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1.
J Neuroinflammation ; 19(1): 2, 2022 Jan 04.
Article in English | MEDLINE | ID: covidwho-1603365

ABSTRACT

BACKGROUND: Anxiety disorders are the most prevalent mental illnesses in the U.S. and are estimated to consume one-third of the country's mental health treatment cost. Although anxiolytic therapies are available, many patients still exhibit treatment resistance, relapse, or substantial side effects. Further, due to the COVID-19 pandemic and stay-at-home order, social isolation, fear of the pandemic, and unprecedented times, the incidence of anxiety has dramatically increased. Previously, we have demonstrated dihydromyricetin (DHM), the major bioactive flavonoid extracted from Ampelopsis grossedentata, exhibits anxiolytic properties in a mouse model of social isolation-induced anxiety. Because GABAergic transmission modulates the immune system in addition to the inhibitory signal transmission, we investigated the effects of short-term social isolation on the neuroimmune system. METHODS: Eight-week-old male C57BL/6 mice were housed under absolute social isolation for 4 weeks. The anxiety-like behaviors after DHM treatment were examined using elevated plus-maze and open field behavioral tests. Gephyrin protein expression, microglial profile changes, NF-κB pathway activation, cytokine level, and serum corticosterone were measured. RESULTS: Socially isolated mice showed increased anxiety levels, reduced exploratory behaviors, and reduced gephyrin levels. Also, a dynamic alteration in hippocampal microglia were detected illustrated as a decline in microglia number and overactivation as determined by significant morphological changes including decreases in lacunarity, perimeter, and cell size and increase in cell density. Moreover, social isolation induced an increase in serum corticosterone level and activation in NF-κB pathway. Notably, DHM treatment counteracted these changes. CONCLUSION: The results suggest that social isolation contributes to neuroinflammation, while DHM has the ability to improve neuroinflammation induced by anxiety.


Subject(s)
Flavonols/pharmacology , Inflammation Mediators/antagonists & inhibitors , Inflammation Mediators/metabolism , Microglia/drug effects , Microglia/metabolism , Social Isolation/psychology , Animals , Anxiety/metabolism , Anxiety/prevention & control , Anxiety/psychology , Flavonols/therapeutic use , Male , Maze Learning/drug effects , Maze Learning/physiology , Mice , Mice, Inbred C57BL
2.
Eur Rev Med Pharmacol Sci ; 25(24): 7964-7970, 2021 Dec.
Article in English | MEDLINE | ID: covidwho-1608921

ABSTRACT

OBJECTIVE: The aim of the study was to develop mental health nursing strategies for the inbound quarantined population based on the results of a survey study and frontline nursing experiences. SUBJECTS AND METHODS: A mixed research method was selected, we collected data by questionnaires from 128 quarantined people, and by semi-structured interviews from 5 registered nurses. Generalized anxiety disorder-7 (GAD-7), the patient health questionnaire-9 (PHQ-9), the Pittsburgh Sleep Quality Index (PSQI), Social Support Rating Scale (SSRS) were used in the quantitative research to identify the prevalence of psychological issues and risk factors. Semi-structured interviews were conducted in the qualitative study to conclude nursing experiences from RNs. RESULTS: The overall prevalence of anxiety, depression, and insomnia were 34%, 41%, and 18% respectively. Binary logistic regression analysis showed that social support, urban residence, and chronic disease were associated with mental health problems in certain aspects. Three themes were emerged from the analysis of RNs interviews: personality, chronic diseases, and social support. CONCLUSIONS: The prevalence of mental health issues in the inbound quarantined population was the same as the general population in the initial stage of COVID-19 outbreak, and significantly lower than people who lived in high-risk areas. Living in urban areas, with chronic diseases, and obtaining less social support are the risk factors. Finally, four nursing strategies were proposed by the research team for mental health well-being.


Subject(s)
COVID-19/prevention & control , Mental Health/statistics & numerical data , Nurses/organization & administration , Psychiatric Nursing/organization & administration , Quarantine/psychology , Adult , Anxiety/epidemiology , Anxiety/prevention & control , Anxiety/psychology , COVID-19/epidemiology , COVID-19/transmission , China/epidemiology , Cross-Sectional Studies , Depression/epidemiology , Depression/prevention & control , Depression/psychology , Humans , Male , Pandemics/prevention & control , Prevalence , Professional Role , Quarantine/standards , Risk Factors , Self Report/statistics & numerical data , Sleep Initiation and Maintenance Disorders/epidemiology , Sleep Initiation and Maintenance Disorders/prevention & control , Sleep Initiation and Maintenance Disorders/psychology , Social Support/psychology , Social Support/statistics & numerical data , Young Adult
3.
PLoS One ; 16(12): e0261745, 2021.
Article in English | MEDLINE | ID: covidwho-1598351

ABSTRACT

BACKGROUND: COVID-19 pandemic has had a global major healthcare, social and economic impact. In present study we aim to adapt the Fear of COVID-19 Scale to Hungarian. MATERIALS AND METHODS: Forward-backward translation method was used to translate the English version of the scale to Hungarian. Participants were a convenience sample of 2175 university students and employees. The study was conducted between January 18th and February 12th 2021. The test battery included Hungarian versions of Fear of COVID-19 scale, short Beck Depression Inventory (BDI-H) and State-Trait Anxiety Inventory (STAI). RESULTS: The scale showed one-factor structure, the loadings on the factor were significant and strong (from .47 to .84). Internal consistency was very good (α = .84). Construct validity for the Fear of COVID-19 Scale was supported by significant and positive correlations with STAI (r = 0.402; p < 0.001) and BDI-H (r = 0.270; p < 0.001). CONCLUSION: The Hungarian version of Fear of COVID-19 Scale is a reliable and valid tool in assessing fear of coronavirus.


