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1.
G Ital Med Lav Ergon ; 44(1): 93, 2022 Mar.
Article in English | MEDLINE | ID: covidwho-2101833

ABSTRACT

SUMMARY: To the editor, during these pandemic years, COVID-19 is taking away focus from other respiratory diseases such as pneumoconiosis, which should not be overlooked. We would like to emphasize the possible role of small airways in subjects with asbestos exposure. In a very interesting study, Yang et al (1) investigated the relation between increased small airway obstruction and asbestos exposure in patients with asbestosis. The authors evaluated lung function in a cohort of 281 patients with newly diagnosed asbestosis during an eight-year period, evidencing that patients with asbestosis have small airway obstructive defects that are significantly associated with asbestos exposure (1). These results are very consistent and in line with our previous study, in which we showed that a population of 655 long-term residents in an environmental asbestos (tremolite)-exposed area had a higher prevalence of smallairways disease compared to a group of 653 individuals living in areas not tremolite-exposed (2). Odds Ratio for small-airways obstruction was 3.46, irrespective of smoking status (2). To date, our knowledge on the role of small airways in pulmonary diseases is still matter of debate. Although small airways have a minor contribution to airway resistance in healthy subjects, it has been shown that small airways are the major site of airflow limitation in diseases such as asthma and Chronic Obstructive Pulmonary Disease (3). Taken these data together, we warmly encourage clinicians and researchers to always consider small airways parameters when performing lung function on asbestosexposed subjects. Moreover, long-term investigations are warranted to explore the decline in airflow over time in patients with either occupational or environmental asbestos exposure and with asbestosis.


Subject(s)
Airway Obstruction , Asbestos , Asbestosis , COVID-19 , Occupational Exposure , Humans , Asbestosis/epidemiology , COVID-19/epidemiology , Asbestos/adverse effects , Airway Obstruction/complications , Risk Factors , Occupational Exposure/adverse effects
2.
G Ital Med Lav Ergon ; 44(1): 32-40, 2022 Mar.
Article in English | MEDLINE | ID: covidwho-2101747

ABSTRACT

SUMMARY: SARS-CoV-2-related infection can determine hospital-acquired infections among patients and healthcare workers. Aim of this paper was to review the literature for developing a strategy for protecting healthcare workers, patients, and visitors by COVID-19 hospital infection. A critical and rapid revision of the literature and international standards and Regulations on this topic allowed us to propose an evidencebased strategy in the framework of the workplace risk assessment for preventing nosocomial COVID-19 outbreaks. The virus' high transmissibility, the high prevalence of asymptomatic carriers and false-negative Covid-19 rates on naso- and oropharingeal swabs, put hospitals at high-risk of COVID-19 outbreaks. A comprehensive strategy based on standard precautions, administrative, environmental, and engineering controls, a screening protocol for patients on their admission to hospital, and a testing-based strategy for HCWs within health surveillance programs may prevent the onset of hospital outbreaks, which are a threat to community, patients and HCWs, compromising the sustainability of healthcare facilities.


Subject(s)
COVID-19 , Humans , COVID-19/epidemiology , COVID-19/prevention & control , SARS-CoV-2 , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Infection Control , Health Personnel , Hospitals
3.
Orthopade ; 51(5): 385-394, 2022 May.
Article in German | MEDLINE | ID: covidwho-1798515

ABSTRACT

No appeal by a health politician, no matter how insistent, has ever forced all the operational structures of our health-care system to examine their own efficiencies and cost reduction potentials as has SARS-CoV­2. Fast-track surgery, developed long before the current pandemic, can become an indispensable element of modern hospital routines through the integration of interlocked care structures. Patient satisfaction and clinical outcome can be improved by significantly shortening hospital stays, decreasing complication rates, and by additionally strengthening the competence and motivation of the patients involved. Hospital staff could be relieved of heavy workloads, and overall costs could be reduced by involving external prehabilitation centers. It is now necessary to further develop standards for the establishment and implementation of appropriately coordinated prehabilitation and rehabilitation concepts for elective total hip and knee replacement surgery and, ideally, to save resources at the same time through regional networking and integration.


Subject(s)
Arthroplasty, Replacement, Hip , Arthroplasty, Replacement, Knee , COVID-19 , Ambulatory Care , Arthroplasty, Replacement, Hip/rehabilitation , COVID-19/epidemiology , Humans , Length of Stay , Outpatients , Preoperative Exercise , SARS-CoV-2
4.
Acta Odontol Latinoam ; 35(2): 134-143, 2022 Sep 30.
Article in English | MEDLINE | ID: covidwho-2101107

ABSTRACT

The SARS-Cov-2 (COVID-19) pandemic changed the educational structure of dentistry courses and highlighted the importance of online tools. Understanding students' perception regarding these changes is essential to establishing future teaching-learning strategies to accommodate students' needs in higher education. The aim of this study was to assess students' perceptions of the Oral Radiology teachinglearning process before and during the COVID-19 pandemic. The sample consisted of students (n = 111) of the 2nd, 4th and 6th semesters of the dentistry course, who answered a questionnaire with 21 items: A) Students' demographic data (5 questions); B) Students' teaching-learning experiences during the pre-pandemic period (8 questions); and C) Students' teaching-learning experiences during the post-pandemic period (8 questions). Stuart-Maxwell tests revealed statistically significant differences between students' opinions before and during the pandemic when they were asked about the structure of the Oral Radiology module (p = 0.008); their previous experience with e-learning and teaching (p < 0.001); their thoughts about the importance of e-learning in Oral Radiology (p < 0.05); and the time they spent online for academic purposes (p < 0.05). Students seem to prefer on-campus activities (before COVID-19), but the pandemic increased their awareness of the importance of e-learning, the time they spent on online studies, and their knowledge of online educational tools.


