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1.
Osteopathic Family Physician ; 13(6):9-16, 2021.
Article in English | EMBASE | ID: covidwho-1822746

ABSTRACT

Introduction: Telemedicine is an emerging field in which physicians can interact electronically with patients to improve health. During the COVID-19 pandemic, the use of telemedicine has grown exponentially. As physicians work to provide equally high-quality care for their patients remotely, their experiences must be considered. Methods: This study utilized an online anonymous survey of physicians to assess their satisfaction, comfort level and student involvement when using telemedicine for patient care. Results: Overall, physicians’ experiences with the integration of telemedicine into their practices varied based on gender, the presence of medical students, age and prior experience with telemedicine. Physicians are more comfortable with telemedicine now than they had been prior to the start of the COVID-19 pandemic, and physicians who had prior experience were less likely to find it stressful to incorporate. Physicians in both the youngest (30–39 years old) and oldest (60 and older) categories reported the highest levels of satisfaction with telemedicine. Female physicians indicated they will be more likely to incorporate more telemedicine into practice in the future, beyond the COVID-19 pandemic. Of the specialties surveyed, family physicians report the lowest levels of comfort and satisfaction with telemedicine. Conclusion: Physician respondents of this survey provided valuable data on the perceptions of the widespread incorporation of telemedicine during the COVID-19 pandemic. Further research can follow which physicians choose to keep telemedicine integrated into their practices and how the demand for these virtual visits may change in the coming months.

2.
Pakistan Journal of Medical Sciences ; 38(5), 2022.
Article in English | EMBASE | ID: covidwho-1822611

ABSTRACT

Background and Objectives: All medicine and healthcare undergraduates were encountered with terminations and delays of professional examinations. These alterations were on topmost of other tasks the COVID-19 pandemic carried out for instance not roaming, covered faces with masks and specifically segregation. This interruption of normal life was a major cause of mental health disaster and it is no surprise that medicine and healthcare undergraduate has had high rates of psychological effects including hopelessness, stress and suicidal thoughts. This study aimed to investigate the unmediated connection of anxiety and stress related mental health decline and suicide among medical and nonmedical undergraduates during the pandemic of covid-19. Methods: A multidiscipline online cross-sectional comparative study design was chosen for this study conducted from November 2020 to January 2021 with a pre-validated questionnaire to collect responses from sample size 1290. SPSS-21 used for descriptive analysis of means, S.D, ANOVA and spearman’s correlations. Forward step-wise model of linear regression applies for true significant bivariate relationship (p<.001) Results: The result shows that all three cohorts were affected. Among the non-medical cohorts, B-Pharmacy students had the high level (p<.001) of anxiety with suicide ideation response (n=200;39.2%), along with lowest level of envisions care (19.5%;p<.001) in pandemic. Control and independent variable had a strong negative effects on B-Pharmacy and medical students with p<.000. Conclusions: This study offered more data that the concerns, anxieties and uncertainties caused by pandemic COVID-19, don’t roll out alone but remain as long-lasting problems demanding ongoing attention.

