Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 43
Filter
1.
Front Public Health ; 10:981307, 2022.
Article in English | PubMed | ID: covidwho-2023007

ABSTRACT

Internet addiction among the elderly is a novel issue in many countries. However, extant research about excessive use of the Internet is focusing on adolescents and younger adults. There are few studies to explore the topic of the elderly's Internet addiction. The purpose of this study is to investigate the relationship between real-life social support and Internet addiction among older adults during the COVID-19 pandemic. This article adopted a self-reported questionnaire via internet links to collect data. A total of 303 valid samples about Internet addiction for the elderly were obtained in China. The results suggested that real-life social support is significantly and negatively related to Internet addiction among the aged. Moreover, the findings revealed that real-life social support could mitigate Internet addiction by increasing the levels of hopefulness and decreasing the feeling of loneliness. We expect that this study can enrich the understanding of the problematic Internet usage within older populations. Finally, the contributions, practical significance, and limitations of this study were discussed.

2.
Expert Review of Ophthalmology ; : 1-7, 2022.
Article in English | Web of Science | ID: covidwho-2017470

ABSTRACT

Purpose: To evaluate the efficacy and safety of intravitreal dexamethasone (DEX) implantation for diabetic macular edema (DME) that proved unresponsive to previous anti-vascular endothelial growth factor (VEGF) treatment. Methods: This prospective interventional study recruited 91 patients with refractory DME after previous anti-VEGF treatments in one or both eyes. All patients were followed up for at least 12 months. Best-corrected visual acuity (BCVA), central subfield thickness (CST) and macular volume were measured. Results: Over the 12 months, a mean of 2.1 +/- 0.8 DEX implantations were administered per eye;26 eyes (28.9%) received 1 implantation, 31 (34.4%) received 2, and 34 (36.7%) received 3. BCVA was significantly improved in the first 6 months, from 54.8 to 59.5 letters. Both CST and macular volume decreased significantly after DEX implantation and maintained these improvements for at least 12 months. Subjects who needed the second DEX implantation had a greater number of prior anti-VEGF injections than did those who needed only one implantation (6.0 vs 3.0). Conclusions: Two-thirds of refractory DME required less than two DEX implantations to maintain a dry macula for 12 months. Early switching to intravitreal DEX can be considered as the second-line therapeutic option, especially during the COVID-19 pandemic.

3.
Infez Med ; 30(2): 211-222, 2022.
Article in English | MEDLINE | ID: covidwho-1980042

ABSTRACT

Background: Remdesivir (REM) has shown potent antiviral activity in vitro and efficacy in animal models of COVID-19; nevertheless, clinical trials and real-life reports have shown conflicting data on its effectiveness. Aims of the study were to evaluate the impact of remdesivir on I) Intensive Care Unit (ICU) admission, II) need for orotracheal intubation (OTI) and III) in-hospital mortality. Furthermore, we estimated the kinetics of laboratory parameters and assessed the risk factors for in-hospital mortality in the remdesivir population. Methods: We conducted a retrospective, single-center, case-control (1:1) study including hospitalized patients with confirmed SARS-CoV-2 infection. Cases were patients treated with remdesivir for 5 days, controls were patients not receiving remdesivir. Results: A total of 192 patients (96 cases and 96 controls) were included in the study. Patients receiving remdesivir had a lower rate of ICU admission and need for OTI than controls, whereas no difference between cases and controls were observed as for mortality rate. However, at multivariable analysis remdesivir was not associated with ICU admission neither with OTI. Instead, presence of haematological malignancies, lower duration of symptoms, higher severity of infection and low lymphocytes count at admission were independently associated with in-hospital mortality. In patients treated with remdesivir a low albumin value and duration of lymphopenia were significantly associated with mortality. Conclusions: Our real-life study showed that therapy with remdesivir did not have impact on either ICU admission, need for OTI or in-hospital mortality.

