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1.
Journal of Southwest Minzu University Natural Science Edition ; 48(2):135-141, 2022.
Article in Chinese | CAB Abstracts | ID: covidwho-1958497

ABSTRACT

Feline Astrovirus (FAstV), Feline Parvovirus(FPV) and Feline Enteric Coronavirus (FECoV) are important pathogens causing diarrhea in cats.In order to establish a molecular detection method which can differentiate the three pathogens in the same PCR system, an FAstV/FPV/FECoV triple PCR method was established with optimized primer concentrations and annealing temperature, and specificity, sensitivity and repeatability were tested. The results showed that the PCR method could only identify FAstV (320 bp), FPV (468 bp) and FECoV (664 bp) genes, while not other canine and feline related pathogens. The detection limits of FAstV, FPV and FECoV were 2x10~7 copy/L (7.1 pg/L),4.7x10~6 copy/L (2.4 pg/L) and 7x10~6 copy/L (5.1 pg/L) respectively. The established triple PCR method was used to detect 207 cat fecal samples collected in Chengdu from 2019 to 2020, including 141 diarrhea samples and 66 clinical health samples. The detection rates of FAstV, FPV and FECoV were 24.15% (50/207), 37.20% (77/207) and 15.46% (32/207) respectively, and the co-infection rates of FAstV/FPV, FPV/FECoV and FAstv/FECoV were 9.18%,6.28% and 6.28% respectively. In conclusion, the triple PCR method of FAstV/FPV/FECoV was successfully established, and could be applied for virus detection and epidemiological investigation.

2.
Issues in Science and Technology ; 38(4):39-44, 2022.
Article in English | ProQuest Central | ID: covidwho-1958458

ABSTRACT

Decades before the COVID-19 pandemic demonstrated how rapidly infectious diseases could emerge and spread, the world faced the AIDS epidemic. Initial efforts to halt the contagion were slow as researchers focused on understanding the epidemiology of the virus. It was only by integrating epidemiological theory with behavioral theory that successful interventions began to control the spread of HIV. As the current pandemic persists, it is clear that similar applications of interdisciplinary theory are needed to inform decisions, interventions, and policy. Continued infections and the emergence of new variants are the result of complex interactions among evolution, human behavior, and shifting policies across space and over time. Due to this complexity, predictions about the pandemic based on data and statistical models alone--in the absence of any broader conceptual framework--have proven inadequate. Classical epidemiological theory has helped, but alone it has also led to limited success in anticipating surges in COVID-19 infections. Integrating evolutionary theory with data and other theories has revealed more about how and under what conditions new variants arise, improving such predictions.

3.
Uttar Pradesh Journal of Zoology ; 43(8):20-23, 2022.
Article in English | GIM | ID: covidwho-1958427

ABSTRACT

Just as the smell gets diluted by ventilation, the dangerous concentration of the virus can also get reduced by ensuring appropriate amount of outdoor air flows in. In closed and stale space droplets and aerosol gets quickly concentrated and greatly increases the risk of transmission of virus in that area. Visit to any nearby shopping malls, newly furnished coaching classes, modern residential buildings, government offices, hotels, restaurants and even hospitals shows that they are nothing but an assortment of closed and unventilated spaces. These closed space acts as Super spreader of the virus. Peak test positive rate of 22.6% per hundred test is observed during the month of May, which is a result of high humidity particulate matter concentration temperature CO2 concentration.

4.
Perspectives in Public Health ; 142(2):58-126, 2022.
Article in English | CAB Abstracts | ID: covidwho-1958412

ABSTRACT

This article contains 12 articles that discuss the relevance and role of cultural activities and the arts, particularly music, in the health and wellness of people especially during the COVID-19 pandemic.