3.
FASEB Journal ; 35(SUPPL 1), 2021.
Article in English | EMBASE | ID: covidwho-1821854

ABSTRACT

In March 2020, TTUHSC opened a new 20,000sf Institute of Anatomical Sciences for human gross anatomy. When the COVID-19 pandemic struck and many schools shifted from in person to online teaching, we hypothesized that if safety measures were used, in person cadaveric anatomy could be safely taught without a decrease in student performance. To test this, we reduced onsite attendance to less than 25% of room capacity. Masks were required at all times and students were instructed to social distance. Six students were assigned per cadaver, but only two students dissected at a time. The other four students reviewed and completed dissections and/or reviewed in groups of two at other allotted times. Thus, students dissected only every third lab. Dissection and lab review attendance was mandatory and students were nearly 100% compliant. Teaching assistants recorded dissected prosections reviews, and these videos were uploaded to password protected course files for independent learning. Students were provided iPads in the laboratory and access to three software packages for use on and off site. All students had access to multiple formative quizzes and exams, and three new online practice practical exams were created. To help reduce testing anxiety, a pass/fail system replaced categorical grading. However, all written and practical exams were conducted on site and in person. At TTUHSC, we have developed an exam question database to track historical student performance including a 25-question optional pre-block practice exam used to assess incoming student anatomical aptitude. In 2020, 90% of incoming students (93% in 2019) took the pre-block exam and scored an average of 28% (24% in 2019). In 2020, despite vastly different content delivery approaches (>80% of lectures were on Zoom) and reduced in-person dissection requirements, students modestly outperformed their 2019 counterparts. Overall exam averages were 89% in 2020 compared to 87% in 2019. If a categorical system was in place, 66% of students would have earned Honors or High Pass in 2020 compared to 61% in 2019. Our formative assessments were highly predictive of summative exam performance, and students reported that they reduced exam stress. Furthermore, summative exam averages correlated strongly with NBME performance (p<0.0001, r =0.63). TTUHSC medical students estimated that a majority of their peers at other medical schools did not have any in person dissection in 2020. Our students ranked in person laboratory dissection as the most useful learning activity, 88% reported that our COVID-19 preparations were very good to outstanding, and 97% were satisfied with the quality of their anatomy education. We conclude that 1) When using appropriate precautions, in person cadaveric anatomy can be taught safely during a pandemic;2) cadaveric dissection is essential for mastery of anatomical concepts;and 3) coupling online learning modalities with rigorous formative assessments prevented a modest reduction in cadaveric dissection opportunities from negatively impacting student performance. 2.

4.
Revista Medica de Rosario ; 88(1):7-15, 2022.
Article in Spanish | EMBASE | ID: covidwho-1820566

ABSTRACT

Introduction: Mental health is a priority public health problem, with medical students being a group susceptible of suffering from mental disorders. Objective: To determine the association between, on the one hand, the presence of depression, stress and/or suicidal ideation and, on the other, the academic performance of medical students from a Peruvian university in the midst of the COVID-19 pandemic. Materials and methods: Cross-sectional, analytical and prospective study carried out in 241 students from 1st to 6th year of medicine. Data collection was carried out between March and May 2021. The presence and levels of stress, depression and risk of suicidal ideation were determined using the Perceived Stress Scale-14 (EEP-14), the Zung Scale for Depression (EZ-D) and the Beck Suicidal Ideation Scale (ISB), respectively;on the other hand, academic performance was evaluated with the Reyes Murillo learning assessment scale. A bivariate analysis was performed using the chi square test (significance level of p<0.05) to establish the association between the study variables. Results: Most of the students had an average academic performance (70.12%). The prevalence of depression, stress, and suicidal ideation was 33.61%, 94.19%, and 88.79%, respectively. Academic performance was significantly associated with the presence of depression (p=0.018), but not with the presence of stress (p=0.669), or risk of suicidal ideation (p=0.438). Conclusions: Only depression was significantly associated with academic performance, although its prevalence was much lower than stress or suicidal ideation, so it is necessary for the university to implement strategies aimed at improving the mental health of this population;this will not only improve its quality of life, but also its academic performance.

5.
Journal of the Liaquat University of Medical and Health Sciences ; 21(1):44-49, 2022.
Article in English | EMBASE | ID: covidwho-1818978

