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1.
Nobel Medicus ; 18(2):116-124, 2022.
Article in Turkish | Scopus | ID: covidwho-2027008

ABSTRACT

Objective: It was aimed to adapt the Lockdown Fatigue Scale into Turkish and to analyze the psychometric properties of the scale. Material and Method: The research was carried out with 368 people aged 18 and over, whose consent was taken. Personal information form, Lockdown Fatigue Scale and Chalder Fatigue Scale were used to collect data. In the evaluation of the data, explaratory and confirmatory factor analysis for structure validity, Cronbach alpha and item test-retest were used to ensure reliability. Mann-Whitney U-test and Kruskal-Wallis test were used to compare the scores obtained in the scale according to psychometric properties. Results: The Cronbach's alpha value of the 5-point Likert-type, single-factor, 10-item scale was found to be 0.91. The total variance explained by the factor regarding the scale is 56.36%, the content validity index is 0.90, and the test-retest reliability value is 0.85. The correlation between the adapted scale and the Chalder Fatigue Scale was 0.75. Item factor loads varied between 0.493 and 0.884. The participants' mean scores on the scale were 30.91±9.48, and they had high fatigue. In addition, 1.3% of the participants had low, 29.6% moderate, 39.9% high, 29.2% severe fatigue. The scale score differed according to the participants' gender (p<0.001), marital status (p<0.001), having COVID-19 (p=0.006), place of residence (p=0.031), educational status (p=0.007), and usual compared with the current state of fatigue (p<0.001). Conclusion: The Turkish version of the Lockdown Fatigue Scale is a valid and reliable for measuring the fatigue caused by the pandemic-related closure in individuals aged eighteen and older. © 2022, Nobelmedicus. All rights reserved.

2.
Iranian Journal of Psychiatry and Behavioral Sciences ; 15(4), 2021.
Article in English | Scopus | ID: covidwho-2025222

ABSTRACT

Background: One of the most common mental health-related issues related to the COVID-19 pandemic is high levels of distress and anxiety due to the COVID-19 pandemic. Psychological well being and conservation of the general population are utterly significant components of facing COVID-19 pandemic. It seems that despite the availability of highly standardized tools to investigate COVID-19-related anxiety, the Coronavirus Anxiety Scale (CAS) can be helpful in different populations due to its short design. Objectives: The present study aimed to assess the psychometric properties of the Persian (Iranian) version of the Coronavirus Anxiety Scale (P-CAS). Methods: In this web-based cross-sectional study, 305 individuals (184 females vs. 121 males) participated. All participants were evaluated by five questionnaires, including the P-CAS, COVID Stress Scales (CSS), the Depression, Anxiety and Stress Scale-21 (DASS-21), Whiteley index (WI), and Difficulties in Emotion Regulation Scale (DERS). Cronbach’s alpha, confirmatory factor analysis (CFA), and correlation coefficient were used for data analysis using SPSS 23 and AMOS-23 software. Results: The results of CFA demonstrated that the factor structure of the P-CAS was good, and the scale had an appropriate internal consistency (α = 0.80). A satisfactory convergent validity was shown due to positive correlations of the P-CAS with the related scales. Test-retest reliability of P-CAS was also satisfactory (ICC = 0.95). Conclusions: According to our results, the P-CAS is a valid and reliable instrument to evaluate the severity of dysfunctional anxiety due to COVID-19 pandemic. © 2021, Author(s).

3.
International Journal of Data and Network Science ; 6(4):1631-1642, 2022.
Article in English | Scopus | ID: covidwho-2025109

ABSTRACT

E-consumer rights aim to provide consumers and sellers a fair opportunity when dealing online, which requires both parties to know their rights and ethics. Therefore, the purpose of this study is to verify the impact of consumer rights available on reputed online store websites in Saudi Arabia (KSA) on the customer service, using expectation confirmation theory (ECT). A random sampling technique was used for primary data collection from a sample size of 152 faculty members. IBM Software Package for Social Sciences SPSS-26 and structural equation modeling (SEM) LISREL software programs were used for data analysis. The findings show that e-consumer rights have positive and significant effects on customers’ e-reliability and e-responsiveness. In addition, consumers’ income significantly influences their e-responsiveness, while the number of e-dealings per month significantly influences both e-reliability and e-responsiveness. The results of the study also provide an inventory of eight reasons why consumers prefer to deal with local electronic stores over foreign ones. Based on these findings, theoretical importance, practical implications, and suggestions for future research are discussed. © 2022, Growing Science. All rights reserved.