5.
Journal of Southwest Minzu University Natural Science Edition ; 48(2):181-189, 2022.
Article in Chinese | GIM | ID: covidwho-1958057

ABSTRACT

After the large-scale vaccination of the coronavirus disease 2019(COVID-19), the traditional manual registration cannot track each vaccine from production to vaccination, as well as the vaccinators. It is easy to cause the lack and omission of registration information, and is not conducive to analyze the data of large-scale vaccine and vaccination. Therefore, this paper uses the front-end and back-end separated patterns with front-end using Vue and Elment-UI technology, and back-end using SpringBoot and Mybatis-Plus framework. It designs and realizes the whole-process management system of novel coronavirus vaccine, from vaccine logistics and vaccine warehousing management, to vaccination and post-vaccination tracking, and then to the forum management of vaccinators. The system aims to achieve "whole-process, traceable" management goal of vaccines. The system is feasible and practical, which can alleviate the problem of manual recording and collation of medical staff in vaccine management, and provide a convenient and information-based vaccination platform for medical staff and vaccinators. In addition, the system can collect the data on the whole process of vaccines and provide strong data support for scientific research work.

6.
Current Science ; 122(3):244-246, 2022.
Article in English | GIM | ID: covidwho-1957973

ABSTRACT

This article highlights the diffusion of the COVID-19 pandemic across the globe at continental scales and within continents at national scales. Using raw metrics (cumulative deaths and population) and per capita metrics (cumulative deaths per million of population) collected from April 2020 to 31 December 2021, results showed that Europe, North America, and South America had reached a relatively high evenness of spread. However, in Asia and Africa, a much larger concentration exists in a few areas. It is possible that in these two continental regions, there is not only poor connectivity, which offers natural barriers to transmission, but also high levels of undercounting.

7.
American Journal of Public Health ; 112(8):1115-1119, 2022.
Article in English | ProQuest Central | ID: covidwho-1957939

ABSTRACT

Sadly, Celina's experience at the US border is not uncommon, although her ultimate admission to the United States is rare indeed. Because ofthe confluence of MPP and the 2020 invocation of 42 US Code 265 (hereafter "Title 42"), an obscure public health policy last updated in 1944, more than a million expulsions of migrants and asylum seekers occurred at the US border in fiscal year 2021 alone, contrary to international law.1 POLICY BACKGROUND The policy known today as Title 42 originated in a 1944 law called the Public Health Service Act, which (among other things) granted the federal government quarantine powers and the power to prevent the introduction of disease at the border. Robert Redfield, then director of the Centers for Disease Control and Prevention (CDC), determined that introduction into congregate settings of persons from Canada or Mexico would increase the already serious danger to the public health of the United States to the point of requiring a temporary suspension of the introduction of covered aliens into the United States.3 The same order also noted the logistical challenges of preventing the transmission ofCOVID-19 at the border: Widespread, compulsory federal quarantines or isolations of such persons pending test results are impracticable due to the numbers of persons involved, logistical challenges, and CDC resource and personnel constraints.3 Although the US government did not have access to vaccines or rapid tests in March 2020, they need not have adopted such an extreme policy to protect the public's health. Given the barriers to effective implementation of PPE [personal protective equipment] and administrative controls to prevent the spread of [COVID-19] in immigration detention centers, an evidence-based public health approach suggests . . . the release of detainees from immigration detention centers, as this strategy will reduce the likelihood of person-to-person infection and enhance the possibility of engaging in meaningful social distancing and hygienic practices as directed by the CDC.4(p112) That the US government invoked Title 42 for those coming through land borders but instituted only temporary travel bans for other international travelers and did not institute interstate travel bans underscores how unnecessary these extreme measures truly were, even in the early days of COVID-19.5 In addition to the challenges posed by the use of Title 42 to prevent the entry of asylum seekers during COVID-19, MPP-often referred to as the Remain in Mexico program- creates additional barriers for migrants seeking to enter the United States.

8.
Bulletin des GTV ; 104:85-92, 2021.
Article in French | CAB Abstracts | ID: covidwho-1957885

ABSTRACT

Coronaviruses have a high evolutionary capacity which has led to their very large genetic diversity. Their prevalence in nature is very high and they can infect a wide spectrum of hosts including mammals (including humans) and birds. To date, six porcine coronaviruses have been identified. Two of which were responsible for severe epizootics in pigs with a major impact in the global swine industry in the 60's to 80's for porcine transmissible gastroenteritis virus and since the 2010's in China and 2014 in North America for porcine epidemic diarrhoea virus. The latter has also become the third most important pathogen for pigs in China after the African swine fever virus and the porcine reproductive and respiratory syndrome virus. This review summarizes the latest developments in scientific knowledge of these porcine coronaviruses.