ABSTRACT

OBJECTIVE: To assess the psychological impact of the COVID-19 pandemic on health care workers in tertiary care hospitals of Karachi. METHODOLOGY: This is a multicentric cross-sectional study conducted at tertiary care hospitals of Karachi (Pakistan). A total of 350 health care workers, including both males and females, from different private and Government tertiary care hospitals, were approached and enrolled after fulfilling the selection criteria from May to Aug 2020. The semi-structured Performa was used for demographic details while the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD 7) were administered to evaluate depression and anxiety, respectively. RESULTS: Out of 350 participants, 220 (62.8%) have depression in this study, while 206 (58.8%) have anxiety. The degree of depression was mild in 81 (23.1%) of health care workers, moderate in59 (16.8%), moderately severe in 50 (14.2%), severe in 30 (8.6%). Similarly, mild anxiety was present in 75 (21.4%), moderate in 74 (21.1%), and severe anxiety in 57 (16.3%) persons. The most common problem they faced is ―Fear of transmission of disease family /close friends, being present in 311 (88.9%) p-value = 0.014. CONCLUSION: It is evident that health care workers are affected with depression and anxiety due to pandemic. It is necessary to take appropriate steps to manage the psychological impact of the stress to be more productive in their respective fields.

6.
Archivos Venezolanos de Farmacologia y Terapeutica ; 41(1):52-57, 2022.
Article in Spanish | EMBASE | ID: covidwho-1818554

ABSTRACT

Introduction: The study places in the limelight the effects of social isolation decreed by the Peruvian government because of the sanitary emergency due to the presence of Covid-19, on the socioemotional aspects of emotional intelligence and how these influence intrapersonal and interpersonal relationships that constitute fundamental basis of the institutional climate in teachers of educational institutions in the district of Co-mas. Methodology: quantitative approach study, basic type, explanatory-causal level, non-experimental-transectional de-sign, hypothetical-deductive method. Census study, made up of 139 teachers of regular basic education. The instruments for data collection were: for emotional intelligence, the BarOn Emotional Coefficient Inventory (I-CE), adapted to the Peruvian context, and for the institutional climate variable, the Work Climate Scale (CL-SP) questionnaire. Results: Ordinal logistic regression was applied for the results, due to the nature of the variables whose measurement was through the ordinal scale. Considering four assumptions, the model fit test, model goodness-of-fit test, parameter estimates and the Pseudo R-squared test. Conclusions: they indicate that the variability of the institutional climate depends on emotional intelligence, as well as on its theoretical components, self-knowledge, self-regulation, motivation, empathy and social ability.

7.
Open Access Macedonian Journal of Medical Sciences ; 10:318-324, 2022.
Article in English | EMBASE | ID: covidwho-1818254

ABSTRACT

BACKGROUND: Nurses are at high risk of experiencing stress when treating patients with COVID-19. The presence of an outbreak could also result in burnout among nurses due to job stress, poor hospital resources for the treatment, and inadequate support from family and friends. All of these related obstacles might be interfered with the intention of nurses to work during a pandemic. AIM: The objective of the study was to identify perceived stress and intention to work during the COVID-19 pandemic among nurses. METHODS: An online-based cross-sectional study was conducted among nurses in Indonesia. There were 238 responses received. Multiple regression analysis was used to examine for data analysis. RESULTS: There was a significant correlation between perceived stress and intention to work (p < 0.001). The regression model showed the variance in the perceived stress with other main predictors. CONCLUSIONS: To maintain an adequate workforce during the pandemic, hospital management should ensure adequate hospital goods supply and deploy retention strategies to retain clinically experienced nurses.

8.
International Journal of Dermatology and Venereology ; 5(1):20-26, 2022.
Article in English | EMBASE | ID: covidwho-1816313

ABSTRACT

Objective: Pemphigus is a life threatening autoimmune bullous disease which involves the skin and mucous membranes of the stratified squamous epithelium. The global distribution of Pemphigus varies according to genetic, ethnic, socioeconomic, and cultural backgrounds. The purpose of our study is to evaluate the epidemiological features of pemphigus a single center in Morocco and compare our results with those reported elsewhere. Methods: A retrospective analysis was conducted of 302 pemphigus patients seen between 1990 and 2020 in the Dermatology Department of Ibn Sina Hospital (Rabat, Morocco). We further collected all the Moroccan scientific researches published by now to compare. Results: The average annual incidence was 0.32/100,000 inhabitants. The incidence doubled to 0.72 in 2020. The most common variant was pemphigus vulgaris (125 cases) followed by pemphigus erythematosus (99 cases), pemphigus foliaceous (40 cases), and vegetans (27 cases). The female to male ratio was 0.75, the average age at onset was 53years old and the mean duration of the disease before diagnosis was 13.36months. Conclusion: This study joins the main characteristics of pemphigus in the Maghreb and around the world (pemphigus vulgaris most frequent subtype). In 2020, an epidemiological peak occurred during the coronavirus disease 2019 pandemic;probably related to stress and delayed time consultation for fear of contracting the severe acute respiratory syndrome coronavirus 2.