4.
Pathogens ; 11(8):938, 2022.
Article in English | ProQuest Central | ID: covidwho-2023973

ABSTRACT

Background. Nowadays, most of the C. parvum and C. hominis epidemiological studies are based on gp60 gene subtyping using the Sanger sequencing (SgS) method. Unfortunately, SgS presents the limitation of being unable to detect mixed infections. Next-Generation Sequencing (NGS) seems to be an interesting solution to overcome SgS limits. Thus, the aim of our study was to (i) evaluate the reliability of NGS as a molecular typing tool for cryptosporidiosis, (ii) investigate the genetic diversity of the parasite and the frequency of mixed infections, (iii) assess NGS usefulness in Cryptosporidium sp. outbreak investigations, and (iv) assess an interpretation threshold of sequencing data. Methods. 108 DNA extracts from positive samples were sequenced by NGS. Among them, two samples were used to validate the reliability of the subtyping obtained by NGS and its capacity to detect DNA mixtures. In parallel, 106 samples from French outbreaks were used to expose NGS to epidemic samples. Results. NGS proved suitable for Cryptosporidium sp. subtyping at the gp60 gene locus, bringing more genetic information compared to SgS, especially by working on many samples simultaneously and detecting more diversity. Conclusions. This study confirms the usefulness of NGS applied to C. hominis and C. parvum epidemiological studies, especially aimed at detecting minority variants.

5.
International Journal of Environmental Research and Public Health ; 19(17):10965, 2022.
Article in English | ProQuest Central | ID: covidwho-2023715

ABSTRACT

Emotional Eating (EE) patterns have been shown to play a relevant role in the development of overweight and obesity. The aim of this study was to analyze the factor structure and psychometric properties of the Emotional Eater Questionnaire (EEQ) in university students from Huelva. The EEQ was administered to 1282 students (age 22.00 (±5.10), BMI 23.59 (±6.74)), belonging to the University of Huelva. An exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were carried out. The internal structure of the questionnaire, internal consistency, test-retest reliability, and convergent validity were analyzed. Principal component analysis of the questionnaire showed two dimensions, explaining 56% of the variance. Internal consistency showed a Cronbach’s alpha of 0.859 globally, and of 0.841–0.855 if the items were removed. The corrected item-total correlation yielded values of 0.444–0.687. The test-retest stability was ICC = 0.924 (p < 0.001). The data showed significant correlations between EEQ and the rest of the variables, and a Spearman’s Coefficient ranging from −0.367 to 0.400. The fit indexes were good for the confirmatory factor analysis. The results obtained with this structure found an adequate reliability and validity of the questionnaire in comparison with previous studies.

6.
Front Nutr ; 9:949330, 2022.
Article in English | PubMed | ID: covidwho-2022813

ABSTRACT

BACKGROUND: The Young Lives longitudinal study switched to remote data collection methods including the adaptation of dietary intake assessment to online modes due to the physical contact restrictions imposed by the COVID-19 pandemic. This study aimed to describe the adaptation process and validation of an online quantitative food frequency questionnaire (FFQ) for Peruvian young adults. METHODS: A previously validated face-to-face FFQ for the adult Peruvian population was adapted to be administered through an online self-administered questionnaire using a multi-stage process. Questionnaire development was informed by experts' opinions and pilot surveys. FFQ validity was assessed by estimating misreporting of energy intake (EI) using the McCrory method, and the FFQ reliability with Cronbach alpha. Logistic regressions were used to examine associations of misreporting with sociodemographic, body mass index (BMI), and physical activity covariates. RESULTS: The FFQ was completed by 426 Peruvian young adults from urban and rural areas, among whom 31% were classified as misreporters, with most of them (16.2%) overreporting daily EI. Men had a lower risk of under-reporting and a higher risk of over-reporting (OR = 0.28 and 1.89). Participants without a higher education degree had a lower risk of under-reporting and a higher risk of over-reporting (OR = 2.18 and 0.36, respectively). No major difference in misreporting was found across age groups, areas, studying as the main activity, being physically active or sedentary, or BMI. Results showed good internal reliability for the overall FFQ (Cronbach alpha = 0.82). CONCLUSION: Misreporting of EI was mostly explained by education level and sex across participants. Other sociodemographic characteristics, physical activity, sedentary behavior, and BMI did not explain the differences in EI misreporting. The adapted online FFQ proved to be reliable and valid for assessing dietary intakes among Peruvian young adults during the COVID pandemic. Further studies should aim at using and validating innovative dietary intake data collection methods, such as those described, for informing public health policies targeting malnutrition in different contexts after the COVID-19 pandemic.

