Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 2.159
Filter
1.
Mental Health & Prevention ; : 200243, 2022.
Article in English | ScienceDirect | ID: covidwho-1966947

ABSTRACT

Objevtives : Mental health among the older adults has been shown to be affected by reduced social interaction with friends. However, this relationship has not been confirmed in short periods of limited social interaction, such as that experienced during the COVID-19 pandemic. In this study, we investigated the relationship between the development of depressive symptoms and a 6-month decrease in the frequency of visits with friends among community-dwelling elderly in Japan. Methods : Participants were 491 community-dwelling older adults aged 65 years or older (47.5% female, mean age [standard deviation] = 80.5 [4.7] years) who responded to the March 2020 baseline survey by mail questionnaire and the October 2020 follow-up survey. Results : The onset of depressive symptoms was observed in 22.8% in about 6 months. The change in frequency of seeing friends, 56.2% remained unchanged, 23.2% increased, and 20.6% decreased. A logistic regression analysis with maintenance of frequency of seeing friends as a reference showed that a decreased frequency of seeing friends was significantly associated with the incidence of depressive symptoms. (odds ratio = 2.26, 95% confidence interval = 1.32-3.86, p = 0.003). Discussion : A decrease in the frequency of seeing friends over even a short period of time can have a negative impact on older adults’ mental health. The findings suggest that in situations where the frequency of seeing friends decreases during a short period of time, maintaining interaction with friends and avoiding face-to-face restrictions is important for maintaining the mental health of older adults.

2.
Psychoneuroendocrinology ; 144: 105888, 2022 Aug 02.
Article in English | MEDLINE | ID: covidwho-1967021

ABSTRACT

The COVID-19 pandemic led to increased distress in many children, particularly in girls. Socio-emotional vulnerability, as well as psychiatric symptomatology prior to or during the initial stages of the pandemic, have been identified as important predictors of this distress. Still, it is unclear whether the pandemic also had physiological repercussions in children. If so, it remains to be determined whether these same predictors could provide insight into inter-individual variability. This longitudinal study aimed to investigate the effects of socio-emotional vulnerability, as well as pre-pandemic internalizing and externalizing symptoms, on hair cortisol concentrations (HCC) in response to the COVID-19 pandemic in healthy youth. In June 2020 (T1), 69 healthy children (M = 11.57 y/o) who visited the laboratory between 2017 and 2019 (T0) provided a 6 cm hair sample. This technique allowed us to quantify cortisol secretion during the three months preceding the COVID-19 pandemic (Segment A) and during the first three months of the first wave of the pandemic in Quebec, Canada (Segment B). At T0, participants completed the Dominic Interactive to assess pre-pandemic internalizing and externalizing symptoms. A socio-emotional composite score (SECS) was derived using a weighted z-score with the following constructs: anxiety sensitivity (Childhood Anxiety Sensitivity Index) measured at T0, trait anxiety (Trait subscale of the State-Trait Anxiety Inventory for Children (STAI-C)), intolerance of uncertainty (Intolerance of Uncertainty Scale for Children), and trait rumination (Children's Response Style Scale) measured at T1. A linear regression was conducted using the percent change in HCC across Segment A and B as the dependent variable, where SECS, pre-pandemic internalizing and externalizing symptoms, and sex were used as predictors. We found a main effect of sex, with girls presenting increased HCC reactivity compared to boys. We also found that SECS and internalizing symptoms negatively predicted HCC, whereas the opposite relationship was found between externalizing symptoms and HCC reactivity. For healthy children, our results suggest that previous psychiatric symptoms and socio-emotional vulnerability may be risk factors for the presentation of diverging cortisol response patterns in response to an adverse life event (such as the COVID-19 pandemic).