Subject(s)
COVID-19/epidemiology , COVID-19/psychology , Fear/psychology , Pandemics , Psychiatric Status Rating Scales/standards , Psychometrics/methods , SARS-CoV-2 , Adult , Aged , Aged, 80 and over , Anxiety/epidemiology , Anxiety/psychology , COVID-19/virology , Faculty/psychology , Female , Humans , Hungary/epidemiology , Male , Middle Aged , Reproducibility of Results , Students/psychology , Surveys and Questionnaires , Young Adult
4.
J Cancer Res Ther ; 17(6): 1540-1546, 2021.
Article in English | MEDLINE | ID: covidwho-1597096

ABSTRACT

Purpose: Coronavirus disease (COVID-19) pandemic has affected the entire health-care system and has led to a sense of fear and anxiety in the minds of patients. Patient's perceptions in this scenario of the pandemic are unknown. Providing continued care for cancer patients during the lockdown has been challenging. Measures are needed to improve patient safety and satisfaction during these challenging times and hence the importance of measuring the degree of satisfaction for the quality of care provided. The aim of the study was to evaluate the factors related to patients' satisfaction and also understand their apprehensions, fears, and anxieties they face as they receive radiotherapy treatment amid COVID-19 pandemic. The study's objective was to explore other aspects such as logistic issues, patient-staff communication, and also perceptions of the patients toward the outbreak. Materials and Methods: This study was conducted from April to September 2020. A questionnaire was created for which the patients were asked to provide answers. Parameters assessed included general information such as mode of transport used, frame of mind during treatment, awareness about pandemic, satisfaction toward care provided by health-care staff, and also documenting the suggestions to improve the quality of care. Results: During this period, we interviewed 108 patients: 56 males (51.9%) and 52 females (48.1%). 90.7% of the participants were satisfied with the condition and safety measures employed in waiting area and billing section. Majority (88.9%) were found to be aware about COVID-19. 74.1% of the participants were very satisfied with the services provided to them in the department of radiation oncology. Conclusion: The survey was useful in measuring the patient satisfaction, in understanding their fears and anxieties, and also in determining their awareness about the pandemic. The survey was also useful to get the patients' opinion and ideas for improvement in the health-care services.


Subject(s)
Neoplasms/radiotherapy , Patient Satisfaction/statistics & numerical data , Professional-Patient Relations , Tertiary Care Centers/statistics & numerical data , Adult , Aged , Anxiety/psychology , COVID-19/epidemiology , Communication , Fear/psychology , Female , Humans , India/epidemiology , Male , Middle Aged , Patient Safety , Quality of Health Care , SARS-CoV-2 , Surveys and Questionnaires
5.
Biomed Res Int ; 2021: 9928276, 2021.
Article in English | MEDLINE | ID: covidwho-1582875

ABSTRACT

Introduction: Coronavirus disease 2019 (COVID-19) is a global public health crisis. However, whether it can cause respiratory dysfunction or physical and psychological disorders in patients remains unknown. Thus, this study was conducted to investigate the respiratory function, activities of daily living, quality of life, and mental status of patients with COVID-19. Participants and outcomes. Data was collected from the follow-up of eligible patients who attended the fever clinic of three hospitals in Jiangxi Province, from March to May 2020. The outcomes included respiratory muscle function, degree of dyspnea, aerobic capacity, activities of daily living, quality of life, and mental status. Results: A total of 139 patients (72 men and 67 women) were included in this study. The proportions of mild, moderate, severe, and critical cases of COVID-19 were 7.1% (10 cases), 68.3% (95 cases), 20.1% (28 cases), and 4.2% (6 cases), respectively. The rates of abnormal maximal inspiratory pressure were 10.0%, 25.2%, 25.0%, and 16.7%, respectively. There were 50%, 65.3%, 50%, and 66.7% of the patients with abnormal dyspnea in the four clinical classifications, respectively. Patients generally show a decline in quality of life, anxiety, and depression symptoms. Conclusions: Respiratory dysfunction, decreased quality of life, and psychological disorders were present in each clinical classification of COVID-19. Therefore, it is necessary to carry out respiratory rehabilitation and psychological intervention for COVID-19 patients.


Subject(s)
Activities of Daily Living , COVID-19 , Quality of Life , Respiratory Mechanics , SARS-CoV-2 , Adult , Aged , Anxiety/physiopathology , Anxiety/psychology , Anxiety/rehabilitation , COVID-19/physiopathology , COVID-19/psychology , COVID-19/rehabilitation , Depression/physiopathology , Depression/psychology , Depression/rehabilitation , Female , Follow-Up Studies , Humans , Male , Middle Aged , Prospective Studies
6.
BMC Pregnancy Childbirth ; 21(1): 846, 2021 Dec 28.
Article in English | MEDLINE | ID: covidwho-1582096