A pandemia de SARS-Cov-2 (COVID-19) mudou a estrutura educacional dos cursos de odontologia e destacou a importância das ferramentas online. Compreender a percepção dos alunos sobre as mudanças vivenciadas é essencial para estabelecer futuras estratégias de ensino-aprendizagem e acomodar as necessidades dos alunos no ensino superior. Este estudo teve como objetivo avaliar a percepção dos alunos sobre o processo de ensino-aprendizagem de Radiologia Odontológica antes e durante a pandemia de COVID-19. A amostra foi composta por alunos (n = 111) do 2º, 4º e 6º semestres do curso de odontologia que responderam a um questionário com 21 itens: A) Dados demográficos dos alunos (5 questões); B) Experiências de ensino-aprendizagem dos alunos no período pré-pandemia (8 questões); e C) Experiências de ensino-aprendizagem dos alunos no período pós-pandemia (8 questões). Os testes de Stuart-Maxwell revelaram diferenças estatisticamente significativas entre as opiniões dos alunos antes e durante as pandemias quando questionados sobre a estrutura do módulo de Radiologia Odontológica (p = 0,008); sua experiência anterior com ensino a distância (p < 0,001); seus pensamentos relacionados à importância da Radiologia Odontológica via e-learning (p < 0,05); e o tempo gasto online para fins acadêmicos (p < 0,05). Os alunos parecem preferir atividades no campus (antes do COVID-19), mas as pandemias aumentaram sua conscientização sobre a importância do e-learning, seu tempo dedicado aos estudos online e sua familiarização com ferramentas educacionais online.


Subject(s)
COVID-19 , Radiology , Humans , COVID-19/epidemiology , Pandemics , SARS-CoV-2 , Students
5.
Asian Pac J Cancer Prev ; 23(10): 3265-3271, 2022 Oct 01.
Article in English | MEDLINE | ID: covidwho-2100938

ABSTRACT

PURPOSE: This study aims to measure the occupational fatigue level and describe the sources and consequences of occupational fatigue among middle and higher management at an international specialized cancer center during the COVID-19 pandemic. METHODS: A mixed-method design was used in this study. A convenience sampling technique was utilized to select the participants from King Hussein Cancer Center, Amman, Jordan. The data was collected through a self-administered questionnaire. This questionnaire included both quantitative and qualitative sections. We utilized Fatigue Risk Assessment and Management in High-Risk Environments (FRAME)-26 items scale for the quantitative section. Two main questions were included in the survey to identify the sources and consequences of occupational fatigue. RESULTS: The results show that the average mean of occupational fatigue was 2.95/5 (SD=0.70). The level of changes in fatigue levels after the COVID-19 pandemic increased by 0.87/3 (SD=1.45). The sources of occupational fatigue could be categorized into five themes: workload, work environment, staffing, psychological, and physical sources. There are four themes categorizing occupational fatigue: social, economic, health, and daily activity and lifestyle. CONCLUSION: This study affords valuable insight into the level, source, and consequences of occupational fatigue among middle and higher management at an international specialized cancer hospital in developing countries. The results indicate that the occupational fatigue level was moderate, and the fatigue level was negatively impacted by the COVID-19 pandemic.


Subject(s)
COVID-19 , Neoplasms , Humans , COVID-19/epidemiology , Pandemics , Fatigue/epidemiology , Fatigue/etiology , Workplace , Workload/psychology , Neoplasms/epidemiology
6.
Asian Pac J Cancer Prev ; 23(5): 1497-1504, 2022 May 01.
Article in English | MEDLINE | ID: covidwho-2100936

