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1.
Zh Nevrol Psikhiatr Im S S Korsakova ; 123(3): 75-81, 2023.
Article in Russian | MEDLINE | ID: mdl-36946401

ABSTRACT

OBJECTIVE: To identify the relationship between speech impairment as measured by the Russian Aphasia Test (RAT) and functional communication as assessed by the Communicative Effectiveness Index (CETI). MATERIAL AND METHODS: RAT and CETI were administered to 87 patients at two time points, before surgery and in 3 months after brain tumor resection surgery. RESULTS: There were significant correlations between CETI and the total scores on RAT subtests for speech comprehension and production before surgery but not in the follow-up period. CONCLUSION: The present research is the first to present the Russian version of CETI and to confirm the relationship between speech disorders measured by the comprehensive standardized battery for evaluating speech function RAT and functional communication as measured by CETI.


Subject(s)
Aphasia , Brain Neoplasms , Humans , Language Tests , Communication , Speech , Speech Disorders , Brain Neoplasms/complications , Brain Neoplasms/diagnosis
2.
Int J Speech Lang Pathol ; 25(1): 172-177, 2023 Feb.
Article in English | MEDLINE | ID: mdl-36927168

ABSTRACT

PURPOSE: This commentary describes how a grassroot-led partnership initiated by members of the organisations World Federation of NeuroRehabilitation and Collaboration of Aphasia Trialists is addressing the marginalisation of people with aphasia, through education and knowledge exchange related to communication partner training of health professionals. RESULT: A partnership between academics and healthcare professionals across Austria, Denmark, Egypt, Ireland, Greece, India, Serbia and the United Kingdom was established in 2020. Through bimonthly online sessions in 2021-2022 a Danish communication partner training program was introduced while six teams adapted and translated the training and its materials to their local contexts. CONCLUSION: A collaborative partnership enabled multiple translations of an existing communication partner training program for healthcare professionals working with people with aphasia to support a sustainable delivery model that is linguistic and culturally sensitive. This commentary paper focusses on Sustainable Development Goal (SDG) 17 and also addresses SDG 10.


Subject(s)
Aphasia , Sustainable Development , Humans , Austria , Egypt , Greece , Serbia , Aphasia/rehabilitation , Communication , Health Personnel/education
3.
Int J Environ Res Public Health ; 20(5)2023 Feb 22.
Article in English | MEDLINE | ID: mdl-36900945

ABSTRACT

(1) Background: The CEECCA questionnaire assesses the ability to communicate among individuals with aphasia. It was designed using the NANDA-I and NOC standardised nursing languages (SNLs), reaching high content validity index and representativeness index values. The questionnaire was pilot-tested, demonstrating its feasibility for use by nurses in any healthcare setting. This study aims to identify the psychometric properties of this instrument. (2) Methods: 47 individuals with aphasia were recruited from primary and specialist care facilities. The instrument was tested for construct validity and criterion validity, reliability, internal consistency, and responsiveness. The NANDA-I and NOC SNLs and the Boston test were used for criterion validity testing. (3) Results: five language dimensions explained 78.6% of the total variance. Convergent criterion validity tests showed concordances of up to 94% (Cohen's κ: 0.9; p < 0.001) using the Boston test, concordances of up to 81% using DCs of NANDA-I diagnoses (Cohen's κ: 0.6; p < 0.001), and concordances of up to 96% (Cohen's κ: 0.9; p < 0.001) using NOC indicators. The internal consistency (Cronbach's alpha) was 0.98. Reliability tests revealed test-retest concordances of 76-100% (p < 0.001). (4) Conclusions: the CEECCA is an easy-to-use, valid, and reliable instrument to assess the ability to communicate among individuals with aphasia.


Subject(s)
Aphasia , Humans , Psychometrics , Reproducibility of Results , Aphasia/diagnosis , Language , Surveys and Questionnaires
4.
Distúrb. comun ; 21(1): 39-46, abr. 2009.
Article in Portuguese | LILACS (Americas) | ID: biblio-1417285

ABSTRACT

O jargão ou estereotipia é uma das características da afasia. Pode-se dizer que o jargão é defi nido por segmentos de fala, em sua maioria ininteligíveis, que o paciente repete sempre que enuncia. O objetivo deste trabalho é caracterizar a fala jarganofásica de duas pacientes afásicas, a partir de uma proposta alternativa, a qual não está submetida ao raciocínio orgânico, enfatizando a relação entre sujeito-fala e seus efeitos. Os resultados mostram que a paciente M. não tem prejuízos com o laço social, ela utiliza gestos e se posiciona como falante; a paciente L. fi ca presa ao jargão e o diálogo não progride. A presença de jargão não torna os casos semelhantes e, nem tampouco, caracteriza um único tratamento. O tratamento deve priorizar a relação sujeito-língua, ou melhor, a posição do afásico na linguagem.