9.
Brain Injury ; 36(SUPPL 1):3, 2022.
Article in English | EMBASE | ID: covidwho-1815741

ABSTRACT

Objective: Evaluate the effectiveness of a Compassion Focused Therapy (CFT) group for adults with Acquired Brain Injury in the context of coping with stressors. Design: The original quantitative (pre/post questionnaires) design was altered due to COVID-19 restrictions ending the group prematurely at session 7 of 10. Contact with the group continued by e-mail for the next 3 months. Qualitative interviews were then carried out 6 months later and questions on the altered ending were included. Method: Out of the eight participants who started the group, six consented to take part in the qualitative interview which due to COVID-19 restrictions were completed remotely. An interview protocol focusing on eight key areas (including session content, group experience and impact of COVID-19 restrictions on session completion) was utilized. The content of the interviews were analyzed using interpretative phenomenological analysis. Results: Three core themes emerged from the interviews, namely the usefulness of the compassion focused model to address stress, the importance of group cohesion and the timing of the intervention. A preference was expressed for face-toface group work rather than through technology options. Conclusions: Participants successfully transferred strategies discussed during the group to daily life and reported increased coping with stress as a result. The feedback provides encouragement for continued provision of this type of therapeutic group to clients when COVID-19 restrictions ease. The positive impact of attending a CFT group adds to the growing body of research in this area.

10.
Journal of Clinical and Diagnostic Research ; 16(SUPPL 2):79, 2022.
Article in English | EMBASE | ID: covidwho-1798708

ABSTRACT

Introduction: Health care students have baseline elevated rates of anxiety, depression and burnout. However, not much is known regarding COVID-19's psychological impact on home-confined medical & nursing students. Aims: This study aimed at assessing the prevalence of stress, anxiety and depression among health care students in Erode district, Tamilnadu during lockdown due to the outbreak of COVID-19. Materials and Methods: This descriptive cross-sectional study was conducted via an online survey completed by students studying an MBBS and a Nursing degree in Erode district, Tamilnadu. The validated previously published Depression, Anxiety and Stress Scale (DASS-21) questionnaire was used as a part of the online survey to assess students' stress, anxiety and depression scores. The data were evaluated using descriptive statistics, the Mann-Whitney U test, and the Kruskal-Wallis test. Results: A total of 273 health care students (males: 29.3%, females: 70.7%) completed the survey. 50.9% of students are MBBS students, and 49.1% are nursing students. From those surveyed, the prevalence of depression, anxiety, and stress in different levels was 40.3% (110), 41.4% (113), and 30% (82), respectively, which are higher during lockdown. Mean depression (10.25 vs 7.75, p=0.05), anxiety (8.53 vs 6.6, p=0.05) and stress (11.76 vs 9.30, p=0.05) scores were higher among females than males. Final year students are having more depression (F=10.37, p=0.04), anxiety (F=9.93, p=0.05), and stress (F=9.97, p=0.05) than others, and it is confirmed using one-way ANOVA F-test. Conclusion: During the COVID-19 epidemic, stress, anxiety, and depression levels among health care students in Tamil Nadu were high. As a result, immediate and suitable psychological therapies for healthcare students should be undertaken to prevent the psychological harm caused by the COVID-19 epidemic, which might negatively impact their learning.

