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J Gastrointestin Liver Dis ; 29(3): 470, 2020 09 09.
Article in English | MEDLINE | ID: covidwho-729795
Blood Purif ; 50(2): 257-260, 2021.
Article in English | MEDLINE | ID: covidwho-619189


Hemoperfusion (HP) was helpful to prevent the development and progression of acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), liver failure, and septic shock by removing cytokines and other inflammatory mediators and ultimately preventing progression toward multiple organ failure. A 54-year-old man diagnosed with COVID-19 was hospitalized in the intensive care unit. The patient's O2 saturation was 80% using an oxygen mask, which was gradually declining. After 4 sessions of HP/continuous renal replacement therapies (CRRT), O2 saturation reached to 95%, and the patient was transferred to the general ward. Performing HP/CRRT at the early stages of ARDS can obviate the need for intubating patients with COVID-19. Punctual and early use of HP and CRRT in the treatment of ARDS in patients with COVID-19 prevented the progression of ARDS and patient intubation, reduced respiratory distress and the patient's dependence on oxygen, prevented other complications such as AKI and septic shock in the patient, and reduced mortality and hospital length of stay.

COVID-19/therapy , Continuous Renal Replacement Therapy , Cytokine Release Syndrome/therapy , Cytokines/blood , Hemoperfusion , Intubation, Intratracheal , Respiratory Distress Syndrome/therapy , SARS-CoV-2 , Acute Kidney Injury/etiology , Acute Kidney Injury/prevention & control , Anti-Bacterial Agents/therapeutic use , Anticoagulants/therapeutic use , Antiviral Agents/therapeutic use , COVID-19/blood , COVID-19/complications , Critical Care/methods , Cytokine Release Syndrome/blood , Cytokine Release Syndrome/etiology , Diabetes Mellitus, Type 2/complications , Diabetes Mellitus, Type 2/drug therapy , Humans , Hypertension/complications , Hypertension/drug therapy , Inflammation/blood , Inflammation/etiology , Length of Stay/statistics & numerical data , Male , Middle Aged , Oxygen/blood , Respiratory Distress Syndrome/blood , Respiratory Distress Syndrome/etiology , Respiratory Distress Syndrome/prevention & control , Shock, Septic/etiology , Shock, Septic/prevention & control , COVID-19 Drug Treatment