7.
Journal of Korean Medical Science ; 37(34), 2022.
Article in English | Web of Science | ID: covidwho-2022639

ABSTRACT

Background: This study aimed to investigate the effects of comprehensive rehabilitation management on functional recovery and examine the correlation between clinical parameters and improvements in functional outcomes in severe-to-critical inpatients with coronavirus disease 2019 (COVID-19) in a tertiary hospital. Methods: Post-acute COVID-19 patients who had a World Health Organization (WHO) ordinal scale of 5-7, underwent intensive care, and received comprehensive rehabilitation management, including exercise programs, nutritional support, dysphagia evaluation, and psychological care were included. The appendicular skeletal muscle mass index (SMI), Medical Research Council sum score, handgrip strength, number of repetitions in the 1-minute sit-to-stand test, gait speed, Berg Balance Scale (BBS), and Functional Ambulation Classification (FAC) were evaluated at hospital stay, discharge, and 1-month follow-up. The correlation between the rehabilitation dose and improvement in each outcome measure was analyzed. Results: Overall, 37 patients were enrolled, of whom 59.5% and 32.4% had a score of 6 and 7 on the WHO ordinal scale, respectively. Lengths of stay in the intensive care unit and hospital were 33.6 +/- 23.9 and 63.8 +/- 36.5 days. Outcome measures revealed significant improvements at discharge and 1-month follow-up. The SMI was significantly increased at the 1-month follow-tip (6.13 [5.24-7.76]) compared with that during the hospital stay (5.80 [5.39-7.05]). We identified dose-response associations between the rehabilitation dose and FAC (rho = 0.46) and BBS (rho = 0.50) scores. Patients with older age, longer hospitalization, longer stay at the intensive care unit, longer duration of mechanical ventilation, tracheostomy, a more depressive mood, and poorer nutritional status revealed poorer improvement in gait speed at the 1-month follow-up. Conclusion: Comprehensive rehabilitation management effectively improved muscle mass, muscle strength, and physical performance in severe-to-critical COVID-19 patients. Dose-response relationship of rehabilitation and functional improvement emphasizes the importance of intensive post-acute inpatient rehabilitation in COVID-19 survivors.

8.
PLoS One ; 17(9), 2022.
Article in English | ProQuest Central | ID: covidwho-2021968

ABSTRACT

Background Telehealth could enhance rehabilitation for people with chronic health conditions. This review examined the psychometric properties of performance-based measures of physical function administered via telehealth among people with chronic health conditions using the Consensus-Based Standards for the Selection of Health Measurement Instruments (COSMIN) approach. Methods This systematic review was registered with Prospero (Registration number: CRD42021262547). Four electronic databases were searched up to June 2022. Study quality was evaluated by two independent reviewers using the COSMIN risk of bias checklist. Measurement properties were rated by two independent reviewers in accordance with COSMIN guidance. Results were summarised according to the COSMIN approach and the modified GRADE approach was used to grade quality of the summarised evidence. Results Five articles met the eligibility criteria. These included patients with Parkinson’s Disease (n = 2), stroke (n = 1), cystic fibrosis (n = 1) and chronic heart failure (n = 1). Fifteen performance-based measures of physical function administered via videoconferencing were investigated, spanning measures of functional balance (n = 7), other measures of general functional capacity (n = 4), exercise capacity (n = 2), and functional strength (n = 2). Studies were conducted in Australia (n = 4) and the United States (n = 1). Reliability was reported for twelve measures, with all twelve demonstrating sufficient inter-rater and intra-rater reliability. Criterion validity for all fifteen measures was reported, with eight demonstrating sufficient validity and the remaining seven demonstrating indeterminate validity. No studies reported data on measurement error or responsiveness. Conclusions Several performance-based measures of physical function across the domains of exercise capacity, strength, balance and general functional capacity may have sufficient reliability and criterion validity when administered via telehealth. However, the evidence is of low-very low quality, reflecting the small number of studies conducted and the small sample sizes included in the studies. Future research is needed to explore the measurement error, responsiveness, interpretability and feasibility of these measures administered via telehealth.