ABSTRACT

OBJECTIVE: A systematic review and meta-analysis were carried out to assess the pooled proportion of women screened for cervical cancer before and during the COVID-19 pandemic. METHODS: After ruling out registered or ongoing systematic reviews in the PROSPERO database regarding the impact of the COVID-19 pandemic in cervical cancer screening, the protocol of our systematic review and meta-analysis was registered in PROSPERO (CRD42021279305). The electronic databases were searched for articles published in English between January 2020 and October 2021and the study was designed based on PRISMA guidelines updated in 2020. Meta-analysis was accomplished in STATA version 13.0 (College Station, Texas 77,845 USA). The pooled proportion of women who had undergone cervical cancer screening was reported with 95% CI. In order to quantify the heterogeneity, Chi2 statistic (Q statistic) and I2 index were used. RESULTS: The meta-analysis included seven studies from Slovenia, Italy, Ontario (Canada), Scotland, Belgium, and the USA, comprising 403,986 women and 199,165 women who were screened for cervical cancer before the COVID-19 pandemic in 2019 and during the pandemic in 2020, respectively. The pooled proportion of women screened for cervical cancer in 2019 was 9.79% (95% CI 6.00%-13.59%, 95% prediction interval 0.42%-23.81%). During the pandemic, the pooled proportion of screened women declined to 4.24% (95% CI 2.77%-5.71%, 95% prediction interval 0.9%-17.49%). CONCLUSION: There was a substantial drop in the cervical cancer screening rate due to lockdowns and travel restrictions to curb the COVID-19 pandemic. Scaling up cervical cancer screening strategies is essential to prevent the long-term impact of cervical cancer burden.


Subject(s)
COVID-19 , Uterine Cervical Neoplasms , COVID-19/diagnosis , COVID-19/epidemiology , Communicable Disease Control , Early Detection of Cancer , Female , Humans , Pandemics/prevention & control , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/epidemiology
7.
Aust J Gen Pract ; 51(11): 879-883, 2022 11.
Article in English | MEDLINE | ID: covidwho-2100931

ABSTRACT

BACKGROUND: International travel is resuming, but the COVID-19 pandemic has radically changed the context in terms of regulation, risks and models of travel. OBJECTIVE: Providing travel health advice is an important role for general practice. The aim of this article is to cover the changed context and wide-ranging implications of the COVID­19 pandemic for travel health advice. DISCUSSION: Travel in the COVID-19 era requires travellers to be well informed and prepared to comply with complex and evolving public health measures. There are changing patterns of infectious disease risk related to the impacts of the pandemic, increasing antimicrobial resistance and climate change. New models of travel include a shift towards greater environmental sustainability.


Subject(s)
COVID-19 , Pandemics , Humans , Pandemics/prevention & control , COVID-19/epidemiology , COVID-19/prevention & control , Travel , Family Practice , Data Collection
8.
Iran J Med Sci ; 47(6): 588-593, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-2100905

ABSTRACT

Background: Previous studies have shown that patients with epilepsy (PWE) perceived significant disruption in the quality and provision of care due to the coronavirus disease 2019 (COVID-19) pandemic. The present study aimed to investigate the effect of this pandemic on seizure control status and changes in seizure frequency in PWE. Methods: A consecutive sample of adult PWE registered in the database of Shiraz Epilepsy Center (Shiraz, Iran) was included in the study. In July 2021, phone interviews were conducted with all selected patients. Information such as age, sex, last seizure, seizure type, and frequency during the 12 months before the study, and history of COVID-19 contraction was extracted. The seizure control status of the patients in 2019 (pre-pandemic) was compared with that during the COVID-19 pandemic. Data were analyzed using SPSS software with the Fisher's exact test and Pearson's Chi squared test. P<0.05 was considered statistically significant. Results: A total of 158 patients were included in the study, out of which 62 (39.2%) patients had a stable seizure control status, 47 (29.7%) had fewer seizures, and 50 (31.6%) had more seizures. Breakthrough seizures were reported by 32 (34.4%) patients. Seizure frequency increased in 18 (27.7%) and decreased in 46 (70.7%) patients. Conclusion: Overall, the COVID-19 pandemic has not been a major precipitating factor nor has it affected the seizure control status of PWE. In treated epilepsy, a fluctuating course with periods of seizure freedom followed by relapses is part of its natural history.


Subject(s)
COVID-19 , Epilepsy , Adult , Humans , Infant , Pandemics , COVID-19/epidemiology , Seizures/epidemiology , Epilepsy/complications , Epilepsy/epidemiology , Recurrence
9.
Cir Cir ; 90(5): 602-609, 2022.
Article in English | MEDLINE | ID: covidwho-2100847

ABSTRACT

BACKGROUND: The Mexican Hepato-Pancreato-Biliary Association (AMHPB) conducted a survey, aiming to gather experience and opinions of HPB surgeons about HPB surgery in the 2020 COVID-19 pandemic year. METHODS: An online survey was conducted (33 items: demographics, patient referral, COVID-19 screening and limitations, hospital occupancy and surgical practice) to AMHPB members and attendees of the previous meetings of the Society through a self-administered questionnaire. Answers were excluded if respondents were not from Latin America. RESULTS: 88 participants answered (47.5 ± 10 years, 94% male and 65.9% Mexicans). About 8% worked in COVID-19 converted hospitals. About 1.1% did not perform pre-operative COVID-19 testing. Polymerase chain reaction (33%) was the most common COVID-19 pre-operative test. The number of patient referrals decreased 62.5%. About 29.5% had one patient who died from COVID-19 during preoperative surgical evaluation. About 64.7% answered that surgical case volume decreased. About 17% and 23% respondents considered that surgical morbidity and mortality increased, respectively. Hospital resources and COVID-19 infection were responsible for change in surgical outcomes. Lack of ICU beds (54%) was the most common cause of surgical cancellation. CONCLUSION: COVID-19 had a strong negative impact on HPB surgery in Mexico and Latin America in terms of patient reference, case volume and surgical outcomes.