The jargon is characterized by fragments, segments of speaking that the pacient repeats every time he speaks. The goal of this study is to characterize the speech with jargon in two patients with aphasia. We will show an alternative proposal which is not submited to organic rational. The speech of two aphasic pacients with jargonophasia was observered to emphasize the relantionship between subject-speech and its effects. The results show that the patient M. remains in the social bond, she uses gestures and has the speaker position; the patient L. is attached to the jargon and dialogue can not proceed.The presence of jargon doesn't characterize a unique treatment. The treatment must evaluate the relationship between subject-language, in other words, the aphasics' position in language.


La jerga o estereotipia es una de las caracteristicas de la afasia. Se puede decir que la jerga es defi nida por seguimiento del habla, en su mayoría ininteligibles, que el paciente repite siempre que habla. El objetivo de este trabajo es caracterizar el habla jerganofásica de dos pacientes afásicas, a partir de una propuesta alternativa que no está sometida al raciocinio organico pero enfatiza la relacion entre sujeto-habla y sus efectos. Los resultados muestran que el la paciente M. no tiene daños en el vínculo social, utiliza gestos y se posiciona como hablante; la paciente L. queda prisionera de la jerga y el diálogo no avanza. La presencia de lo jargão no torna las casos semejante y, tampoco caracteriza un único tratamiento. El tratamiento debe privilegiar la relacion sujeto-lengua, o mejor, la posición del afásico en el lenguaje.


Subject(s)
Humans , Female , Middle Aged , Aged , Aphasia/etiology , Speech Intelligibility , Stereotyping , Aphasia/therapy , Communication , Stroke/complications
5.
Am J Speech Lang Pathol ; 32(2): 748-761, 2023 03 09.
Article in English | MEDLINE | ID: mdl-36848333

ABSTRACT

PURPOSE: Although there are several reports of attention deficits in aphasia, studies are typically limited to a single component within this complex domain. Furthermore, interpretation of results is affected by small sample size, intraindividual variability, task complexity, or nonparametric statistical models of performance comparison. The purpose of this study is to explore multiple subcomponents of attention in persons with aphasia (PWA) and compare findings and implications from various statistical methods-nonparametric, mixed analysis of variance (ANOVA), and linear mixed-effects model (LMEM)-when applied to a small sample size. METHOD: Eleven PWA and nine age- and education-matched healthy controls (HCs) completed the computer-based Attention Network Test (ANT). ANT examines the effects of four types of warning cues (no, double, central, spatial) and two flanker conditions (congruent, incongruent) to provide an efficient way to assess the three subcomponents of attention (alerting, orienting, and executive control). Individual response time and accuracy data from each participant are considered for data analysis. RESULTS: Nonparametric analyses showed no significant differences between the groups on the three subcomponents of attention. Both mixed ANOVA and LMEM showed statistical significance on alerting effect in HCs, orienting effect in PWA, and executive control effect in both PWA and HCs. However, LMEM analyses additionally highlighted significant differences between the groups (PWA vs. HCs) for executive control effect, which were not evident on either ANOVA or nonparametric tests. CONCLUSIONS: By considering the random effect of participant ID, LMEM was able to show deficits in alerting and executive control ability in PWA when compared to HCs. LMEM accounts for the intraindividual variability based on individual response time performances instead of relying on measures of central tendencies.


Subject(s)
Aphasia , Humans , Sample Size , Aphasia/diagnosis , Aphasia/etiology , Reaction Time/physiology , Executive Function/physiology , Cues
6.
J Speech Lang Hear Res ; 66(3): 1068-1084, 2023 03 07.
Article in English | MEDLINE | ID: mdl-36827514