9.
5th International Conference on Big Data and Education, ICBDE 2022 ; : 387-392, 2022.
Article in English | Scopus | ID: covidwho-2020384

ABSTRACT

The COVID-19 pandemic imposes a tremendous burden upon society. Several studies have documented stressors and fears of COVID-19 for adult populations, but few studies pay attention to the COVID-19 stressors on children and adolescents. Assessing the stressors of COVID-19 on children and adolescents can provide the basis for interventions to bring children and adolescents' mental health "out of the shadows."Entering the Era of "Big Data,"the psychological state can be assessed through integrative analysis of data. This study adopted a whole-group sampling method. After a new round of the COVID-19 epidemic caused by imported cases in Jiangsu and Fujian provinces of China, self-report questionnaires were sent to children and adolescents aged 10-18 years. 1815 valid questionnaires were collected. Data analysis was performed using SPSS and AMOS software (version 26). To revise and test the reliability and validity of the COVID-19 stressors scale for children and adolescents, as well as to investigate the differences in stressors between rural and urban based on Big-Data Mining. The results of this study indicate that the revised COVID-19 stressors scale, which includes a four-factor model of disease stressors, information stressors, measure stressors, and environmental stressors, has good reliability and validity for children and adolescents aged 10-18 years in a Chinese context. Big data-based demographic analysis showed that children and adolescents living in urban areas were generally less stressed about the COVID-19 epidemic than in rural areas. © 2022 Owner/Author.

10.
Int J Methods Psychiatr Res ; : e1912, 2022 Jun 09.
Article in English | MEDLINE | ID: covidwho-2013687

ABSTRACT

OBJECTIVE: While polysubstance use is highly prevalent among people who use drugs, the field lacks a reliable assessment that can detect detailed temporal patterns of polysubstance use. This study assessed the test-retest reliability of the newly developed Polysubstance Use-Temporal Patterns Section (PSU-TPS). METHODS: Participants who used cocaine plus alcohol and/or marijuana at least once in the past 30 days (n = 48) were interviewed at baseline and approximately 7 days later (retest) using the Substance Abuse Module and the PSU-TPS. Reliability of PSU-TPS measures of quantity, frequency, and duration of polysubstance use was examined using intra-class correlation coefficients (ICCs) and kappa tests. RESULTS: Excellent reliability was observed for frequencies of concurrent polysubstance use patterns in the past 30 days (ICC range: 0.90-0.94) and quantity of alcohol use (ICC = 0.83), and fair to good reliability was observed for duration of substance use (ICC range: 0.52-0.73). CONCLUSION: Detailed information regarding cocaine, alcohol, and marijuana polysubstance use in the past 30 days can be reliably measured with the PSU-TPS. Data on the order and timing of polysubstance use at the hourly level will improve our understanding of the implications of sequential and simultaneous use patterns, which can help inform treatment and prevention efforts.

11.
Scientific Reports ; 12(1), 2022.
Article in English | Web of Science | ID: covidwho-2016835

ABSTRACT

Temporomandibular disorders (TMD) are a multifactorial condition associated with both physical and psychological factors. Stress has been known to trigger or worsens TMD. We aimed to investigate whether the novel coronavirus disease-2019 (COVID-19) pandemic aggravates depression in patients with painful TMD, and the factors that affect their level of depression. We included 112 patients with painful TMD (74 females, 38 males;mean age: 35.90 +/- 17.60 years;myalgia [n = 38], arthralgia [n = 43], mixed joint-muscle TMD pain [n = 31]). TMD was diagnosed based on the Diagnostic Criteria for TMD Axis I. Physical pain intensity was recorded using the visual analog scale (VAS);psycho-emotional status (depression: Beck Depression Inventory [BDI], anxiety: Beck Anxiety Inventory [BAI], and generalized stress related to COVID19: Global Assessment of Recent Stress [GARS]) was investigated twice (before [BC] and after COVID-19 [AC]). Additionally, factors affecting BDI-AC were investigated. BDI (p < 0.001), BAI (p < 0.001), GARS (p < 0.001), and VAS (p < 0.01) scores were significantly increased at AC than BC. The depression, anxiety, and stress levels were significantly positively correlated, and the AC and BC values of each factor showed a high correlation. In the mixed TMD group, BDI-AC was positively correlated with VAS-AC (p < 0.001). In the multiple regression analysis, clenching habit was the strongest predictor of an increase in the BDI scores from moderate to severe, followed by psychological distress, muscle stiffness, female sex, BAI-AC, and TMJ sounds. COVID-19 has negatively affected the psycho-emotional state of patients with painful TMD, and several clinical factors, including female sex and clenching habits, have influenced depression.