INTRODUCCIÓN: La Asociación Mexicana Hepato-Pancreato-Biliar (AMHPB) realizó una encuesta con el objetivo de recopilar experiencias/opiniones de cirujanos HPB sobre cirugía HPB en el 2020 con pandemia COVID-19. MÉTODOS: Se realizó encuesta virtual (33 ítems: demografía, derivación de pacientes, tamizaje/limitaciones COVID-19, ocupación hospitalaria y práctica quirúrgica) a miembros de la AMHPB y asistentes a reuniones previas de la Sociedad a través de un cuestionario autoadministrado. Se excluyeron las respuestas que no fueran de América Latina. RESULTADOS: Respondieron 88 participantes (47.5 ± 10 años, 94% hombres y 65.9% mexicanos). 8% trabajaba en hospitales reconvertidos COVID-19. 1,1% no realizó prueba COVID-19 preoperatoria. La Polymerase chain reaction (33%) fue laprueba preoperatoria COVID-19 más común. Lareferencia de pacientes disminuyó 62,5%. El 29,5% tuvo paciente fallecido por COVID-19 durante la evaluación preoperatoria. 64,7% respondió que el volumen de casos quirúrgicos disminuyó. El 17% y23% consideraron que la morbilidad y mortalidad quirúrgicas aumentaron respectivamente. Los recursos hospitalarios e infección por COVID-19 influyeron en los resultados quirúrgicos. La falta de camas de UCI (54%) fue lo más común en cancelación quirúrgica. CONCLUSIÓN: COVID-19 tuvo un fuerte impacto negativo en la cirugía HPB en México y América Latina en referencia de pacientes, volumen de casos y resultados quirúrgicos.


Subject(s)
COVID-19 , Digestive System Surgical Procedures , Male , Humans , Female , COVID-19/epidemiology , Pandemics , Latin America/epidemiology , Mexico/epidemiology , COVID-19 Testing , Surveys and Questionnaires
10.
Cir Cir ; 90(5): 670-677, 2022.
Article in English | MEDLINE | ID: covidwho-2100846

ABSTRACT

OBJECTIVE: To determine the clinical-demographic characteristics of patients recovered from COVID-19 in a third level rehabilitation service. METHOD: A cross-sectional and descriptive study of recovered COVID-19 patients in a rehabilitation service was carried out. Demographic, personal pathological history, his work activity and COVID-19 were taken, as well as alterations after the disease. Descriptive statistics were performed. RESULTS: 186 files were collected. The mean age was 48.04 ± 11.32 years. Male predominance was found (65.6%). 50% of the patients were health workers. The most common previous pathological conditions were sedentary lifestyle (73.7%) and diabetes mellitus (29%). 43.5% presented grade 3 dyspnea according to the modified Medical Research Council scale. There was a high prevalence of neuromuscular involvement, predominantly peripheral neuropathy (48.4%) and dysautonomia (46.2%). CONCLUSIONS: It was possible to determine the clinical-demographic characteristics of patients recovered from COVID-19 in a third-level rehabilitation service, such as age, sex, type of work, previous pathological conditions (diabetes mellitus and arterial hypertension), body mass index, dyspnea, hospitalization, and post-illness disorders. Further investigation of COVID-19 is needed in the development of conditions to different systems.


OBJETIVO: Determinar las características clínico-demográficas de pacientes recuperados de COVID-19 en un servicio de rehabilitación de tercer nivel. MÉTODO: Se realizó un estudio transversal y descriptivo de pacientes recuperados de COVID-19 en un servicio de rehabilitación. Se tomaron antecedentes demográficos, personales patológicos, de su actividad laboral y de COVID-19, así como alteraciones posteriores a la enfermedad. Se realizó estadística descriptiva. RESULTADOS: Se recolectaron 186 expedientes. La edad media fue de 48.04 ± 11.32 años. Se encontró predominio del sexo masculino (65.6%). El 50% de los pacientes eran trabajadores de la salud. Las condiciones patológicas previas más comunes fueron sedentarismo (73.7%) y diabetes mellitus (29%). El 43.5% presentaron disnea de grado 3 acorde a la escala Medical Research Council modificada. Existió alta prevalencia de compromiso neuromuscular, predominando la neuropatía periférica (48.4%) y la disautonomía (46.2%). CONCLUSIONES: Se logró determinar las características clínico-demográficas de pacientes recuperados de COVID-19 en un servicio de rehabilitación de tercer nivel, como la edad, el sexo, el tipo de trabajo, las condiciones patológicas previas (diabetes mellitus e hipertensión arterial), el índice de masa corporal, la disnea, la hospitalización y las alteraciones posteriores a la enfermedad. Es necesaria mayor investigación de la COVID-19 en el desarrollo de afecciones en diferentes sistemas.