ABSTRACT

BACKGROUND: Aphasia therapy is an effective approach to improve language function in chronic aphasia. However, it remains unclear what prognostic factors facilitate therapy response at the individual level. Here, we utilized data from the POLAR (Predicting Outcomes of Language Rehabilitation in Aphasia) trial to (a) determine therapy-induced change in confrontation naming and long-term maintenance of naming gains and (b) examine the extent to which aphasia severity, age, education, time postonset, and cognitive reserve predict naming gains at 1 week, 1 month, and 6 months posttherapy. METHOD: A total of 107 participants with chronic (≥ 12 months poststroke) aphasia underwent extensive case history, cognitive-linguistic testing, and a neuroimaging workup prior to receiving 6 weeks of impairment-based language therapy. Therapy-induced change in naming performance (measured as raw change on the 175-item Philadelphia Naming Test [PNT]) was assessed 1 week after therapy and at follow-up time points 1 month and 6 months after therapy completion. Change in naming performance over time was evaluated using paired t tests, and linear mixed-effects models were constructed to examine the association between prognostic factors and therapy outcomes. RESULTS: Naming performance was improved by 5.9 PNT items (Cohen's d = 0.56, p < .001) 1 week after therapy and by 6.4 (d = 0.66, p < .001) and 7.5 (d = 0.65, p < .001) PNT items at 1 month and 6 months after therapy completion, respectively. Aphasia severity emerged as the strongest predictor of naming improvement recovery across time points; mild (ß = 5.85-9.02) and moderate (ß = 9.65-11.54) impairment predicted better recovery than severe (ß = 1.31-3.37) and very severe (ß = 0.20-0.32) aphasia. Age was an emergent prognostic factor for recovery 1 month (ß = -0.14) and 6 months (ß = -0.20) after therapy, and time postonset (ß = -0.05) was associated with retention of naming gains at 6 months posttherapy. CONCLUSIONS: These results suggest that therapy-induced naming improvement is predictable based on several easily measurable prognostic factors. Broadly speaking, these results suggest that prognostication procedures in aphasia therapy can be improved and indicate that personalization of therapy is a realistic goal in the near future. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.22141829.


Subject(s)
Aphasia , Stroke Rehabilitation , Humans , Infant , Infant, Newborn , Aphasia/etiology , Aphasia/therapy , Aphasia/psychology , Language , Linguistics , Prognosis
7.
Undersea Hyperb Med ; 50(1): 3-7, 2023.
Article in English | MEDLINE | ID: mdl-36820801

ABSTRACT

Acute carbon monoxide (CO) intoxication may result in delayed neurological sequelae, which can include amnesia, ataxia, aphasia, emotional lability, disorientation, dysphagia, and other manifestations. A 27-year-old man reported symptoms of aphasia with agraphia and alexia in a review after CO intoxication. The patient received outpatient speech therapy, as well as repeated sessions of hyperbaric oxygen for 15 days, interspersing speech therapy with hyperbaric oxygen therapy for two months. After this period of combined treatment the aphasic symptomatology remitted, and oral and written language was normal. The complete disappearance of aphasia with agraphia and alexia confirms the efficacy of the combined intervention. More data from large clinical studies are needed to assess the outcomes of hyperbaric oxygen treatment in patients with delayed neurological sequelae after CO intoxication, but this case suggests it may be a good therapeutic option in combination with specific speech therapy.


Subject(s)
Agraphia , Aphasia , Carbon Monoxide Poisoning , Dyslexia , Hyperbaric Oxygenation , Male , Humans , Adult , Carbon Monoxide , Agraphia/complications , Agraphia/therapy , Speech Therapy , Aphasia/complications , Aphasia/therapy , Carbon Monoxide Poisoning/complications , Dyslexia/complications , Dyslexia/therapy
8.
J Commun Disord ; 102: 106314, 2023.
Article in English | MEDLINE | ID: mdl-36801532

ABSTRACT

INTRODUCTION: Several studies have examined the communicative participation of people with communication disorders (PWCD). Hindering and facilitating factors were analyzed in different population groups considering various private and public communication contexts. However, knowledge about (a) the experiences of persons with different communication disorders, (b) communication with public authorities, and (c) the perspective of communication partners in this area remains limited. Therefore, this study aimed to explore the communicative participation of PWCD with public authorities. We analyzed communicative experiences (hindering and facilitating factors) and suggestions for improving communicative access described by persons with aphasia (PWA) and persons who stutter (PWS) as well as by employees of public authorities (EPA). METHODS: In semi-structured interviews, PWA (n = 8), PWS (n = 9), and EPA (n = 11) reported specific communicative encounters with public authorities. The interviews were analyzed using qualitative content analysis, focusing on hindering/facilitating experiences and suggestions for improvement. RESULTS: The personal experiences of the participants during authority encounters were represented by the interwoven themes of familiarity and awareness, attitudes and behavior, and support and autonomy. The perspectives of the three groups overlap in several areas; however, the results also indicate specific differences between PWA and PWS as well as between PWCD and EPA. CONCLUSION: The results indicate a need to improve awareness/knowledge about communication disorders and communicative behavior in EPA. Moreover, PWCD should actively engage in encounters with authorities. In both groups, awareness must be raised about how each communication partner can contribute to successful communication, and avenues to achieve this goal must be demonstrated.


