Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 1.952
Filter
Add filters

Year range
1.
British Journal of Sports Medicine ; 2022.
Article in English | ProQuest Central | ID: covidwho-2161828

ABSTRACT

ObjectiveTo describe the incidence and burden of illness at the Tokyo 2020 Paralympic Games, which was organised with strict COVID-19 countermeasures.MethodsDaily illnesses were recorded via the web-based injury and illness surveillance system (teams with their own medical staff;n=81), and local polyclinic services (teams without their own medical staff;n=81). Illness proportion, incidence and burden were reported for all illnesses and in subgroups by sex, age, competition period, sports and physiological system.Results4403 athletes (1853 female and 2550 male) from 162 countries were monitored for the 15-day period of the Tokyo Paralympic Games (66 045 athlete days). The overall incidence of illnesses per 1000 athlete days was 4.2 (95% CI 3.8 to 4.8;280 illnesses). The highest incidences were in wheelchair tennis (7.1), shooting (6.1) and the new sport of badminton (5.9). A higher incidence was observed in female compared with male athletes (5.1 vs 3.6;p=0.005), as well as during the precompetition versus competition period (7.0 vs 3.5;p<0.0001). Dermatological and respiratory illnesses had the highest incidence (1.1 and 0.8, respectively). Illness burden was 4.9 days per 1000 athlete days and 23% of illnesses resulted in time loss from training/competition>1 day.ConclusionThe incidence of illness at the Tokyo 2020 Paralympic Games was the lowest yet to be recorded in either the summer or winter Paralympic Games. Dermatological and respiratory illnesses were the most common, with the burden of respiratory illness being the highest, largely due to time loss associated with COVID-19 cases. Infection countermeasures appeared successful in reducing respiratory and overall illness, suggesting implementation in future Paralympic Games may mitigate illness risk.

2.
Journal of Electrical and Electronics Engineering ; 15(2):76-81, 2022.
Article in English | ProQuest Central | ID: covidwho-2157218

ABSTRACT

- Covid-19 is an infectious disease that attacks the respiratory system caused by the coronavirus found in 2019. It has a deadly infection and rapid spread worldwide without exception in Indonesia. Then since the year, World Health Organization (WHO) has declared it a world pandemic. One way to prevent the spread of Covid-19, especially in the closed public area, is by spraying disinfectant to kill the virus. In this project, a low-end disinfectant sprayer has been built based on an Arduino system. The sprayer has been applied to a 10.3mx7.8m classroom with 30 units of the misting device. Performance test of the system shows that the sprayer can work accurately at the timetable to spray the classroom by consuming 58.31 W in operation and 19.80W in standby mode. The total hardware implementation cost is IDR 904,225 or less than USD 65, making affordability for implementing the system.

3.
Medical Journal of Malaysia ; 77(Supplement 4):46, 2022.
Article in English | EMBASE | ID: covidwho-2147523

ABSTRACT

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) a virus from the Coronaviridae family that causes the Coronavirus disease (COVID-19), has emerged and spread since December 2019. Since then, many in vitro and in vivo models for COVID-19 research has been developed. Objective(s): This study aimed to determine infectivity rate of various SARS-CoV-2 strains in the Vero E6 cell line. Material(s) and Method(s): Four SARS-CoV-2 strains (Wuhan, Alpha, Beta, and Delta) were isolated from clinical samples. Virus titre concentration of all strains were measured using Tissue Culture Infectious Dose (TCID50) assay and Plaque assay. At similar virus titre concentration, all strains were incubated in the Vero E6 cells at 37degreeC for 72 hours. At the end of incubation period, all virus cultures were terminated and analysed using TCID50 assay. Result(s) and Conclusion(s): It was found that the Wuhan strain has the highest infectivity rate (3601 PFU/mL/72hours) towards the Vero E6 cells, followed by Alpha (2946 PFU/mL/72hours), Beta (1780 PFU/mL/72hours) and Delta (571 PFU/mL/72hours). Vero E6 cell is commonly used for virus isolation and propagation, however this cell does not mimic the primary entry sites in the human respiratory track. The successful isolation and culture of SARS-CoV-2 in the Vero E6 cell is multifactorial, with high viral titre in source clinical samples and low passage number of cell culture as key factors. Vero E6 cell is susceptible towards all SARS-CoV-2 strains and can be used as in vitro COVID-19 culture model. Further studies can be conducted to determine the influence of different cell lines on the COVID-19 infectivity.