12.
Natural Language Engineering ; : 1-23, 2022.
Article in English | Web of Science | ID: covidwho-2016483

ABSTRACT

Cyberbullying is the wilful and repeated infliction of harm on an individual using the Internet and digital technologies. Similar to face-to-face bullying, cyberbullying can be captured formally using the Routine Activities Model (RAM) whereby the potential victim and bully are brought into proximity of one another via the interaction on online social networking (OSN) platforms. Although the impact of the COVID-19 (SARS-CoV-2) restrictions on the online presence of minors has yet to be fully grasped, studies have reported that 44% of pre-adolescents have encountered more cyberbullying incidents during the COVID-19 lockdown. Transparency reports shared by OSN companies indicate an increased take-downs of cyberbullying-related comments, posts or content by artificially intelligen moderation tools. However, in order to efficiently and effectively detect or identify whether a social media post or comment qualifies as cyberbullying, there are a number factors based on the RAM, which must be taken into account, which includes the identification of cyberbullying roles and forms. This demands the acquisition of large amounts of fine-grained annotated data which is costly and ethically challenging to produce. In addition where fine-grained datasets do exist they may be unavailable in the target language. Manual translation is costly and expensive, however, state-of-the-art neural machine translation offers a workaround. This study presents a first of its kind experiment in leveraging machine translation to automatically translate a unique pre-adolescent cyberbullying gold standard dataset in Italian with fine-grained annotations into English for training and testing a native binary classifier for pre-adolescent cyberbullying. In addition to contributing high-quality English reference translation of the source gold standard, our experiments indicate that the performance of our target binary classifier when trained on machine-translated English output is on par with the source (Italian) classifier.

13.
Behaviour Change ; : 1-12, 2022.
Article in English | Web of Science | ID: covidwho-2016376

ABSTRACT

Objective: To provide a quantitative assessment of the literature examining the cross-sectional association between loneliness and depressive symptoms in children and adolescents. Method: A total of 44 studies from 35 articles (n = 27, 214;mean age 13.63 years;51% female) met inclusion criteria. Results: A medium, positive correlation between loneliness and depressive symptoms in children and adolescents was found (r = .48). Age and gender did not moderate the relationship between loneliness and depressive symptoms. Conclusion: Loneliness may be a particular risk factor for depression. These results have implications for COVID-19 disease containment measures.

14.
Neonatology Today ; 17(8):3-19, 2022.
Article in English | CINAHL | ID: covidwho-2012886

ABSTRACT

The interest in wearable wireless monitoring systems has accelerated secondary to the ongoing COVID-19 pandemic. Moreover, the alarmingly high number of infections in the pediatric population underscores a gap in monitoring these vulnerable populations, particularly in the home setting. This systematic review aims to identify and assess currently available wearables used to monitor cardiopulmonary function in infants and neonates. The study, prospectively registered on PROSPERO (CRD42020200642), completed a search of PubMed 1946-, Embase 1947-, Cochrane Library, Scopus 1823-, and IEEE Explore 1872-in June 2020. A total of 2324 unique citations were identified, with 16 studies describing 17 unique devices meeting inclusion criteria. Types of devices included smart clothing, belts, and mechanical adhesives, each with unique battery designs, data collection, and transmission hardware. Only four of the 17 devices underwent rigorous comparative testing, and three demonstrated correlation with the standard of care monitoring systems. Low sensitivity and specificity were reported in two commercially available consumer devices compared to the standard of care monitoring systems. The risk of bias in the entire cohort was highly based on a modified ROBINS-I scale. Further development and rigorous wearable device testing are necessary for neonatal and infant deployment.