Subject(s)
Aphasia , Communication Disorders , Stuttering , Humans , Communication
9.
J Speech Lang Hear Res ; 66(3): 966-986, 2023 03 07.
Article in English | MEDLINE | ID: mdl-36791263

ABSTRACT

PURPOSE: A preliminary version of a paraphasia classification algorithm (henceforth called ParAlg) has previously been shown to be a viable method for coding picture naming errors. The purpose of this study is to present an updated version of ParAlg, which uses multinomial classification, and comprehensively evaluate its performance when using two different forms of transcribed input. METHOD: A subset of 11,999 archival responses produced on the Philadelphia Naming Test were classified into six cardinal paraphasia types using ParAlg under two transcription configurations: (a) using phonemic transcriptions for responses exclusively (phonemic-only) and (b) using phonemic transcriptions for nonlexical responses and orthographic transcriptions for lexical responses (orthographic-lexical). Agreement was quantified by comparing ParAlg-generated paraphasia codes between configurations and relative to human-annotated codes using four metrics (positive predictive value, sensitivity, specificity, and F1 score). An item-level qualitative analysis of misclassifications under the best performing configuration was also completed to identify the source and nature of coding discrepancies. RESULTS: Agreement between ParAlg-generated and human-annotated codes was high, although the orthographic-lexical configuration outperformed phonemic-only (weighted-average F1 scores of .78 and .87, respectively). A qualitative analysis of the orthographic-lexical configuration revealed a mix of human- and ParAlg-related misclassifications, the former of which were related primarily to phonological similarity judgments whereas the latter were due to semantic similarity assignment. CONCLUSIONS: ParAlg is an accurate and efficient alternative to manual scoring of paraphasias, particularly when lexical responses are orthographically transcribed. With further development, it has the potential to be a useful software application for anomia assessment. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.22087763.


Subject(s)
Aphasia , Humans , Anomia , Semantics , Neuropsychological Tests , Algorithms
10.
Behav Brain Res ; 443: 114344, 2023 04 12.
Article in English | MEDLINE | ID: mdl-36781021

ABSTRACT

Several studies with resting-state magnetic resonance imaging (rs-fMRI) have examined functional impairments and plasticity within language network in patients with post-stroke aphasia (PSA). However, there is still ubiquitous inconsistency across these studies, partly due to restricted to very small sample size and the absence of validation with follow-up data. In the current study, we aimed at providing relatively strong evidence to support functional impairments and its reorganization in PSA. Here, the amplitude of low frequency fluctuations (ALFF) and functional connectivity were used to assess functional alterations of PSA with moderate sample size at baseline (thirty-five PSA patients and thirty-five healthy controls). Functional abnormalities at baseline were observed whether improved among sixteen follow-up patients. Compared with controls, PSA at baseline presented decreased ALFF in the left inferior frontal gyrus (IFG) and decreased functional connectivity of the left IFG with the bilateral supplementary motor area (SMA) and right superior temporal gyrus (STG). The decreased ALFF in IFG, decreased IFG-SMA and IFG-STG connectivity were enhanced among follow-up patients and was synchronized with language-performance improvement. Our results revealed reduced intrinsic neural activity and inter-connections within language network in PSA, which would be normalized synchronously as the improvement of language performance.


Subject(s)
Aphasia , Humans , Magnetic Resonance Imaging/methods , Language , Temporal Lobe , Prefrontal Cortex , Brain , Brain Mapping/methods
11.
PLoS One ; 18(2): e0281335, 2023.
Article in English | MEDLINE | ID: mdl-36753505