11.
Journal of Clinical and Diagnostic Research ; 16(SUPPL 2):21, 2022.
Article in English | EMBASE | ID: covidwho-1798706

ABSTRACT

Introduction: A novel coronavirus (COVID-19), caused a series of acute atypical respiratory syndrome termed as SARS CoV-2. It has a varying degrees of symptoms like headache, high fever, dizziness, generalized weakness, diarrhoea and vomiting. But primarily it affects the respiratory system causing breathlessness and sometimes may be fatal. People recovered from the illness had variety of physical and mental illness. Aims: To find the effectiveness of virtual therapeutic exercises and mindfulness programme among the subjects recovering from COVID-19. Materials and methods: A total number of 32 male subjects aged between (55 - 70) years were included in this study. The subjects were included based on the prescription of a medical officer/ Curved length of Aortic Knuckle (AKC), total length of Left Heart Border (LHBT) and Aortic Knuckle Index (AKI) were measured. Statistical analysis was carried out with the help of IBM-SPSS (IBM Corporation) and Microsoft Excel. Results: AKC and AKI were measured,and correlated with total lenght of LHBT. A positive correlation between AKC, AKI and LHBT was noted. Conclusion: Simple measurement of aortic knob in PA chest x-ray may help in predicting cardiovascular disorder. pulmonologist. The duration of the study was eight weeks. Fitness assessment scale, hamilton stress anxiety scale and modified respiratory assessment scale was used. The study was conducted in the Symbiosis Medical College for Women, Pune. Results: The statistical analyses were done using the SPSS software version 18 executed at a 95% confidence interval. A paired t-test was done to find the effectiveness of the therapeutic exercises. The level of significance in all tests was set to p < 0.05. Positive changes were observed in health-related fitness among the subjects. Conclusion: This study reports about finding that virtual therapeutic training also provides the best results in physical and mental health among the patients recovering from COVID-19.

12.
Journal of Clinical and Diagnostic Research ; 16(SUPPL 2):54, 2022.
Article in English | EMBASE | ID: covidwho-1798705

ABSTRACT

Introduction: Medical teachers have been experienced different kinds of psychological stress and anxiety during COVID-19 .The pandemic has not only affected the mental state of students , since teachers have also accumulated a high level of stress since beginning of crisis .This stress has often been accompanied by symptoms of anxiety ,depression and sleep disturbances as consequence of the increased workload resulting from home teaching. Aim: The aim of study was to investigate the stress, anxiety and depression on medical teachers during COVID-19. Materials and methods: The study was carried out in Saveetha medical college. An online survey was conducted and disturbuted to the medical teachers via the google forms containing questionnaire session. The level of stress measures based on the 10 items perceived stress scale .The level of anxiety was measured based on the 7 items generalized anxiety disorder scale. Results: A total of 370 participants responded to perceived stress component of survey of whom 17% had high stress, 67% had moderate stress, 15% had low perceived stress. Being female was significantly associated with moderate /high stress. A Total of 201 participants responded to generalized anxiety disorder component of the survey ,of whom had mild anxiety (28%), had moderate anxiety (39%) and 46% had severe anxiety .A total of 169 participants responded to the depression component of survey of whom 72% had high depression 18% low depression. Conclusion: A considerable proportion of medical teachers stress and anxiety during COVID-19 outbreak .There a need to establish mechanisms to reduce the risks of stress and anxiety among medical teachers.

13.
International Journal of Pharmaceutical Sciences Review and Research ; 73(1):114-119, 2022.
Article in English | EMBASE | ID: covidwho-1798544

ABSTRACT

Covid-19 pandemic has impacted the lives of everyone in one way or another. The healthcare workers being the group directly or indirectly working with the covid patients are at higher risk which can lead to increased anxiety among them. This is a prospective, cross-sectional, observational study among healthcare workers who were involved with patient care during the initial stages of the pandemic. Generalized Anxiety Disorder Assessment scale (GAD-7 scale) and WHO-5 wellbeing scale were distributed among healthcare workers through an online survey as a google form. Out of 95 participants who consented about 80% were frontline workers among which the majority (82%) were doctors and nursing staff (11.6%). The mean GAD-7 score observed was 6.06 ± 5.12 with a majority of the participants having minimal anxiety (44.44%). The mean WHO-5 wellbeing score was 55.83 ± 26.57. The present study showed a majority of the health care worker has minimal anxiety but the low mood was prevalent in many which could be due to increased workload and stress.