9.
Biomedica ; 42(Suppl. 2), 2022.
Article in Spanish | CAB Abstracts | ID: covidwho-1957852

ABSTRACT

Introduction: The severe acute respiratory syndrome of the new coronavirus (SARS-CoV-2) is the causal agent of the health emergency due to the COVID-19 pandemic. Although humans are the main susceptible host, experimental studies and reported cases of natural infection have evidenced scenarios of SARS-CoV-2 reverse zoonosis in animals.

10.
Journal of School of Public Health & Institute of Public Health Research ; 19(4):413-422, 2022.
Article in Persian | CAB Abstracts | ID: covidwho-1957775

ABSTRACT

Background and Aim: The objective of this study was to determine the seroepidemiological history of SARS-CoV-2 infection among asymptomatic children in Tehran. Materials and Methods: Blood samples of children younger than 14 years old were collected during the period autumn-winter 2020 and spring 2021 and tested for SARS-CoV-2 IgG antibody using the EUROIMMUN ELISA kit. In addition, questionnaires were used to collect demographic and infection status information in the participants. Data were analyzed using the SPSS software.

11.
Journal of Public Health Management and Practice ; 28(Suppl. 1):S1-S110, 2022.
Article in English | GIM | ID: covidwho-1957724

ABSTRACT

This special issue includes 15 articles focusing on how public health professionals at local, state, and federal agencies and at academic institutions can address the pervasive structural racism against Asians by making them visible. Topics discussed are: anti-Latino racism, the racial state, and revising approaches to racial disparities;conquering the health disparities of structural racism;embedding equity in a local government's Response to COVID-19;the Massachusetts racial equity data road map;the power of community in addressing infant mortality inequities;disparities across income and health insurance in a national sample of US adults;community-informed mobile COVID-19 testing model to addressing health inequities.

12.
Journal of Medical Virology ; 94(3):799-1247, 2022.
Article in English | GIM | ID: covidwho-1957723

ABSTRACT

This special issue contains 63 papers on the topic of COVID-19 and other respiratory diseases.

13.
Journal of Medical Virology ; 94(5):1757-2307, 2022.
Article in English | GIM | ID: covidwho-1957722

ABSTRACT

This special issue contains 74 articles (2 commentaries, 17 letters to the editor, 8 reviews, 40 research articles, 7 short communications) that discusses topics related to COVID-19 and its variants. Topics include new drugs against COVID-19, detection of variants, antibody response, evolution and phylogeny, monoclonal antibodies, symptoms, among others.

14.
Annals of Epidemiology ; 67:102-131, 2022.
Article in English | GIM | ID: covidwho-1957708

ABSTRACT

This conference proceeding contain 39 articles that discuss epidemiology in the US. Topics include the Millenium Cohort Study, The CRONICAS Cohort Study, religious beliefs, coping mechanisms and type 2 diabetes, spatio-temporal modelling of COVID-19, cigarette smoking and spinal pain, self-perceived health status and obesity, oral cancer and smoking, renal impairment and diabetes, depression and BMI, affordable housing and COVID-19, opioid misuse among youth, emotions and cancer prevention, influenza vaccination among adults, blood lead levels and private wells, and air pollution and amyotrophic lateral sclerosis.

