology ; 39(1):51-55, 2022.
Article in English | EMBASE | ID: covidwho-1988392

ABSTRACT

Background: Since December 2019, a novel coronavirus disease (COVID-19) began its journey around the world. Since then, many efforts are being carried out to contain the virus. Knowledge and attitude of people should be directed towards strict preventive practices in order to halt the spread of the virus. Medical students, as frontline healthcare workers, are more susceptible to be infected by the virus. The aim of the current cross-sectional study is to assess the knowledge, practice and attitude of 2nd year medical students from medical college in tribal part of Gujarat, India, regarding dead body management of covid-19 patients. Methods: A self-designed questionnaire consisting of 19 questions was developed and given to the students. The knowledge, attitude, and practice of the participants were investigated. Results: A total of 235 medical students completed the questionnaire. Out of the total participants (n=235), 133(56.6%) were male and 102(43.4%) were female. 88.9% of students knew the fact that covid-19 dead body is infective, 94.5% students are aware about specific guidelines for dead body management of covid-19 patients, 40% students have no knowledge about Medico-legal Autopsy of COVID 19 case will be conducted strictly by avoiding any invasive surgical procedures. Conclusion: We found a high level of COVID-19 related knowledge and self-reported preventive behaviors and moderate risk perception among 2nd year medical students, which is easily available on social media, internet and printed media. But they are very poor in specific knowledge which is given in Dead body management guidelines.

6.
Rev. bioét. (Impr.) ; 30(2): 346-354, abr.-jun. 2022. tab
Article in Portuguese | WHO COVID, LILACS (Americas) | ID: covidwho-1951698

ABSTRACT

Resumo Conhecer o paradigma ético que fundamenta o código moral da medicina é fundamental para atuar não só na assistência, mas também em processo pericial. A partir de revisão da literatura, propõe-se avaliar a maneira como os quatro princípios éticos fundamentais (beneficência, não maleficência, autonomia e justiça) se aplicam antes, durante e após a perícia psiquiátrica, como perito ou como assistente técnico. Novos desafios éticos vêm surgindo na psiquiatria forense. Com a pandemia de covid-19, a tecnologia foi adotada para permitir a prática da telemedicina, mas ainda se debate se seria suficiente para promover avaliação pericial psiquiátrica adequada. Considerando a complexidade da área, cada situação deve ser analisada de forma individual e abrangente, sendo recomendável buscar auxílio para debater as perspectivas éticas e legais das perícias psiquiátricas quando necessário.


Abstract Knowing the ethical paradigm that bases the medicine moral code is fundamental to act not only in care but also in the expert testimony process. From a revision of the literature, we propose to evaluate the way the four fundamental ethical principles (beneficence, nonmaleficence, autonomy, and justice) apply before, during, and after the psychiatric expert testimony, be it as expert or as technical assistant. New ethical challenges have been appearing in forensic psychiatry. With the COVID-19 pandemic, technology was adopted to allow the practice of telemedicine, but debates still occur if that would suffice for an adequate psychiatric expert testimony evaluation. Considering the complexity of the area, each situation must be analyzed in an individualized and all-encompassing way and seeking help to debate the ethical and legal perspectives of psychiatric expert testimonies is recommended when necessary.


Resumen Conocer el paradigma ético que subyace en el código moral de la medicina es fundamental para actuar no solo en la asistencia, sino también en el proceso pericial. A partir de una revisión bibliográfica, se propone evaluar cómo se aplican los cuatro principios éticos fundamentales (beneficencia, no maleficencia, autonomía y justicia) antes, durante y después de la pericia psiquiátrica, ya sea como perito o como asistente técnico. Están surgiendo nuevos desafíos éticos en la psiquiatría forense. Con la pandemia del Covid-19, se utilizó la tecnología para permitir la práctica de la telemedicina, pero aún está en debate si esto es suficiente para promover una adecuada evaluación psiquiátrica forense. Considerando la complejidad del área, se debe analizar cada situación de manera individual e integral y, cuando sea necesario, buscar ayuda para debatir las perspectivas éticas y legales de la pericia psiquiátrica.