15.
Acta bio-medica : Atenei Parmensis ; 93(4):e2022287, 2022.
Article in English | MEDLINE | ID: covidwho-2010583

ABSTRACT

BACKGROUND AND AIM: Interprofessional collaboration (IPC) between health professionals is fundamental for the provision of an efficient and effective medical care service. This is especially so in states of emergency, as highlighted by the ongoing coronavirus disease 2019 pandemic. This study aimed to obtain further evidence regarding the validity and reliability of the Italian language IPC scale -an instrument for measuring interprofessional collaboration- in a setting that has yet to be investigated at an in-depth level: the emergency departments in Italian hospitals. METHODS: The survey tool was a structured questionnaire in the Italian language. It comprised the validated Italian version of the IPC scale plus a question concerning the frequency of collaborations between the nurses interviewed and other health professionals. Confirmatory factor analysis was applied to rate the three factors ("communication", "accommodation" and "isolation") that compose the scale. RESULTS: Four hundred thirty-six nurses working in an emergency department for at least one year completed the questionnaire, which assessed collaboration with other health professionals working in the same department. The model fit statistics are satisfactory for all the nurse-target group combinations analysed. Regarding the Cronbach's alpha statistic used to compute the reliability of the scale, acceptable values were obtained for all items, except for those related to the isolation factor for each case of interprofessional collaboration considered. CONCLUSIONS: The results confirm the validity of the IPC scale as an instrument for the assessment of interprofessional collaboration involving nurses and other workers occupied in the provision of healthcare in Italian emergency departments.

16.
NeuroQuantology ; 20(8):7077-7083, 2022.
Article in English | EMBASE | ID: covidwho-2010525

ABSTRACT

This paper describes the perception of school teachers of Aurangabad city towards teaching using the Open-Source Learning Management System (LMS) MOODLE in teaching science subjects. The Free and Open-Source (LMS) MOODLE has brought a dynamic pedagogical shift in Online Learning due to its nature of robust features and free availability. The outbreak of COVID-19 has forced formal and non-formal educational systems to adopt an Online teaching-learning platform for the transaction of information. In this study, teachers’ perception of using LMS-MOODLE in teaching science to secondary school students of Aurangabad city is studied. The research methodology adopted is the descriptive survey method, and the sample consists of 40 female and 45 male teachers of secondary school students of Aurangabad. In this research, a self-made perception scale (refer to appendix) is prepared with a 5-point Likert-type scale, the reliability of the test found by Cronbach (0.71). The data analysis shows that the perception among female and male school teachers of Aurangabad city, [U = 766.5, p =.23] in teaching science using LMS-MOODLE is almost the same. Further, the perception between groups, i.e., primary and secondary school teachers of Aurangabad city, [U = 878.5, p =.898] towards using LMS-MOODLE in teaching science was also found to be identical. The study results suggest that female and male school teachers have similar perceptions towards teaching science subjects by using LMS-MOODLE.Similarly, primary and secondary school teachers have identical perceptions towards teaching science subjects by using LMS-MOODLE. The most plausible reason for the similar perceptions among male and female teachers at the primary and secondary levels is the application of the Internet and technology in learning and teachingduring the pre-COVID-19 and post-COVID-19 pandemics and the social distancing implemented by the authority.

17.
Frontiers in Genetics ; 13, 2022.
Article in English | EMBASE | ID: covidwho-2009857

ABSTRACT

Aims: The causal relationship between COVID-19 infection and stroke has not yet been fully established. This study aimed to explore this causality using two-sample Mendelian randomization (MR). Materials and Methods: Genetic variants associated with COVID-19 infection and stroke were both obtained from genome-wide association study (GWAS) summary data. The single nucleotide polymorphisms (SNPs) were selected as instrumental variables. The standard inverse variance weighted (IVW) was primarily used to assess this causality. Finally, sensitivity analysis was performed to evaluate the reliability and stability. Results: The results showed that being hospitalized due to COVID-19 had a positive effect on stroke [OR = 1.05;95% CI= (1.01, 1.10);p = 2.34 × 10−5] and ischemic stroke [OR = 1.06;95% CI= (1.02, 1.11);p = 2.28 × 10−6] analyzed by inverse variance weighted. Moreover, the results revealed that severe respiratory symptoms due to COVID-19 had a positive effect on stroke [OR = 1.04;95% CI= (1.00, 1.06);p = 0.04] and that the causal effect of severe respiratory symptoms due to COVID-19 on ischemic stroke estimated by IVW suggested a positive effect [OR = 1.06;95% CI= (1.02, 1.09);p = 0.0068], too. Conclusion: In summary, this study showed that severe COVID-19 might increase the risk of stroke, thus much more attention should be paid to patients with severe COVID-19.

