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1.
Healthcare ; 11(1):120, 2023.
Article in English | ProQuest Central | ID: covidwho-2199992

ABSTRACT

This paper reports on a study that begins to address the paucity of research around the religious motivations of Muslim carers of family members with dementia. Seven carers were recruited for interviews from the British Pakistani Muslim community concentrated in the Midlands and North of England. Interview transcripts were analysed thematically using an iterative collaborative methodology. The findings suggested that the Muslim faith plays a pivotal role as a support mechanism for individual carers and their families, but the wider faith community and its leaders did not typically offer support and could impede access to external care. This was a result of cultural pressure and lack of awareness both among religious leaders and the community as a whole. The study concluded that the inequality in access to dementia services may be constructively addressed if service providers engage with these faith concerns in the community and religious leaders to meet the needs of Muslims of British Pakistani origin.

2.
Canadian Journal of Human Sexuality ; 31(2):161-162, 2022.
Article in English | EMBASE | ID: covidwho-2198418
3.
Social Behavior and Personality ; 51(1):1-18, 2023.
Article in English | ProQuest Central | ID: covidwho-2198205

ABSTRACT

In this study I proposed a multinational model to explore how COVID-19 mortality salience influences countries' prepurchase online keyword search behavior for products during the pandemic. I used the COVID-19 death toll in 75 countries and extracted Google Trends data to develop a global search ranking that I called the religious searching popularity index (RSPI) as well as a prepurchase index (PPI) for the test products. I used terror management theory to investigate how the RSPI and product type (home use or nonhome use) moderated the relationship between the COVID-19 death toll and the PPI for each of eight products. The results suggested that purchasing did not increase for every home-use product, nor did purchasing of every non-home-use product decrease during the COVID-19 pandemic. According to the PPIs, countries with a higher RSPI had lower search impulses for Nintendo Switch, perfume, treadmills, and watches. The death toll significantly affected the PPIs of some specific home-use and non-home-use items, mainly in countries with lower RSPIs. Replication of this model will assist multinational businesses and researchers in identifying market opportunities for products.

4.
Current Drug Safety ; 18(1):1, 2023.
Article in English | EMBASE | ID: covidwho-2197766
5.
Journal of Cell Science ; 135(21) (no pagination), 2022.
Article in English | EMBASE | ID: covidwho-2196733

ABSTRACT

First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Sarantis Korniotis is first author on 'GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner', published in JCS. Sarantis conducted the research described in this article while a postdoctoral researcher in Professor Vassili Soumelis's lab at Saint-Louis Hospital, Universite de Paris, France. He is now a Senior Scientific Associate in Immunology at Intelligencia AI, Athens, Greece, investigating new signals and factors that make cells acquire regulatory or immune-suppressive properties. Copyright © 2022 Company of Biologists Ltd. All rights reserved.

6.
Future Business Journal ; 8(1):45, 2022.
Article in English | ProQuest Central | ID: covidwho-2196572

ABSTRACT

Targeting to evaluate the analytical rigour of empirical research in management education, this study's goal is to find out how students felt about the sudden shift to online education. As well as to provide an assessment of online education performance in higher education from the students' perception was it a success or a failure, or a path for change based on the findings? The study also considers the peculiarities of the Egyptian higher education system as well as the students' environment, capabilities and limitations. An online questionnaire was used to survey 625 MBA and 41 DBA students. Results show that students' satisfaction with online education is influenced by several factors, including their resources and talents. Student initiative was discovered to play a moderating role in the effects of student, instructor, and institution factors on students' satisfaction with online education. This research is being carried out during the COVID-19 outbreak to see how online instruction affects student achievement.