Subject(s)
COVID-19 , Humans , Male , Adult , Middle Aged , Female , Cross-Sectional Studies , COVID-19/epidemiology , Dyspnea/etiology , Retrospective Studies
11.
In Vivo ; 36(6): 2986-2992, 2022.
Article in English | MEDLINE | ID: covidwho-2100684

ABSTRACT

BACKGROUND/AIM: To report long-term survival results after trimodal approach for locally advanced rectal cancer (LARC) in the Covid-19 era. We herein illustrate a clinical application of Covid-death mean-imputation (CoDMI) algorithm in LARC patients with Covid-19 infection. PATIENTS AND METHODS: We analyzed 94 patients treated for primary LARC. Overall survival was calculated in months from diagnosis to first event (last follow-up/death). Because Covid-19 death events potentially bias survival estimation, to eliminate skewed data due to Covid-19 death events, the observed lifetime of Covid-19 cases was replaced by its corresponding expected lifetime in absence of the Covid-19 event using the CoDMI algorithm. Patients who died of Covid-19 (DoC) are mean-imputed by the Kaplan-Meier estimator. Under this approach, the observed lifetime of each DoC patient is considered as an "incomplete data" and is extended by an additional expected lifetime computed using the classical Kaplan-Meier model. RESULTS: Sixteen patients were dead of disease (DoD), 1 patient was DoC and 77 cases were censored (Cen). The DoC patient died of Covid-19 52 months after diagnosis. The CoDMI algorithm computed the expected future lifetime provided by the Kaplan-Meier estimator applied to the no-DoC observations as well as to the DoC data itself. Given the DoC event at 52 months, the CoDMI algorithm estimated that this patient would have died after 79.5 months of follow-up. CONCLUSION: The CoDMI algorithm leads to "unbiased" probability of overall survival in LARC patients with Covid-19 infection, compared to that provided by a naïve application of Kaplan-Meier approach. This allows for a proper interpretation/use of Covid-19 events in survival analysis. A user-friendly version of CoDMI is freely available at https://github.com/alef-innovation/codmi.


Subject(s)
COVID-19 , Radiation Oncology , Humans , Kaplan-Meier Estimate , COVID-19/epidemiology , Survival Analysis , Algorithms
12.
In Vivo ; 36(6): 2823-2827, 2022.
Article in English | MEDLINE | ID: covidwho-2100683

ABSTRACT

BACKGROUND/AIM: COVID-19 is a concerning issue among in-center hemodialysis (HD) patients. To prevent COVID-19 diffusion in our HD facility, weekly rapid nasal antigen test screening was performed for all asymptomatic patients on chronic HD. This study aimed to assess the performance of weekly rapid antigen test in detecting SARS-CoV-2 infection among asymptomatic patients receiving HD. PATIENTS AND METHODS: A retrospective analysis was conducted in HD patients who underwent rapid antigen test screening from December 2021 to March 2022. The diagnosis of COVID-19 with rapid antigen test was always confirmed by reverse transcriptase-polymerase chain reaction (RT-PCR). RESULTS: During the observational period, 1,748 rapid antigen tests were performed in 220 HD patients. Mean age was 68.4±14.6 years. Fifteen (8.5%) patients resulted positive for SARS-CoV-2 infection using rapid antigen tests. The diagnosis was subsequently confirmed in 14 (93.3%) patients by RT-PCR. During the same period, 12 (5.4%) symptomatic patients, regularly screened with weekly rapid antigen test, resulted positive for SARS-CoV-2 infection using RT-PCR. Overall, weekly rapid antigen test screening identified 14 out of 26 (53.8%) COVID-19 cases and showed a positive predictive value of 93%. CONCLUSION: Weekly antigen test screening of asymptomatic patients on chronic HD detected around half of the COVID-19 cases in our population.


Subject(s)
COVID-19 , Humans , Middle Aged , Aged , Aged, 80 and over , COVID-19/diagnosis , COVID-19/epidemiology , SARS-CoV-2 , Retrospective Studies , COVID-19 Testing , Renal Dialysis , Sensitivity and Specificity
13.
In Vivo ; 36(6): 2806-2812, 2022.
Article in English | MEDLINE | ID: covidwho-2100681

ABSTRACT

BACKGROUND/AIM: The coronavirus disease 2019 (COVID-19) pandemic has reduced hospital visits due to concerns regarding infection and also resulted in cancer screening delays. These changes may have had an impact on the progression of colorectal cancer (CRC). Therefore, the present study investigated the effects of the COVID-19 pandemic on minimally invasive surgery (MIS) for CRC using a correlation analysis of clinical outcomes before and during the COVID-19 pandemic. PATIENTS AND METHODS: The present study targeted CRC patients who underwent MIS between January 2018 and December 2019 (pre-COVID-19) and between April 2020 and March 2021 (COVID-19). A comparison analysis of clinical, surgical, and pathological findings between the pre-COVID-19 and COVID-19 groups was performed. RESULTS: Ninety-one patients underwent MIS for CRC pre-COVID-19 and 67 during COVID-19. The number of CRC cases detected by fecal occult blood tests was slightly higher in the pre-COVID-19 group than that in the COVID-19 group. Re-evaluations of laparoscopic videos revealed that the number of cases of surgical T4 CRC resected with the combined resection of the adjacent organs was significantly higher in the COVID-19 group than that in the pre-COVID-19 group (16.4 vs. 4.4%, p=0.010). Furthermore, surgical times were significantly longer in the COVID-19 group than those in the pre-COVID-19 group (p<0.001). Pathological findings showed that the number of pT4 cases was significantly higher in the COVID-19 group than that in the pre-COVID-19 group (p=0.026). CONCLUSION: The number of T4 CRC cases was higher during than before the COVID-19 pandemic, with increases in the surgical difficulty of MIS.