4.
International Conference on Intelligent and Fuzzy Systems, INFUS 2022 ; 504 LNNS:831-838, 2022.
Article in English | Scopus | ID: covidwho-1971526

ABSTRACT

With the triggering effect of Covid-19 pandemic, the role of digitalization has become a strategic target and expedited the digital transformation process. World’s direction to the digital future has therefore shaped the use of new-age technologies, such as internet of things, artificial intelligence (AI), machine learning and blockchain. In response to this evolvement of new-age technologies, a noticeable shift from data-driven analysis to technology-oriented applications has occurred, particularly addressing the significance of analytics and AI. These rapid advancements of AI applications influence the use of customer analytics whilst enhancing the importance both for the general understanding and individual behavior of customers, within the scope of customer analytics. Considering the embeddedness of these technologies on practical applications, this study acknowledges the high-impact role and power of AI. In this regard, the study concentrates AI applications from the perspectives of customer analytics. Furthermore, the task of AI, the level of intelligence of AI applications and how the information from customer analytics is obtained and exploited by these applications are discussed. Focusing on the practical case applications, the study suggests a taxonomical structure of AI and customer analytics. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

5.
Eur J Clin Microbiol Infect Dis ; 41(8): 1145-1149, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-1959009

ABSTRACT

Only limited real-life data are available on the effects of neutralizing monoclonal antibodies in high-risk patients who have early COVID-19 and do not require supplemental oxygen. We prospectively studied 217 patients infected by the delta variant who received casirivimab plus indevimab in a dedicated ambulatory unit created during our 4th COVID wave. Mean age was 64 years, 94% had at least one comorbidity, and mean duration of symptoms was 2.9 days. Oxygen requirement, hospitalization, and mortality rates were 10, 6, and 2.8%, respectively. These results suggest benefits of early administration of neutralizing antibodies in high-risk patients infected with the delta variant.


Subject(s)
COVID-19 , Antibodies, Monoclonal, Humanized , COVID-19/drug therapy , Humans , Middle Aged , Oxygen , SARS-CoV-2
6.
Dermatol Ther ; 35(7): e15524, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1956743

ABSTRACT

Recent knowledge on the key role of interleukin (IL) 23/17 axis in psoriasis pathogenesis, led to development of new biologic drugs. Risankizumab is a humanized immunoglobulin G1 monoclonal antibody specifically targeting IL23. Its efficacy and safety were showed by both clinical trials and real-life experiences. However, real-life data on effectiveness and safety of risankizumab in patients who previously failed anti-IL17 are scant. To assess the efficacy and safety of risankizumab in patients who previously failed anti-IL17. A 52-week real-life retrospective study was performed to assess the long-term efficacy and safety of risankizumab in patients who previously failed anti-IL17. A total of 39 patients (26 male, 66.7%; mean age 50.5 ± 13.7 years) were enrolled. A statistically significant reduction of psoriasis area severity index (PASI) and body surface area (BSA) was assessed at each follow-up (PASI at baseline vs. week 52: 13.7 ± 5.8 vs. 0.9 ± 0.8, p < 0.0001; BSA 21.9 ± 14.6 vs. 1.9 ± 1.7, p < 0.0001). Nail psoriasis severity index improved as well, being statistically significative only at week 16 and thereafter [9.3 ± 4.7 at baseline, 4.1 ± 2.4 (p < 0.01) at week 16, 1.4 ± 0.8 (p < 0.0001) at week 52]. Treatment was discontinued for primary and secondary inefficacy in 1(2.6%) and 3(7.7%) patients, respectively. No cases of serious adverse events were assessed. Our real-life study confirmed the efficacy and safety of risankizumab, suggesting it as a valuable therapeutic weapon among the armamentarium of biologics, also in psoriasis patients who previously failed anti-IL17 treatments.


Subject(s)
Antibodies, Monoclonal, Humanized , Psoriasis , Adult , Antibodies, Monoclonal, Humanized/therapeutic use , Female , Humans , Interleukin-23 , Male , Middle Aged , Psoriasis/chemically induced , Psoriasis/diagnosis , Psoriasis/drug therapy , Retrospective Studies , Severity of Illness Index , Treatment Outcome
7.
Vaccines (Basel) ; 10(7)2022 Jun 24.
Article in English | MEDLINE | ID: covidwho-1911714