ABSTRACT

BACKGROUND: The pregnant population experienced unique COVID-19 physical and psychosocial stressors such as direct health concerns related to the virus and loss of access to resources since the COVID-19 emerged as a global pandemic in early 2020. Despite these COVID-19-related stress and concerns, the maternal experience of bonding with their unborn children has not been well studied. This work aimed to study the association between mental health history, current mental health symptoms, psychological factors, COVID-19-related worries, and self-reported maternal-fetal bonding of pregnant women. METHODS: This online, survey-based cross-sectional study focused on women pregnant during the pandemic and assessed 686 women using data collected from May 19, 2020 to October 3, 2020. Enrolled respondents completed assessments in which they self-reported maternal-fetal bonding, mental health symptomatology, psychological factors, and COVID-19-related worries regarding health, pregnancy, and resources. RESULTS: Depressive symptoms in pregnant women were associated with lower quality maternal-fetal bonding, while a higher level of anxiety was positively associated with bonding; however, past history of depression or generalized anxiety diagnosis did not appear to be as relevant as active symptomatology. Maternal resilience, but not distress tolerance, appeared to be a protective factor resulting in improved bonding. Higher levels of worry regarding impact of COVID-19 on health were significantly associated with improved bonding, while worries regarding the impact of COVID-19 on the pregnancy or resources were not significantly associated with bonding. The study also found associations between different sociodemographic variables and bonding, including a strong positive association between first time motherhood and bonding and a negative association between higher education and income and bonding. CONCLUSIONS: This study was the first to report potential protective and risk factors to the maternal-fetal bonding process in women pregnant during the COVID-19 pandemic. Unique COVID-19 concerns exist; however, anxiety and COVID-19 concerns do not appear to undermine maternal-fetal bonding while active depressive symptomatology may negatively influence bonding; interventions increasing maternal resilience may be particularly valuable.


Subject(s)
COVID-19/psychology , Maternal-Fetal Relations/psychology , Adult , Anxiety/psychology , Cross-Sectional Studies , Depression/psychology , Female , Humans , Mental Health , Middle Aged , Pregnancy , Protective Factors , Resilience, Psychological , Risk Factors , SARS-CoV-2 , Surveys and Questionnaires
8.
Nutrients ; 13(12)2021 Nov 23.
Article in English | MEDLINE | ID: covidwho-1538436

ABSTRACT

The SARS-CoV-2 (COVID-19) pandemic has been associated with both increased anxiety, deterioration in diet and weight gain. These associations may differ by sex. The present report examines differences by sex in diet quality in order to determine whether associations between diet and psychological stress during the initial phase of the COVID-19 pandemic differed by sex. This online study is available internationally in seven languages. The Mediterranean Diet Score was used to measure diet quality, while the General Anxiety Disorder 7-point scale (GAD-7) was used to measure anxiety. Findings were compared by self-reported sex (male vs. female). A total of 3797 respondents provided informed consent and met eligibility criteria, of whom 526 women were omitted due to being pregnant or six months or less post-partum, or due to reproductive status not being reported. Thus, 3271 individuals are included in the present report, of whom 71.2% were women. The median age of women was 30 (interquartile range (IQR) = 16) years vs. 31 (IQR = 19) years, p = 0.079. The median diet quality score was 9 (IQ = 3) in both women and men (p = 0.75). Despite the overall similarity in diet score, several components of the score differed significantly by sex. Women reported consuming significantly more olive oil, daily servings of vegetables, and weekly servings of sweet baked goods. Men reported consuming significantly more sweetened/carbonated drinks, red meat, alcohol, legumes, and hummus/tahini. Women reported a GAD-7 score of 6 (IQR = 8), while men reported 3 (6), p < 0.001. An inverse association was detected between the Mediterranean diet score and the GAD-7 score in both women (rho = -0.166, p < 0.001) and men (rho = -0.154, p < 0.001), and the correlation coefficients did not differ by sex (p = 0.76). Mediterranean diet score and age both reduced the odds of elevated anxiety (GAD-7 ≥ 10), while female sex, deterioration of diet quality during the outbreak, unemployment, and completing the survey in English increased the odds of this outcome. During the COVID-19 lockdowns, overall diet quality did not differ by sex; however, some differences by sex in components of the total score were detected. Moderate to severe anxiety was positively associated with female sex and poorer diet quality even after controlling for age, employment status, and the language in which the survey was performed.


Subject(s)
Anxiety , COVID-19 , Food Preferences/psychology , Pandemics , SARS-CoV-2 , Sex Characteristics , Stress, Psychological , Adolescent , Adult , Anxiety/epidemiology , Anxiety/psychology , COVID-19/epidemiology , COVID-19/psychology , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Stress, Psychological/epidemiology , Stress, Psychological/psychology
9.
BMC Pregnancy Childbirth ; 21(1): 768, 2021 Nov 12.
Article in English | MEDLINE | ID: covidwho-1528682

ABSTRACT

BACKGROUND: Pregnant and postpartum women face unique challenges and concerns during the COVID-19 pandemic. Thus far, no studies have explored the factors associated with increased levels of worry in this population globally. The current study sought to assess the frequency and sources of worry during the COVID-19 pandemic in an international sample of pregnant and postpartum women. METHODS: We conducted an anonymous, online, cross-sectional survey in 64 countries between May and June 2020. The survey was available in 12 languages and hosted on the Pregistry platform for COVID-19 studies. Participants were sought mainly on social media platforms and online parenting forums. The survey included questions related to demographics, level of worry, support, stress, COVID-19 exposure, frequency of media usage, and mental health indicators. RESULTS: The study included 7561 participants. Eighty-three percent of all participants indicated that they were either 'somewhat' or 'very' worried. Women 13-28 weeks pregnant were significantly more likely to indicate that they were 'very worried' compared to those who were postpartum or at other stages of pregnancy. When compared with women living in Europe, those in Africa, Asia and Pacific, North America and South/Latin America were more likely to have increased levels of worry, as were those who more frequently interacted with social media. Different forms of support and stress also had an impact upon level of worry, while indicators of stress and anxiety were positively associated with worry level. CONCLUSION: Pregnant and postpartum women are vulnerable to the changes in societal norms brought about by the COVID-19 pandemic. Understanding the factors associated with levels of worry within this population will enable society to address potential unmet needs and improve the current and future mental health of parents and children.