Subject(s)
COVID-19 , Colorectal Neoplasms , Humans , Pandemics , COVID-19/epidemiology , Japan/epidemiology , Minimally Invasive Surgical Procedures/methods , Colorectal Neoplasms/diagnosis , Colorectal Neoplasms/epidemiology , Colorectal Neoplasms/surgery
14.
In Vivo ; 36(6): 2800-2805, 2022.
Article in English | MEDLINE | ID: covidwho-2100680

ABSTRACT

BACKGROUND/AIM: This study aimed to determine whether psychological stress associated with the COVID-19 pandemic might exacerbate lower urinary tract symptoms (LUTS) and decrease lower urinary tract function in outpatients with LUTS. PATIENTS AND METHODS: We evaluated 104 patients who visited our hospital during the first wave of the COVID-19 pandemic. Psychological stress was evaluated by the Stress Response Scale-18 (SRS-18). Subjects were divided into aggravation and non-aggravation of psychological stress groups according to the SRS-18. LUTS was evaluated according to the International Prostate Symptom Score (IPSS). Lower urinary tract function was evaluated as the post-void residual urine volume (PVR). Comparisons of scores and changes in scores of each parameter before versus during/after the first wave of the COVID-19 pandemic were performed between the two groups. RESULTS: Forty-two patients were included in each group. We observed no significant differences in the comparison of scores at each time point and in changes in total IPSS score, voiding symptom subscores and PVR between the two groups. Although no significant differences in storage symptom subscores were observed between the two groups, changes in storage symptom subscores increased significantly during the first wave of the pandemic in the aggravation of psychological stress group (p=0.02). However, no significant increase was observed after the first wave. CONCLUSION: Psychological stress during the COVID-19 pandemic might transiently aggravate storage symptoms in patients with LUTS. Physicians should be aware of the possibility of transient worsening of LUTS during future pandemics, and transiently additional medication might be effective in such patients.


Subject(s)
COVID-19 , Lower Urinary Tract Symptoms , Prostatic Hyperplasia , Male , Humans , Prostatic Hyperplasia/drug therapy , Pandemics , COVID-19/complications , COVID-19/epidemiology , Lower Urinary Tract Symptoms/epidemiology , Lower Urinary Tract Symptoms/etiology , Lower Urinary Tract Symptoms/diagnosis , Stress, Psychological
15.
Int J Yoga Therap ; 32(2022)2022 Jan 01.
Article in English | MEDLINE | ID: covidwho-2100570

ABSTRACT

To avoid severe courses of COVID-19 infections and reduce death rates, vaccination against the SARS-CoV-1 virus was considered an essential strategy in fighting the pandemic. However, some yoga practitioners reject such vaccinations and assume that their yoga practices protect them. We therefore aimed to analyze how many yoga practitioners were vaccinated, their reasons for being vaccinated, and the influence of the ethical principles of yoga (yamas/niyamas) on these decisions. In a cross-sectional survey in summer 2021, we enrolled 1,545 yoga practitioners (86% women; mean age 51.1 ± 10.9 y). The majority of participants were already vaccinated (66%), and their percentage corresponded to that of the general population. Those who were not willing to get vaccinated scored significantly higher on the yama/niyama factors Contentment/Self-Reflection/Devotion and Surrender and Non-Possessiveness. Depending on the centrality of the yamas/niyamas in their lives, yoga participants differed on their vaccination decisions, but they did not relevantly differ on their pro-social reasons (protection of groups at risk, protection of family) when they were already vaccinated. This assumed protection against severe courses of the COVID-19 infection was higher in the nonvaccinated compared to the vaccinated individuals (Cohen's d = 0.99). This conviction was related to the niyama factor Contentment/Self-Reflection/Devotion and Surrender. Thus, in the yoga schools and other places of yoga practice the relevance of vaccination to also protect others should be discussed, and the consequences of following the yamas and niyamas for the sake of others should be clarified.