3.
Pers Individ Dif ; 198: 111827, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-1966984

ABSTRACT

Experiencing stressors related to the COVID-19 pandemic such as health-related concern, social isolation, occupational disruption, financial insecurity, and resource scarcity can adversely impact mental health; however, the extent of the impact varies greatly between individuals. In this study, we examined the role of neuroticism as an individual-level risk factor that exacerbates the association between pandemic stressors and depressive symptoms. With repeated assessments of pandemic stressors and depressive symptoms collected from 3181 participants over the course of the pandemic, we used multilevel modeling to test if neuroticism moderated the association between pandemic stressors and depressive symptoms at both between- and within-person levels. At the between-person level, we found that participants who reported more pandemic stressors on average had higher levels of depressive symptoms and that this association was stronger among those high in neuroticism. At the within-person level, reporting more pandemic stressors relative to one's average on any given occasion was also associated with heightened depressive symptoms and this effect was similarly exacerbated by neuroticism. The findings point to pandemic stressor exposure and neuroticism as risk factors for depressive symptoms and, in demonstrating their synergistic impact, may help identify individuals at greatest risk for adverse psychological responses to the COVID-19 pandemic.

4.
Comput Human Behav ; 137: 107409, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-1966427

ABSTRACT

This study examined the link between the psychosocial well-being and social media use of international students in the US at the onset of the COVID-19 pandemic, when social isolation was mandated. Unlike prior research, which has typically focused on a single aspect of psychosocial well-being, we conceptualized international students' well-being as a multidimensional construct including internalizing symptoms (i.e., depression, anxiety, loneliness) as well as markers of intercultural difficulties. We then investigated social media use as a function of international students' idiosyncratic well-being vulnerabilities. A latent profile analysis revealed four groups with distinctive psychosocial profiles: well-adjusted students, interculturally adjusted students with internalizing symptoms, students with low internalizing symptoms but high intercultural difficulties, and maladjusted students with high internalizing symptoms and high intercultural difficulties. Supporting the social compensation perspective, maladjusted international students reported the highest engagement with social media compared to the other groups. These findings shed light on the unique and heterogenous experiences of international students at the onset of the pandemic. They also add nuance to the social compensation hypothesis by delineating person-specific associations between psychosocial well-being and social media use.

5.
Curr Psychol ; : 1-16, 2022 Jul 26.
Article in English | MEDLINE | ID: covidwho-1966185

ABSTRACT

The present study investigates the mediating roles of psychological inflexibility and differential coping strategies on perceived stress and post-traumatic symptoms and growth in the context of COVID-19. Study one recruited 662 participants (54.8% women; Mage = 40.64 years, SD = 13.04) who completed a cross-sectional questionnaire. It was proposed that orientation to the problem, avoidance strategies, psychological inflexibility, and positive attitude were mediators for the positive association between perceived stress and PTSD symptoms. The fit indices for the path model were excellent: CFI = 0.977, TLI = 0.950, RMSEA = 0.057 [90%CI = 0.043-0.081], and SRMS = 0.042. Gender and stressful events encountered had indirect effects on the endogenous variables. In study two, 128 participants (57.8% women; Mage = 42.30, SD = 12.08) were assessed for post-traumatic growth one year later. Psychological inflexibility and orientation acted as mediators between perceived stress and PTSD symptoms. Furthermore, a novel path model was constructed in which psychological inflexibility and orientation to the problem as mediators for perceived stress and PTSD symptoms. The indices for the path model were excellent: CFI = 0.99, TLI = 0.97, RMSEA = 0.055 [90%CI = 0.001-0.144], and SRMS = 0.49. Furthermore, PTSD symptoms, psychological inflexibility, and orientation to the problem predicted post-traumatic growth. Specifically, both orientation to the problem (ß = .06 [90%CI: .01;.13]) and psychological inflexibility (ß = .14 [90%CI: .08;.26]) had an indirect effect on post-traumatic growth. Overall, these results significantly contribute to the literature as orientation to the problem positively predicted PTSD symptoms and post-traumatic growth one year later while psychological inflexibility predicted PTSD symptoms and less post-traumatic growth one year later. These results underline the importance of assessing both symptomology and psychological growth to determine adaptive coping strategies in specific contexts.