7.
Military Medical Research ; 9:1-24, 2022.
Article in English | ProQuest Central | ID: covidwho-2196508

ABSTRACT

The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has advanced our understanding of the pathogenesis of disease and provided valuable insights into new diagnostic and therapeutic strategies. With the expansion of capacity for high-throughput scRNA-seq, including clinical samples, the analysis of these huge volumes of data has become a daunting prospect for researchers entering this field. Here, we review the workflow for typical scRNA-seq data analysis, covering raw data processing and quality control, basic data analysis applicable for almost all scRNA-seq data sets, and advanced data analysis that should be tailored to specific scientific questions. While summarizing the current methods for each analysis step, we also provide an online repository of software and wrapped-up scripts to support the implementation. Recommendations and caveats are pointed out for some specific analysis tasks and approaches. We hope this resource will be helpful to researchers engaging with scRNA-seq, in particular for emerging clinical applications.

8.
Genome Biology ; 23:1-19, 2022.
Article in English | ProQuest Central | ID: covidwho-2196402

ABSTRACT

Spatial omics technologies enable a deeper understanding of cellular organizations and interactions within a tissue of interest. These assays can identify specific compartments or regions in a tissue with differential transcript or protein abundance, delineate their interactions, and complement other methods in defining cellular phenotypes. A variety of spatial methodologies are being developed and commercialized;however, these techniques differ in spatial resolution, multiplexing capability, scale/throughput, and coverage. Here, we review the current and prospective landscape of single cell to subcellular resolution spatial omics technologies and analysis tools to provide a comprehensive picture for both research and clinical applications.

9.
Mathematical Problems in Engineering ; 2022, 2022.
Article in English | ProQuest Central | ID: covidwho-2194214

ABSTRACT

The implementation of the urban underground logistics system (ULS) can effectively mitigate the contradiction between the surging logistics demand and the increased negativity of urban logistics. The widespread implementation of ULS still suffers from a lack of research into its operation in the marketplace, although the research on ULS system technology and network design appears to be sufficient. A new supply chain for logistics service based on ULS (ULS-SSC) was proposed, as ULS embedded in the urban logistics system could lead to the evolution of the role of supply chain participants. This article analyzed the organizational structure and operation characteristics of ULS-SSC and designed a top-down ULS-SSC operation process model based on the designed functional structure and subsystems relationship using the hierarchical colored Petri net (HCPN). The simulation results show that the integrated information management platform based on ULS can integrate urban logistics service supply chain resources and operate effectively under the two main service modes designed. The high-time delay intermediate links can be upgraded by system optimization, and the links with initial pickup and terminal distribution can be improved through outsourcing and supply chain collaboration. The findings provide new insights into the feasibility of the operation of ULS in the market and help stimulate the implementation of ULS.

10.
BioMed Research International ; 2022, 2022.
Article in English | ProQuest Central | ID: covidwho-2194207

ABSTRACT

Background. The incidence and risk of both lung cancer (LC) and tuberculosis (TB) are increasing rapidly. These two diseases frequently exist together and can influence the incidence and risk of each other. The aim of the current review was to summarize the incidence and risk of LC in TB patients, and vice versa, short out research gap, and contemplate future research perspectives. Methodology. PubMed and Scopus databases, and Google Scholar search engine were searched for epidemiological studies that investigated the incidence and risk of TB and LC, published since January 2011 to April 2022, and written in English. We used the searching keyword "tuberculosis” combined with "lung cancer” and associated medical subject heading (MeSH) to retrieve eligible research articles. We retrieved information's regarding the diagnosis of TB and LC, confounders, the associations of TB and LC, and incidence and risks of each other. Results. We found higher incidence rate and risks (1.64 to 6 times higher) of LC in TB patients in comparison to non-TB participants. However, the incidence rate and risks of TB in LC patients were comparatively low. Male patients were exhibited higher risks than female. The medical comorbidities, smoking habits, and age can also influence the associations and risks of LC in TB patients or vice versa. Conclusion. Our summarized studies might suggest that existing active TB may increase the incidence and risk of LC. However, large prospective cohort study is warranted to explore the real scenario worldwide.