Subject(s)
COVID-19 , Yoga , Humans , Female , Adult , Middle Aged , Male , SARS-CoV-2 , COVID-19/epidemiology , COVID-19/prevention & control , Cross-Sectional Studies , Vaccination , Germany
16.
MMWR Morb Mortal Wkly Rep ; 71(44): 1401-1406, 2022 Nov 04.
Article in English | MEDLINE | ID: covidwho-2100531

ABSTRACT

On August 31, 2022, the Food and Drug Administration (FDA) authorized bivalent formulations of BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) COVID-19 vaccines; these vaccines include mRNA encoding the spike protein from the original (ancestral) strain of SARS-CoV-2 (the virus that causes COVID-19) and from the B.1.1.529 (Omicron) variants BA.4 and BA.5 (BA.4/BA.5). These bivalent mRNA vaccines were authorized for use as a single booster dose ≥2 months after completion of primary series or monovalent booster vaccination; Pfizer-BioNTech bivalent booster was authorized for persons aged ≥12 years and Moderna for adults aged ≥18 years.*,† On September 1, 2022, the Advisory Committee on Immunization Practices (ACIP) recommended that all persons aged ≥12 years receive an age-appropriate bivalent mRNA booster dose.§ To characterize the safety of bivalent mRNA booster doses, CDC reviewed adverse events and health impacts reported after receipt of bivalent Pfizer-BioNTech and Moderna booster doses during August 31-October 23, 2022, to v-safe,¶ a voluntary smartphone-based U.S. safety surveillance system established by CDC to monitor adverse events after COVID-19 vaccination, and the Vaccine Adverse Event Reporting System (VAERS),** a U.S. passive vaccine safety surveillance system managed by CDC and FDA (1). During August 31-October 23, 2022, approximately 14.4 million persons aged ≥12 years received a bivalent Pfizer-BioNTech booster dose, and 8.2 million adults aged ≥18 years received a bivalent Moderna booster dose.†† Among the 211,959 registrants aged ≥12 years who reported receiving a bivalent booster dose to v-safe, injection site and systemic reactions were frequently reported in the week after vaccination (60.8% and 54.8%, respectively); fewer than 1% of v-safe registrants reported receiving medical care. VAERS received 5,542 reports of adverse events after bivalent booster vaccination among persons aged ≥12 years; 95.5% of reports were nonserious and 4.5% were serious events. Health care providers and patients can be reassured that adverse events reported after a bivalent booster dose are consistent with those reported after monovalent doses. Health impacts after COVID-19 vaccination are less frequent and less severe than those associated with COVID-19 illness (2).


Subject(s)
COVID-19 Vaccines , COVID-19 , Adult , Humans , United States/epidemiology , Adolescent , COVID-19 Vaccines/adverse effects , COVID-19/epidemiology , COVID-19/prevention & control , BNT162 Vaccine , SARS-CoV-2 , Vaccines, Synthetic/adverse effects , RNA, Messenger
17.
Med Sci Monit ; 28: e938243, 2022 Nov 01.
Article in English | MEDLINE | ID: covidwho-2100413

ABSTRACT

BACKGROUND The COVID-19 pandemic affected many people worldwide, including those with chronic diseases. Our objective was to analyze its influence on medical care and the course of inflammatory bowel disease (IBD) in Poland. MATERIAL AND METHODS In 2021, 81 patients in Poland with IBD completed an original anonymous questionnaire about the impact of the COVID-19 pandemic on the course of their disease and mental status. The printed questionnaire was distributed to IBD patients treated at the Gastroenterology Outpatient Clinic of the University Clinical Hospital in Bialystok, and an online questionnaire was sent to patients via social media. Statistical analysis was performed using the chi-squared test, with a significance level of P<0.05. RESULTS The study group consisted of 46 women and 35 men with a mean age of 32.42 years. Fifty-nine patients had ulcerative colitis and 22 had Crohn disease. Patients reported significant deterioration in medication availability (50.62%) and restricted access to gastroenterology outpatient clinics (51.90%) (P<0.05). Of patients who contracted COVID-19, 89.47% did not require hospitalization, 32.10% (26/81) were asymptomatic, mild, or moderate, despite immunosuppressive biological treatment (27.16%, 22/81), or steroids (18.52%, 15/81). Over 50% of respondents stated the pandemic negatively affected their mental state and 30% of them associated that with worsening IBD. CONCLUSIONS During the pandemic, respondents were mainly concerned with difficulties in accessing the gastroenterology clinic and limited drug availability. The pandemic negatively affected patients' mental state. In cases of COVID-19 disease, patients with IBD were mostly asymptomatic and did not require hospitalization, despite therapy affecting the immune system.


Subject(s)
COVID-19 , Inflammatory Bowel Diseases , Male , Humans , Female , Adult , COVID-19/epidemiology , Pandemics , Quality of Life , Poland/epidemiology , Inflammatory Bowel Diseases/epidemiology , Inflammatory Bowel Diseases/drug therapy , Surveys and Questionnaires , Chronic Disease
18.
Biomedica ; 42(Sp. 2): 73-77, 2021 10 31.
Article in English, Spanish | MEDLINE | ID: covidwho-2100342

ABSTRACT

INTRODUCTION: More than 90% of children infected with COVID-19 worldwide developed mild to moderate disease. In Colombia, during 2020, COVID-19 infections in children stayed below 9.2% of the total cases, with no trends for age group or sex. OBJECTIVE: To estimate the incidence of acute respiratory symptoms and COVID-19 in children from public schools in Bogotá, Colombia during the second semester of 2020. MATERIAL AND METHODS: A telephone survey was conducted in over 5,000 scholar children. Antecedents and use of health services were informed. Descriptive statistics were used. RESULTS: A total of 151.470 persons per day accounting for an IR of 157,8 per 100,000 people; almost three times the rate reported by the official surveillance system in the city. CONCLUSION: A lack of diagnosis and consultation in children was found compared to the general population. Further research is needed to elucidate the true burden of the disease in children.