6.
International Journal of Advanced Biological and Biomedical Research ; 10(1):18-31, 2022.
Article in English | GIM | ID: covidwho-1964939

ABSTRACT

Background: Coronavirus disease 2019 (COVID-19) is a pandemic caused by a novel coronavirus. On 30 January 2020, the first case of the COVID-19 was reported in India and it affects the whole world. The impact of various nutrients on the human immune system. To defend itself, the human body has numerous components. The human immune system identifies molecules that are foreign to its structure and responds to them in a useful manner. When a pathogen factor enters the human body, the immune system responds by triggering an immunological response.

7.
Zdravniski Vestnik ; 91(5/6):237-241, 2022.
Article in English | CAB Abstracts | ID: covidwho-1964493

ABSTRACT

COVID-19 is an unpredictable disease that can lead to multiorgan dysfunctions. There is a high frequency of venous and arterial thrombosis, among other symptoms. Spontaneous bleeding in COVID-19 patients has also been described, but rarely, whether or not they are on anticoagulant therapy. We report a case of a 65-year-old female COVID-19 patient treated in our hospital. During the hospitalisation, she experienced sudden, severe pain in the lower part of the abdomen and had signs of hemorrhagic shock. CT of the abdomen and pelvis revealed a spontaneous giant haematoma of the anterior abdominal wall. A surgical procedure was done. We identified spontaneous bleeding in the muscles of the anterior abdominal wall. The patient recovered well. Rapid diagnosis and timely intervention are crucial to ensure a good patient outcome.

8.
Indian Journal of Occupational and Environmental Medicine ; 26(1):34-38, 2022.
Article in English | CAB Abstracts | ID: covidwho-1964237

ABSTRACT

This conference proceeding contains 39 articles that discuss various topics related to occupational health. Discussed are hypersensitivity among farmers, prescription eye wear among toy makers, COVID-19 and comorbidity, personal protective equipment among health care workers, arrhythmia and COVID-19 among industrial worker and migrant workers, volatile organic compound exposure in a testing laboratory, catastrophic health expenditure among construction workers, musculoskeletal disorder symptoms among optometrists, stress among commercial airline pilots, health care practitioners, and lab technicians, bio-aerosols and flour mill workers, among others.

9.
Proceedings of the Latvian Academy of Sciences ; 76(3):338-345, 2022.
Article in English | ProQuest Central | ID: covidwho-1963315

ABSTRACT

This retrospective single-centre study was conducted in an intensive care unit (ICU) in Pauls Stradiņš Clinical University Hospital (Rīga, Latvia) between 1 October 2020 and 30 April 2021. The aim was to assess the baseline clinical characteristics and their association with outcome for critically ill coronavirus disease 2019 (COVID-19) patients admitted to the ICU and requiring invasive mechanical ventilation (IMV). Demographic, clinical, laboratory, length-of-stay and mortality data were collected from medical records. In total, 66 critically ill patients admitted to the ICU were enrolled in this study. 77% were male, and the median age was 65.5 [57.0–70.8] years. Comorbidi-ties included obesity (67.2%), cardiovascular disease (63.6%) and type II diabetes (38.1%). Prone positioning was performed in most cases (68.2%) and one-third (34.8%) of patients required renal replacement therapy during their stay in the ICU. The median time to intubation after hospitalisation was eight [3.3–10.0] days. The median length-of-stay in the ICU was 12 [6.0–18.5] days and the overall mortality among all invasively ventilated patients in the ICU was 86%. In survivors, the duration of time between the onset of symptoms and hospitalisation, and time between the onset of symptoms and intubation, were found to be shorter than in non-survivors.