4.
Journal of Risk Research ; 25(9):1047-1145, 2022.
Article in English | GIM | ID: covidwho-2124350

ABSTRACT

This special issue contains 7 articles that discuss COVID-19 and vaccination refusal, theories on intention to be vaccinated, culture, health attitudes and behaviour, vaccine rollout management and communication, and risk perception and policy compliance.

5.
Respir Res ; 23(1): 320, 2022 Nov 19.
Article in English | MEDLINE | ID: covidwho-2139301

ABSTRACT

BACKGROUND: COVID-19 related acute respiratory distress syndrome (ARDS) has specific characteristics compared to ARDS in other populations. Proning is recommended by analogy with other forms of ARDS, but few data are available regarding its physiological effects in this population. This study aimed to assess the effects of proning on oxygenation parameters (PaO2/FiO2 and alveolo-arterial gradient (Aa-gradient)), blood gas analysis, ventilatory ratio (VR), respiratory system compliance (CRS) and estimated dead space fraction (VD/VT HB). We also looked for variables associated with treatment failure. METHODS: Retrospective monocentric study of intubated COVID-19 ARDS patients managed with an early intubation, low to moderate positive end-expiratory pressure and early proning strategy hospitalized from March 6 to April 30 2020. Blood gas analysis, PaO2/FiO2, Aa-gradient, VR, CRS and VD/VT HB were compared before and at the end of each proning session with paired t-tests or Wilcoxon tests (p < 0.05 considered as significant). Proportions were assessed using Fischer exact test or Chi square test. RESULTS: Forty-two patients were included for a total of 191 proning sessions, median duration of 16 (5-36) hours. Considering all sessions, PaO2/FiO2 increased (180 [148-210] vs 107 [90-129] mmHg, p < 0.001) and Aa-gradient decreased (127 [92-176] vs 275 [211-334] mmHg, p < 0.001) with proning. CRS (36.2 [30.0-41.8] vs 32.2 [27.5-40.9] ml/cmH2O, p = 0.003), VR (2.4 [2.0-2.9] vs 2.3 [1.9-2.8], p = 0.028) and VD/VT HB (0.72 [0.67-0.76] vs 0.71 [0.65-0.76], p = 0.022) slightly increased. Considering the first proning session, PaO2/FiO2 increased (186 [165-215] vs 104 [94-126] mmHg, p < 0.001) and Aa-gradient decreased (121 [89-160] vs 276 [238-321] mmHg, p < 0.001), while CRS, VR and VD/VT HB were unchanged. Similar variations were observed during the subsequent proning sessions. Among the patients who experienced treatment failure (defined as ICU death or need for extracorporeal membrane oxygenation), fewer expressed a positive response in terms of oxygenation (defined as increase of more than 20% in PaO2/FiO2) to the first proning (67 vs 97%, p = 0.020). CONCLUSION: Proning in COVID-19 ARDS intubated patients led to an increase in PaO2/FiO2 and a decrease in Aa-gradient if we consider all the sessions together, the first one or the 4 subsequent sessions independently. When considering all sessions, CRS increased and VR and VD/VT HB only slightly increased.