Introducción. Más del 90% de los niños infectados con COVID-19 en el mundo, desarrollaron enfermedad leve a moderada. En Colombia, durante el 2020, la infección del COVID-19 en niños se mantuvo por debajo de 9,2 % del total de los casos sin tendencias por grupo de edad o sexo. Objetivo. Estimar la incidencia de síntomas respiratorios agudos y COVID19 en niños de escuelas públicas en Bogotá (Colombia) durante el segundo semestre de 2020. Materiales y métodos. Se hizo una encuesta telefónica en más de 5.000 escolares. Se recolectó información de antecedentes médicos y uso de servicios de salud. La información obtenida se describió mediante estadística descriptiva. Resultados. Se contabilizó un total de 151.470 personas al día para una tasa de incidencia de 157,8 en 100.000 personas, casi tres veces la tasa reportada por el sistema de vigilancia oficial de la ciudad. Conclusión. Se encontraron deficiencias en el diagnóstico y consulta de los niños, al compararlos con la población general. Se necesita más investigación para dilucidar la verdadera carga de la enfermedad en la población infantil.


Subject(s)
COVID-19 , Child , Humans , Colombia/epidemiology , COVID-19/epidemiology , Incidence , Schools
19.
J Atheroscler Thromb ; 29(11): 1571-1587, 2022 Nov 01.
Article in English | MEDLINE | ID: covidwho-2100246

ABSTRACT

AIMS: Declines in cardiovascular diseases during the first surge of coronavirus disease 2019 (COVID-19) have been reported. With the repeating surges of COVID-19, we aim to investigate the medium-term impact of the COVID-19 pandemic on the practice of percutaneous coronary interventions (PCIs). METHODS: We performed a descriptive analysis of rates of PCIs, utilizing administrative data in Japan. Changes in the proportion of severe cases and in-hospital mortality since the start of the COVID-19 pandemic were investigated using interrupted time series (ITS) analyses. RESULTS: From April 2018 to February 2021, 38,696 and 28,585 cases of elective and emergency PCIs, respectively, were identified. The rates of PCIs decreased during the first and third COVID-19 surges. The ratios of monthly rates of elective PCIs to that in the corresponding months during the previous 2 years were 50.3% in May 2020 and 76.1% in January 2021. The decrease in rates of emergency PCIs was smaller than that of elective PCIs. The ITS analyses did not identify any significant changes in the proportion of severe cases and in-hospital mortality. CONCLUSIONS: We found that the impacts of COVID-19 on PCIs were larger in the first surge than in the subsequent and larger in the elective than in the emergency; this continued over the medium-term. During the COVID-19 pandemic, in-hospital mortality of cases undertaking emergency PCIs did not change.


Subject(s)
COVID-19 , Percutaneous Coronary Intervention , Humans , Pandemics , COVID-19/epidemiology , Japan/epidemiology , Hospital Mortality
20.
Ann Glob Health ; 88(1): 94, 2022.
Article in English | MEDLINE | ID: covidwho-2100231

ABSTRACT

Background: Since 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in >554M cases and >6.3M deaths worldwide. The disease caused by SARS-CoV-2, COVID-19, has resulted in a broad range of clinical symptoms differing in severity. Initially, the elderly were identified as particularly susceptible to severe COVID-19, with children experiencing less severe disease. However, as new variants arise, the epidemiology of SARS-CoV-2 infection is changing, and the disease severity in children is increasing. While environmental impacts on COVID-19 have been described, the underlying mechanisms are poorly described. Objective: The Pacific Basin Consortium for Environment and Health (PBC) held meeting on September 16, 2021, to explore environmental impacts on infectious diseases, including COVID-19. Methods: The PBC is an international group of environmental scientists and those interested in health outcomes. The PBC met to present preliminary data and discuss the role of exposures to airborne pollutants in enhancing susceptibility to and severity of respiratory tract viral infections, including COVID-19. Findings: Analysis of the literature and data presented identified age as an important factor in vulnerability to air pollution and enhanced COVID-19 susceptibility and severity. Mechanisms involved in increasing severity of COVID-19 were discussed, and gaps in knowledge were identified. Conclusions: Exposure to particulate matter (PM) pollution enhanced morbidity and mortality to COVID-19 in a pediatric population associated with induction of oxidative stress. In addition, free radicals present on PM can induce rapid changes in the viral genome that can lead to vaccine escape, altered host susceptibility, and viral pathogenicity. Nutritional antioxidant supplements have been shown to reduce the severity of viral infections, inhibit the inflammatory cytokine storm, and boost host immunity and may be of benefit in combating COVID-19.


Subject(s)
Air Pollution , COVID-19 , Virus Diseases , Child , Humans , Aged , COVID-19/epidemiology , SARS-CoV-2 , Air Pollution/adverse effects , Particulate Matter/adverse effects , Particulate Matter/analysis , Environment
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