14.
Critical Care ; 26(SUPPL 1), 2022.
Article in English | EMBASE | ID: covidwho-1793846

ABSTRACT

Introduction: Mitochondrial dysfunction has been linked to the persistent hypoxia and altered aerobic glycolytic metabolism seen in COVID-19 patients. This observational pilot study assessed mitochondrial function in COVID-19 patients and healthy controls (HC) utilizing in vivo and ex vivo techniques. Methods: This single center observational study examined COVID-19 patients on two time points, the first within 72 h after intensive care admission (T1), and the second seven days after T1 (T2). HC were age and sex matched to the included COVID-19 patients. In vivo epidermal mitochondrial oxygen utilization was analyzed using the COMET (Cellular Oxygen METabolism) monitor, which employs the protoporphyrin- IX triplet state technique. Ex vivo measurements consisted of in vitro mitochondrial respiration analyzed by the Oroboros O2k respirometer and free mitochondrial DNA (fMtDNA) which was isolated from plasma and quantified by qPCR. Results: 16 COVID-19 sepsis patients and 16 HC were included. The median MitoVO2 of COVID-19 patients on T1 was 4.6 mmHg s-1 [IQR;3.6-6.0], 4.6 mmHg s-1 [IQR;3.9-5.8] on T2 and 5.3 mmHg s-1 [IQR;4.5-6.3] in the HC. Basal platelet respiration did not differ substantially between the three groups, whilst PBMC basal respiration was increased by approximately 80% in the T1 group when contrasted to T2 and the HC. fMtDNA was 14 times higher in the T1 group and 5 times higher in the T2 group when compared to the HC. Conclusions: fMtDNA levels were increased in COVID-19 patients, but were not associated with decreased mitochondrial O2 consumption in vivo in the skin, and ex vivo in platelets or PBMC. This suggests the presence of mitochondrial stress, with concurrent preservation of mitochondrial respiration and function. It must be noted that due to the timing of T1, the optimal measurement window could have been missed. Therefore, the role of mitochondrial dysfunction in COVID-19 should be further evaluated at different time points.

16.
Pakistan Journal of Medical and Health Sciences ; 16(2):903-906, 2022.
Article in English | EMBASE | ID: covidwho-1791219

ABSTRACT

Background: The biggest dilemma of today's world is COVID-19. This pandemic situation has completely engulfed the globe with a rapidly increasing number of cases and has affected a great number of lives along with their lifestyle including the educational sector. Objective: This study explores the impact of COVID-19, how frequent lockdown, and online learning have affected the mental health of the students of medical college. Methods: A cross-sectional study was conducted among the medical students of Karachi, in September 2021, in Jinnah Medical and Dental College. A total of 312 medical students were enrolled in the study. Out of which 208 were females and 104 were males. Depression Anxiety Stress Scale-21 (DASS-21) was used to assess the mental health of students of medical college. Results: The results of the study revealed that a total of 312 medical students were enrolled in the study;belonging to the age group of (18-25) years. Approximately 104 (66 %) of female students experienced depression, 44 (21%) anxiety, and 60 (28%) stress. Hence gender and year of study of the participants were found to be significant (p-value<0.05). The odds of first-year students showed high levels of anxiety as compared to final-year students (OR = 1.679, 95% CI [1.202-2.634], P = 0.002). Conclusion: This study will help in making relevant policies, mental health strategies and providing a better framework for the medical colleges and universities which is essential for the mental health of students.