ABSTRACT

Our investigation aimed to describe the all-cause mortality rates by COVID-19 vaccination groups in Hungary for an epidemic period (1 April 2021-20 June 2021) and a nonepidemic period (21 June 2021-15 August 2021), and to determine the vaccines' effectiveness in preventing all-cause mortality utilizing nonepidemic effectiveness measures to adjust for the healthy vaccinee effect (HVE). Sociodemographic status, comorbidity, primary care structural characteristics, and HVE-adjusted survival difference between fully vaccinated and unvaccinated cohorts in the epidemic period had been computed by Cox regression models, separately for each vaccine (six vaccines were available in Hungary). Hazard ratio (HR) reduction in epidemic period corrected with nonepidemic period's HR with 95% confidence interval for each vaccine was used to describe the vaccine effectiveness (VE). The whole adult population (N = 6,404,702) of the country was followed in this study (4,026,849 fully vaccinated). Each vaccine could reduce the HVE-corrected all-cause mortality in the epidemic period (VEOxford/AstraZeneca = 0.592 [0.518-0.655], VEJanssen = 0.754 [0.628-0.838], VEModerna = 0.573 [0.526-0.615], VEPfizer-BioNTech = 0.487 [0.461-0.513], VESinopharm = 0.530 [0.496-0.561], and VESputnik&nbsp;V = 0.557 [0.493-0.614]). The HVE-corrected general mortality for COVID-19 vaccine cohorts demonstrated the real-life effectiveness of vaccines applied in Hungary, and the usefulness of this indicator to convince vaccine hesitants.

8.
Pharmgenomics Pers Med ; 15: 499-514, 2022.
Article in English | MEDLINE | ID: covidwho-1887051

ABSTRACT

Hereditary transthyretin amyloidosis (ATTRv) is a multisystemic, rare, inherited, progressive and adult-onset disease, affecting the sensorimotor nerves, heart, autonomic function and other organs. The actual scenario of pharmaceutical approaches for ATTRv amyloidosis includes five main groups: TTR stabilizers, TTR mRNA silencers, TTR fibril disruptors, inhibitor of TTR fibril seeding and gene therapy. Patisiran is a small, double-stranded interfering RNA encapsulated in a lipid nanoparticle, able to penetrate into hepatocytes, where it selectively targets TTR mRNA, reducing TTR production. We report and discuss 9 cases of different patients with ATTRv amyloidosis successfully managed with patisiran in the real clinical practice. Literature data, as well as the above presented case reports, show that this drug is effective and safe in improving both neurological and cardiovascular symptoms of ATTRv amyloidosis, and to maintain a good QoL, independently form the stage of the disease and the involved mutation. Recent studies correlated improved functional and biochemical outcomes with a regression of amyloid burden, especially at the cardiac level. Today, patisiran can be considered a valid therapeutic option for the management of patients with ATTRv amyloidosis and polyneuropathy and cardiovascular symptoms.

9.
Diabetes Metab Syndr Obes ; 15: 1737-1747, 2022.
Article in English | MEDLINE | ID: covidwho-1887048

ABSTRACT

Purpose: We aimed to explore the independent factors associated with successful weight loss using a mobile app during the COVID-19 pandemic. Patients and Methods: For this retrospective cohort study, we collected data from 45 adults in a weight loss program using a mobile app. We defined successful weight loss as a weight reduction by ≥ 5% of the baseline weight. Multivariate logistic analysis was used to assess potential factors influencing successful weight loss. Results: All subjects showed a mean 4.1 ± 4.4 kg reduction of baseline weight after using the app for a mean duration of 11 weeks (P < 0.001). Subjects in the successful weight loss group displayed a longer duration of treatment (14.6 ± 6.5 weeks vs 6.9 ± 6.0 weeks, P < 0.001), greater number of dietary records (109.2 ± 84.7 vs 54.7 ± 58.8, P = 0.002), and greater number of outpatient visits (6.1 ± 2.7 vs 3.7 ± 2.3, P < 0.001) than those in the unsuccessful weight loss group. Multivariate logistic analysis showed that duration of treatment was an independent factor associated with successful weight loss (odds ratio = 1.23, 95% confidence interval: 1.08-1.41, P = 0.003). Conclusion: In a weight management program using a mobile app during the COVID-19 pandemic, the duration of treatment was found to be an independent factor of successful weight loss.