Subject(s)
Anxiety/etiology , COVID-19/psychology , Pregnancy Complications/etiology , Adolescent , Adult , Anxiety/epidemiology , Anxiety/psychology , Cross-Sectional Studies , Female , Global Health/statistics & numerical data , Health Surveys , Humans , Logistic Models , Odds Ratio , Postpartum Period/psychology , Pregnancy , Pregnancy Complications/epidemiology , Pregnancy Complications/psychology , Risk Factors , Stress, Psychological/epidemiology , Stress, Psychological/etiology , Stress, Psychological/psychology , Young Adult
10.
Sci Rep ; 11(1): 22480, 2021 11 18.
Article in English | MEDLINE | ID: covidwho-1526099

ABSTRACT

Monitoring community psychological and behavioural responses to coronavirus disease 2019 (COVID-19) is important for informing policy making and risk communication to sustain public compliance with challenging precautionary behaviours and mitigating the psychological impacts. Monthly telephone-based cross-sectional surveys in January-April 2020 and then weekly surveys from May through December 2020 were conducted to monitor changes in public risk perception of COVID-19, personal efficacy in self-protection, confidence in government's ability to control the pandemic, precautionary behaviours, perceived impact of precautionary behaviours, psychological fatigue and distress in Hong Kong, and examine their inter-relationships. While worry about contracting COVID-19 increased, personal efficacy and confidence in government declined as the community incidence of COVID-19 increased. The public maintained high compliance with most precautionary behaviours throughout but relaxed behaviours that were more challenging when disease incidence declined. Public confidence in government was persistently low throughout, of which, a lower level was associated with more psychological fatigue, lower compliance with precautionary behaviours and greater psychological distress. Perceived greater negative impact of precautionary behaviours was also associated with more psychological fatigue which in turn was associated with relaxation of precautionary behaviours. Female, younger and unemployed individuals reported greater psychological distress throughout different stages of the pandemic. Risk communication should focus on promoting confidence in self-protection and pandemic control to avoid helplessness to act when the pandemic resurges. Policy making should prioritize building public trust, enhancing support for sustaining precautionary behaviours, and helping vulnerable groups to adapt to the stress during the pandemic.


Subject(s)
Anxiety , COVID-19 , Health Behavior , Pandemics , Psychological Distress , SARS-CoV-2 , Adolescent , Adult , Age Factors , Aged , Anxiety/epidemiology , Anxiety/psychology , COVID-19/epidemiology , COVID-19/psychology , Cross-Sectional Studies , Female , Hong Kong/epidemiology , Humans , Male , Middle Aged , Sex Factors
11.
Cephalalgia ; 41(14): 1437-1446, 2021 12.
Article in English | MEDLINE | ID: covidwho-1526573

ABSTRACT

BACKGROUND: Psychosocial variables are key factors influencing psycho-physical equilibrium in migraine patients. Social isolation and vulnerability to stressors may prevent efficient psychological adjustment negatively affecting adaptation to life changes, as that imposed during Covid-19 lockdown. Here, we explored psychosocial dimensions and changes in clinical condition during Covid-19 lockdown in migraine patients, with regard to migraine type and headache impact. METHODS: Sixty-four migraine patients (32 episodic and 32 chronic) and 64 healthy control subjects were included in a case-control cross-sectional study. A two-step clustering procedure split patients into two clusters, based on the Headache Impact Test. Perceived global distress, loneliness, empathy, and coping levels were compared in groups, as well as changes in clinical condition. RESULTS: Migraine patients reported higher general loneliness and lower social support compared to healthy control subjects. Emotional loneliness was more marked in patients with higher headache impact. This subgroup of patients more frequently reported changes in the therapeutic and care paths as the perceived cause of the occurrence of motor or extra-motor symptomatology. CONCLUSIONS: Migraine patients, especially those more severely affected, proved more vulnerable than healthy control subjects to Covid-19 lockdown. Long-lasting interruption of social interactions may be detrimental in fragile patients that are in need of structured support interventions to maintain psycho-physical wellbeing.


Subject(s)
COVID-19/complications , COVID-19/psychology , Headache/etiology , Migraine Disorders/etiology , Quarantine/psychology , Social Isolation , Social Support , Adult , Anxiety/psychology , COVID-19/epidemiology , Case-Control Studies , Communicable Disease Control , Cross-Sectional Studies , Disease Outbreaks , Female , Headache/epidemiology , Humans , Loneliness , Male , Middle Aged , Migraine Disorders/epidemiology , SARS-CoV-2
12.
J Clin Psychiatry ; 82(4)2021 07 06.
Article in English | MEDLINE | ID: covidwho-1518675