15.
Medical Immunology ; 24(4):705-728, 2022.
Article in Russian | Academic Search Complete | ID: covidwho-1955153

ABSTRACT

Secretory phospholipases A2 (sPLA2) represent a large superfamily of enzymes with a molecular weight of 14-19 kDa, including 15 groups and more than 30 isoforms belonging to four types: secretory (sPLA2), cytosolic (cPLA2), calcium-independent (iPLA2) and lipoprotein-associated phospholipase A2 (LP-PLA2, PAF-AH). Eleven species of secretory sPLA2s (IB, IIA, IIC, IID, IIE, IIF, III, V, X, XIIA, and XIIB) have been found in mammals, performing versatile functions and participating in the pathogenesis of a wide range of diseases. On the one hand, sPLA2 may promote elimination of damaged, apoptotic cells by hydrolyzing membrane phospholipids, and exerts a strong bactericidal and antiviral properties, including pronounced effects against antibiotic-resistant strains of microorganisms. In this regard, the use of sPLA2 may represent a new strategy for the treatment of bacterial and viral infections. Moreover, due to the action of sPLA2 on its substrates, a number of biologically active molecules (arachidonic, lysophosphatidic acids, lysophospholipids, fatty acids, prostaglandins, leukotrienes, thromboxanes) are formed, which provide strong inflammatory, detergent, coagulating effects and increase vascular permeability. This pro-inflammatory role of sPLA2 may explain its increase levels and activity in cardiovascular, respiratory, autoimmune, metabolic, oncological, bacterial and viral disorders. The review article presents a classification of sPLA2 isoforms, their substrates, regulatory factors, biological significance, and mechanisms of their strong bactericidal, virucidal, and proinflammatory activity in the heart and lung disorders, autoimmune, metabolic, bacterial, and viral diseases. In particular, the mechanisms of the selective action of sPLA2 against Gram-positive and Gram-negative microorganisms are discussed. We consider diagnostic and prognostic significance, correlations between elevated levels and activity of sPLA2 and distinct clinical symptoms, severity and outcome in the patients with coronary heart disease (CAD), acute myocardial infarction (AMI), atherosclerosis, acute inflammatory lung injury (ALI), respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), rheumatoid arthritis, bronchial asthma, bacterial infections, septicemia and viral (COVID-19) infections. The opportunity of using sPLA2 as a biomarker of the severity and outcome of patients with chronic obstructive pulmonary disease, bacterial infections, sepsis and viral infections, including COVID-19, is also considered. (English) [ FROM AUTHOR] Секреторные фосфолипазы А2 (sPLA2) представляют собой большое суперсемейство ферментов с молекулярной массой 14-19 кДа, включающее 15 групп и более 30 изоформ, принадлежащих к четырем типам: секреторный (sPLA2), цитозольный (cPLA2), кальций-независимый (iPLA2) и липопротеин-ассоциированная фосфолипаза A2 (LP-PLA2, PAF-AH). У млекопитающих обнаружены одиннадцать секреторных sPLA2 (IB, IIA, IIC, IID, IIE, IIF, III, V, X, XIIA и XIIB), выполняющие разносторонние функции и участвующие в патогенезе широкого спектра заболеваний. С одной стороны, sPLA2, гидролизуя фосфолипиды мембран, способствуют элиминации поврежденных, апоптотических клеток и оказывают сильное бактерицидное, вируцидное действие, в том числе против антибиотикорезистентных штаммов микроорганизмов. Ð’ этом плане использование sPLA2 может представлять новую стратегию терапии бактериальных и вирусных инфекций. С другой стороны, в результате действия sPLA2 на ее субстраты образуются биологически активные молекулы (арахидоновая, лизофосфатидная кислоты, лизофосфолипиды, жирные кислоты, простагландины, лейкотриены, тромбоксаны), которые оказывают сильное воспалительное, детергирующее, коагулирующее действие и повышают проницаемость сосудов. Такая провоспалительная роль sPLA2 обуславливает повышение ее уровней и активности при сердечно-сосудистых, дыхательных, аутоиммунных, метаболических, онкологических, бактериальных и вирусных заболеваниях. Ð’ обзоре приводится классификация изоформ sPLA2, рассматриваются их субстраты, регулирующие факторы, биологическое значение и механизмы сильного бактерицидного, вируцидного действия, а также провоспалительной активности при сердечно-сосудистых, дыхательных, аутоиммунных, метаболических, бактериальных и вирусных заболеваниях. Отдельно излагаются механизмы селективного действия sPLA2 в отношении грамположительных и грамотрицательных микроорганизмов. Обсуждаются диагностическая, прогностическая значимость, корреляции повышенных уровней и активности sPLA2 с клиническими симптомами, тяжестью и исходом пациентов с ишемической болезнью сердца (CAD), острыминфарктом миокарда (AMI), атеросклерозом, острым воспалительным повреждением легких (ALI), респираторным дистресс-синдромом (ARDS), хронической обструктивной болезнью легких (COPD), ревматоидным Ð°Ñ€Ñ‚Ñ€Ð¸Ñ Ð¾Ð¼, бронхиальной астмой, бактериальными инфекциями, сепсисом и вирусными (COVID-19) инфекциями. Рассматривается возможность использования sPLA2 в качестве биомаркера тяжести и исхода пациентов с хронической обструктивной болезнью легких, бактериальными инфекциями, сепсисом и вирусными, в том числе COVID-19, инфекциями. (Russian) [ FROM AUTHOR] Copyright of Medical Immunology (1563-0625) is the property of National Electronic-Information Consortium and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