10.
Journal of Psychosocial Studies ; 15(1):2-15, 2022.
Article in English | Web of Science | ID: covidwho-1886977

ABSTRACT

Weekly real-life magazines (RLMs) for women form a genre that has experienced sustained popularity for more than three decades and are constructed from claims to represent their readerships' lives. Strikingly, during the COVID-19 pandemic where other magazines have witnessed a decline in sales and many closures, real-life titles have experienced continuous success. This article reads RLMs through a psychosocial lens as a symptom of an emerging social melancholia that began to form from the late 1970s in the United Kingdom. Through an analysis of Chat magazine, the article illustrates how the genre was constructed and argues that it resonates with a form of melancholia that has led to the creation of communities bonded through shared collective experiences that have found the semblance of resolution within this genre's creation.

11.
13th IEEE Global Engineering Education Conference, EDUCON 2022 ; 2022-March:829-835, 2022.
Article in English | Scopus | ID: covidwho-1874212

ABSTRACT

Identifying the connection of theoretical knowledge with real-life problems helps improve learning. This work shows the effect of implementing service-learning using home-labs during COVID-19 crisis in terms student' understanding of theory in practice as well as civic commitment. The obtained results show that service-learning increases student' social justice attitude. Moreover, home labs use improves the connection of theory in practice as well as the willingness to engage in future social work with the community in the context of human factors and ergonomics. © 2022 IEEE.

12.
Education Sciences ; 12(5):355, 2022.
Article in English | ProQuest Central | ID: covidwho-1870630

ABSTRACT

In the past few years, Facebook has been increasingly studied for academic purposes due to its potential benefits to undergraduate education. Problems commonly found in university education include the lack of course engagement and the gap between theory and practice. This research contributes to the literature by investigating the impact of incorporating a non-mandatory Facebook group on learning outcomes. The analysis was done using a Taguchi method design, conducted with three two-level controlled factors (term, Facebook, and teacher). Results indicated that the students who participated in Facebook groups were more engaged with the course and applied theoretical knowledge to real-life problems better than students who learned under traditional instructional designs. Moreover, the use of Facebook groups led to better evaluation of teachers by the students. Furthermore, the student academic impact (knowledge and competence) was higher even though this complementary activity was not included in the course grade. We concluded that Facebook groups are excellent support tools that boost student engagement and their understanding of theoretical concepts and applying them in practice.

13.
International Journal of Innovative Computing, Information and Control ; 18(3):769-781, 2022.
Article in English | Scopus | ID: covidwho-1848055

ABSTRACT

This research article is devoted to Type-II generalized Fermatean bipolar fuzzy soft sets. Type-II generalized Fermatean bipolar fuzzy soft sets approaches are a great point of view for decision making, which is a new generalization of bipolar fuzzy soft sets and generalized fuzzy soft sets. We indicate an algorithm to solve the decision making real life problem based on a soft set model. We discussed the similarity measure between Type-II generalized Fermatean bipolar fuzzy soft sets. Suppose that there are four patients in a hospital with certain symptoms of corona viruses and the universal set contains COVID-19, severe acute respiratory syndrome, middle east respiratory syndrome, usually mild respiratory illness and the set of a parameter is the set of certain symptoms of corona viruses represented by fever, cough, difficulty breathing or shortness of breath, loss of speech or mobility, or confusion and chest pain. Also, we communicate with interact Type-II generalized Fermatean bipolar fuzzy soft sets that can be applied to detecting whether the person is more affecting from a corona disease or not. © 2022 ICIC International.

14.
13th International Conference on E-Education, E-Business, E-Management, and E-Learning, IC4E 2022 ; : 132-137, 2022.
Article in English | Scopus | ID: covidwho-1840625

ABSTRACT

This paper presents the Live Interactive Streaming Classroom (LISC) system model which can be applied to the Problem-Based Learning (PBL) and motivate students to solve problems in a real-life setting with guidance from teachers via online learning. In this study, the students used self-learning methods for interactive class. The class was managed through the online streaming system by the video conference applications. The study showed that the students' coding and real-life problem solving skills were improved from hand-on experience. The LISC system model stimulated students' learning levels. This was proved by applying the proposed method to the Data Science class at Silpakorn University, Thailand, joined by an instructor from Japan. When the course ended, the evaluation from the participating students showed that they were much satisfied that their skills were up-leveled for coding and real-life problem solving, and their attitudes towards the Data Science class improved. It implied and confirmed that the proposed method was efficient to the students' practical learning level, among the new normal living period in the Coronavirus pandemic. © 2022 ACM.