Subject(s)
Forensic Psychiatry , Ethical Theory , Ethics , Expert Testimony , Forensic Medicine , Morals
7.
Clinical Toxicology ; 60(SUPPL 1):1, 2022.
Article in English | EMBASE | ID: covidwho-1915439

ABSTRACT

Objective: In response to the evolving threat of illicit drug use, combined with anticipated SARS-CoV-2 (COVID-19) pandemicrelated market volatility, we created a multi-institution network supplying high-quality data on illicit drug presentations to Victorian emergency departments (EDs). Primary objective: timely data provision to a state Early Warning System (EWS) utilising multiple intelligence sources (including syringe residue and wastewater analysis) to inform public health interventions. Methods: The Emerging Drugs Network of Australia VIC (EDNAV) project is a multi-site prospective observational study collating de-identified clinical and analytical information within an electronic clinical registry (Research Electronic Data Capture secure web-based software platform). Case inclusion criteria: individuals ≥16 years of age presenting with suspected illicit drug toxicity requiring venepuncture as part of standard care. Hospital ethics committee approved waiver of patient consent for inclusion of deidentified data. Nine metropolitan and one regional ED contributed blood samples for weekly toxicological analysis at the Victorian Institute of Forensic Medicine. Liquid chromatographytandem mass spectrometry (LC-MS/MS) screened for 327 pharmaceuticals and illicit substances, as well as 268 novel psychoactive substances. EDNAV data was reviewed weekly as a component of the state EWS. High-risk signals were disseminated to government and external stakeholders. Results: During September 2020 - March 2021, 320 cases were analysed (70% male, mean age 30 years, 72% ambulance arrival). Sedation (Glasgow Coma Score (GCS)<9, 35%) and agitation (33%) were the commonest reasons for presentation;33% of patients required parenteral sedation, and 18% were administered naloxone. In addition, 8% were intubated and 11% required critical care admission;85% had a Poisoning Severity Score of ≥2. There were two deaths. There were 815 separate detections (345 illicit substances, 470 pharmaceuticals). At least one illicit drug was detected in 87% of cases (> 1 illicit drug in 43%). Common illicit drugs included methylamphetamine (52% of cases), gamma-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA), cocaine and opioids. Eight novel benzodiazepines, 7 cathinones, 5 hallucinogens, 3 synthetic cannabinoid receptor agonists (SCRAs) and one novel opioid (Beta-U10) were detected. In 90% of cases, reported exposure differed from analytical findings. During COVID-19 related lockdowns, there was evidence of substance substitution including benzodiazepines in products sold as heroin. Three public health warnings were released in association with EDNAV findings (Nethylpentylone in cocaine, 25B-NBOH sold as lysergic acid diethylamide (LSD), paramethoxymethamphetamine (PMMA) sold as MDMA). Conclusion: For the first time in Victoria, a network of healthcare institutions working together enabled timely detection of illicit drug related harm, facilitating early public health warnings and notification of peer-based harm reduction services.

8.
PLoS Global Public Health ; 2(4), 2022.
Article in English | CAB Abstracts | ID: covidwho-1854952

ABSTRACT

The purpose of this article is to quantify the amount of misclassification of the Coronavirus Disease-2019 (COVID-19) mortality occurring in hospitals and other health facilities in selected cities in Brazil, discuss potential factors contributing to this misclassification, and consider the implications for vital statistics. Hospital deaths assigned to causes classified as garbage code (GC) COVID-related cases (severe acute respiratory syndrome, pneumonia unspecified, sepsis, respiratory failure and ill-defined causes) were selected in three Brazilian state capitals. Data from medical charts and forensic reports were extracted from standard forms and analyzed by study physicians who re-assigned the underlying cause based on standardized criteria. Descriptive statistical analysis was performed and the potential impact in vital statistics in the country was also evaluated. Among 1,365 investigated deaths due to GC-COVID-related causes, COVID-19 was detected in 17.3% in the age group 0-59 years and 25.5% deaths in 60 years and over. These GCs rose substantially in 2020 in the country and were responsible for 211,611 registered deaths. Applying observed proportions by age, location and specific GC-COVID-related cause to national data, there would be an increase of 37,163 cases in the total of COVID-19 deaths, higher in the elderly. In conclusion, important undercount of deaths from COVID-19 among GC-COVID-related causes was detected in three selected capitals of Brazil. After extrapolating the study results for national GC-COVID-related deaths we infer that the burden of COVID-19 disease in Brazil in official vital statistics was probably under estimated by at least 18% in the country in 2020.