ABSTRACT

Objective: The conditions created by the COVID-19 pandemic could negatively affect maternal mental health and the mother-infant relationship. The aim of this study is to determine the impact of the COVID-19 pandemic on depression, anxiety, and mother-infant bonding among women seeking treatment for postpartum depression (PPD).Methods: Baseline data collected in two separate randomized controlled trials of a psychoeducational intervention for PPD in the same geographic region, one prior to COVID-19 (March 2019-March 2020) and one during the COVID-19 pandemic (April-October 2020), were compared. Eligible participants had an Edinburgh Postnatal Depression Scale (EPDS) score of ≥ 10, were ≥ 18 years of age, had an infant < 12 months old, and were fluent in English. Outcomes included PPD (EPDS), anxiety (Generalized Anxiety Disorder-7 [GAD-7]), and mother-infant relationship (Postpartum Bonding Questionnaire [PBQ]). All were measured continuously and dichotomized at accepted clinical cutoffs.Results: Of the 603 participants (305 pre-COVID-19; 298 during COVID-19), mothers enrolled during the COVID-19 pandemic reported higher levels of symptoms of PPD (B = 1.35; 95% CI, 0.64 to 2.06; Cohen d = 0.31) and anxiety (B = 1.52; 95% CI, 0.72 to 2.32; Cohen d = 0.30). During COVID-19, women had 65% higher odds of clinically significant levels of depression symptoms (OR = 1.65; 95% CI, 1.13 to 2.31) and 46% higher odds of clinically relevant anxiety symptoms (OR = 1.46; 95% CI, 1.05 to 2.05). However, there were no statistically significant differences in mother-infant bonding.Conclusions: The findings of this study suggest that rates and severity of PPD and anxiety symptoms among women seeking treatment for PPD have worsened in Canada during the COVID-19 pandemic. However, treatment-seeking mothers have consistently maintained good relationships with their infants. Considering the difficulties women with PPD face when accessing treatment, it is important that strategies are developed and disseminated to safely identify and manage PPD to mitigate potential long-term adverse consequences for mothers and their families.Trial Registration: ClinicalTrials.gov identifiers: NCT03654261 and NCT04485000.


Subject(s)
Anxiety/etiology , COVID-19/psychology , Depression, Postpartum/etiology , Mother-Child Relations/psychology , Mothers/psychology , Object Attachment , Pandemics , Adolescent , Adult , Anxiety/diagnosis , Anxiety/epidemiology , Anxiety/psychology , COVID-19/epidemiology , Depression, Postpartum/epidemiology , Depression, Postpartum/psychology , Female , Humans , Infant , Infant, Newborn , Ontario/epidemiology , Risk Factors , Self Report , Severity of Illness Index , Young Adult
13.
Sci Rep ; 11(1): 22305, 2021 11 12.
Article in English | MEDLINE | ID: covidwho-1514422

ABSTRACT

This study examined whether significantly anxious individuals differed from non-anxious individuals in their perceptual ratings of internet memes related to the Covid-19 pandemic, whilst considering the mediating role of emotion regulation. Eighty individuals presenting clinically significant anxiety symptoms (indicating ≥ 15 on the GAD-7) and 80 non-anxious controls (indicating ≤ 4) rated the emotional valance, humour, relatability, shareability, and offensiveness of 45 Covid-19 internet memes. A measure of emotion regulation difficulties was also completed. The perception of humour, relatability, and shareability were all greater amongst anxious individuals relative to non-anxious controls. These differences were not mediated by emotion regulation deficits. Internet memes related to the current Covid-19 pandemic may tentatively serve as coping mechanism for individuals experiencing severe symptoms of anxiety.


Subject(s)
Adaptation, Psychological , Anxiety Disorders/psychology , Anxiety/psychology , COVID-19 , Emotional Regulation , Adolescent , Adult , COVID-19/epidemiology , Emotions , Female , Humans , Internet , Male , Middle Aged , Pandemics , Social Media , Young Adult
14.
Pediatr Ann ; 50(11): e446-e448, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1512790

ABSTRACT

Anxiety is incredibly common and even normal as a waxing and waning dominant emotion for children. However, attention to disruptive symptoms that prevent daily functioning or prevent a child from thriving is within the purview of the general pediatric medical home. We review diagnosis, current tools readily accessible to every pediatrician, and treatment approaches, with special sensitivity to pandemic-related barriers and outcomes related to pediatric anxiety disorders. More than ever, the general pediatrician should be prepared to co-manage anxiety disorders with an interprofessional mental health team. [Pediatr Ann. 2021;50(11):e446-e448.].


Subject(s)
Anxiety Disorders/diagnosis , Anxiety Disorders/therapy , Anxiety/psychology , COVID-19/psychology , Anxiety Disorders/psychology , COVID-19/epidemiology , Child , Emotions , Humans , Pandemics
15.
PLoS One ; 16(11): e0259376, 2021.
Article in English | MEDLINE | ID: covidwho-1511827

ABSTRACT

BACKGROUND: People at high risk of severe illness from COVID-19 have experienced greater restrictions during the pandemic, yet there is a paucity of research exploring their lived experience. OBJECTIVES: This study explored the impact of COVID-19 on people identified as at high risk of severe illness by UK Government, and in particular, the impact of the first lockdown on access to healthcare, medications and use of technological platforms. METHODS: 1038 UK adults who identified as at high risk of severe illness from COVID-19 in line with UK Government guidance or self-identified with acute or other chronic health conditions, completed the Awareness, Attitudes and Actions survey which explored the impact of COVID-19 on access to healthcare, management of long-term health condition, mental health, and health behaviours. RESULTS: Most participants reported feelings of vulnerability, anxiety and isolation, noticed that other people changed their behaviour towards them including a feeling of being stigmatised by people not categorised as high risk. Participants described the largely negative impact that the COVID-19 lockdown had on to health-related behaviours and access to healthcare, which had resulted in large declines in mental health and wellbeing. Participants also indicated disappointment at the UK Governments response and handling of the COVID-19 lockdown. IMPLICATIONS: This study provides novel evidence of the lived experience of the first COVID-19 lockdown for people identified as at high risk of severe illness. In the context of behavioural health interventions, the ubiquity of digital technologies and their adoption into day-to-day life translates into greater potential reach than traditional interventions, and consequently, greater potential for positive public health impact. Findings should be considered by policymakers and healthcare professionals to support people now and as we transition through the recovery phase with a particular emphasis on supporting mental health and changes to the management of long-term health conditions.