18.
Annals of the Rheumatic Diseases ; 81:201-202, 2022.
Article in English | EMBASE | ID: covidwho-2009143

ABSTRACT

Background: Has the COVID-19 crisis overwhelmed health democracy? This question may have arisen since extraordinary measures taken in response to the pandemic were developed almost exclusively by Scientific expert committees. Citizens, patients, patient organizations, healthcare professionals, and even experts from these committees have recognized a lack of health democracy in the decision-making process regarding the COVID-19 response in France. Indeed, patient voices were barely heard during the early stages of the pandemic;yet inclusive dialogue is crucial for building trust and adherence to policy. Moreover, patients also need to be assisted in handling the overabundance of COVID-19 information, particularly misleading and false information, referred to as an 'infodemic' by the WHO. Objectives: To show a practical and effective application of health democracy in rheumatology through collaboration between patient associations and rheu-matologists during the COVID-19 pandemic. To collect, select, analyze, , and translate COVID-19 literature to provide rheumatoid arthritis (RA) patients with useful, convenient and quality educational materials that answer patients' medical, Scientific and daily life questions. This initiative is consistent with patient-centered COVID-19 response. Methods: At the instigation of a patient association in October 2021, a working group was established to develop a COVID-19 patient education resource to meet the expectations and needs of RA patients. The working group consisted of health professionals and patients identifed by the partner patient organization. A committee of rheumatologists checked the reliability and accuracy of the Scientific and medical information. A committee of patients assessed materials' relevance, readability, and understandability. Materials were written in lay language without distorting the meaning of the Scientific data. The methodology is detailed in Figure 1. Results: The document is available to download on www.polyarthrite-andar.com (number of unique visits on the webpage for the last version: 1176). A printed version was also provided directly to patients by rheumatologists. To provide up-to-date information, the brochure was updated 7 times between the frst edition in January 2021 and the last version in August 2021. This last version included 49 questions. Each update was announced to all members of the patient organization in its monthly newsletter (number of newsletter's subscribers: 1863;number of followers: Face-book=2632;Twitter=1382;Instagram=921;LinkedIn= 590;Youtube=2907). The 'Medical and Scientific questions' section provided reliable and expert-reviewed information about the virus, protective measures, testing, vaccination, integrating RA specifcities and its treatments for each item. The 'Daily life questions' section provided practical advice during the pandemic, in particular by addressing the 'TousAntiCovid' smart-phone application, isolation certifcates, remote working and lockdown instructions. Conclusion: This initiative demonstrates the benefts that can be achieved by greater collaboration between patients and healthcare professionals to address population health problems. The patient could be an active contributor in improving disease management of his peers. This patient education tool is a good example of the relevance of the motto of 'nothing about us, without us.' The COVID-19 pandemic has highlighted the importance of bringing patients' voices to affect evidence-based policies centered around the needs of patients. Health democracy needs to form the backbone of how a health system is structured.