11.
Heart ; 2022.
Article in English | ProQuest Central | ID: covidwho-2193879

ABSTRACT

AimsWe conducted a meta-analysis of randomised controlled trials (RCTs) of implantable haemodynamic monitoring (IHM)-guided care.MethodsPubMed and Ovid MEDLINE were searched for RCTs of IHM in patients with heart failure (HF). Outcomes were examined in total (first and recurrent) event analyses.ResultsFive trials comparing IHM-guided care with standard care alone were identified and included 2710 patients across ejection fraction (EF) ranges. Data were available for 628 patients (23.2%) with heart failure with preserved ejection fraction (HFpEF) (EF ≥50%) and 2023 patients (74.6%) with heart failure with a reduced ejection fraction (HFrEF) (EF <50%). Chronicle, CardioMEMS and HeartPOD IHMs were used. In all patients, regardless of EF, IHM-guided care reduced total HF hospitalisations (HR 0.74, 95% CI 0.66 to 0.82) and total worsening HF events (HR 0.74, 95% CI 0.66 to 0.84). In patients with HFrEF, IHM-guided care reduced total worsening HF events (HR 0.75, 95% CI 0.66 to 0.86). The effect of IHM-guided care on total worsening HF events in patients with HFpEF was uncertain (fixed-effect model: HR 0.72, 95% CI 0.59 to 0.88;random-effects model: HR 0.60, 95% CI 0.32 to 1.14). IHM-guided care did not reduce mortality (HR 0.92, 95% CI 0.71 to 1.20). IHM-guided care reduced all-cause mortality and total worsening HF events (HR 0.80, 95% CI 0.72 to 0.88).ConclusionsIn patients with HF across all EFs, IHM-guided care reduced total HF hospitalisations and worsening HF events. This benefit was consistent in patients with HFrEF but not consistent in HFpEF. Further trials with pre-specified analyses of patients with an EF of ≥50% are required.PROSPERO registration numberCRD42021253905.

12.
BMJ Open ; 12(12), 2022.
Article in English | ProQuest Central | ID: covidwho-2193767

ABSTRACT

IntroductionPostpartum depression (PPD) affects around one in seven women globally, with these women in need of non-pharmaceutical treatment strategies. There is a long history of the benefits of singing for maternal mental health, and promising research exists showing the clinical effectiveness of group singing. Group singing interventions are being scaled up to support new mothers in the United Kingdom, but we do not know if such an intervention may benefit women in different cultural contexts. This protocol focuses on exploring the feasibility of implementation and perceived impact of a 10-week group singing intervention for new mothers in Romania and Denmark eliciting signs of PPD.Methods and analysisData will be collected from up to 48 women with a score ≥10 on the Edinburgh Postnatal Depression Scale (EPDS) participating in a 10-week group singing intervention in Denmark or Romania, as well as a range of project stakeholders. The singing classes will take place in person and be facilitated by professional singing leaders. Feasibility of implementation will be analysed through qualitative data (eg, focus groups, interviews) and quantitative data (eg, the Feasibility of Intervention Measure). Perceived impact will be explored via surveys that include mental health measures (EPDS, Multidimensional Scale of Perceived Social Support, WHO Five Well-Being Index) from singing intervention participants (at weeks 1, 6, 10) and focus groups. Descriptive statistics, repeated measures analysis of variance and analysis of covariance will be used to analyse quantitative data. Framework method and thematic analysis will be used to analyse qualitative data.Ethics and disseminationThe national ethics committees in Romania (IRB-PH Protocol #2021-211217-012) and Denmark (case number 1-10-72-274-21) have approved the study, as has the Ethics Review Committee at the World Health Organization (ERC.0003714). All participants will be required to provide informed consent. Results will be disseminated by reports published by the WHO Regional Office for Europe, peer-reviewed publications and at conferences.