Subject(s)
COVID-19/epidemiology , Mental Health , Pandemics , SARS-CoV-2/pathogenicity , Anxiety/psychology , Anxiety/virology , Attitude , COVID-19/psychology , COVID-19/virology , Communicable Disease Control/statistics & numerical data , Delivery of Health Care/statistics & numerical data , Female , Health Personnel , Humans , Male , Middle Aged , Risk Factors , Surveys and Questionnaires , United Kingdom/epidemiology
16.
PLoS One ; 16(11): e0258893, 2021.
Article in English | MEDLINE | ID: covidwho-1511820

ABSTRACT

OBJECTIVE: Explore how previous work during the 2003 Severe Acute Respiratory Syndrome (SARS) outbreak affects the psychological response of clinical and non-clinical healthcare workers (HCWs) to the current COVID-19 pandemic. METHODS: A cross-sectional, multi-centered hospital online survey of HCWs in the Greater Toronto Area, Canada. Mental health outcomes of HCWs who worked during the COVID-19 pandemic and the SARS outbreak were assessed using Impact of Events-Revised scale (IES-R), Generalized Anxiety Disorder scale (GAD-7), and Patient Health Questionnaire (PHQ-9). RESULTS: Among 3852 participants, moderate/severe scores for symptoms of post- traumatic stress disorder (PTSD) (50.2%), anxiety (24.6%), and depression (31.5%) were observed among HCWs. Work during the 2003 SARS outbreak was reported by 1116 respondents (29.1%), who had lower scores for symptoms of PTSD (P = .002), anxiety (P < .001), and depression (P < .001) compared to those who had not worked during the SARS outbreak. Multivariable logistic regression analysis showed non-clinical HCWs during this pandemic were at higher risk of anxiety (OR, 1.68; 95% CI, 1.19-2.15, P = .01) and depressive symptoms (OR, 2.03; 95% CI, 1.34-3.07, P < .001). HCWs using sedatives (OR, 2.55; 95% CI, 1.61-4.03, P < .001), those who cared for only 2-5 patients with COVID-19 (OR, 1.59; 95% CI, 1.06-2.38, P = .01), and those who had been in isolation for COVID-19 (OR, 1.36; 95% CI, 0.96-1.93, P = .05), were at higher risk of moderate/severe symptoms of PTSD. In addition, deterioration in sleep was associated with symptoms of PTSD (OR, 4.68, 95% CI, 3.74-6.30, P < .001), anxiety (OR, 3.09, 95% CI, 2.11-4.53, P < .001), and depression (OR 5.07, 95% CI, 3.48-7.39, P < .001). CONCLUSION: Psychological distress was observed in both clinical and non-clinical HCWs, with no impact from previous SARS work experience. As the pandemic continues, increasing psychological and team support may decrease the mental health impacts.


Subject(s)
COVID-19/epidemiology , COVID-19/psychology , Health Personnel/psychology , Severe Acute Respiratory Syndrome/epidemiology , Severe Acute Respiratory Syndrome/psychology , Adaptation, Psychological/physiology , Adolescent , Adult , Allied Health Personnel , Anxiety/psychology , Anxiety/virology , Anxiety Disorders/psychology , Anxiety Disorders/virology , COVID-19/virology , Canada , Cross-Sectional Studies , Depression/psychology , Depression/virology , Disease Outbreaks , Female , Humans , Male , Mental Health , Middle Aged , Outcome Assessment, Health Care , Pandemics/statistics & numerical data , Patient Health Questionnaire , Psychological Distress , SARS-CoV-2/pathogenicity , Severe Acute Respiratory Syndrome/virology , Stress Disorders, Post-Traumatic/psychology , Stress Disorders, Post-Traumatic/virology , Surveys and Questionnaires , Young Adult
17.
Eur J Psychotraumatol ; 12(1): 1984667, 2021.
Article in English | MEDLINE | ID: covidwho-1510837

ABSTRACT

Background: Research is urgently needed to understand health care workers' (HCWs') experiences of moral-ethical dilemmas encountered throughout the COVID-19 pandemic, and their associations with organizational perceptions and personal well-being. This research is important to prevent long-term moral and psychological distress and to ensure that workers can optimally provide health services. Objective: Evaluate associations between workplace experiences during COVID-19, moral distress, and the psychological well-being of Canadian HCWs. Method: A total of 1362 French- and English-speaking Canadian HCWs employed during the COVID-19 pandemic were recruited to participate in an online survey. Participants completed measures reflecting moral distress, perceptions of organizational response to the pandemic, burnout, and symptoms of psychological disorders, including depression, anxiety, and posttraumatic stress disorder (PTSD). Results: Structural equation modelling showed that when organizational predictors were considered together, resource adequacy, positive work life impact, and ethical work environment negatively predicted severity of moral distress, whereas COVID-19 risk perception positively predicted severity of moral distress. Moral distress also significantly and positively predicted symptoms of depression, anxiety, PTSD, and burnout. Conclusions: Our findings highlight an urgent need for HCW organizations to implement strategies designed to prevent long-term moral and psychological distress within the workplace. Ensuring availability of adequate resources, reducing HCW risk of contracting COVID-19, providing organizational support regarding individual priorities, and upholding ethical considerations are crucial to reducing severity of moral distress in HCWs.