10.
Genetika ; 54(1):427-438, 2022.
Article in English | GIM | ID: covidwho-1963294

ABSTRACT

Early, rapid and reliable identification of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is crucial for successful control of coronavirus disease 2019 (COVID-19). The quantitative real-time reverse transcription polymerase chain reaction (RT-PCR) assay is considered the gold standard for molecular diagnosis of SARS-CoV-2. The objective of this study was to compare the clinical performances of the three authorized tests - the Abbott Real Time SARS-CoV-2 (ACOV) assay (Abbott Molecular Inc., North Chicago, IL), GeneFinderTM COVID-19 Plus RealAmp (GeneFinder) Kit (OSANG Healthcare Co., Ltd, Dongan-gu Anyang, Korea) and the Biomerieux ARGENER SARS-COV-2 R-GENER real-time detection (ARGENE) kit (bioMerieux SA., Marcyl'Etoile, France) and to determine whether the selection of targeted genes has an impact on test's specificity. In this study, we included 155 nasopharyngeal swabs (NPS) from adult individuals with symptoms or suspected of COVID-19, aged from 17 to 91 years, previously tested by the ACOV and subsequently tested by the GeneFinder and the ARGENE. In this comparative analysis, we found that the GeneFinder assay detected the most cases of COVID-19 infection, followed by the ACOV assay, and then by ARGENE. Positive agreement ranged from 74.74% to 95.41%, with the strongest agreement observed between the GeneFinder and ACOV assays - 95.41% (95% confidence intervals (CI): 89.37%-98.36%) indicating an excellent agreement between these two tests and the lowest agreement between the GeneFinder and ARGENE assay - 74.74% (95% CI: 65.08%-81.41%). The negative percent agreement was 100% (GeneFinder/ACOV, GeneFinder/ARGENE and ACOV/ARGENE). Only 3.2% of cases were false-negative using the ACOV test, while 18.0% of samples were false-negative using the ARGENE assay to detect SARS-CoV-2. Combined usage of the Abbott SARS-CoV-2 and the GeneFinder assays can be applied to maximize SARS-CoV-2 detection accuracy.

11.
Current Respiratory Medicine Reviews ; 18(2):152-157, 2022.
Article in English | Scopus | ID: covidwho-1963208

ABSTRACT

Background: The present study aimed to assess the prevalence of persistent/late complications after recovery from the acute phase of COVID-19 in emergency medical technicians (EMTs). Methods: This is a cross-sectional case-series study performed during the last quarter of 2020 in Tehran, Iran. All EMTs who had been diagnosed with COVID-19 were eligible. The researcher contacted the EMTs via telephone to determine any complications following their recovery. Those who suffered from any complication were referred to an internal specialist physician for a detailed history and physical examination. Based on the physician’s opinion, some paraclinical or clinical evaluations were requested to be performed. Results: Four hundred thirty-one confirmed cases and two deaths due to this disease were registered among the Tehran EMS center’s EMTs during the study period. Two hundred thirty-eight EMTs were contacted, and 22.7% of them had at least one persistent/late complication following recovery of the acute phase of COVID-19;of whom, 28 EMTs were visited by an internist and completed the tests. The final participants mentioned seventy-five persistent/late complications. Only one EMT had a residual lesion among those who underwent lung CT scans. There were also some pathological findings in the echocardiographic examination and spirometry. Conclusion: Our study showed that persistent/late-onset complications could likely accompany by COVID-19. © 2022 Bentham Science Publishers.

12.
Front Pediatr ; 10: 909849, 2022.
Article in English | MEDLINE | ID: covidwho-1963504

ABSTRACT

Background: In the pediatric population, the knowledge of the acute presentation of SARS-CoV-2 infection is mainly limited to small series and case reports, particularly when dealing with neurological symptoms. We describe a large cohort of children with acute SARS-CoV-2 infection, focusing on the neurological manifestations and investigating correlations between disease severity and population demographics. Methods: Patients aged 0-18 years with a positive molecular swab were recruited between April 2020 and March 2021 from a tertiary Italian pediatric centre. Clinical data, imaging, and laboratory test results were retrieved from our local dataset and statistically analyzed. Results: A total of 237 patients with a median age of 3.2 years were eligible; thirty-two (13.5%) presented with neurological symptoms, including headache (65.6%), altered awareness (18.8%), ageusia/anosmia (12.5%), seizures (6.3%), and vertigo (6.3%), combined in 7 (21.9%) cases. Respiratory (59.5%) and gastrointestinal (25.3%) symptoms were the most common among the 205 (86.5%) patients without neurological involvement. Neurological symptoms did not significantly influence the severity of the triage access codes. Moreover, pre-existing medical conditions were not higher in the group with neurological manifestations. Overall, fifty-nine patients (25%, 14/59 with neurological symptoms) required treatment, being antibiotics, systemic steroids, and heparin those most prescribed. Conclusion: Our study supports the overall benign course of the SARS-CoV-2 infection in children. Neurological manifestations, except for headache, remain a rare presenting symptom, and disease severity seems unrelated to pre-existing medical conditions.