9.
Curr Med Res Opin ; 38(5): 785-792, 2022 05.
Article in English | MEDLINE | ID: covidwho-1730405

ABSTRACT

OBJECTIVE: Examination of postmortem findings can help establish effective therapeutic strategies to reduce mortality. The aim of this study was therefore to review complete autopsy cases and their postmortem findings and comorbidities associated with death caused by COVID-19, in order to establish a profile of the deceased and the likelihood of time to death. METHODS: A systematic review was carried out following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and meets Cochrane criteria recommendations (PROSPERO registration number CRD 42020209649). An electronic search in the databases Pubmed, Scopus, Web of Science, Wiley Online Library, and Scientific Electronic Library Online (SciELO) was performed. RESULTS: The search strategy yielded a total of 25 articles where 140 cases of complete autopsies were reported. The most prevalent comorbidity was vascular diseases. Patients with vascular disease, heart disease, and diabetes died significantly in a shorter period of time. Autopsies mainly focused on the lungs. The proliferative phase of Diffuse Alveolar Damage (DAD) was the most reported in the microscopic postmortem findings, and these patients died in a shorter period of time. However, individuals aged over 80 years significantly presented fibrotic phase of DAD at the time of death. The kidney was the second most affected organ with thrombosis and tubular damage, followed by the liver with congestion and necrosis. CONCLUSION: Given that accurate information of complete autopsies findings is still scarce, it is necessary to perform complete autopsies by examining organs other than the lungs in order to provide information to improve new treatment strategies in patients with a high risk of mortality.


Subject(s)
COVID-19 , Vascular Diseases , Aged , Autopsy , Comorbidity , Humans , Lung , SARS-CoV-2
10.
Journal of Forensic Medicine Science and Law ; 30(2):71-75, 2021.
Article in English | Scopus | ID: covidwho-1695656

ABSTRACT

The XXIII Annual State conference of Medicolegal Association of Maharashtra (MLAM)-FORENSICON 2020 was hosted virtually by the Department of Forensic Medicine & Toxicology, T.N.M.C. & B.Y.L. Nair Ch. Hospital, Mumbai as a part of the Centenary year celebrations of the Institute on 10th and 11th April 2021. The intent of the conference was to educate and stimulate the postgraduates and faculty regarding newer pursuits in the field of Forensic Medicine. More than 500 delegates attended the conference, which included experts from the field as well as clinical practitioner’s and medical officers who were inclined towards Forensic Medicine. The e-release of the souvenir & MLAM Official Journal-Journal of Forensic Medicine, Science & Law was done at the same time. Sessions were conducted by dividing the lectures into Ante-mortem, Post-mortem and Academics. Engrossing topics were chosen which were delivered by established experts of that field. On day two of the conference, oral and poster presentations were done by faculty, postgraduate students and undergraduate students. © 2021, Medicolegal Association of Maharashtra. All rights reserved.

11.
IEEE Trans Med Robot Bionics ; 4(1): 94-105, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-1685153

ABSTRACT

In pathology and legal medicine, the histopathological and microbiological analysis of tissue samples from infected deceased is a valuable information for developing treatment strategies during a pandemic such as COVID-19. However, a conventional autopsy carries the risk of disease transmission and may be rejected by relatives. We propose minimally invasive biopsy with robot assistance under CT guidance to minimize the risk of disease transmission during tissue sampling and to improve accuracy. A flexible robotic system for biopsy sampling is presented, which is applied to human corpses placed inside protective body bags. An automatic planning and decision system estimates optimal insertion point. Heat maps projected onto the segmented skin visualize the distance and angle of insertions and estimate the minimum cost of a puncture while avoiding bone collisions. Further, we test multiple insertion paths concerning feasibility and collisions. A custom end effector is designed for inserting needles and extracting tissue samples under robotic guidance. Our robotic post-mortem biopsy (RPMB) system is evaluated in a study during the COVID-19 pandemic on 20 corpses and 10 tissue targets, 5 of them being infected with SARS-CoV-2. The mean planning time including robot path planning is 5.72±167s. Mean needle placement accuracy is 7.19± 422mm.