Antecedentes: Se necesita con urgencia investigaciones para comprender las experiencias de los dilemas éticos y morales que los trabajadores de la salud encontraron durante la pandemia de la COVID-19 y su asociación con las percepciones de la organización y el bienestar personal. Esta investigación es importante para prevenir la angustia moral y psicológica a largo plazo y para asegurar que los trabajadores de la salud puedan proveer de manera óptima los servicios de salud.Objetivo: Evaluar la asociación entre las experiencias en el lugar de trabajo durante la COVID-19, la angustia moral y el bienestar psicológico de los trabajadores de salud canadienses.Métodos: Se reclutó a un total de 1362 trabajadores de salud canadienses, que hablaban francés e inglés y que fueron contratados durante la pandemia de la COVID-19, para participar en un cuestionario en línea. Los participantes completaron mediciones que reflejaban la angustia moral, la percepción de la respuesta de la organización a la pandemia, el burnout y los síntomas de trastornos psicológicos, que incluían a la depresión, a la ansiedad y al trastorno de estrés postraumático (TEPT).Resultados: El modelo de ecuaciones estructurales mostró que cuando los predictores de la organización se consideraban en conjunto ­ los recursos adecuados, el impacto positivo en la vida laboral y un ambiente de trabajo ético ­, predijeron negativamente la gravedad de la angustia moral, mientras que la percepción del riesgo de contraer la COVID-19 predijo positivamente la gravedad de la angustia moral. La angustia moral también predijo de manera significativa y positiva los síntomas de la depresión, la ansiedad, el TEPT y el burnout.Conclusiones: Nuestros hallazgos resaltan la urgente necesidad de que las organizaciones de trabajadores de salud implementen estrategias diseñadas para prevenir la angustia moral y psicológica a largo plazo en el lugar de trabajo. El asegurar la disponibilidad de los recursos adecuados, el reducir el riesgo de que los trabajadores de salud contraigan la COVID-19, el proveer un soporte organizacional adecuado según las prioridades individuales y el respetar las consideraciones éticas son fundamentales para reducir la gravedad de la angustia moral en los trabajadores de salud.背景:亟需研究以了解卫生保健工作者 (HCW) 在整个 COVID-19 疫情期间遇到的道德伦理困境的经历, 及其与组织观念和个人幸福感的关联。本研究对于预防长期道德和心理困扰并确保工作人员能够最好地提供健康服务非常重要。目的:评估加拿大医护人员的 COVID-19 期间工作场所经历, 道德困扰和心理健康之间的关联。方法:共招募了 1362 名在 COVID-19 疫情期间受雇的讲法语和英语的加拿大 HCW 参与在线调查。参与者完成了反映道德困扰, 组织对疫情, 倦怠和心理障碍症状 (包括抑郁, 焦虑和创伤后应激障碍 (PTSD)) 的看法的测量。结果:结构方程模型表明, 当同时考虑组织预测因素时, 资源充足性, 积极的工作生活影响和道德工作环境负向预测道德困扰的严重程度, 而 COVID-19 风险感知正向预测道德困扰的严重程度。道德困扰也显著且正向预测了抑郁, 焦虑, PTSD和倦怠的症状。结论:我们的结果强调了 HCW 组织迫切需要实施旨在预防工作场所内长期道德和心理困扰的策略。确保可获取足够资源, 降低HCW接触 COVID-19 的风险, 提供个体优先性相关的组织支持以及坚持伦理考虑对于降低医护人员道德困境的严重程度至关重要.


Subject(s)
COVID-19 , Health Personnel , Mental Health/trends , Morals , Psychological Distress , Workplace/psychology , Adult , Anxiety/psychology , Burnout, Professional/psychology , Canada , Depression/psychology , Female , Health Personnel/ethics , Health Personnel/psychology , Humans , Internet , Male , Middle Aged , Organizational Culture , Surveys and Questionnaires
18.
Ann Med ; 53(1): 2120-2131, 2021 12.
Article in English | MEDLINE | ID: covidwho-1510753

ABSTRACT

INTRODUCTION: The COVID-19 pandemic has been influencing people's psychological health, especially in pregnant women. We aimed to examine associated factors of fear of COVID-19, anxiety and depression among pregnant women during the pandemic where the impacts of healthy eating behaviour (HES) and health literacy (HL) were emphasized. METHODS: A cross-sectional study was conducted between 14 February 2020 and 31 May 2020 in 18 health centres and hospitals across Vietnam. Data of 518 pregnant women were analysed, including socio-demographics, pregnant-related factors, HES, HL, health-related behaviours, fear of COVID-19 scale (FCoV-19S), anxiety (using the generalized anxiety disorder (GAD-7)) and depression (using the patient health questionnaire with 9 items (PHQ-9)). Regression analysis was utilized to explore the associations. RESULTS: Pregnant women with higher scores of HES and HL had lower likelihood of anxiety (odds ratio, OR, 0.79; 95% confidence interval (95%CI), 0.73, 0.87; p < .001; and OR, 0.94; 95%CI, 0.90, 0.99; p = .018) and depression (OR, 0.84; 95%CI, 0.78, 0.91; p < .001; and OR, 0.96; 95%CI, 0.91, 0.99; p = .044), respectively. Pregnant women being employed had a lower FCoV-19S score (regression coefficient, B, -1.46; 95%CI, -2.51, -0.40; p = .007). Besides, other significant predictors of anxiety were eating healthier during the pandemic, unchanged or more physical activity, elevated gestational age and smoking. Other significant predictors of depression were eating healthier during the pandemic, elevated gestational age and smoking. CONCLUSIONS: Among others, HES and HL had positive impacts on protecting pregnant women against anxiety and depression. Improving HES and HL should be addressed as a strategic approach to improve reproductive health during the pandemic.KEY MESSAGEThe COVID-19 pandemic influences antenatal mental disorders with the higher level as opposed to that before the pandemic.Healthy eating behaviour and better health literacy (HL) had critical roles in lowering prenatal anxiety and depression during the COVID-19 crisis.Strategic approaches for improving healthy eating and HL should be recommended for protecting pregnant women from mental health problems during the pandemic.