15.
Open Forum Infect Dis ; 9(5): ofac087, 2022 May.
Article in English | MEDLINE | ID: covidwho-1831303

ABSTRACT

Background: Estimating real-world vaccine effectiveness is challenging as a variety of population factors can impact vaccine effectiveness. We aimed to assess the population-level reduction in cumulative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases, hospitalizations, and mortality due to the BNT162b2 mRNA coronavirus disease 2019 (COVID-19) vaccination campaign in Israel during January-February 2021. Methods: A susceptible-infected-recovered/removed (SIR) model and a Dynamic Survival Analysis (DSA) statistical approach were used. Daily counts of individuals who tested positive and of vaccine doses administered, obtained from the Israeli Ministry of Health, were used to calibrate the model. The model was parameterized using values derived from a previous phase of the pandemic during which similar lockdown and other preventive measures were implemented in order to take into account the effect of these prevention measures on COVID-19 spread. Results: Our model predicted for the total population a reduction of 648 585 SARS-CoV-2 cases (75% confidence interval [CI], 25 877-1 396 963) during the first 2 months of the vaccination campaign. The number of averted hospitalizations for moderate to severe conditions was 16 101 (75% CI, 2010-33 035), and reduction of death was estimated at 5123 (75% CI, 388-10 815) fatalities. Among children aged 0-19 years, we estimated a reduction of 163 436 (75% CI, 0-433 233) SARS-CoV-2 cases, which we consider to be an indirect effect of the vaccine. Conclusions: Our results suggest that the rapid vaccination campaign prevented hundreds of thousands of new cases as well as thousands of hospitalizations and fatalities and has probably averted a major health care crisis.

16.
Psychol Med ; : 1-10, 2021 Aug 24.
Article in English | MEDLINE | ID: covidwho-1815417

ABSTRACT

BACKGROUND: It remains unknown whether coronavirus disease 2019 (COVID-19) patients with bipolar disorders (BDs) are at an increased risk of mortality. We aimed to establish whether health outcomes and care differed between patients infected with COVID-19 with BD and patients without a diagnosis of severe mental illness. METHODS: We conducted a population-based cohort study of all patients with identified COVID-19 and respiratory symptoms who were hospitalized in France between February and June 2020. The outcomes were in-hospital mortality and intensive care unit (ICU) admission. We used propensity score matching to control for confounding factors. RESULTS: In total, 50 407 patients were included, of whom 480 were patients with BD. Patients with BD were 2 years older, more frequently women and had more comorbidities than controls without a diagnosis of severe mental illness. Patients with BD had an increased in-hospital mortality rate (26.6% v. 21.9%; p = 0.034) and similar ICU admission rate (27.9% v. 28.4%, p = 0.799), as confirmed by propensity analysis [odds ratio, 95% confidence interval (OR, 95% CI) for mortality: 1.30 (1.16-1.45), p < 0.0001]. Significant interactions between BD and age and between BD and social deprivation were found, highlighting that the most important inequalities in mortality were observed in the youngest [OR, 95% CI 2.28 (1.18-4.41), p = 0.0015] and most deprived patients with BD [OR, 95% CI 1.60 (1.33-1.92), p < 0.001]. CONCLUSIONS: COVID-19 patients with BD were at an increased risk of mortality, which was exacerbated in the youngest and most deprived patients with BD. Patients with BD should thus be targeted as a high-risk population for severe forms of COVID-19, requiring enhanced preventive and disease management strategies.