12.
Forensic Sci Med Pathol ; 18(2): 165-169, 2022 06.
Article in English | MEDLINE | ID: covidwho-1681799

ABSTRACT

Emerging evidence suggests that an onset or escalation of interpersonal violence has been occurring during the COVID-19 pandemic, particularly among persons in intimate or familial relationships. Strangulation (or neck compression) is a common form of interpersonal violence and can result in serious adverse health outcomes, including death. The identification and attribution of injuries from non-fatal strangulation are complex, as there may be an absence of external signs of injury and their appearance may be delayed by many days. There is a heavy reliance on clinician identification of 'red flag' symptoms and signs, the presence of which necessitates urgent further assessment. Additional challenges arise when acute non-fatal strangulation symptoms and signs are shared with other clinical conditions. In such cases, differentiating between the conditions based on the symptoms and signs alone is problematic. We present the diagnostic challenges faced when conducting forensic assessments of COVID-19-positive and suspected COVID-19 (S/COVID) patients following allegations of non-fatal strangulation in the setting of physical and sexual assaults. The implications of shared symptoms and signs, for forensic clinicians, primary healthcare, and emergency practitioners, as well as other frontline service providers, are discussed.


Subject(s)
COVID-19 , Sex Offenses , Asphyxia/diagnosis , Forensic Medicine , Humans , Pandemics
13.
Healthcare (Basel) ; 10(2)2022 Jan 29.
Article in English | MEDLINE | ID: covidwho-1667117

ABSTRACT

Forensic medicine has always held the human environment, either seen as a source for pathological agents or the background of judicial events, in great consideration. The concept of the environment has evolved through time, expanding itself to include all the physical and virtual sub-spaces in which we exist. We can nowadays talk of technoenvironmental reality; virtual spaces exploded because of the COVID-19 pandemic making us come to terms with the fact that those are the places where we work, where we socialize and, even, where we meet our doctors and can be cured. Artificial Intelligence (AI) has contributed to shaping new virtual realities that have got their own rules yet to be discovered, carved and respected. We already fight a daily battle to save our natural environment: along with the danger of green crimes, comes the need for environmental justice and environmental forensic medicine that will probably develop a forensic branch and an experimental branch, to implement our technical culture leading to definition of the real dimension of the risk itself to improve the role of legal medicine in the Environmental Risk Management. While green criminology addresses widespread green crimes, a virtual environment criminology will also develop, maybe with a contribution of AI in the justice field. For a sustainable life, the environmental revolution must rapidly take place, and there is the need for a new justice, a new forensic medicine and a new criminology too.

14.
Forensic Sci Med Pathol ; 18(2): 125-132, 2022 06.
Article in English | MEDLINE | ID: covidwho-1653767

ABSTRACT

To explore if the shutdown of Danish nightlife during the Covid-19 pandemic caused a decrease in the number of clinical forensic examinations of victims of sexual assault in Eastern Denmark. Secondarily, to investigate, if there was a change in criminological characteristics, e.g. scene and time of crime, relation to the perpetrator and the proportion of possible drug-facilitated sexual assaults. 130 case files from clinical forensic examinations of individuals of alleged sexual assault in the period 1st of April to 30th of June in both 2019 and 2020 were included. 67 and 63 examinations were performed in 2019 and 2020, respectively. 125 cases were female and five were male. Approximately 70% were 15-25 years of age. Pre- and post-lockdown victim profiles were similar regarding assailant relation, location of crime and time of assault. Voluntary intake of alcohol prior to the assault was registered with 46.3% in 2019 and 62% in 2020. The ratio of possible drug-facilitated sexual assault (DFSA) was approximately 50% each year. The lockdown did not seem to change the overall number of examinations or the demographic and criminological characteristics of the sexual assault victims. No decrease in cases of possible DFSA was found despite the lockdown of nightlife venues.


Subject(s)
COVID-19 , Crime Victims , Sex Offenses , Communicable Disease Control , Denmark/epidemiology , Female , Humans , Male , Pandemics , Retrospective Studies
15.
Current Directions in Biomedical Engineering ; 7(2):779-782, 2021.
Article in English | Scopus | ID: covidwho-1604996