13.
BMJ Open ; 13(1), 2023.
Article in English | ProQuest Central | ID: covidwho-2193757

ABSTRACT

ObjectivesThe Computer-Aided Risk Score for Mortality (CARM) estimates the risk of in-hospital mortality following acute admission to the hospital by automatically amalgamating physiological measures, blood tests, gender, age and COVID-19 status. Our aims were to implement the score with a small group of practitioners and understand their first-hand experience of interacting with the score in situ.DesignPilot implementation evaluation study involving qualitative interviews.SettingThis study was conducted in one of the two National Health Service hospital trusts in the North of England in which the score was developed.ParticipantsMedical, older person and ICU/anaesthetic consultants and specialist grade registrars (n=116) and critical outreach nurses (n=7) were given access to CARM. Nine interviews were conducted in total, with eight doctors and one critical care outreach nurse.InterventionsParticipants were given access to the CARM score, visible after login to the patients' electronic record, along with information about the development and intended use of the score.ResultsFour themes and 14 subthemes emerged from reflexive thematic analysis: (1) current use (including support or challenge clinical judgement and decision making, communicating risk of mortality and professional curiosity);(2) barriers and facilitators to use (including litigation, resource needs, perception of the evidence base, strengths and limitations), (3) implementation support needs (including roll-out and integration, access, training and education);and (4) recommendations for development (including presentation and functionality and potential additional data). Barriers and facilitators to use, and recommendations for development featured highly across most interviews.ConclusionOur in situ evaluation of the pilot implementation of CARM demonstrated its scope in supporting clinical decision making and communicating risk of mortality between clinical colleagues and with service users. It suggested to us barriers to implementation of the score. Our findings may support those seeking to develop, implement or improve the adoption of risk scores.

14.
BMJ : British Medical Journal (Online) ; 380, 2023.
Article in English | ProQuest Central | ID: covidwho-2193675

ABSTRACT

Stephanie Kraft and colleagues argue that doing more to acknowledge the important role of research participants could help recruitment

15.
Tourism Review of AIEST - International Association of Scientific Experts in Tourism ; 78(1):203-217, 2023.
Article in English | ProQuest Central | ID: covidwho-2191656

ABSTRACT

Purpose>The purpose of this study is to systematically analyze the evolution of health tourism development, identify relevant themes and segments of health tourism research and offer future research directions and practical implications for academic researchers and tourism practitioners worldwide using China as an example.Design/methodology/approach>Using a bibliometric analysis, the present study comprehensively analyzes the theme, segments and the evolution of health tourism research over the past 40 years in China.Findings>Major findings show that health tourism research in China could be divided into four stages with different characteristics, and three segments, including wellness tourism, health and wellness tourism and medical tourism. Findings also reveal the trend of health tourism development tends to be industrialized, diversified and systematic under the guidance of recent policies. Theoretically, based on the theoretical framework developed by Hall (2011), the present study contributes to the establishment and extension of the framework for health tourism within the context of China. Practically, findings can provide health tourism-related policy implications for the future development of health or health sector-integrated tourism.Research limitations/implications>The study proposes possible collaboration between government and academia in terms of health tourism-related policy formulation.Originality/value>Through 40-year bibliometric analysis of health tourism evolution in China, the present study explores the main themes of health tourism development, identifies the segments of health tourism and analyzes the development stages of health tourism. Findings should be of use to international readers to better understand the uniqueness of health tourism development and find out possible future health tourism development research directions. As a result, major contributions of this paper are the comprehensive analysis of the evolution of health tourism research and the implications on other countries and regions to adopt a pragmatic approach to explore the trend and unique characteristics of health tourism for future development.

16.
Quality Assurance in Education ; 31(1):91-106, 2023.
Article in English | ProQuest Central | ID: covidwho-2191615

ABSTRACT

Purpose>This study aims to evaluate a culture-based blended learning multilingual course created for adult learners in ten languages and the development of learners' 21st-century skills during its implementation in six European countries – Croatia, Latvia, Slovenia, Romania, Poland and Czechia in the COVID-19 period.Design/methodology/approach>A cross-sectional survey of 638 participants was conducted using a paper-based questionnaire. Data analysis was carried out applying Bereday's four-step model comprising description, interpretation, juxtaposition and comparison to find out similarities and differences among various groups of learners.Findings>Overall, learners have developed their 21st-century skills, but the improvement has not been the same for all target audiences. Learners with economic, social and cultural barriers were more positive in their evaluation than those with geographic and learning obstacles.Research limitations/implications>The research was conducted during the COVID-19 pandemic, and the face-to-face stage was replaced with online learning on virtual platforms, which impacted the research results. The results cannot be generalized to all adult learners as significant differences were discovered among various target groups of learners.Practical implications>The course may be implemented for formal and non-formal adult education when face-to-face teaching/learning is restricted.Social implications>The findings indicate that the course is especially suitable for learners with economic, social and cultural obstacles to learning.Originality/value>The article focuses on the use of blended learning in non-formal/informal adult education, which is a less widely researched area. The target course implemented during the COVID-19 pandemic shows a novel way of engaging adult learners in lifelong learning, including those with certain barriers to learning.