Subject(s)
COVID-19 , Respiratory Distress Syndrome , Humans , Adult , Retrospective Studies , Prone Position , Respiration, Artificial , COVID-19/therapy , Respiratory Distress Syndrome/diagnosis , Respiratory Distress Syndrome/therapy
6.
J Laryngol Otol ; 136(7): 588-603, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-2133061

ABSTRACT

BACKGROUND: This meta-analysis provides a quantitative measure of the otorhinolaryngological manifestations of coronavirus disease 2019 in children. METHODS: A structured literature review was carried out using PubMed, Embase and Cochrane Central, employing pertinent search terms. The statistical analysis was performed using Stata version 14.2 software, and the analysed data were expressed as the pooled prevalence of the symptoms with 95 per cent confidence intervals. RESULTS: The commonest symptoms noted were cough (38 per cent (95 per cent confidence interval = 33-42; I2 = 97.5 per cent)), sore throat (12 per cent (95 per cent confidence interval =10-14; I2 = 93.7 per cent)), and nasal discharge (15 per cent (95 per cent confidence interval = 12-19; I2 = 96.9 per cent)). Anosmia and taste disturbances showed a pooled prevalence of 8 per cent each. Hearing loss, vertigo and hoarseness were rarely reported. CONCLUSION: Cough, sore throat and nasal discharge were the commonest otorhinolaryngological symptoms in paediatric patients with coronavirus disease 2019. Compared with adults, anosmia and taste disturbances were infrequently reported in children.


Subject(s)
COVID-19 , Pharyngitis , Adult , Anosmia , COVID-19/complications , COVID-19/epidemiology , Child , Cough/epidemiology , Cough/etiology , Humans , Pharyngitis/epidemiology
7.
Mol Cell Biochem ; 2022 Nov 21.
Article in English | MEDLINE | ID: covidwho-2128944

ABSTRACT

Coronavirus disease-2019 (COVID-19) is associated with cytokine storm and is characterized by acute respiratory distress syndrome (ARDS) and pneumonia problems. The respiratory system is a place of inappropriate activation of the immune system in people with multiple sclerosis (MS), and this may cause damage to the lung and worsen both MS and infections.The concerns for patients with multiple sclerosis are because of an enhance risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The MS patients pose challenges in this pandemic situation, because of the regulatory defect of autoreactivity of the immune system and neurological and respiratory tract symptoms. In this review, we first indicate respiratory issues associated with both diseases. Then, the main mechanisms inducing lung damages and also impairing the respiratory muscles in individuals with both diseases is discussed. At the end, the leading role of physical exercise on mitigating respiratory issues inducing mechanisms is meticulously evaluated.

8.
Journal of Family Medicine and Primary Care ; 11(9):5014-5023, 2022.
Article in English | GIM | ID: covidwho-2144215

ABSTRACT

Since the pandemic of the coronavirus disease 2019 (COVID-19) infection, many people have been affected in different ways. The majority of infected people experience mild to moderate symptoms and recover without the need for hospitalization. However, in some affected people, it may lead to catastrophic disease. The severity of COVID-19 infection is widely influenced by co-morbidities, immune system functions, and extra-pulmonary organ injuries. Since the emergence of COVID-19, multi-organ involvement has been documented. In order to implement preventative and protective measures, full attention to potential organ injuries is required. Most existing articles and review papers are focused on a specific organ system, and their numbers are growing. In this review paper, attempts were made to collect review papers and articles published on seven organ system involvements in COVID-19 infection published till 15 July and highlight conclusions and managements of all affected organs. We tried to add to the medical knowledge on COVID-19, pointing out its multi-organ system impact. Finally, we tried to facilitate access to organized information and optimum conclusion by representing review tables for each organ system. Besides, this review article can clarify and magnify the empty research space easily for future investigations.

