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Pacing Clin Electrophysiol ; 44(9): 1607-1615, 2021 09.
Article in English | MEDLINE | ID: covidwho-1295109


Several cardiovascular diseases and arrhythmic disorders have been described in COVID-19 era as likely related to SARS-CoV-2 infection. The prognostic relevance of bradyarrhythmias during the infection has not been yet described and no data are available about long-term heart conduction disorders. A review of literature concerning the association between hypokinetic arrhythmias and COVID-19 from January 2020 to February 2021 was performed. The key-words used for the research were: "sinus node disfunction," "sick sinus syndrome (SSS)," "sino-atrial block," "atrio-ventricular block (AVB)," "bradyarrhythmias," and "COVID-19″ or "SARS-CoV-2.″ Excluding "relative bradycardia," a total of 38 cases of bradyarrhythmia related to SARS-CoV-2 infection have been described, even in very young people, requiring in many cases a definitive pacemaker implantation. Furthermore, we report a case of non-hospitalized 47-years old man with a SSS developed as a consequence of mild SARS-CoV-2 infection. While in all described cases heart conduction disorders were found at presentation of the infection or during hospitalization for COVID-19, in our case the diagnosis of SSS was made after the resolution of the infection. Although rarely, heart conduction disorders may occur during COVID-19 and the present case highlights that a cardiological follow up may be desirable even after the resolution of infection, especially in the presence of symptoms suggesting a possible heart involvement.

Bradycardia/virology , COVID-19/complications , Sick Sinus Syndrome/virology , Bradycardia/physiopathology , Bradycardia/therapy , Electrocardiography , Humans , Male , Middle Aged , Pacemaker, Artificial , Prognosis , SARS-CoV-2 , Sick Sinus Syndrome/physiopathology , Sick Sinus Syndrome/therapy
J Investig Med High Impact Case Rep ; 9: 23247096211013185, 2021.
Article in English | MEDLINE | ID: covidwho-1221733


There has been an accumulating evidence of association between COVID-19 (coronavirus disease 2019) infection and cardiovascular complications. We describe a case of a 58-year-old lady with a history of systolic heart failure and COVID-19 infection, who developed persistent symptomatic bradycardia, requiring pacemaker placement as unusual conductive tissue involvement of this novel coronavirus.

Bradycardia/diagnosis , Bradycardia/virology , COVID-19/complications , Bradycardia/therapy , Diagnosis, Differential , Electrocardiography , Female , Humans , Middle Aged , Pacemaker, Artificial , SARS-CoV-2
Emerg Infect Dis ; 26(10): 2504-2506, 2020 Oct.
Article in English | MEDLINE | ID: covidwho-627531


Coronavirus disease is reported to affect the cardiovascular system. We showed that relative bradycardia was a common characteristic for 54 patients with PCR-confirmed mild-to-moderate coronavirus disease in Japan. This clinical sign could help clinicians to diagnose this disease.

Body Temperature , Bradycardia/virology , Coronavirus Infections/complications , Coronavirus Infections/physiopathology , Heart Rate , Pneumonia, Viral/complications , Pneumonia, Viral/physiopathology , Adult , Aged , Aged, 80 and over , Betacoronavirus , COVID-19 , Coronavirus Infections/diagnostic imaging , Female , Humans , Japan , Male , Middle Aged , Pandemics , Patient Acuity , Pneumonia, Viral/diagnostic imaging , Retrospective Studies , SARS-CoV-2 , Young Adult