13.
Neurology Perspectives ; 1:S16-S24, 2021.
Article in English, Spanish | Scopus | ID: covidwho-1959890

ABSTRACT

Introduction: SARS-CoV-2 infection frequently causes neurological symptoms. Cognitive alterations are among the most frequent symptoms, and may persist beyond the acute phase of infection. Methods: We conducted a narrative review of the literature. Results: Hospitalised patients, and especially critically ill patients, are at greater risk of developing cognitive symptoms. Post–COVID-19 cognitive symptoms, unlike those associated with other viral illnesses, have been observed in patients with mild infection, and present some atypical features. Cognitive symptoms may last longer in COVID-19 than in other infectious processes, and more frequently affect young people. Post–COVID-19 cognitive symptoms share common features with those described in chronic fatigue syndrome, including a similar profile with affective symptoms. Brief screening tests for cognitive impairment present suboptimal diagnostic performance, and standardised criteria are needed to ensure correct diagnosis. Post–COVID-19 cognitive impairment can have a significant impact on the patient's quality of life and functional independence, regardless of other post–COVID-19 symptoms. Currently, no specific treatments have been approved for post–COVID-19 cognitive impairment, although cognitive stimulation may be useful in some patients. Conclusions: Post–COVID-19 cognitive symptoms are common and are often associated with other systemic symptoms. Neuropsychological evaluation may be useful for diagnosis and to quantify their severity and long-term prognosis. Detailed, and individualised assessment of cognitive impairment may enable the design of treatment plans. © 2021 Sociedad Española de Neurología

14.
Neurology Perspectives ; 1:S5-S15, 2021.
Article in English, Spanish | Scopus | ID: covidwho-1959887

ABSTRACT

Introduction: Post-COVID-19 syndrome is a series of chronic signs and symptoms that may appear after SARS-CoV-2 infection, including fatigue, dyspnoea, chest pain, palpitations, anxiety, depression, and joint and muscle pain. The purpose of this study was to review the controversies on post-COVID-19 syndrome, the frequency of neurological symptoms, and the potential pathophysiological mechanisms. Methods: We present a narrative review of studies published in PubMed since the beginning of the pandemic (January 2020–July 2021). Results: Patients with history of COVID-19 have been found to present persistent neurological symptoms, including cognitive complaints, memory and concentration problems, headache, anosmia, ageusia, vertigo, and insomnia. Post-COVID-19 syndrome is a heterogeneous disease that lacks a universally accepted definition, which may explain the great variability in the estimated prevalence (2.3%–85%) and symptom duration. The criteria differentiating post-COVID-19 syndrome from chronic fatigue syndrome or critical illness syndrome are ambiguous. Risk factors include older age, female sex, certain comorbidities, and greater number of symptoms in the acute phase. The pathophysiology of the syndrome is largely unknown, although it is probably multifactorial, including immunological mechanisms, neural network dysfunction, neurotransmitter alterations, persistent viral damage, and functional impairment. Conclusions: Post-COVID-19 syndrome may present after mild or even asymptomatic SARS-CoV-2 infection, causing limitations in activities of daily living and in quality of life. Further research will clarify the origin and most appropriate management of these neurological alterations. © 2021 Sociedad Española de Neurología

15.
BJPsych Bull ; : 1-5, 2022 Jul 04.
Article in English | MEDLINE | ID: covidwho-1962918

ABSTRACT

The topic of this article is the biopsychosocial model. My main contention is that - notwithstanding doubts as to what exactly it is, or indeed whether it is anything - there is a coherent account of it, in terms of both applications to particular health conditions and mechanisms with wide application. There is accumulating evidence from recent decades that psychosocial as well as biological factors are implicated in the aetiology and treatment of a large range of physical as well as mental health conditions. The original proposer of the biopsychosocial model, George Engel, back in 1977, was substantially correct about what he saw was on its way.

