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J Int Med Res ; 49(11): 3000605211056783, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1533180

ABSTRACT

The ongoing global administration of vaccines for coronavirus disease 2019 (COVID-19) means that increasing numbers of patients are likely to present with post-vaccination complications. We describe the first reported case of neuralgic amyotrophy (NA) involving the lumbosacral plexus occurring after AstraZeneca COVID-19 vaccination. The patient presented with acute-onset leg paralysis following administration of the vaccine. Based on the clinical, electrodiagnostic, and radiologic findings, the patient was diagnosed with post-vaccination NA. We speculate that the COVID-19 vaccine elicited an immune-mediated inflammatory response to the injected antigen due to inflammatory immunity in a patient with predisposed susceptibility to NA.


Subject(s)
Brachial Plexus Neuritis , COVID-19 , Brachial Plexus Neuritis/chemically induced , Brachial Plexus Neuritis/diagnosis , COVID-19 Vaccines , Humans , Leg , Lumbosacral Plexus , Paraplegia , SARS-CoV-2 , Vaccination/adverse effects
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