ABSTRACT

BACKGROUND: Chinese idioms have potential to act as preliminary training material in studies on post-stroke aphasia. OBJECTIVE: To explore an extension speech training program that takes Chinese idioms as context and expands them into characters, words, sentences and paragraphs and evaluate the effects of this program in patients with post-stroke non-fluent aphasia. METHODS: This was a randomized controlled trial. We recruited patients with post-stroke non-fluent aphasia from the Renmin Hospital of Wuhan University from January 2021 to January 2022. Participants were randomly assigned to group I and group II. Patients in group I had treatment with extension speech training based on Chinese idioms, and those in group II had treatment with conventional speech rehabilitation training. The training period in both groups was 40 min daily for 2 weeks. RESULTS: A total of 70 patients (group I, n = 34; and group II, n = 36) completed the trial and were analyzed according to protocol. There were no significant differences in baseline values between both groups. After intervention, the scores of oral expression, comprehension, and reading in the Aphasia Battery Of Chinese scale and the scores of the Comprehensive Activities of Daily Living questionnaire significantly improved in both groups (P <0.05), with group I benefiting more (P <0.05). CONCLUSION: This extension speech training program based on Chinese idioms can improve the language function and daily communication ability of the patients with post-stroke non-fluent aphasia. TRIAL REGISTRATION: Chinese Clinical Trial Registry ChiCTR2000031825.


Subject(s)
Aphasia , Stroke Rehabilitation , Stroke , Humans , Stroke Rehabilitation/methods , Speech , Activities of Daily Living , East Asian People , Treatment Outcome , Aphasia/etiology , Aphasia/rehabilitation , Stroke/complications , Speech Therapy/methods , Language
12.
Brain Topogr ; 36(2): 135-171, 2023 03.
Article in English | MEDLINE | ID: mdl-36749552

ABSTRACT

Background Magnetoencephalography (MEG) and electroencephalography (EEG) record two main types of data: continuous measurements at rest or during sleep, and event-related potentials/evoked magnetic fields (ERPs/EMFs) that involve specific and repetitive tasks. In this systematic review, we summarized longitudinal studies on recovery from post-stroke aphasia that used continuous or event-related temporal imaging (EEG or MEG). Methods We searched PubMed and Scopus for English articles published from 1950 to May 31, 2022. Results 34 studies were included in this review: 11 were non-interventional studies and 23 were clinical trials that used specific rehabilitation methods, neuromodulation, or drugs. The results of the non-interventional studies suggested that poor language recovery was associated with slow-wave activity persisting over time. The results of some clinical trials indicated that behavioral improvements were correlated with significant modulation of the N400 component. Discussion Compared with continuous EEG, ERP/EMF may more reliably identify biomarkers of therapy-induced effects. Electrophysiology should be used more often to explore language processes that are impaired after a stroke, as it may highlight treatment challenges for patients with post-stroke aphasia.


Subject(s)
Aphasia , Stroke , Humans , Male , Female , Electroencephalography , Evoked Potentials/physiology , Aphasia/etiology , Stroke/complications , Magnetoencephalography
13.
Stroke ; 54(3): 831-839, 2023 03.
Article in English | MEDLINE | ID: mdl-36734234

ABSTRACT

BACKGROUND: Stroke is a leading cause of long-term disability. Greater rehabilitation therapy after stroke is known to improve functional outcomes. This study examined therapy doses during the first year of stroke recovery and identified factors that predict rehabilitation therapy dose. METHODS: Adults with new radiologically confirmed stroke were enrolled 2 to 10 days after stroke onset at 28 acute care hospitals across the United States. Following an initial assessment during acute hospitalization, the number of physical therapy, occupational therapy, and speech therapy sessions were determined at visits occurring 3, 6, and 12 months following stroke. Negative binomial regression examined whether clinical and demographic factors were associated with therapy counts. False discovery rate was used to correct for multiple comparisons. RESULTS: Of 763 patients enrolled during acute stroke admission, 510 were available for follow-up. Therapy counts were low overall, with most therapy delivered within the first 3 months; 35.0% of patients received no physical therapy; 48.8%, no occupational therapy, and 61.7%, no speech therapy. Discharge destination was significantly related to cumulative therapy; the percentage of patients discharged to an inpatient rehabilitation facility varied across sites, from 0% to 71%. Most demographic factors did not predict therapy dose, although Hispanic patients received a lower cumulative amount of physical therapy and occupational therapy. Acutely, the severity of clinical factors (grip strength and National Institutes of Health Stroke Scale score, as well as National Institutes of Health Stroke Scale subscores for aphasia and neglect) predicted higher subsequent therapy doses. Measures of impairment and function (Fugl-Meyer, modified Rankin Scale, and Stroke Impact Scale Activities of Daily Living) assessed 3 months after stroke also predicted subsequent cumulative therapy doses. CONCLUSIONS: Rehabilitative therapy doses during the first year poststroke are low in the United States. This is the first US-wide study to demonstrate that behavioral deficits predict therapy dose, with patients having more severe deficits receiving higher doses. Findings suggest directions for identifying groups at risk of receiving disproportionately low rehabilitation doses.