17.
Journal of Clinical and Diagnostic Research ; 16(3):LC20-LC25, 2022.
Article in English | EMBASE | ID: covidwho-1780258

ABSTRACT

Introduction: Mental health and well-being is as important as physical health during pregnancy. But the Coronavirus Disease 2019 (COVID-19) pandemic has caused more anxiety and stress among pregnant women. The augmented levels of anxiety and stress may have detrimental effects on antenatal women. Anxiety and depression in pregnancy can lead to adverse pregnancy outcomes like increased risk of abortions, preterm labour and even foetal deaths. Aim: To assess the anxiety and stress levels among pregnant women attending a tertiary care hospital in Thiruvananthapuram, Kerala during the COVID-19 pandemic and to determine the associated factors. Materials and Methods: A cross-sectional study was conducted among 348 pregnant women attending a tertiary care teaching hospital in Thiruvananthapuram District in Kerala during the period October and November 2020 using a validated tool, Pandemic Anxiety Stress Scale for pregnant women. Higher scores indicating higher perceived anxiety stress with a maximum score of 60, categorised as normal, mild, moderate and severe with score between 0-14, 15-29, 30-44, and 45-60, respectively. Qualitative variables were expressed in frequency and percentage. Multivariate logistic regression was done to determine the factors associated with anxiety and stress. The p-value <0.05 was considered significant. Results: Mild anxiety and stress were seen in 160 (45.98%) pregnant women, 89 (25.57%) had moderate and 7 (2.01%) had severe anxiety and stress, 92 women had no anxiety. A total of 145 (41.67%) pregnant women were scared of vertical transmission to their baby. Multivariate logistic regression revealed that residents in urban area and pregnant women with other co-morbidities associated with pregnancy were the two significant factors (p<0.05) associated with anxiety-stress. Conclusion: About one-fourth of pregnant women had moderate or severe level of anxiety and stress. Antenatal women with pregnancy related diseases and those living in urban area had more anxiety and stress during pandemic. Measures need to be taken by health system to address the mental health of pregnant women.

18.
Biological Psychiatry ; 91(9):S25-S26, 2022.
Article in English | EMBASE | ID: covidwho-1777990

ABSTRACT

Background: Poor sleep during pregnancy is very common and is associated with increased risk of adverse maternal and infant outcomes. Maternal psychosocial stress has been found to negatively impact sleep. The recent outbreak of COVID-19 has exposed many individuals to an unprecedented level of stress, that will continue for an unknown period of time. Studies are showing that all these factors may not only increase levels of stress, but also influence sleep health. Methods: From March 2020-May 2021, participants were recruited as part of the COVID-19 Mother Baby Outcomes (COMBO) study at Columbia University. Survey data on maternal depression (PHQ-9), perceived stress (PSS), COVID-related stress, and sleep health (Pittsburgh Sleep Quality Index, PSQI) were collected. For this analysis, we excluded mothers identified as depressed based on PHQ9. Regressions analyses were implemented to estimate the associations between PSS and COVID-related stress and multiple domains of sleep, accounting for covariates (maternal age, education, gestational age covid infection in pregnancy, time of the pandemic). Results: Our sample consisted of N=155 women;Gestational age at assessment: 30.6±5.8 weeks;Age: 32.2±5.0 years;non-Hispanic White=66, non-Hispanic Black=12, Hispanic=56, Asian=16, Other=5;69% 4-year college/graduate degree. Mean PSS was 18.3±7.0 and COVID-related stress was 3.9±1.6. COVID-related stress negatively affected subjective sleep quality (β=0.3±0.1, p<0.01), latency (β=0.4±0.1, p<0.001) and sleep disturbances (β=0.5±0.2, p=0.003). Increased PSS negatively affected sleep duration (β=0.09±0.2, p<0.001), efficiency (β=0.08±0.02, p<0.001), and daytime dysfunction (β=0.08±0.03, p=0.01). Conclusions: Our results suggest that stress related to the current COVID-19 pandemic is uniquely affecting maternal sleep health during pregnancy. Funding Source: R01MH126531;Eunice Kennedy Shriver National Institute of Child Health and Human Development under grant number P2CHD058486, awarded to the Columbia Population Research Center Keywords: Sleep, Perceived Stress, COVID-19, Pregnancy