17.
Dermatol Ther ; 35(4): e15339, 2022 04.
Article in English | MEDLINE | ID: covidwho-1794709

ABSTRACT

Psoriasis is a skin disorder characterized by chronic inflammation driven by different immunologic pathways, among which the IL-23/Th17 axis plays a pivotal role. For this reason, the use of IL23p19 inhibitors in psoriasis treatment has been evaluated over the years. Guselkumab, a totally human IgG1 lambda monoclonal antibody, that selectively blocks the p 19 subunit of IL- 23 has demonstrated high efficacy and safety throughout several, randomized, double-blind phase III trials (VOYAGE 1 and 2, NAVIGATE and ECLIPSE). We designed a single-center retrospective cohort study in a population consisting of 46 patients followed from December 2018 to April 2021. After a diagnosis of moderate to severe psoriasis, all the patients were considered suitable to receive treatment with Guselkumab. In our population, among those who achieved clinical improvement in terms of Psoriasis Area Severity Index (PASI), PASI 75, 90, and 100 were achieved on average on weeks 14, 19, 21 respectively. We then analyzed a subgroup of our population, consisting of 35 patients, who had an identical follow-up time of 28 weeks, thus observing the trend in mean PASI at subsequent assessments and the number of patients who had reached PASI 75, PASI 90, and PASI 100 at week 4 (10; 3; 1), week 12 (12; 13; 11), week 20 (7; 6; 2), and week 28 (1; 4; 6), respectively. The results obtained are in line with those obtained from previous studies, thus confirming that Guselkumab is an excellent choice in terms of security, long-term efficacy, and overall tolerance.


Subject(s)
Psoriasis , Antibodies, Monoclonal, Humanized , Clinical Trials, Phase III as Topic , Double-Blind Method , Humans , Psoriasis/diagnosis , Psoriasis/drug therapy , Randomized Controlled Trials as Topic , Retrospective Studies , Severity of Illness Index , Treatment Outcome
18.
Journal of Internationalization and Localization ; 8(2):110-136, 2021.
Article in English | Scopus | ID: covidwho-1788370

ABSTRACT

In this paper we describe how a COVID-19 phone app was localized by students of the MA program in Translation and Interpreting at the University of Illinois at Urbana-Champaign. The project presented unique challenges including the urgency and short time-lines, less-than-optimal internationalization of the source code, limitations of the CAT tool, and the use of an open-source platform and crowd-sourced agile development model, in addition to particular linguistic aspects related to the new specialized subject matter, limited string context, and potentially sensitive data. On the other hand, it offered the opportunity to experience a real-life localization project, which had important pedagogical benefits for translation students. These and other aspects are described and suggestions proposed to enable similar projects to run smoothly. © John Benjamins Publishing Company.

19.
14th International Conference on Developments in eSystems Engineering, DeSE 2021 ; 2021-December:469-474, 2021.
Article in English | Scopus | ID: covidwho-1769563

ABSTRACT

The paper suggests a machine learning algorithm with two modified SEIR models customized for the 2019-nCoV virus and vaccine uses to simulate the spread of COVID-19 in the UK (from Jan 2020 to March 2021) and make predictions of future cases. The algorithm uses COVID daily cumulative case data and second dose vaccine use data provided by the Public Health England as the training set and is capable of making relatively accurate short-term predictions of future COVID cases in the UK (before the delta and later variants of the virus starts spreading within the country). The obtained overall accuracy is above 80% for daily incremental case numbers in terms of the overall fit of the model to real-life data, and with an accuracy of more than 80% for estimation of daily incremental case numbers for 14 days period future prediction. The goal of this paper is to propose improved SEIR models capable of a more accurate simulation for COVID-19 modelling and estimation with various machine learning algorithms. © 2021 IEEE.

20.
15th European Conference on Game Based Learning (ECGBL) ; : 925-928, 2021.
Article in English | Web of Science | ID: covidwho-1744353

ABSTRACT

During the last decade, escape rooms have become a popular place of amusement. Escape the Room is best described as a combination of LARP (Live Action Role Play), scavenger hunt, and Sherlock Holmes. The players are immersed in a scenario and have a set amount of time to solve a variety of puzzles using the materials and information provided to move from one room to the next until they can finally leave the building. While escape rooms are mainly deployed for team-building activities or entertainment, there are further fields of application. In an interdisciplinary project at Johannes Kepler University Linz, we adapted escape rooms for educational purposes. The Institute of Business Informatics - Software Engineering and the School of Education developed three escape room games designed to impart the principles of computer science to a younger audience in a fun way. The players can select a board game, a computer game, or a real-life game, each with its unique story, puzzles, and hints. The game variants focus on computer science but can be expanded and adapted to other subjects. As all the constructions and puzzles show a flexible design, they can be adapted to the educational level of the respective target group (primary level, secondary I + II, teacher training, and university courses) and abilities of students. Each game contains additional bonus material for experienced players. Due to the COVID-19 pandemic, the test phase of all three escape room game variants was postponed but is planned to continue in autumn 2021.

SELECTION OF CITATIONS
SEARCH DETAIL