ABSTRACT

Understanding the underlying pathology in different tissues and organs is crucial when fighting pandemics like COVID-19. During conventional autopsy, large tissue sample sets of multiple organs can be collected from cadavers. However, direct contact with an infectious corpse is associated with the risk of disease transmission and relatives of the deceased might object to a conventional autopsy. To overcome these drawbacks, we consider minimally invasive autopsies with robotic needle placement as a practical alternative. One challenge in needle based biopsies is avoidance of dense obstacles, including bones or embedded medical devices such as pacemakers. We demonstrate an approach for automated planning and visualising suitable needle insertion points based on computed tomography (CT) scans. Needle paths are modeled by a line between insertion and target point and needle insertion path occlusion from obstacles is determined by using central projections from the biopsy target to the surface of the skin. We project the maximum and minimum CT attenuation, insertion depth, and standard deviation of CT attenuation along the needle path and create two-dimensional intensity-maps projected on the skin. A cost function considering these metrics is introduced and minimized to find an optimal biopsy needle path. Furthermore, we disregard insertion points without sufficient room for needle placement. For visualisation, we display the color-coded cost function so that suitable points for needle insertion become visible. We evaluate our system on 10 post mortem CTs with six biopsy targets in abdomen and thorax annotated by medical experts. For all patients and targets an optimal insertion path is found. The mean distance to the target ranges from (49.9 ± 12.9)mm for the spleen to (90.1 ± 25.8)mm for the pancreas. © 2021 by Walter de Gruyter Berlin/Boston.

16.
European Neuropsychopharmacology ; 53:S419, 2021.
Article in English | EMBASE | ID: covidwho-1592736

ABSTRACT

Background. Notwithstanding predictions of increase in suicide risk related to the current pandemic [1,2], as was the case in previous pandemics [3], so far there is no clear evidence of increased rates of suicide, self-harm, suicide attempts, or suicidal thoughts associated with the COVID-19 pandemic [4]. An increase in suicide deaths after the initial decline in the pandemic ourbreak has been described in Japan [5]. Objective. We assessed the impact of the COVID-19 outbreak on trends in suicide mortality and suicidal behavior (SB) in Cantabria (Spain). Methods. Data collection: suicide mortalities by the Institute of Forensic Medicine of Cantabria (IML) and SB (suicidal ideation, or suicide attempt defined as any self-injurious act with at least some intent to die) by Emergency Department (ED) visits using triage data from the electronic health care records of University Hospital Valdecilla (HUMV, reference hospital for all psychiatric emergencies in Cantabria, Spain). Collection period: January-2015 to December-2020. Data are analyzed in three different COVID-19 pandemic periods (outbreak and lockdown: March–June;return to quasi-normality and second wave: July-September;third wave: October-December) compared to those same quarters of the previous five years. Since we exclusively used available aggregate data in this study, formal ethical review was not required. Results. Since 2015, there has been an increasing trend of admissions to the ED of HUMV for SB, having almost tripled between 2015-2019 (88 vs 249). During 2020, visits for SB decreased by more than 30% in comparison with the previous year (173 vs 249). This decline started in March with the onset of the covid-19 pandemic. Previously in the first quarter of the year there were 35% more consultations for SB than 2019. On the contrary, during lockdown (second quarter) SB visits were one third of those in the same period of 2019. Although the third and fourth quarters of 2020 see a doubling of visits compared to the containment period, the number of visits in both quarters is between 60-65% of those in 2019. In 2020, suicides have dropped compared to 2019, both in absolute numbers (46 vs. 52) and rates per-100,000 inhabitants (7.89 vs. 8.95). In the first quarter of 2020 there were 19 suicides (7 more versus 2019), but during lockdown there were only 8 (12 less than in the same period 2019). Conclusions. In Cantabria (Spain), no increase in suicide or SB has been observed related to the pandemic. Conversely, in 2020 we found a decrease in both, consultations for SB and deaths by suicide, compared to 2019. The decrease in suicides and SB has been observed in all periods of Covid-19 pandemic (outbreak and lockdown;quasi-normality and second wave;third wave). Suicide data are difficult to collect in real time and the economic effects of the pandemic are still evolving. Preventive strategies will need to be developed to cope the possible increase in suicide and SB when current social protective measures are discontinued.No conflict of interest

17.
Pathologe ; 42(Suppl 2): 129-134, 2021 Dec.
Article in German | MEDLINE | ID: covidwho-1491093

ABSTRACT

BACKGROUND: Autopsies are an important tool for understanding novel diseases, including COVID-19. MATERIALS AND METHODS: The German Registry of COVID-19 Autopsies (DeRegCOVID) was established and launched in April 2020. DeRegCOVID acts as the electronic backbone of the German Network for Autopsies in Pandemics (DEFEAT PANDEMIcs), which started in September 2020. RESULTS: The results of DeRegCOVID and DEFEAT PANDEMIcs are characterized by an unprecedented collaboration of more than 35 university and non-university autopsy centers linking pathological, neuropathological, and forensic medicine institutes. DeRegCOVID has evolved, adapted to new challenges, and currently contains the largest international autopsy dataset. After only a short period of operation, more than 80 publications have been produced, which have contributed to the understanding of the pathogenesis of COVID-19, e.g., through the discovery of thromboembolic events, multiorgan tropism, and NeuroCovid-19. The autopsy centers have carried out extensive educational work and, beyond the scientific gain in knowledge, have explained to politicians and the general public the essential role of autopsies in pandemic management. To further develop autopsy-driven research, a continuation of DEFEAT PANDEMIcs was conceived, the National Autopsy Network (NATON). CONCLUSIONS: The registry and network, in which all interested centers can participate, have demonstrated the value of networked medical research and the high value of autopsy for medicine.