Subject(s)
Aphasia , Occupational Therapy , Stroke Rehabilitation , Stroke , Adult , Humans , United States , Activities of Daily Living , Stroke/therapy , Recovery of Function
14.
J Speech Lang Hear Res ; 66(2): 668-687, 2023 02 13.
Article in English | MEDLINE | ID: mdl-36729701

ABSTRACT

PURPOSE: Increasingly, mechanisms of learning are being considered during aphasia rehabilitation. Well-characterized learning mechanisms can inform "how" interventions should be administered to maximize the acquisition and retention of treatment gains. This systematic scoping review mapped hypothesized mechanisms of action (MoAs) and treatment ingredients in three learning-based approaches targeting naming in aphasia: errorless learning (ELess), errorful learning (EFul), and retrieval practice (RP). The rehabilitation treatment specification system was leveraged to describe available literature and identify knowledge gaps within a unified framework. METHOD: PubMed and CINHAL were searched for studies that compared ELess, EFul, and/or RP for naming in aphasia. Independent reviewers extracted data on proposed MoAs, treatment ingredients, and outcomes. RESULTS: Twelve studies compared ELess and EFul, six studies compared ELess and RP, and one study compared RP and EFul. Hebbian learning, gated Hebbian learning, effortful retrieval, and models of incremental learning via lexical access were proposed as MoAs. To maximize treatment outcomes within theorized MoAs, researchers manipulated study ingredients including cues, scheduling, and feedback. Outcomes in comparative effectiveness studies were examined to identify ingredients that may influence learning. Individual-level variables, such as cognitive and linguistic abilities, may affect treatment response; however, findings were inconsistent across studies. CONCLUSIONS: Significant knowledge gaps were identified and include (a) which MoAs operate during ELess, EFul, and RP; (b) which ingredients are active and engage specific MoAs; and (c) how individual-level variables may drive treatment administration. Theory-driven research can support or refute MoAs and active ingredients enabling clinicians to modify treatments within theoretical frameworks.


Subject(s)
Aphasia , Learning , Humans , Aphasia/psychology , Cues , Treatment Outcome
15.
J Integr Neurosci ; 22(1): 24, 2023 Jan 17.
Article in English | MEDLINE | ID: mdl-36722227

ABSTRACT

BACKGROUND: The left primary motor area (M1) stimulation has recently been revealed to promote post-stroke aphasia (PSA) recovery, of which a plausible mechanism might be the semantic and/or the mirror neuron system reorganization, but the direct evidence is still scarce. The aim of this study was to explore the functional connectivity (FC) alterations induced by the left M1 intermittent theta burst stimulation (iTBS), a new transcranial magnetic stimulation paradigm, in the semantic and mirror neuron systems of PSA patients. METHODS: Sixteen PSA patients accepted the left M1 iTBS and underwent a resting-state functional magnetic resonance image (fMRI) scanning before and immediately after the first session of iTBS, of which six underwent another fMRI scanning after twenty sessions of iTBS. Three brain networks covering the semantic and the mirror neuron systems were constructed using the fMRI data, and the FC alterations following one-session iTBS were investigated in the networks. Additional seed-based FC analyses were conducted to explore the longitudinal FC patterns changes during the course of multi-session iTBS. The Aphasia quotient of the Chinese version of the western aphasia battery (WAB-AQ) was used to assess the severity of the language impairments of the participants. The relationship between the longitudinal WAB-AQ and network FC changes was analyzed by Spearman's correlation coefficients in the multi-session iTBS sub-group. RESULTS: Decreased FCs were noted in the bilateral semantic rather than in the mirror neuron networks following one-session of iTBS (p < 0.05, network based statistical corrected). Longitudinal seed-based FC analyses revealed changing FC ranges along the multi-session iTBS course, extending beyond the semantic networks. No significant relationship was found between the longitudinal WAB-AQ and network FC changes in the multi-session iTBS sub-group. CONCLUSIONS: The left M1 iTBS might induce FC changes in the semantic system of PSA patients. CLINICAL TRIAL REGISTRATION: This research was registered on the Chinese Clinical Trial Registry website (http://www.chictr.org.cn/index.aspx), and the registration number is ChiCTR2100041936.