9.
2022 Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology, USBEREIT 2022 ; : 74-77, 2022.
Article in English | Scopus | ID: covidwho-2136506

ABSTRACT

The world is witnessing a rapid increase in the need for new techniques and methods that allow monitoring of the respiratory system, especially after the emergence of the Covid-19 pandemic. To determine the respiratory rate, respiratory pattern, and inhaled and exhaled cycles, transthoracic bio-impedance signals were used. That showed great effectiveness in monitoring, but to obtain this signal in most cases method requires a large number of electrodes, which must be placed in uncomfortable places for the patient in the case of long-term monitoring. In this work, the possibility of monitoring the respiratory rate and pattern has been studied using signals recorded from different thoracic areas by four bio- impedance channels, which are placed in comfortable places for long-term monitoring. The right thoracic channel showed stability in signal and the best correlation with the respiratory pattern extracted from the transthoracic channel and the study results recommend using it for long-term monitoring. © 2022 IEEE.

10.
8th IEEE International Conference on Smart Instrumentation, Measurement and Applications, ICSIMA 2022 ; : 181-184, 2022.
Article in English | Scopus | ID: covidwho-2136327

ABSTRACT

This work is motivated by the challenges faced during the COVID-19 pandemic. Effective protection from the virus is needed. Masks is one way to protect from the virus. To support the efforots to control the spread of COVID-19 among the population, in this work we present an improved respiratory system consisting of a respiratory mask, air blower and a control system. Our design avoids some of the problems with available masks such as leak of unfiltered air and the irritation caused by these masks. To overcome this problem, the existing respirator is being modified to ensure user can breathe comfortably, no air gap on the side of respirator mask and respirator mask can measure air suction rate. Air blower will increase the air suction rate and sensor will detect the air quality and display it thru the monitor. User can monitor the air index surround them. A prototype is built. Testing of the prototype showed that the system functions as expected and achieves its objectives. On the downside, the prototype is heavier than existing products in the market. Further improvement in the design may lead to an improved version with reduced weight. © 2022 IEEE.

11.
2022 International Conference on Innovative Computing, Intelligent Communication and Smart Electrical Systems, ICSES 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2136318

ABSTRACT

Viral diseases like Covid-19 are infectious and attack human respiratory system. During this time, places such as the hospital, supermarket and stations where crowds gather are at high risk of contamination. People in the vicinity of these areas can spread the virus not only through physical contact but also by touching articles or objects which are prone to contamination. This is why a device that can clean those infected areas without spreading it to others is much needed. To help mitigate this infectious disease the project was created to build a disinfectant robot that can be used remotely without heavy maintenance and has only one major installation cost and no continuous costs. That is the reason behind selecting the method of UV lamps to help sanitize public areas that can be extended to any type of public space at low cost and to decontaminate the area without the use of sprayers or reagents. All of these virus cleansers come in the form of aerosolized sprays or solutions but cannot be used everywhere particularly to clean garment factories or industrial surfaces. So, the UV lamps were finally selected that will be installed on a movable base automatically. © 2022 IEEE.

12.
IOP Conference Series Earth and Environmental Science ; 1104(1):012027, 2022.
Article in English | ProQuest Central | ID: covidwho-2134675

ABSTRACT

Covid-19, a disease characterized by Severe Acute Respiratory Syndrome, is caused by Coronavirus-2 (SARS-CoV-2). This virus causes tissue damage and a decrease in the respiratory system. Agarwood (Aquilaria spp) is a plant that has various pharmacological activities, including relieving respiratory diseases. One of the several secondary metabolites reported in Aquilaria spp. is oleanane triterpenoids, suspected of having antiviral activity. This research was aimed to determine the potential of oleanane triterpenoids from Agarwood as a covid-19 antiviral by in silico study. The research methods were molecular docking, prediction of Lipinski rules of five, and prediction of ADME. As a receptor, main protease (Mpro) Covid-19 was used. The four oleanane triterpenoid compounds in Agarwood demonstrated a higher affinity for the main protease covid-19 (ΔG 11-oxo-β-amyrin = -9.8 kcal/mol, ΔG hederagenin-an = -9.6 kcal/mol, ΔG 3β-acetoxyfriedelane = -9.4 kcal/mol, ΔG ursolic acid = -9.5 kcal/mol) than Lopinavir (ΔG = -6.2 kcal/mol) and Remdesivir (ΔG = -7.2 kcal/mol). The major amino acids involved in ligand and receptor interactions are methionine 49 and 165, proline 168, glutamine 189, arginine 188, and threonine 25. According to the prediction of Lipinski's rule of five and ADME, hederageninan is potential for development as oral medicine.