19.
Embase; 2021.
Preprint in English | EMBASE | ID: ppcovidwho-331114

ABSTRACT

Coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to escalate worldwide and has become a pressing global health concern. This article comprehensively reviews the current knowledge on the impact of COVID-19 over pregnant women and neonates, as well as current recommendations for their management. We also analyse previous evidences from viral respiratory diseases such as SARS, Middle East respiratory syndrome, and influenza that may help to guide clinical practice during the current pandemic. We collected 23 case reports, case series, and case-control studies (18 from China) comprising 174 pregnant women with COVID-19. The majority of mothers showed a clinical presentation of the disease similar to that of non-infected adults. Preliminary evidences point towards a potentially increased risk of pregnancy adverse outcomes in women with COVID-19, with preterm delivery the most frequently observed (16.7%) followed by fetal distress (9.77%). The most commonly reported adverse neonatal outcomes included respiratory symptoms (7.95%) and low birth weight (6.81%). A few studies reported other maternal comorbidities that can influence these outcomes. Mothers with other comorbidities may be at higher risk of infection. Mother-tochild transmission of SARS-CoV-2 appears unlikely, with no study observing intrauterine transmission, and a few cases of neonatal infection reported a few hours after birth. Although the WHO and other health authorities have published interim recommendations for care and management of pregnant women and infants during COVID-19 pandemic, many questions remain open. Pregnant women should be considered in prevention and control efforts, including the development of drugs and vaccines against SARS-CoV-2. Further research is needed to confirm the exact impact of COVID-19 infection during pregnancy. To fully quantify this impact, we urgently need to integrate the current knowledge about viral characteristics, epidemiology, disease immunopathology, and potential therapeutic strategies with data from the clinical practice.

20.
Osteoarthritis and Cartilage ; 30:S210, 2022.
Article in English | EMBASE | ID: covidwho-1768338

ABSTRACT

Purpose: The aims of this study were to explore the feasibility and perceived benefits of a remotely delivered Tai Chi mind-body Intervention compared with a wellness education intervention for Knee OA during the COVID-19 pandemic. Methods: In our randomized controlled trial, patients who met the ACR criteria for Knee OA were randomized to either a Tai Chi or Wellness Education group and attended 12 weeks of biweekly remote sessions. Semi-structured interviews were audio and videotaped via Zoom or telephone and ranged from 15-20 minutes in length. Interview questions were designed to ensure the exploration of key themes and were tailored for each intervention. Eleven key themes, including perceived benefits, social interaction and engagement, remote administration, and COVID-19 related experiences were identified and analyzed. Results: Thirty-two patients completed interviews. The mean participant age was 66 years, with 65% female. Consensus suggested remote delivery of the intervention was a well-adapted remedy for Knee OA. Specifically, the Tai Chi group reported pain reduction, improved walking ability;the Wellness group incorporated improved knowledge of healthy living skills into their daily routines. Both groups found therapeutic value in the interventions, such as direct benefits of Tai Chi, and indirect benefits of social interaction during an isolating time. Participants also reported enhanced ability to manage stress surrounding the pandemic. Most interviewees expressed general satisfaction. Several key barriers to treating Knee OA were identified, such as difficulty tailoring instructions to individual patients and providing direct feedback. Conclusions: This study confirmed the feasibility of a remote-delivered behavioral intervention for Knee OA during the pandemic. Despite the challenges of this novel experience, the perceived intervention benefits are comparable to those found in prior, in-person studies. Non-pharmacological methods of treating Knee OA, including remote delivery of education and mind-body approaches, are effective ways of managing Knee OA symptoms.

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