Subject(s)
Aphasia , Language Disorders , Humans , Semantic Web , Aphasia/etiology , Language , Brain/diagnostic imaging
16.
Geriatr Psychol Neuropsychiatr Vieil ; 20(4): 483-496, 2022 12 01.
Article in French | MEDLINE | ID: mdl-36700441

ABSTRACT

Asyntactic comprehension corresponds to a disorder in the comprehension of sentences, which is one of the difficulties that can arise in a context of aphasia following a stroke. To date, rehabilitation of asyntactic comprehension is divided into three main groups of approaches, centered on the structure of the sentence, on the memory or on the verb and its thematic roles. The present study aims to assess the effectiveness of the existing treatments to rehabilitate asyntactic comprehension in post-stroke aphasic individuals, in terms of post-treatment improvements, generalization, long-term maintenance and transfer effects to daily life activities. A systematic review of the literature was carried out and twenty-four studies presenting seven different treatments, were selected, involving a total of 148 post-stroke aphasic patients. The methodological quality of each study has been analyzed following the Santiago-Delefosse grid or the MMAT grid. In general, the analysis of the measures of effectiveness (post-treatment improvement, generalization, maintenance, and transfer effects) showed that the treatments whose approach was centered on the structure of the sentence or on the working memory are those allowing to significantly improve syntactic comprehension for individuals with aphasia. The short-term memory approach did not show improvement in syntactic comprehension but remains little studied. And the approach based on the verb and its thematic roles is so far too understudied to draw a clear conclusion. The present study contributes to the advancement of knowledge on syntactic rehabilitation in the context of post-stroke aphasia leadind to various clinical implications for an informed choice. The few studies available on the subject as well as the few data collected constitute, among other things, a limit to this study.


La compréhension asyntaxique correspond à un trouble de la compréhension de phrases dans le cadre d'une aphasie faisant suite à un accident vasculaire cérébral (AVC). À ce jour, les approches de la rééducation de la compréhension asyntaxique se répartissent selon qu'elles sont centrées sur la structure de la phrase, sur la mémoire ou sur le verbe. La présente étude vise à évaluer l'efficacité de ces approches pour améliore la compréhension asyntaxique chez ces personnes. Après une revue systématique de la littérature, un total de 24 études présentant sept traitements différents et regroupant 148 patients ont été sélectionnées. L'analyse des mesures d'efficacité (amélioration post-traitement, généralisation, maintien et transfert) a montré que les traitements dont l'approche est centrée sur la structure de la phrase ou sur la mémoire de travail ont permis d'améliorer significativement la compréhension syntaxique. Le traitement basé sur la mémoire à court terme n'a pas montré d'amélioration de la compréhension syntaxique mais reste peu étudié et le traitement axé sur le verbe est à ce jour trop peu étudié pour tirer une conclusion claire. La présente étude contribue à l'avancement des connaissances sur la rééducation syntaxique bien que plus d'études soient nécessaires pour augmenter les données à jour.


Subject(s)
Aphasia , Stroke , Humans , Comprehension , Aphasia/etiology , Stroke/complications , Language , Memory, Short-Term
17.
J Neuroeng Rehabil ; 20(1): 12, 2023 01 24.
Article in English | MEDLINE | ID: mdl-36694257

ABSTRACT

BACKGROUND: Stroke is a significant contributor of worldwide disability and morbidity with substantial economic consequences. Rehabilitation is a vital component of stroke recovery, but inpatient stroke rehabilitation programs can struggle to meet the recommended hours of therapy per day outlined by the Canadian Stroke Best Practices and American Heart Association. Mobile applications (apps) are an emerging technology which may help bridge this deficit, however this area is understudied. The purpose of this study is to review the effect of mobile apps for stroke rehabilitation on stroke impairments and functional outcomes. Specifically, this paper will delve into the impact of varying mobile app types on stroke rehabilitation. METHODS: This systematic review included 29 studies: 11 randomized control trials and 18 quasi-experimental studies. Data extrapolation mapped 5 mobile app types (therapy apps, education apps, rehab videos, reminders, and a combination of rehab videos with reminders) to stroke deficits (motor paresis, aphasia, neglect), adherence to exercise, activities of daily living (ADLs), quality of life, secondary stroke prevention, and depression and anxiety. RESULTS: There were multiple studies supporting the use of therapy apps for motor paresis or aphasia, rehab videos for exercise adherence, and reminders for exercise adherence. For permutations involving other app types with stroke deficits or functional outcomes (adherence to exercise, ADLs, quality of life, secondary stroke prevention, depression and anxiety), the results were either non-significant or limited by a paucity of studies. CONCLUSION: Mobile apps demonstrate potential to assist with stroke recovery and augment face to face rehabilitation, however, development of a mobile app should be carefully planned when targeting specific stroke deficits or functional outcomes. This study found that mobile app types which mimicked principles of effective face-to-face therapy (massed practice, task-specific practice, goal-oriented practice, multisensory stimulation, rhythmic cueing, feedback, social interaction, and constraint-induced therapy) and education (interactivity, feedback, repetition, practice exercises, social learning) had the greatest benefits. Protocol registration PROPSERO (ID CRD42021186534). Registered 21 February 2021.