13.
5th International Conference on Applications of Fluid Dynamics, ICAFD 2020 ; : 241-249, 2023.
Article in English | Scopus | ID: covidwho-2128497

ABSTRACT

COVID-19 is symptomized with a great downfall in the proper functioning of the respiratory system of an affected human. The present work revolves around the research made to study the number of people infected with time under several circumstances. These circumstances include the lockdown introduced by the ruling governments. Additionally, we have shown a pattern for the infected people when the disease can be transmitted through airborne mode. In the present work, we intend to consider a transmission rate that is imparted, to the existing rate, by the airborne nature of the coronavirus. This adds novelty to our present work. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

14.
Farmaceutski Glasnik ; 78(7-8):349-360, 2022.
Article in Croatian | EMBASE | ID: covidwho-2125302

ABSTRACT

Chronic obstructive pulmonary disease (COPD) is a common lung disease that is characterized by long-term respiratory symptoms and airflow limitation. It is important to investigate whether patients with COPD are at the increased risk of infection with SARS-CoV-2 and what are the clinical outcomes of Coronavirus disease 2019 (COVID-19). Since both diseases affect the respiratory tract, the purpose of this review was to determine whether there is an interrelationship between COPD and COVID-19. Currently, it is not clear whether COPD patients are at higher risk of SARS-CoV-2 infection;however, it is confirmed that, if they are affected by COVID-19, there is a higher rate of hospitalisation and death. COPD patients should continue prescribed COPD therapy even if they have COVID-19 infection because it is not confirmed that taking these medications changes the clinical outcomes of COVID-19 infection. Protective measures are very important in times of higher prevalence of COVID-19 since they reduce the risk of infection and help COPD patients maintain their health. Copyright © 2022 Hrvatsko Farmaceutsko Drustvo. All rights reserved.

15.
Meditsinski Pregled / Medical Review ; 58(6):57-61, 2022.
Article in Bulgarian | GIM | ID: covidwho-2112067

ABSTRACT

Over two and a half years have passed since the WHO declared the SARS-CoV-2 pandemic. Thanks to the accumulated vast experience, especially in countries with a well-developed healthcare, systematized and reliable diagnostic approaches have been made available. Using such molecular biological methods, a current infection with SARS-CoV-2 can be diagnosed: either via sequencing viral nucleic acids or by using chromatographic tests demonstrating viral proteins (rapid antigen tests). Individuals presenting with symptoms consistent with COVID-19, should be tested for a SARS-CoV-2 infection and the sample should be taken from the upper respiratory tract (nasopharynx, nasal and/or oropharynx). It is generally accepted that RT-PCR is the most sensitive and specific diagnostic test. This method allows for qualitative detection of SARS-CoV-2 nucleic acid, by specifically targeting ORF1ab, N and Edomain in the viral genome. The "rapid antigen tests" detect the virus as early as 3-7 days after infection. The sensitivity of the rapid antigen tests does not change compared to the variants of the virus discovered thus far, including the new subtypes of the "Omicron" variant. The principal of this test is based on the detection of the N-protein (nuclear protein). Since the N-protein has remained relatively stable with respect to structural changes, the sensitivity of rapid antigen tests remains high.