16.
BMC Pregnancy Childbirth ; 22(1): 104, 2022 Feb 05.
Article in English | MEDLINE | ID: covidwho-1962772

ABSTRACT

OBJECTIVES: Infection control measures during the Covid-19 pandemic have focused on limiting physical contact and decontamination by observing cleaning and hygiene rituals. Breastfeeding requires close physical contact and observance of hygienic measures like handwashing. Worries around contamination increase during the perinatal period and can be expressed as increase in obsessive compulsive symptoms. These symptoms have shown to impact breastfeeding rates. This study attempts to explore any relationship between the Covid-19 pandemic and perinatal obsessive-compulsive symptomatology and whether the Covid-19 pandemic has any impact on intent to breastfeed. METHODS: A cross sectional survey of perinatal women attending largest maternity centre in Qatar was carried out during the months of October to December 2020. Socio-demographic information, intent to breastfeed and information around obsessive compulsive thoughts around Covid-19 pandemic were collected using validated tools. RESULTS: 15.7% respondents report intent to not breastfeed. 21.4% respondents reported obsessive-compulsive symptoms. 77.3% respondents believed the biggest source of infection was from others while as only 12% of the respondents believed that the source of infection was through breastfeeding and 15.7% believed the vertical transmission as the main source of risk of transmission. CONCLUSIONS: The rates of Obsessive-compulsive symptoms were increased and the rates of intent to breastfeed were decreased when compared with pre pandemic rates. The obsessive-compulsive symptoms and the intent to not breastfeed were significantly associated with fear of infection to the new-born. Obsessive-compulsive symptoms were not significantly correlated with intent to breastfeed and can be seen as adaptive strategies utilized by women to continue breastfeeding in the context of fear of infection.


Subject(s)
Breast Feeding/psychology , COVID-19/psychology , Intention , Obsessive-Compulsive Disorder/psychology , Adult , COVID-19/transmission , Cross-Sectional Studies , Female , Humans , Hygiene , Infectious Disease Transmission, Vertical/prevention & control , Perinatal Care , Pregnancy , Qatar/epidemiology , SARS-CoV-2
17.
Open Forum Infect Dis ; 9(7): ofac275, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1961127

ABSTRACT

Background: Patient-reported outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are an important measure of the full burden of coronavirus disease (COVID). Here, we examine how (1) infecting genotype and COVID-19 vaccination correlate with inFLUenza Patient-Reported Outcome (FLU-PRO) Plus score, including by symptom domains, and (2) FLU-PRO Plus scores predict return to usual activities and health. Methods: The epidemiology, immunology, and clinical characteristics of pandemic infectious diseases (EPICC) study was implemented to describe the short- and long-term consequences of SARS-CoV-2 infection in a longitudinal, observational cohort. Multivariable linear regression models were run with FLU-PRO Plus scores as the outcome variable, and multivariable Cox proportional hazards models evaluated effects of FLU-PRO Plus scores on return to usual health or activities. Results: Among the 764 participants included in this analysis, 63% were 18-44 years old, 40% were female, and 51% were White. Being fully vaccinated was associated with lower total scores (ß = -0.39; 95% CI, -0.57 to -0.21). The Delta variant was associated with higher total scores (ß = 0.25; 95% CI, 0.05 to 0.45). Participants with higher FLU-PRO Plus scores were less likely to report returning to usual health and activities (health: hazard ratio [HR], 0.46; 95% CI, 0.37 to 0.57; activities: HR, 0.56; 95% CI, 0.47 to 0.67). Fully vaccinated participants were more likely to report returning to usual activities (HR, 1.24; 95% CI, 1.04 to 1.48). Conclusions: Full SARS-CoV-2 vaccination is associated with decreased severity of patient-reported symptoms across multiple domains, which in turn is likely to be associated with earlier return to usual activities. In addition, infection with the Delta variant was associated with higher FLU-PRO Plus scores than previous variants, even after controlling for vaccination status.