Subject(s)
Aphasia , Mobile Applications , Stroke Rehabilitation , Stroke , Humans , Activities of Daily Living , Canada , Quality of Life , Stroke Rehabilitation/methods
18.
Sensors (Basel) ; 23(2)2023 Jan 11.
Article in English | MEDLINE | ID: mdl-36679654

ABSTRACT

The rehabilitation of aphasics is fundamentally based on the assessment of speech impairment. Developing methods for assessing speech impairment automatically is important due to the growing number of stroke cases each year. Traditionally, aphasia is assessed manually using one of the well-known assessment batteries, such as the Western Aphasia Battery (WAB), the Chinese Rehabilitation Research Center Aphasia Examination (CRRCAE), and the Boston Diagnostic Aphasia Examination (BDAE). In aphasia testing, a speech-language pathologist (SLP) administers multiple subtests to assess people with aphasia (PWA). The traditional assessment is a resource-intensive process that requires the presence of an SLP. Thus, automating the assessment of aphasia is essential. This paper evaluated and compared custom machine learning (ML) speech recognition algorithms against off-the-shelf platforms using healthy and aphasic speech datasets on the naming and repetition subtests of the aphasia battery. Convolutional neural networks (CNN) and linear discriminant analysis (LDA) are the customized ML algorithms, while Microsoft Azure and Google speech recognition are off-the-shelf platforms. The results of this study demonstrated that CNN-based speech recognition algorithms outperform LDA and off-the-shelf platforms. The ResNet-50 architecture of CNN yielded an accuracy of 99.64 ± 0.26% on the healthy dataset. Even though Microsoft Azure was not trained on the same healthy dataset, it still generated comparable results to the LDA and superior results to Google's speech recognition platform.


Subject(s)
Aphasia , Speech Perception , Stroke , Humans , Aphasia/diagnosis , Aphasia/rehabilitation , Speech Disorders , Language , Speech
20.
Zhongguo Zhen Jiu ; 43(1): 25-8, 2023 Jan 01.
Article in Chinese | MEDLINE | ID: mdl-36633235

ABSTRACT

OBJECTIVE: To observe the effect of Kaiqiao Jieyin acupuncture (acupuncture for opening orifices and relieving aphasia) combined with repetitive transcranial magnetic stimulation (rTMS) on language ability and daily life communication ability in patients with post-stroke aphasia (PSA). METHODS: Fifty-six patients with PSA were randomly divided into an observation group and a control group, 28 cases in each group. Both groups received routine symptomatic treatment. The control group was treated with speech rehabilitation training and rTMS. On the basis of the treatment in the control group, the observation group was treated with Kaiqiao Jieyin acupuncture at the speech area Ⅰ, Fengchi (GB 20), Tongli (HT 5), Lianquan (CV 23), Panglianquan (Extra), etc. Panglianquan (Extra) on both sides were connected to electroacupuncture, with intermittent wave, 2 Hz in frequency. The above treatment was performed once a day for 5 consecutive days, followed by 2 days of rest for 2 weeks. The scores of western aphasia battery (WAB, including scores of spontaneous speech, auditory comprehension, repetition, naming and score of aphasia quotient [AQ]) and communication abilities in daily living (CADL) in the two groups were compared before and after treatment. RESULTS: After treatment, the spontaneous speech, auditory comprehension, repetition, naming scores and AQ scores in both groups were higher than those before treatment (P<0.05), and the increase in the observation group was greater than the control group (P<0.05). The CADL scores of the two groups were higher than those before treatment (P<0.05). CONCLUSION: Kaiqiao Jieyin acupuncture combined with rTMS can improve the language ability and daily life communication ability of PSA patients.


Subject(s)
Acupuncture Therapy , Aphasia , Stroke Rehabilitation , Humans , Transcranial Magnetic Stimulation , Treatment Outcome , Aphasia/etiology , Aphasia/therapy
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