16.
Journal of Tropical Medicine ; 21(12):1612-1616, 2021.
Article in Chinese | GIM | ID: covidwho-2112056

ABSTRACT

Corona virus disease 2019 (COVID-19) is an emerging pandemic of highly contagious caused by severe acute respiratory syndrome coronavirus -2 (SARS-CoV-2). Understanding the infectivity of various clinical samples and its transmission routes have been the main focus of current researches since the causative pathogens was identified. In this comprehensive review, we discuss the viral shedding from different clinical samples and reveal that infectious virus may be mainly discharged through respiratory and digestive systems. Also, SARS-CoV-2 showed a potential tropism for eyes, kidney, testis, placenta and other extrapulmonary tissues and high viral loads correlated with severe conditions. A better understanding of viral shedding may help the studies on pathogenesis and transmission of SARS-CoV-2 and provide suggestions for the disease control.

17.
Ieee Access ; 10:106180-106190, 2022.
Article in English | Web of Science | ID: covidwho-2082950

ABSTRACT

Contacts between people are the main drivers of contagious respiratory infections. For this reason, limiting and tracking contacts is a key strategy for controlling the COVID-19 epidemic. Digital contact tracing has been proposed as an automated solution to scale up traditional contact tracing. However, the required penetration of contact tracing apps within a population to achieve a desired target in controlling the epidemic is currently under discussion within the research community. In order to understand the effects of digital contact tracing, several mathematical models have been studied. In this article, we propose a novel compartmental SEIR model with which it is possible, differently from the models in the related literature, to derive closed-form conditions regarding the control of the epidemic. These conditions are a function of the penetration of contact tracing applications and testing efficiency. Closed-form conditions are crucial for the understandability of models, and thus for decision makers (including digital contact tracing designers) to correctly assess the dependencies within the epidemic. Feeding COVID-19 data to our model, we find that digital contact tracing alone can rarely tame the epidemic: for unrestrained COVID-19, this would require a testing turnaround of around 1 day and app uptake above 80% of the population, which are very difficult to achieve in practice. However, digital contact tracing can still be effective if complemented with other mitigation strategies, such as social distancing and mask-wearing.

18.
Ieee Access ; 10:105149-105168, 2022.
Article in English | Web of Science | ID: covidwho-2082607

ABSTRACT

As long as the COVID-19 pandemic is still active in most countries worldwide, rapid diagnostic continues to be crucial to mitigate the impact of seasonal infection waves. Commercialized rapid antigen self-tests proved they cannot handle the most demanding periods, lacking availability and leading to cost rises. Thus, developing a non-invasive, costless, and more decentralized technology capable of giving people feedback about the COVID-19 infection probability would fill these gaps. This paper explores a sound-based analysis of vocal and respiratory audio data to achieve that objective. This work presents a modular data-centric Machine Learning pipeline for COVID-19 identification from voice and respiratory audio samples. Signals are processed to extract and classify relevant segments that contain informative events, such as coughing or breathing. Temporal, amplitude, spectral, cepstral, and phonetic features are extracted from audio along with available metadata for COVID-19 identification. Audio augmentation and data balancing techniques are used to mitigate class disproportionality. The open-access Coswara and COVID-19 Sounds datasets were used to test the performance of the proposed architecture. Obtained sensitivity scores ranged from 60.00% to 80.00% in Coswara and from 51.43% to 77.14% in COVID-19 Sounds. Although previous works report higher accuracy on COVID-19 detection, this research focused on a data-centric approach by validating the quality of the samples, segmenting the speech events, and exploring interpretable features with physiological meaning. As the pandemic evolves, its lessons must endure, and pipelines such as the proposed one will help prepare new stages where quick and easy disease identification is essential.

19.
2nd International Conference on Computing and Machine Intelligence, ICMI 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2063260

ABSTRACT

COVID-19 is contagious virus that first emerged in China in 2019's last month. It mainly infects the both the lungs and the respiratory system. The virus has severely impacted life and the economy, which exposed threats to governments worldwide to manage it. Early diagnosis of COVID-19 could help with treatment planning and disease prevention strategies. In this study, we use CT-Scanned images of the lungs to show how COVID-19 may be identified using transfer learning model and investigate which model achieved the best and fastest results. Our primary focus was to detect structural anomalies to distinguish among COVID-19 positive, negative, and normal cases with deep learning methods. Every model received training with and without transfer learning and results were compared for various versions of DenseNet and EfficientNet. Optimal results were obtained using DenseNet201 (99.75%). When transfer learning was applied, all models produced almost similar results. © 2022 IEEE.