19.
Annals of the Rheumatic Diseases ; 81:924-925, 2022.
Article in English | EMBASE | ID: covidwho-2008820

ABSTRACT

Background: Due to the pleiotropic cytokine interleukin-6 (IL-6) plays a pivotal role in the pathogenesis of COVID-19, tocilizumab, an inhibitor of the IL-6 receptors, was considered as an attractive therapeutic option. When the infamma-tion cascade is excessive and therapy is delayed, the efforts for suppression of infammation does not necessarily reduce mortality in all cases. Besides, early using anti-cytokine therapy may lead to both increased cost and risks including iatrogenic immunosuppression (1). Defning of patients who will beneft from tocilizumab and determining optimal timing of tocilizumab will prevent drug-related side effects and increased costs due to unnecessary drug use. Objectives: To investigate the reliability of pre-treatment levels of prognostic nutritional index (PNI), C-reactive protein/albumin ratio (CAR), systemic immune-in-fammatory index (SII), IL-6, lactate dehydrogenase (LDH) as a treatment response biomarker in hospitalized COVID-19 patients who administered tocilizumab. Methods: One hundred thirty three COVID-19 patients received tocilizumab were included. The end-points of treatment effectiveness were evaluated with the rate of death and emerging need for mechanical ventilation at 28 days of hospitalization. To determine independent mortality risk factors, multivariate logistic regression analyzes were performed for statistically different variables among groups that were statistically different in univariate analysis. The capacity of IL-6, CAR, PNI, SII and LDH values in predicting of tocilizumab response in COVID-19 patients were analyzed using receiver operating characteristic (ROC) curve analysis. Results: 34 (25.56%) patients died after tocilizumab therapy. Patients who improved after tocilizumab were signifcantly younger and had signifcantly lower IL-6, LDH, SII, CAR and higher PNI than patients who died. In univariate analyses, mortality was signifcantly associated with age, IL-6, LDH, PNI, SII, CAR and CRP. In multivariate analysis, age (OR:1.070, 95%CI:1.019-1.124, p:0.007) and LDH (OR:1.006, 95CI%:1.003-1.010, p<0.001) were found to be independent predictors of mortality after tocilizumab therapy. To identify of tocilizumab response in COVID-19 patients, IL6 had the highest area under curve (AUC) value (AUC:0.782, 95%CI:0694-0.870), followed by LDH (AUC:0.761, 95%CI:0.661-0.861), PNI (AUC:0.696, 95%CI:0.584-807), SII (AUC:0.671, 95%CI:0.551-0.790), CAR (AUC:0.682, 95%CI:0.578-0.786) and CRP (AUC:0.643, 95%CI:0.535-0.751). Predictive performance of infammatory biomarkers in the prediction of mortality after tocilizumab therapy was presented in Table 1. Conclusion: Although the patients with signifcantly lower IL-6, LDH, SII, CAR and higher PNI levels improved after tocilizumab therapy, only serum LDH levels and age were found to be as independent predictors of mortality. To specify the optimal time interval and the patients who will beneft from tocilizumab, these biomarkers may be used.

20.
Revista de Psiquiatría y Salud Mental ; 2022.
Article in English | ScienceDirect | ID: covidwho-2008096

ABSTRACT

Resumen Este trabajo de revisión analiza el estado de los conocimientos sobre la Telepsiquiatría (TP) tras la crisis provocada por el COVID y la consiguiente necesidad de utilizar nuevas modalidades de atención. Se abordan seis aspectos inherentes a la TP: la satisfacción de los pacientes y del personal de salud mental, la fiabilidad diagnóstica, la eficacia de la intervención de la TP, la rentabilidad en términos de coste-oportunidad (o eficiencia) y los aspectos legales inherentes a la confidencialidad y la privacidad en particular y la actitud de los profesionales hacia la TP. La satisfacción con el TP es aceptable tanto entre los pacientes como entre los profesionales, siendo estos últimos los más reacios. La fiabilidad diagnóstica está demostrada, pero requiere de más estudios que confirmen esta fiabilidad en diferentes diagnósticos y entornos sanitarios. La eficacia de los tratamientos con TP no es inferior a la atención presencial, como se ha comprobado en psicoterapias específicas. Por último, hay que destacar que la actitud del psiquiatra es el elemento más decisivo que limita o facilita la implantación del TP. This review paper analyzes the state of knowledge on Telepsychiatry (TP) after the crisis caused by COVID and the resulting need to use new modalities of care. Six essential aspects of TP are addressed: patient’s and mental health staff satisfaction, diagnostic reliability, effectiveness of TP interventions, cost-effectiveness in terms of opportunity cost (or efficiency), legal aspects inherent to confidentiality and privacy in particular and the attitude of professionals towards TP. Satisfaction with TP is acceptable among both patients and professionals, the latter being the most reluctant. Diagnostic reliability has been demonstrated, but requires further studies to confirm this reliability in different diagnoses and healthcare settings. The efficacy of TP treatments is not inferior to face-to-face care, as has been proven in specific psychotherapies. Finally, it should be noted that the attitude of the psychiatrist is the most decisive element that limits or facilitates the implementation of TP.

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