16.
Journal of Transport and Supply Chain Management ; 16, 2022.
Article in English | ProQuest Central | ID: covidwho-1954242

ABSTRACT

Background: After coronavirus disease 2019 (COVID-19) was declared a pandemic, movement restrictions were implemented across sub-Saharan Africa. There has been much speculation on what the long-term impacts on urban transport might be. Objectives: The aim of this paper is to identify the revealed and future travel impacts of the pandemic. Method: To pursue this aim, evidence was compiled from two sources: secondary big data;and a ( n = 15) two-wave Delphi panel survey of experts in the region. Results: It is predicted that longer-term impacts will take the form of: reduced travel by, and accessibility for, low-income households residing in peripheral locations because of decreased welfare;reduced transport service availability;operator reduction (particularly amongst unsubsidised formal operators);increased remote activity participation for a minority of better resourced households with white-collar workers;and disrupted trip distributions as the mix of city-centre land use changes in response to business attrition in economic recession rather than to disrupted bid rents. Conclusion: The major impact of the pandemic is likely to be on welfare, rather than on trip substitution. There is a need, therefore, to focus policy on the mitigation of these impacts and, more particularly, on ways of measuring changes in transport disadvantage and exclusion so that reliable data are available to inform mitigation strategies. The mitigation strategies considered should include investment in affordable ‘digital connectivity’ as a means of complementing accessibility from physical proximity and mobility. The pandemic also highlights the need to develop more robust transport planning practices to deal with uncertainty.

17.
Pteridines ; 33(1):11-20, 2022.
Article in English | ProQuest Central | ID: covidwho-1951638

ABSTRACT

Background The authors explore the therapeutic and prophylactic efficacies of Immunopterin (calcium pterin-6-carboxylate chelate) against coronavirus colds and as a therapy against COVID-19. Methods To determine Immunopterin’s therapeutic efficacy against colds and flus, a 5-year observational study was conducted with 34 subjects who took Immunopterin when feeling symptoms of a cold or flu. The mean sample cold recovery time was compared to the US population mean. A review of the Moheno (2014) 2-year observational study was conducted to evaluate the prophylactic efficacy of Immunopterin against colds. Early COVID-19 case studies, treated with Immunopterin, were collected to explore Immunopterin’s efficacy as a therapeutic and prophylactic against COVID19 disease. Results The mean cold recovery time for the therapeutic sample in the cold/flu observational study was 30 h compared to the US population mean of 168 h (N = 34;p < 0.001). Subjects taking prophylactic Immunopterin reported 0% incidences of colds and flus (N = 31). Immunopterin successfully treated four confirmed COVID-19 subjects. A fifth clinical nurse case study demonstrates COVID-19 prevention. Conclusions The therapeutic and prophylactic efficacies of Immunopterin against coronavirus colds, along with reported cross-reactivity between coronavirus colds and SARS-CoV-2 strongly suggest Immunopterin can act as a therapy and preventative against COVID- 19 infection associated disease.