Subject(s)
COVID-19 , Autopsy , Forensic Medicine , Humans , Pandemics , SARS-CoV-2
18.
Fa Yi Xue Za Zhi ; 37(4): 527-532, 2021 Aug.
Article in Chinese | MEDLINE | ID: covidwho-1481208

ABSTRACT

ABSTRACT: Abstract: Objective To analyze the first epidemic spread of the novel coronavirus Delta variant in China based on public security forensic perspective, investigate its transmission characteristics, contributing factors, and epidemiologic research experience, and provide a reference for the prevention and control of the epidemic caused by the novel coronavirus variant. Methods Based on the information that public security forensic experts obtained from front-line epidemiologic research, the gender, age, place of residence, transmission route and infectivity of the coronavirus disease 2019 (COVID-19) confirmed cases, asymptomatic infected persons and their close contacts in Guangzhou caused by the novel coronavirus Delta variant were analyzed. The basic reproduction number (R0) during this epidemic in Guangzhou was calculated. Results Among the 153 cases infected with novel coronavirus Delta variant in the epidemic, 63 cases were male and 90 cases were female, their age ranging from 1 to 92 years, with a median age of 49 years. The main route of transmission was close contact, including dining together, co-living, and close contact in the same residential building. There were 31 cases of family clusters, 25 of which were in Liwan District. The epidemic lasted from May 26 to May 29, and the R0 remained above 4.0. After May 30, R0 began to decline and remained below 1.0 from June 7. Conclusion The novel coronavirus Delta variant is highly infectious, the crowd is generally susceptible to infection and family cluster cases are easy to occur. So, it is necessary to precisely prevent and control this strain. Public security forensic experts have both medical literacy and criminal investigation capabilities, they can play a more professional role in epidemic prevention and control.


Subject(s)
COVID-19 , Epidemics , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , China/epidemiology , Female , Humans , Infant , Male , Middle Aged , SARS-CoV-2 , Young Adult
19.
Br J Psychiatry ; 220(1): 38-40, 2022 01.
Article in English | MEDLINE | ID: covidwho-1443810

ABSTRACT

The COVID-19 pandemic has had negative mental health outcomes in populations, but the suicide numbers in Finland have remained unchanged compared with expected levels based on the pre-pandemic period. We included all deaths from suicide verified by the official cause-of-death investigations, including forensic autopsy with analysis of forensic toxicology samples, between 1 January 2016 and 31 December 2020 in Finland. There was a decline in suicide incidence from 2016 to 2020 in men, and a declining tendency in suicide rates for every consecutive month during the COVID-19 pandemic period. The COVID-19 governmental policy responses do not seem to have led to an increase in suicide numbers.


Subject(s)
COVID-19 , Suicide , Cause of Death , Finland/epidemiology , Humans , Male , Pandemics , SARS-CoV-2
20.
J Forensic Leg Med ; 83: 102229, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1351743

ABSTRACT

As the COVID-19 pandemic progressed in early 2020, social distancing rules and 'lockdowns' brought face-to-face teaching in universities in the UK, and globally, to a halt, leading to an abrupt move to online teaching and learning. This article details student feedback to a course on applied forensic medicine and pathology - framed as 'safeguarding vulnerable patients' - which was adapted for delivery online in response to restrictions imposed by the pandemic. That feedback indicated that the adapted online course was well-received and, overall, it compared favourably with pervious iterations of the blended learning course, which had included a substantial face-to-face teaching component. Students remained engaged with the teaching, and they continued to see the relevance of forensic medicine to their future clinical practice.


Subject(s)
Education, Distance/organization & administration , Forensic Medicine/education , Forensic Pathology/education , Students, Medical/psychology , COVID-19/prevention & control , Education, Medical, Undergraduate , Humans , SARS-CoV-2 , United Kingdom
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