18.
Open Forum Infect Dis ; 9(7): ofac270, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1961126

ABSTRACT

Symptoms of long coronavirus disease (COVID) were found in 38% of 170 patients followed for a median of 22.6 months. The most prevalent symptoms were fatigue, affected taste and smell, and difficulties remembering and concentrating. Predictors for long COVID were older age and number of symptoms in the acute phase. Long COVID may take many months, maybe years, to resolve.

19.
Eur J Public Health ; 2022 Jul 22.
Article in English | MEDLINE | ID: covidwho-1961033

ABSTRACT

BACKGROUND: The study explored the relationship between physical activity (PA) behaviour and severity of symptoms in people infected by coronavirus-disease 2019 (COVID-19). METHODS: Five hundred thirty-three people (16% males, mean age: 45 ± 11 yrs., body mass index (BMI): 23.3 ± 20) took part in the study. All participants were post-COVID-19 infection. An online questionnaire was used to gather data on; participants demographics, comorbidities and treatment, symptomatology of COVID-19, quality of life (QoL) and pre- and post-COVID-19 infection PA. RESULTS: Logistic regression revealed that only a high BMI (> 25) increased the severity of (OR 1.01; 95% CI, 0.99-1.03) symptoms from none to mild-to-moderate. Weekly PA behaviour (mins/week) did not affect the primary outcome (symptom severity) as a predictor variable and neither differ (p > 0.05) between symptomatology for both moderate (no symptoms: 181.3 ± 202.1 vs. mild-to-moderate symptoms: 173 ± 210.3), and vigorous (no symptoms: 89.2 ± 147 vs. mild-to-moderate symptoms: 88.9 ± 148.3) PA. QoL (i.e., mobility, self-care, usual activities, pain/discomfort, anxiety/depression, and perceived health) was significantly (p < 0.05) worse post-COVID-19 infection. CONCLUSIONS: Our findings did not present an association between PA levels and mild-to-moderate COVID-19 symptoms. However, all participants exceeded the lower limit of the WHO-recommended, adult PA dose. This might explain the lack of PA effect, on mild-to-moderate symptoms post-COVID-19 infection. Future studies should explore the effects of PA levels in more severe cases (e.g., hospitalisations) and assess the effectiveness of PA to reduce hospitalisations, and mortality rates as a result of COVID-19 infection.

20.
Crit Rev Food Sci Nutr ; : 1-19, 2022 Jul 27.
Article in English | MEDLINE | ID: covidwho-1960715

ABSTRACT

The outbreak of the COVID-19 pandemic has brought great problems to mankind, including economic recession and poor health. COVID-19 patients are frequently reported with gastrointestinal symptoms such as diarrhea and vomiting in clinical diagnosis. Maintaining intestinal health is the key guarantee to maintain the normal function of multiple organs, otherwise it will be a disaster. Therefore, the purpose of this review was deeply understanded the potential mechanism of SARS-CoV-2 infection threatening intestinal health and put forward reasonable treatment strategies. Combined with the existing researches, we summarized the mechanism of SARS-CoV-2 infection threatening intestinal health, including intestinal microbiome disruption, intestinal barrier dysfunction, intestinal oxidative stress and intestinal cytokine storm. These adverse intestinal events may affect other organs through the circulatory system or aggravate the course of the disease. Typically, intestinal disadvantage may promote the progression of SARS-CoV-2 through the gut-lung axis and increase the disease degree of COVID-19 patients. In view of the lack of specific drugs to inhibit SARS-CoV-2 replication, the current review described new strategies of probiotics, prebiotics, postbiotics and nutrients to combat SARS-CoV-2 infection and maintain intestinal health. To provide new insights for the prevention and treatment of gastrointestinal symptoms and pneumonia in patients with COVID-19.

SELECTION OF CITATIONS
SEARCH DETAIL