20.
Chest ; 162(4):A751, 2022.
Article in English | EMBASE | ID: covidwho-2060682

ABSTRACT

SESSION TITLE: Cardiovascular Complications in Patients with COVID-19 SESSION TYPE: Rapid Fire Case Reports PRESENTED ON: 10/19/2022 12:45 pm - 1:45 pm INTRODUCTION: Previous case reports have shown a number of cardiac complications associated with, and attributed to COVID-19 infection including acute myocardial injury and infarction, dysrhythmias, acute heart failure, pericarditis, and venous thromboembolic events, among others. Up until this point, these cases have all been documented in unvaccinated individuals 1. CASE PRESENTATION: Here we report a unique case of a 40-year-old previously vaccinated woman who presented with generalized weakness, chest pain, dyspnea, and vomiting. She was found to be septic and positive for COVID-19. Transthoracic echocardiogram showed a small pericardial effusion on admission and the patient was diagnosed with acute myopericarditis secondary to COVID-19. Within the first 24 hours following admission, the patient's condition rapidly deteriorated and she developed worsening pericardial effusion, with subsequent cardiac tamponade, and cardiogenic shock. Following attempted pericardiocentesis and surgical drainage, cardiac function did not improve and she expired soon after. DISCUSSION: Despite most of the clinical attention being focused on the effects of SARS-CoV-2 on the respiratory system and the pneumonia it causes, there have been more reported complications involving other organ systems, particularly the heart and kidneys. Studies have shown three main categories of cardiac involvement and complications related to COVID-19: myocardial injury, acute heart failure, and arrhythmia. Focusing on myocardial injuries, there have been some reports attempting to elucidate the frequency of myo- and pericarditis as complications of COVID-19. Yet still to this date, little is known about pericarditis as a COVID-19 complication. Of the case reports published thus far regarding COVID-19 pericarditis, the majority of them do not exhibit cardiac tamponade. In one systematic review published in September, 2021, a total of 33 studies including 32 case reports and one case series were included and pericardial effusion and cardiac tamponade were reported in 76% and 35% of the cases, respectively 2. To our knowledge, our case is the first of its kind, illustrating cardiac tamponade in a fully vaccinated individual. Although, there have been no clear mechanisms explaining the pathogenesis of cardiac involvement in patients suffering from COVID-19, multiple possibilities have been hypothesized. Similar to other cardiotoxic viruses, an inflammatory response is likely triggered resulting in pericarditis and pericardial effusion 3. When left unabated, cardiac tamponade can occur. CONCLUSIONS: Our case documents a reminder of the critical nature of SARS-CoV-2, even in vaccinated patients. To our knowledge, this is the first reported case of cardiac tamponade in a previously vaccinated individual. This case highlights the importance of quick diagnosis and treatment in patients suffering from potential lethal complications of COVID-19. Reference #1: Long B, Brady WJ, Koyfman A, Gottlieb M. Cardiovascular complications in COVID-19. Am J Emerg Med. 2020;38(7):1504-1507 Reference #2: Diaz-Arocutipa C, Saucedo-Chinchay J, Imazio M. Pericarditis in patients with COVID-19: a systematic review. J Cardiovasc Med (Hagerstown). 2021 Sep 1;22(9):693-700 Reference #3: Inciardi RM, Lupi L, Zaccone G, et al. Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020;5(7):819–24 DISCLOSURES: no disclosure on file for Thomas Bumbalo;no disclosure on file for Thaddeus Golden;No relevant relationships by Omar Kandah

SELECTION OF CITATIONS
SEARCH DETAIL