17.
Quality Assurance in Education ; 31(1):1-3, 2023.
Article in English | ProQuest Central | ID: covidwho-2191614

ABSTRACT

[...]educational institutions should create organizational environments that enable faculty members, who are the people most directly involved, with structure and support to dynamism. [...]this Special Issue is an important collection of scholarship that examines how educators are using a range of flexible learning formats due to the environmental circumstances of the COVID-19 pandemic. [...]social behavioral aspects of online academic performance are researched in The Relationship Between Student Motivation and Academic Performance: The Mediating Role of Online Learning Behavior and The Relationship Between Social Media Based Teaching and Academic Performance During Covid-19.

18.
Mental Health and Social Inclusion ; 27(1):1-2, 2023.
Article in English | ProQuest Central | ID: covidwho-2191588
19.
International Journal of Organizational Analysis ; 31(1):1-6, 2023.
Article in English | ProQuest Central | ID: covidwho-2191421

ABSTRACT

Businesses can survive or flourish in this unstable and fragile environment only if they get fresh insights about how the new marketplaces function and how to successfully operate in them (Öberseder et al., 2013). [...]for all organisations hoping to endure and grow in the post-pandemic climate, organisational resilience, based on market knowledge, is a desired, if not an essential, feature. [...]Soultana Anna Toumpalidou and Kleopatra Konstantoulaki, in their paper, tap on the new form of higher education provision in the pandemic economy;more specifically, the authors investigate the effect of attitudes towards distance learning as a drive of university students' decision-making. To this end, they study 1,550 university students in Greece and reveal three equally sized clusters, namely, technology mature, technology conservatives and sceptics of e-learning, pertaining to their attitudes towards online services provision in the higher education sector. [...]Kavita Sharma and Emmanuel Elioth Lulandala in their comprehensive research explore the impact of Covid-19 on the consumption of Over the Top (OTT) media services in India. [...]Miftachul Huda in his qualitative study examines the initiative of a low-price hotel in Malaysia to restore the financial sustainability through empowering the digital marketplace strategy in the tourism resilience sector during the Covid-19 pandemic.

20.
Employee Relations ; 45(1):45-68, 2023.
Article in English | ProQuest Central | ID: covidwho-2191359

ABSTRACT

Purpose>This paper aimed to revise and further validate the published e-work life (EWL) scale. The EWL scale was originally developed to assess theoretically relevant aspects of the remote e-working experience related to four main areas: organisational trust, flexibility, work–life interference and productivity.Design/methodology/approach>A number of changes were implemented to the scale (i.e. including new items, rewording of existing items) following a recent qualitative study conducted by the authors. The two studies outlined in this paper, conducted within discrete remote e-working populations, resulted in a validated and adjusted 20-item version of the scale.Findings>Study 1 performs confirmatory factor analysis (CFA) on data from a sample of 399 remote e-workers (57.9% female) in UK to check the factor structure of the revised version of the EWL scale and the reliability of the posited dimensions. Results provided support for a 20-item scale, replicating the factorial structure of the original version. Study 2 tests and confirms the factorial structure of the final 20-item EWL scale in an independent sample of 366 remote e-workers (48.6% female) in UK. Study 2 provides further evidence of EWL scale's reliability and validity, with the four factors of the scale being significantly correlated with positive mental health, detachment from work and technostress.Originality/value>The EWL scale is a very timely and important tool which provides an overall framework of the key areas that are affecting remote e-workers' life;whose greater understanding may better prepare organisations to adapt work arrangements and introduce support policies and guidance.

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