18.
Journal of Sensors ; 2022, 2022.
Article in English | ProQuest Central | ID: covidwho-1950382

ABSTRACT

The lockdown and the strict regulation measures implemented by Chinese government due to the outbreak of the COVID-19 pandemic not only decelerated the spread of the virus but also brought a positive effect on the nationwide atmospheric quality. In this study, we extended our previous research on remotely sensed estimation of PM2.5 concentrations in Yangtze River Delta region (i.e., YRD) of China from 2019 to the strict regulation period of 2020 (i.e., 24 Jan, 2020-31 Aug, 2020). Unlike the method using aerosol optical depth (AOD) developed in previous studies, we validated the possibility of moderate resolution imaging spectroradiometer (MODIS) top-of-atmosphere (TOA) reflectance (i.e., MODIS TOA) at 21 bands in estimating the PM2.5 concentrations in YRD region. Two random forests (i.e., TOA-sig RF and TOA-all RF) incorporated with different MODIS TOA datasets were developed, and the results showed that the TOA-sig RF model performed better with R2 of 0.81 (RMSE=8.07 μg/m3) than TOA-all RF model with R2 of 0.79 (RMSE=9.13 μg/m3). The monthly averaged PM2.5 exhibited the highest value of 50.81 μg/m3 in YRD region in January 2020 and sharply decreased from February to August 2020. The annual mean PM2.5 concentrations derived by TOA-sig RF model were 47.74, 32.14, and 21.04 μg/m3 in winter, spring, and summer in YRD during the strict regulation period of 2020, respectively, showing much lower values than those in 2019. Our research demonstrated that the PM2.5 concentrations could be effectively estimated by using MODIS TOA reflectance at 21 bands and the random forest.

19.
Journal of Mathematics ; 2022, 2022.
Article in English | ProQuest Central | ID: covidwho-1950364

ABSTRACT

Coronavirus disease 2019 (COVID-19) is currently threatening the entire world, and a novel coronavirus is a virus from the corona family that has spread a new infection. The number of instances of this disease is increasing at an exponential, but there are now commercially accessible COVID-19 vaccines. The weak symptoms of COVID-19 disease, on the other hand, are treated with a variety of antiviral treatments. It is still choosing the optimal antiviral medicine to manage COVID-19s. It is a challenging and difficult alternative to reduce the risk of infection. In this study, an improved combined compromise solution (CoCoSo) method is proposed to identify the ranking of alternatives. The introduction of a logarithmic picture fuzzy set is a more effective technique for representing variance, represented by three memberships (positive, neutral, and negative membership) degrees. This work introduces a fresh logarithmic picture fuzzy score function, to deal with the problem of comparison. The CoCoSo method-based logarithmic picture fuzzy decision-making algorithm is given. To achieve so, a new divergence measure for the logarithmic picture fuzzy number is introduced. To demonstrate the viability and efficacy of the established approach in real-world applications, a case study of COVID-19 disease drug selection is discussed.

20.
Kybernetes ; 51(8):2481-2507, 2022.
Article in English | ProQuest Central | ID: covidwho-1948701

ABSTRACT

Purpose>The purpose of this paper is to develop a system dynamics approach based on Susceptible, Exposed, Infected, Recovered (SEIR) model to investigate the coronavirus pandemic and the impact of therapeutic and preventive interventions on epidemic disaster.Design/methodology/approach>To model the behavior of COVID-19 disease, a system dynamics model is developed in this paper based on SEIR model. In the proposed model, the impact of people's behavior, contact reduction, isolation of the sick people as well as public quarantine on the spread of diseases is analyzed. In this model, data collected by the Iran Ministry of Health have been used for modeling and verification of the results.Findings>The results show that besides the intervening policies, early application of them is also of utmost priority and makes a significant difference in the result of the system. Also, if the number of patients with extreme conditions passes available hospital intensive care capacity, the death rate increases dramatically. Intervening policies play an important role in reducing the rate of infection, death and consequently control of pandemic. Also, results show that if proposed policies do not work before the violation of the hospital capacity, the best policy is to increase the hospital’s capacity by adding appropriate equipment.Research limitations/implications>The authors also had some limitations in the study including the lack of access to precise data regarding the epidemic of coronavirus, as well as accurate statistics of death rate and cases in the onset of the virus due to the lack of diagnostic kits in Iran. These parameters are still part of the problem and can negatively influence the effectiveness of intervening policies introduced in this paper.Originality/value>The contribution of this paper includes the development of SEIR model by adding more policymaking details and considering the constraint of the hospital and public health capacity in the rate of coronavirus infection and death within a system dynamics modeling framework.

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