Subject(s)
Anxiety/psychology , COVID-19/psychology , Depression/psychology , Diet, Healthy , Fear/psychology , Health Literacy , Pregnant Women/psychology , Adult , Anxiety/epidemiology , COVID-19/epidemiology , Cross-Sectional Studies , Depression/epidemiology , Feeding Behavior , Female , Humans , Pandemics , Pregnancy , SARS-CoV-2 , Surveys and Questionnaires
19.
Eur J Psychotraumatol ; 12(1): 1984049, 2021.
Article in English | MEDLINE | ID: covidwho-1506934

ABSTRACT

Background: Frontline healthcare workers, recovered COVID+ patients who had severe illness, and close others of COVID+ patients who have recovered or died are at risk for clinical levels of mental health symptoms in the context of the COVID-19 pandemic. RESTORE (Recovering from Extreme Stressors Through Online Resources and E-health) was specifically designed for this context. RESTORE is a transdiagnostic guided online intervention adapted from evidence-based cognitive-behavioural therapies. Objectives: RESTORE was designed to address depression, anxiety, and posttraumatic stress disorder symptoms associated with exposure to COVID-19-related traumatic and extreme stressors, and to overcome multiple barriers to accessing psychotherapies. Method: This paper describes the intervention components and platform, as well as the principles used to develop RESTORE. Current research and future directions in developing and testing RESTORE are outlined. Results: Preliminary data from an initial uncontrolled trial evaluating RESTORE in frontline healthcare workers is highly promising. Conclusion: We believe RESTORE has great potential to provide accessible, evidence-based psychological intervention to those in great need.


Antecedentes: Los trabajadores de salud de primera línea, los pacientes de COVID positivo recuperados que tenían una enfermedad grave y las personas cercanas a los pacientes de COVID positivo que se han recuperado o fallecido están en riesgo de presentar niveles clínicos de síntomas de salud mental en el contexto de la pandemia de COVID-19. RESTORE (por sus siglas en inglés: Recovering from Extreme Stressors Through Online Resources and E-health: Recuperación de estresores extremos a través de recursos en línea y salud electrónica) fue diseñada específicamente para este contexto. RESTORE es una intervención en línea guiada transdiagnóstica adaptada de terapias cognitivo-conductuales basadas en la evidencia.Objetivos: RESTORE fue diseñado para abordar la depresión, la ansiedad y los síntomas del trastorno de estrés postraumático asociados con la exposición a factores estresantes traumáticos y extremos relacionados con COVID-19, y para superar múltiples barreras para acceder a psicoterapias.Método: Este artículo describe los componentes y la plataforma de la intervención, así como los principios utilizados para desarrollar RESTORE. Se describen las investigaciones actuales y las direcciones futuras para desarrollar y testear RESTORE.Resultados: Los datos preliminares de un ensayo inicial no controlado que evalúa RESTORE en trabajadores de salud de primera línea son muy prometedores.Conclusión: Creemos que RESTORE tiene un gran potencial para brindar una intervención psicológica accesible y basada en la evidencia a quienes más lo necesitan.背景: 在 COVID-19 疫情背景下, 一线医护人员, 重症 COVID+ 康复患者以及已康复或死亡的 COVID+ 患者的其他亲友都有出现临床心理健康症状的风险。 RESTORE (通过在线资源和电子健康从极端应激源中恢复) 专为这种情况而设计。 RESTORE 是一种改编自循证认知行为疗法的跨诊断指导的在线干预。目的: RESTORE 旨在致力于 COVID-19 相关创伤性和极端应激源暴露相关的抑郁, 焦虑和创伤后应激障碍症状, 并克服心理治疗可得性的多种障碍。方法: 本文介绍了干预组成和平台, 以及用于开发RESTORE的原则。概述了开发和测试 RESTORE 的当前研究和未来方向。结果: 来自评估一线医护人员 RESTORE 的初始非对照试验的初步数据大有前景。结论: 我们相信 RESTORE 有很大的潜力为急需帮助者提供易得, 询证的心理干预。.


Subject(s)
Anxiety/therapy , COVID-19/psychology , Cognitive Behavioral Therapy , Depression/therapy , Health Personnel/psychology , Internet-Based Intervention , Stress Disorders, Post-Traumatic/therapy , Anxiety/psychology , COVID-19/epidemiology , Depression/psychology , Humans , Mental Health , Pandemics , SARS-CoV-2 , Stress Disorders, Post-Traumatic/psychology
20.
Pan Afr Med J ; 39: 271, 2021.
Article in French | MEDLINE | ID: covidwho-1505637

ABSTRACT

This study is based on a psychoanalytically inspired psychological investigation of two pregnant women with COVID-19 at different stages of pregnancy in the Department of Obstetrics and Gynaecology A at the Charles Nicolle Hospital. Our study was conducted between 2020 and 2021, until deliveries. Two young Tunisian women aged 28 and 30 years were tested positive for COVID-19 during pregnancy. They suffered from emotional shock. In this study, we discuss the different points of collision between life and death by describing, in detail, the experiences of these two women during their confinement.


Subject(s)
Anxiety/psychology , COVID-19/psychology , Pregnant Women/psychology , Stress, Psychological/psychology , Adult , COVID-19/epidemiology , COVID-19/prevention & control , Female , Humans , Mental Health , Pandemics , Pregnancy , SARS-CoV-2
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